• 대한예방한의학회지
• /
• 제2권1호
• /
• pp.1-11
• /
• 1998

This experimental study was carried out to evaluate the effort of Lulianwendang on number of white blood cells and blood platelets in anti-neoplastic agents treated mice. The results were as follows; 1. The group of adriamycine treated and Lulianwendang administered mice were increased significantly in WBC as compared with control group.: 2. The group of cyclophosphamide injected and Lulianwendang administered mice were increased significantly in WBC as compared with control group. 3. The group of vincristin injected and Lulianwendang administered mice were increased significantly in W5C as compared with control group. 4. The group of adriamycine treated and Lulianwendang administered mice were increased significantly in blood platelets as compared with control group. 5. The group of cyclophosphamide injected and Lulianwendang administered mice were increased significantly in blood platelets as compared with control group. 6. The group of vincristin injected and Lulianwendang administered mice were increased significantly in blood platelets as compared with control group. According to the results, we can suggest that Lulianwendang has the hematopoiesis effects against anti-neoplastic agents treated mice.

• 대한한방소아과학회지
• /
• 제19권1호
• /
• pp.67-82
• /
• 2005

Objectives : This study was conducted to find out the effect of Yukmijiwhangtanggamibang (YM) on growth, learning and memory of rats. Methods : It was divided SD rats into Sham group, 192 Saporin injection(SA+Saline) group and Injection of 192 Saporin with YM(SA+YM) group. Growth measure length of bone and tail. Memory performance was used aquisition test and learning retention of morris water maze. It was detected acetylcholinesterase(AChE), cholineacetyltransferase(ChAT) at medial septum and hippocampus by immunohistochemistry Results : Body Weight of the SA+YM Group increased effectively, as compared with SA Saline group. Growth of bone in the SA+YM Group increased effectively, as compared with SA+Saline group. Growth of Tail in the SA+YM Group increased effectively, as compared with SA_Saline group. The SA+YM Group in Aquisition Test improved effectively, as compared with SA+Saline group. The SA+YM Group in Learning Test improved effectively, as compared with SA+Saline group. The numbers of ChAT cells in Medial septum increased effectively, as compared with SA+Saline group. The numbers of ChAT cells in CA1 of Hippocampus increased, but was not effective. Conclusion : These results suggest that YM has an improving effect on the impaired learning through the effects on memory registration and retrieval.

• 혜화의학회지
• /
• 제13권1호
• /
• pp.81-88
• /
• 2004

As a long-term goal for the development of new prescriptions for hyperlipidemia, OBL was examined in the present study using a rat model in which the hyperlipidemia was induced. The major parameters related to lipid metabolism were investigated and the key findings are summarized below. 1. The body weight of hyperlipidemia-induced rats was increased by 50.6% compared to control group whereas the body weight of hyperlipidemia-induced rats with OBL injection showed 33.3% increases above the control group. 2. OBL-treated animals showed significant decreases in cholesterol levels compared to control group at the time point of 4 months after OBL injection. 3. OBL-treated animals showed significant decreases in T. cholesterol levels in comparison with the control group. 4. OBL-treated animals showed significant decreases in glucose levels compared to control group. 5. OBL-treated animal group showed decreases in SGOT and SGPT levels compared to control group, but its effects were not statistically significant. 6. Levels of HDL cholesterol were increased in OBL-treated animal group compared to the control, but the difference was statistically insignificant. 7. Levels of LDL cholesterol were decreased in OBL-treated animal group compared to the control group, but the difference was statistically insignificant.

