• BMB Reports
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• v.41 no.8
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• pp.597-603
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• 2008

Atopic dermatitis (AD) is a chronic inflammatory skin disease that induces changes in various inflammatory skin cells. The prevalence of AD is as high as 18% in some regions of the world, and is steadily rising. However, the pathophysiology of AD is poorly understood. To identify the proteins involved in AD pathogenesis, a comparative proteomic analysis of protein expression in peripheral blood mononuclear cells isolated from AD patients and healthy donors was conducted. Significant changes were observed in the expressions of fourteen proteins, including the vinculin, PITPNB, and Filamin A proteins. Among the proteins, $\alpha$-SNAP and FLNA decreased significantly, and PITPNB increased significantly in AD patients compared with control subjects; these findings were further confirmed by real-time PCR and Western blot analysis. The comparative proteome data may provide a valuable clue to further understand AD pathogenesis, and several differentially regulated proteins may be used as biomarkers for diagnosis and as target proteins for the development of novel drugs.

• Journal of Genetic Medicine
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• v.2 no.2
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• pp.71-77
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• 1998

Comparative genomic hybridization (CGH) can now be applied to detect the origin of extra or missing chromosomal material in cases with common unbalanced aberrations and in prenatal investigations. This method has been used in 13 cases of fetal samples for this study; 3 for amniocytes, 2 for cord blood and 8 for abortus tissues. These samples were previously subjected to GTG-banding. Our study showed aneuploidy in 8 cases, and partial monosomy, partial trisomy or marker chromosome in the remaining 5. The CGH disclosed further small genetic imbalances in 4 of all 13 cases: a prenatal sample showing del(20)(q13) by GTG confirmed a loss of the segment 20p13-pter by CGH; a marker chromosome manifested normal CGH profile; chromosome der(?)(?;15) found in an abortus sample by GTG turned out to be a loss of 15pter-q14 (partial monosomy) and a gain of 10pter-q22 (partial trisomy); the der(15) shown by GTG represented partial trisomy of 3q24-qter. These findings show that CGH is very useful and efficient for cytogenetic investigations of clinical cases.

• Korean Journal of Comparative Education
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• v.28 no.4
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• pp.137-163
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• 2018

Regarding professionalism of primary teachers, a dispute over professionalism as classroom teachers versus as subject teachers has been amplified past decades. However, these controversies tend to be resolved mainly by theocratical, political, and systematic facets. In other words, discussions on professionalism of primary teachers have been explored in various aspects, but they have not much focused on teacher preparation programmes. Moreover, although from a comparative educational point of view some research focus on teacher preparation programmes in North Americas and European countries, comparison studies of the programmes in East Asian countries, such as China, Japan and Korea have been rarely conducted. The aim of this study is to compare teacher preparation programmes between Korea and China, and based on what the research found we attempt to understand Korean programmes from a new perspective. Selecting each of 13 teacher educational universities in two countries, we analyse documentations of the universities in which the educational aims, proportions of curricula construction, curricula requirements, and types of subjects are presented. Our research offers implications for future revisions of teacher preparation programmes.

• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2004.05a
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• pp.83-83
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• 2004

• International Journal of Concrete Structures and Materials
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• v.5 no.2
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• pp.113-117
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• 2011

The purpose of this work is the comparative study for grinding of two cement clinkers. X-ray fluorescence, physical and granulometric tests and optical microscopy were used to characterize the clinkers. Also grinding tests were carried out for ten samples to determine the parameters influencing grindability of its clinkers. The results of calculation of the energies of grinding according to the law developed by Von Rittinger and the study of the microstructure of the two clinkers shows good agreements. Indeed, frequent clusters of belite which indicate a lack of uniformity and fineness have an effect on lowering the grindability. The obtained analyses and the results enabled us to interpret the granulometry and the microstructure of clinker to control quality and resistance.

