• Fisheries and Aquatic Sciences
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• v.14 no.1
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• pp.31-42
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• 2011

Three novel hepcidin isoforms were isolated and characterized from the perciform fish species Oplegnathus fasciatus. These hepcidin isoforms (designated rbhepc5, rbhepc6 and rbhepc7) were found to share a conserved, tripartite gene structure and a considerable sequence homology one another. A comparison of their mature peptide sequences with those of other perciform hepcidin orthologs indicated that these three hepcidin isoforms as well as four other isoforms previously identified in this species, appear to belong to the HAMP2 group of hepcidin genes. Analysis of the 5'-upstream sequences showed that the proximal non-coding regions of rbhepc5~7 do not possess canonical TATA signals; instead, they harbor several binding motifs for transcription factors involved in immune modulation. Reverse transcriptase-PCR analysis demonstrated that the rbhepc5~7 are expressed predominantly in the liver, and that the transcription of rbhepc5~7 is rapidly induced in the liver, but not in other tissues, by experimental challenge with any of three different bacterial species. However, transcription of rbhepc6 appeared to be negligible under both basal and stimulated conditions, as judged by the redundancy count of randomly chosen reverse transcriptase-PCR clones.

• International Journal of Contents
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• v.5 no.2
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• pp.6-15
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• 2009

Recently many different programming languages have emerged for the development of bioinformatics applications. In addition to the traditional languages, languages from open source projects such as BioPerl, BioPython, and BioJava have become popular because they provide special tools for biological data processing and are easy to use. However, it is not well-studied which of these programming languages will be most suitable for a given bioinformatics task and which factors should be considered in choosing a language for a project. Like many other application projects, bioinformatics projects also require various types of tasks. Accordingly, it will be a challenge to characterize all the aspects of a project in order to choose a language. However, most projects require some common and primitive tasks such as file I/O, text processing, and basic computation for counting, translation, statistics, etc. This paper presents the benchmarking results of six popular languages, Perl, BioPerl, Python, BioPython, Java, and BioJava, for several common and simple bioinformatics tasks. The experimental results of each language are compared through quantitative evaluation metrics such as execution time, memory usage, and size of the source code. Other qualitative factors, including writeability, readability, portability, scalability, and maintainability, that affect the success of a project are also discussed. The results of this research can be useful for developers in choosing an appropriate language for the development of bioinformatics applications.

• Journal of Korea Multimedia Society
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• v.20 no.6
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• pp.893-910
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• 2017

In this paper, we propose a simple online multiple object (human) tracking method, LKDeep (Lucas-Kanade feature and Detection based Simple Online Multiple Object Tracker), which can run in fast online enough on CPU core only with acceptable tracking performance for embedded surveillance purpose. The proposed LKDeep is a pragmatic hybrid approach which tracks multiple objects (humans) mainly based on LK features but is compensated by detection on periodic times or on necessity times. Compared to other state-of-the-art multiple object tracking methods based on 'Tracking-By-Detection (TBD)' approach, the proposed LKDeep is faster since it does not have to detect object on every frame and it utilizes simple association rule, but it shows a good object tracking performance. Through experiments in comparison with other multiple object tracking (MOT) methods using the public DPM detector among online state-of-the-art MOT methods reported in MOT challenge [1], it is shown that the proposed simple online MOT method, LKDeep runs faster but with good tracking performance for surveillance purpose. It is further observed through single object tracking (SOT) visual tracker benchmark experiment [2] that LKDeep with an optimized deep learning detector can run in online fast with comparable tracking performance to other state-of-the-art SOT methods.

• Journal of Chest Surgery
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• v.45 no.6
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• pp.390-395
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• 2012

Background: Conventional open repair is a suboptimal therapy for blunt traumatic aortic injury (BTAI) due to the high postoperative mortality and morbidity rates. Recent advances in the thoracic endovascular repair technique may improve outcomes so that it becomes an attractive therapeutic option. Materials and Methods: From August 2003 to March 2012, 21 patients (mean age, 45.81 years) with BTAI were admitted to our institution. Of these, 18 cases (open repair in 11 patients and endovascular repair in 7 patients) were retrospectively reviewed and the early perioperative results of the two groups were compared. Results: Although not statistically significant, there was a trend toward the reduction of mortality in the endovascular repair group (18.2% vs. 0%). There were no cases of paraplegia or endoleak. Statistically significant reductions in heparin dosage, blood loss, and transfusion amounts during the operations and in procedure duration were observed. Conclusion: Compared with open repair, endovascular repair can be performed with favorable mortality and morbidity rates. However, relatively younger patients who have acute aortic arch angulation and a small aortic diameter may be a therapeutic challenge. Improvements in graft design, delivery sheaths, and graft durability are the cornerstone of successful endovascular repair.

• The Journal of Society for e-Business Studies
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• v.12 no.4
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• pp.17-27
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• 2007

This paper proposes a key distribution and authentication protocol between user, service provider and key distribution center (KDC). This protocol is based on symmetric cryptosystem, challenge-response, Diffie-Hellman component and hash function. In the proposed protocol, user and server update the session key under token-update operation, and user can process repeated efficient authentications by using updated session keys. And another merit is that KDC needs not to totally control the session key between user and server in proposed protocol. Even an attacker steals the parameters from the KDC, the attacker still can not calculate session key. According to the comparison and analysis with other protocols, our proposed protocol provides good efficiency and forward secure session key.