• Applied Microscopy
• /
• 제43권2호
• /
• pp.54-64
• /
• 2013

The study examined the antioxidant activities and anti-inflammatory effects of rutin from the streptozotocin (STZ)-induced diabetic rats. Results revealed that the levels of plasma glucose and serum glucose were remarkably higher in the STZ-treated group compared to other groups and were significantly reduced in the STZ+rutin treated group compared to the STZ-treated group. In terms of weight, it significantly increased in all experimental groups during the experiment period except for STZ-induced diabetic group. The weight of the STZ-treated group was remarkably reduced compared to other groups. Regarding the weight of each body organ, the STZ-treated group showed higher organ weight compared to the other groups while STZ+rutin-treated group showed significantly reduced kidney and liver weights compared to those of STZ-treated group. In the pancreas tissue of the STZ-treated group, ${\beta}$-cell destruction and vacuolization were observed. Inflammation in the heart, liver, kidney, and retina tissues were also vividly recorded. In the STZ+rutin administered group, the heart and retina tissues were shown to be preserved normally while the liver and kidney tissues showed reduced histopathology in general compared to the STZ-treated group. Conclusionally, the rutin has the effect on the antioxidant activities and anti-inflammation in the STZ-induced diabetic rats.

• 대한본초학회지
• /
• 제20권2호
• /
• pp.171-179
• /
• 2005

Objectives & Methods : In order to evaluate the in vivo synergic effect of Mawhangyounpye-tang which was a traditional poly-herbal formula has been used in the treatment of respiratory diseases in Korea, with quinolone antibiotic, ciprofloxacin (CPFX), the viable bacterial number and histopathological changes were monitored after experimental respiratory infection with Klebsiella peumoniae NCTC 9632. Results : The obtained results were as follows : 1. In CPFX group, the viable bacterial numbers were significantly decreased compared to that of control group and these were more dramatically decreased compared to that of single treatment with CPFX, respectively in concomitant treated groups with Mawhangyounpye-tang. 2. In control group, severe infiltration of inflammatory cells, hemorrhage and hypertrophy of alveolar linings were demonstrated at microscopical levels. However, these abnormal histopathological changes were significantly decreased compared to that of control group in CPFX group, and these were more dramatically decreased compared to that of single treatment with CPFX, respectively in concomitant treated groups with Mawhangyounpye-tang. 3. In CPFX group, the LSA (luminal surface of alveoli %) were significantly increased compared to that of control group and these were more dramatically decreased compared to that of single treatment with CPFX, respectively in concomitant treated groups with Mawhangyounpye-tang. Conclusions : It is considered that in vivo antibacterial activity of CPFX was dramatically increased by concomitant use of Mawhangyounpye-tang against Kebsiella pneumoniae NCTC 9632 infection of respiratory tract.

• 대한한의학회지
• /
• 제17권1호
• /
• pp.146-170
• /
• 1996

This study aimed to evaluate the anti-stress effects of Walgukhwan, Walgukhwan+Ejintang and Wal gukhwan+Samultang. The experimental animals treated with each extracts during 15 days before the immobilization stress. And each experimental animals were endowed with 12 hours immobilization stress. Then the brain, blood and urine catecholamine contents and serum total cholesterol, triglyceride and free fatty acid levels were studied. The result were as followed; 1. Walgukhwan, Walgukhwan+Ejintang and Walgukhwan+Samultang were not statistically effective to the changes of the body weight. 2. Walgukhwan was statistically effective to the increase of the blood norepinephrine content as compared with control. 3. Walgukhwan+Ejintang was statistically effective to the increase of the blood and urine norepinephrine contents as compared with control. 4. Walgukhwan+Samultang was statisticallv effective to the increase of the brain, blood and urine norepinephrine contents and also to the increase of the blood and urine dopamine contents as compared with control. 5. Walgukhwan was statistically effective to the increase of the serum free fatty acid level as compared with control. 6. Walgukhwan+Ejintang was statistically effective to the increase of the serum triglyceride and free fatty acid levels as compared with control. 7. Walgukhwan+Samultang was statistically effective to the increase of the serum total cholesterol, triglyceride and free fatty acid levels as compared with control.