• Journal of the Korean Operations Research and Management Science Society
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• v.11 no.1
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• pp.12-23
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• 1986

The minimum attractive rate of return (MARR) has been used for many years as a decision criterion in engineering economic analysis. Typically, inflation has been either ignored in such studies or considered by adjusting each of the individual cash flows associated with a project for inflation, frequently a lengthy process. This research investigates a new decision criterion for economic analysis, the comparative rate of return (CRR). The CRR is defined to be the minimum rate of return earned on uninflated cash flows of proposed expenditures is simplified, since the analysis can be performed on the uninflated cash flows. The research presents a derivation of the CRR and investigates its relationships to the MARR, inflation rate project cash flows and project life.

• Journal of Korea Technology Innovation Society
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• v.4 no.3
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• pp.275-290
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• 2001

The frameworks for evaluation of national R&D programs reflect their various political and administrative cultures(Gibbons & Georghiou, 1987), and the structure of national R&D system. In this research the core research questions are : what is god evaluation\ulcorner What is being evaluated, by whom, by which criteria, for whom and what purpose\ulcorner In order to examine these general aims and answer these questions, in detail several objectives can be proposed on the process of this research. In this research, the national R&D programs will be considered in terms of the interface between evaluation and the wider policy-making process. The programs for case study are the Alvey program(UK), the Advanced Technology Program (US) and the Framework program(EU) . One of the characteristics of these programs is the well established evaluation systems they have. From the comparative analysis, we can withdraw some useful implication for Korean evaluation practice for national R&D programs. Evaluation system is social process and the way in which it is organized is critical to its outcome.

• Journal of Plant Biotechnology
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• v.5 no.4
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• pp.197-200
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• 2003

Scalable Vector Graphics (SVG) has enabled a visually appealing, browser-based application for the display of Brassica sequences relative to Arabidopsis thaliana, and there are currently more than 70,000 B. napus Expressed Sequence Tags (ESTs) displayed. The client side of this browser is based on a Custom Graphical User Interface (CGUI) library which uses SVG, a new web graphics standard, to provide windowing functionality inside the web browser. This windowing functionality, combined with asynchronous data retrieval and client side rendering overcomes two of the key technology imposed drawbacks of current web based browsers: Fixed displays and frequent page reloads. The end result is an intuitive and enjoyable browsing experience. The browser is accessible online from the Brassica / Arabidopsis Genomics Initiative (http://brassica.agr.gc.ca). Inquiries about the browser should be directed to LewisCT@agr.gc.ca.

• International Journal of Aeronautical and Space Sciences
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• v.1 no.2
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• pp.68-74
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• 2000

A comparative wind tunnel testing of an airplane model was performed at the Korea Aerospace Research Institute Low Speed Wind tunnel(KARI LSWT). The model used for the comparative test was a seaplane model from the Glenn L. Martin Wind(GLM) Tunnel of University of Maryland, U.S.A. The 6-component external balance used in force and moment measurement is pyramidal type, which is a precision device that has strain gauge-type load cell inside of balance and the virtual center of the balance coincides with the tunnel centerline. Image method is adopted to eliminate the tare and interference of the model support, and to correct the flow angularity to the model also. Test results from KARI LSWT were compared with the results from GLM tunnel.

• Natural Product Sciences
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• v.21 no.3
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• pp.185-191
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• 2015

Comparative molecular analysis has been frequently adopted for the authentication of herbal medicines as well as the identification of botanical origins. Roots and rhizomes of the family Umbelliferae have been used as traditional herbal medicines to relieve various symptoms such as inflammation, neuralgia and paralysis in countries of East Asia. Since most herbal medicines of the Umbelliferae roots or rhizomes are generally supplied in the form of dried slices, morphological examination does not often provide sufficient evidence to identify the botanical origin. Using species-specific probes developed by the comparative analysis of nrDNA ITS sequences, a DNA chip was developed to identify herbal medicines for 13 species in the Umbelliferae. The developed DNA Chip proves its potential as a rapid, sensitive and effective tool for authenticating herbal medicines in future.