• Membrane and Water Treatment
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• v.1 no.3
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• pp.193-206
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• 2010

Organic fouling and biofouling pose a significant challenge to the membrane filtration process. Photocatalysis-membrane hybrid system is a novel idea for reducing these membranes fouling however, when $TiO_2 photocatalyst nanoparticles are used in suspension, catalyst recovery is not only imposes an extra step on the process but also significantly contributes to increased membrane resistance and reduced permeate flux. In this study, $TiO_2$ photocatalyst has been immobilized by coating on the microfiltration (MF) membrane surface to minimize organic and microbial fouling. Nano-sized $TiO_2$ was first synthesized by a sol-gel method. The synthesized $TiO_2$ was coated on a Poly Vinyl Difluoride (PVDF) membrane (MF) surface using spray coating and dip coating techniques to obtain hybrid functional composite membrane. The characteristics of the synthesized photocatalyst and a functional composite membrane were studied using numerous instruments in terms of physical, chemical and electrical properties. In comparison to the clean PVDF membrane, the $TiO_2$ coated MF membrane was found more effective in removing methylene blue (20%) and E-coli (99%).

• Current Optics and Photonics
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• v.1 no.6
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• pp.642-648
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• 2017

Involuntary hand tremor has been a serious challenge in micromanipulation tasks and thus draws a significant amount of attention from related fields. To minimize the effect of the hand tremor, a variety of mechanically assistive solutions have been proposed. However, approaches increasing human awareness of their own hand tremor have not been extensively studied. In this paper, a head mount display based virtual reality (VR) system to increase human self-awareness of hand tremor is proposed. It shows a user a virtual image of a handheld device with emphasized hand tremor information. Provided with this emphasized tremor information, we hypothesize that subjects will control their hand tremor more effectively. Two methods of emphasizing hand tremor information are demonstrated: (1) direct amplification of tremor and (2) magnification of virtual object, in comparison to the controlled condition without emphasized tremor information. A human-subject study with twelve trials was conducted, with four healthy participants who performed a task of holding a handheld gripper device in a specific direction. The results showed that the proposed methods achieved a reduced level of hand tremor compared with the control condition.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.8 no.5
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• pp.173-179
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• 2008

An ad hoc network is multi-hop wireledss formed by mobile node without infrastructure. Due to the mobility of nodes in mobile ad hoc networks, the topology of network changes frequently. In this environments, multicast protocols are faced with the challenge of producing multi-hop routes and limitation of bandwidth. We compare the performance of two multicast routing protocols for mobile ad hoc networks - Serial Multiple Disjoint Tree Multicast Routing Protocol (Serial MDTMR) and Adaptive Core Multicast Routing Protocol (ACMRP). The simulator is implemented with GloMoSim.

• Fisheries and Aquatic Sciences
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• v.18 no.4
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• pp.387-393
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• 2015

Biotyping of Vibrio vulnificus strains isolated from marine environments along the south coast of Korea showed that the majority of the isolates (94.7%) belonged to biotype 1 and the remaining isolates (5.3%) belonged to biotype 2. Analysis of 16S rRNA V. vulnificus strains isolated from marine environments using a multiplex polymerase chain reaction (PCR) revealed that 78.7% were type A and 21.3% were type B. Random amplified polymorphic DNA (RAPD) was used to analyze the genomic differences in V. vulnificus among the biotype 2 strains isolated from marine environments (newly isolated strains group) and reference strains obtained from infected eels (reference strains group). The two groups had distinctly different profiles of the amplicons produced from RAPD. Additionally, biochemical comparison of these strains revealed that all four strains isolated from marine environments differed from the strains isolated from eels in their ability to promote D-mannitol fermentation. Two (NH 1 and NH 2) out of four isolates of biotype 2 from marine environments showed pathogenicity in eels Anguilla japonica in a challenge test. These isolates did not agglutinate with antisera against V. vulnificus NCIMB 2137 (serovar E), ATCC 27562 (non-serovar E), and ATCC 33816 (atypical serovar E).

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.4989-4992
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• 2013

Aim: To compare p16INK4a immunocytochemistry with the HPV polymerase chain reaction in predicting high grade cervical squamous intraepithelial lesions. Materials and Methods: This diagnostic case-control study was conducted from January 2010 until December 2010. We obtained 30 samples, classified according to the degree of cervical intraepithelial neoplasia (CIN): 11 samples for CIN 1, 9 samples for CIN 2, and 10 samples for CIN 3. HPV PCR, p16INK4a immunocytochemistry, and histopathological examination were performed on all samples. Statistical analysis was conducted using SPSS 20.0. Results: In predicting CIN 2-3, we found p16INK4a to have similar specificity and positive predictive value as HPV PCR (95%, 97.2% vs 96.7%), but better sensitivity (87.5% vs 72.5%) and negative predictive value (82.1% vs 67.6%). The most prevalent types of high-risk HPV in our study were HPV 33, 35, 58, 52, and 16. Conclusions: p16INK4a has better diagnostic values than HPV PCR and may be incorporated in the triage of ASCUS and LSIL to replace HPV PCR. Genotype distribution of HPV differs in each region, providing a challenge to develop HPV vaccines based on the epidemiology of HPV in that particular region.