• Advances in environmental research
• /
• 제4권1호
• /
• pp.1-15
• /
• 2015

A pot experiment was conducted to assess the effects of red pepper (Capsicum annuum) and coriander (Coriandrum sativum) on seedling growth of wheat (Triticum aestivum). The aqueous extracts treatment of red pepper and coriander showed a significant (p < 0.05) reduction in root, shoot and seedling length, number of leaves and seedling dry weight of wheat (T. aestivum) as compared to control. The inhibitory different effect on growth of wheat (T. aestivum) was directly proportional to the increasing concentration (1, 2, 3, 4 and 5%) of aqueous extracts of red pepper and coriander as compared to control treatment (0%). The root, shoot, seedling length and number of leaves of T. aestivum significantly p < 0.05 decreased at 5% concentration of red pepper as compared to control. The root, shoot and seedling growth of T. aestivum was also significantly reduced at 1, 2, 3, 4 and 5% concentration of coriander as compared to control. The root, shoot and leaves dry weight of T. aestivum at 5% coriander extract treatment concentration decreased as compared to control. The tolerance in seedlings of T. aestivum to red pepper and coriander extract treatment was dose dependent as compared to control. The seedlings of T. aestivum showed low percentage of tolerance to pepper extract treatment than coriander extract treatment.

• 대한영양사협회학술지
• /
• 제19권4호
• /
• pp.389-399
• /
• 2013

This study compared the nutritional composition and antioxidative activity of different parts of Taraxacum coreanum (aerial parts and roots) according to different drying methods (natural drying and freeze-drying). There were no significant differences in vitamin C content in roots depending on the drying methods. However, vitamin A (P<0.01), E (P<0.001) and C (P<0.001) content of aerial parts, and vitamin A (P<0.001) and E (P<0.05) content of roots were significantly higher after freeze-drying compared to natural drying. For organic acids, the oxalic acid content of the aerial parts and roots were the highest. The total polyphenol and total flavonoid content in extracts from the aerial parts (P<0.01) and roots (P<0.05) were significantly higher after freeze-drying compared to natural drying. In addition, the total polyphenol and flavonoid content, DPPH radical scavenging activity, and antioxidative index from the natural drying and freeze-drying of Taraxacum coreanum extracts were significantly higher in the aerial parts compared to the roots (P<0.05). These results suggest that the nutritional composition and antioxidative activity of Taraxacum coreanum are higher in the aerial parts compared to the roots, and higher after freeze-drying compared to natural drying. Therefore, the aerial parts of Taraxacum coreanum could be suggested as an antioxidative functional food source.

• 소성∙가공
• /
• 제21권1호
• /
• pp.67-74
• /
• 2012

Although high productivity is possible, cold forged helical gears have not been widely used due to difficulty in achieving mechanical properties as well as dimensional accuracy of the product. Confidence in the gear characteristics also is very important in heavy-duty gear applications. Therefore, the properties of forged gears must be compared to the properties of conventional machined gears. The properties might be different due to the different fabrication processes. In this study, machined and forged products both before and after heat-treated have been compared by measuring the residual stress and involute curve of the tooth. Characteristics of hardness and microstructure were also compared. Additionally, tooth fracture strength was compared for the heat-treated products. Moreover, the tooth strength and the fracture pattern were compared between the machined and forged gears. The forged gear showed decreased changes in residual stress and decreased changes in dimensions when compared to the machined gear before and after heat treatment. The forged gear was over 10% better than the machined gear in tooth strength.

• 대한한방부인과학회지
• /
• 제21권4호
• /
• pp.128-138
• /
• 2008

Purpose: The purpose of this study was to compare the CBC and HRV of postpartum women in the early 30s. according to parity. Methods: This study was done on 107 postpartum women between 30 and 34 years who admitted for postpartum care in Oriental Hospital of Woosuk University from 3rd February 2008 to 19th September 2008. They took the test of CBC and HRV. The SPSS 12.0 for windows was used to analyze the data and the independent samples t-test were used to verify the results. Results: 1. WBC and Grn of primipara group significantly increased compared with that of multipara group. LYM of multipara group significantly increased compared with that of primipara group. 2. Mean-RR and Complexity of multipara group significantly increased compared with that of primipara group. Mean-HR of primipara group significantly increased compared with that of multipara group. 3. Ln (HF) and Normalized HF of multipara group significantly increased compared with that of primipara group. Normalized LF of primipara group significantly increased compared with that of multipara group. Conclusion: The findings suggest that activation of the sympathetic nervous system in primipara group is higher than in multipara group. and activation of the parasympathetic nervous system in primipara group is lower than in multipara group.