• Title/Summary/Keyword: Comparative Research

Search Result 6,467, Processing Time 0.032 seconds

Common plasma protein marker LCAT in aggressive human breast cancer and canine mammary tumor

  • Park, Hyoung-Min;Kim, HuiSu;Kim, Dong Wook;Yoon, Jong-Hyuk;Kim, Byung-Gyu;Cho, Je-Yoel
    • BMB Reports
    • /
    • v.53 no.12
    • /
    • pp.664-669
    • /
    • 2020
  • Breast cancer is one of the most frequently diagnosed cancers. Although biomarkers are continuously being discovered, few specific markers, rather than classification markers, representing the aggressiveness and invasiveness of breast cancer are known. In this study, we used samples from canine mammary tumors in a comparative approach. We subjected 36 fractions of both canine normal and mammary tumor plasmas to high-performance quantitative proteomics analysis. Among the identified proteins, LCAT was selectively expressed in mixed tumor samples. With further MRM and Western blot validation, we discovered that the LCAT protein is an indicator of aggressive mammary tumors, an advanced stage of cancer, possibly highly metastatic. Interestingly, we also found that LCAT is overexpressed in high-grade and lymph-node-positive breast cancer in silico data. We also demonstrated that LCAT is highly expressed in the sera of advanced-stage human breast cancers within the same classification. In conclusion, we identified a possible common plasma protein biomarker, LCAT, that is highly expressed in aggressive human breast cancer and canine mammary tumor.

Recent Research Trends and Prospects of HR Analytics in Korea (HR 애널리틱스의 최근 연구 동향 및 향후 과제)

  • Jo, Hui-Jin;Ahn, Ji-Young
    • The Journal of the Korea Contents Association
    • /
    • v.22 no.3
    • /
    • pp.442-452
    • /
    • 2022
  • This study was conducted to understand research trends of HR Analytics (HRA) in Korea and to suggest future research directions. First, a comparative analysis was conducted by classifying six areas of recruitment on-board, work environment, performance evaluation, retention, and exit/retirement building on the employee life cycle framework. The results indicate that first, the distribution of detailed research topics in Korean HRA research has similar to that of international research. Second, Korean HRA studies related to employee training and development function are insufficient. Third, the scope and the method of machine learning are becoming enriched. Finally Korean HRA studies are still in the technical domain and toward entering the predictive analysis domain.

A Comparative Study on the Functional Compounds of Color Potatoes

  • Jung Hwan Nam;Ki Deog Kim;Jong Taek Suh;Jong Nam Lee;Su Jeong Kim;Hwang Bae Sohn
    • Proceedings of the Plant Resources Society of Korea Conference
    • /
    • 2021.04a
    • /
    • pp.47-47
    • /
    • 2021
  • This study was carried out to obtain a basic information for the improvement of human health and the development of variety through analysis of organic compounds, contents of three CQA(3-caffeoylquinic acid, 4-caffeoylquinic acid and 5-caffeoylquinic acid) and five anthocyanin (petunidin-3-p-cumaroylrutinoside-5-glucoside, pelargonidin-3-p-cumaroylrutin-oside-5-glucoside, peonidin-3-p-cumaroylrutinoside-5-glucoside, pelargonidin-3-p-feruloyl-rutinoside-5-glucoside and peonidin-3-feruloylrutinoside-5-glucoside)to color potatoes is Hong-young(HY) and Ja-young(JY). The analytical results on organic compounds in color potatoes were shown as follow, The contents of CQA and Anthocyanin of JY variety were shown to be higher than HY, while CQA and Anthocyanin were appeared to be highest in peel of JY. Overall, JY had higher amount of physicochemical properties than HY. The results of this study reveal the quantitative analysis of functional compounds seperated from various kind of potatoes, which will enable the acquisition of new bioactive candidates and the establishment of new profit generation models for farmers.

  • PDF

A Study of Dress Characteristics with Respect to Anti-Social Resisting Consciousness - Focus on the Relationship between 18th Century Sans-Culotte and a Hippy Style During the 1960s and 1970s as a Comparative Perspective - (반사회적 의식이 반영된 시대복식의 특성에 관한 연구 - 18세기 상-뀔로뜨와 1960, 70년대 히피 스타일의 비교를 중심으로 -)

  • Jun, Yuh-Sun;Kim, Young-Sam
    • Journal of the Korean Society of Costume
    • /
    • v.62 no.6
    • /
    • pp.112-126
    • /
    • 2012
  • The style of a dress allows important characterization of an era since they reflect contemporary politics, society, culture and arts. Within a same category, period costumes develop into styles that reflect specific consciousness. The research method and the scope of the study are as follows: the research adopts a historical study method and a comparative research from a microscopic point. The scope includes resistance costumes that proceed with sans-culotte that comprises of the resistance party during the 18th French Revolution (1783-1799), and also a Hippy style which was popularized during the 1960s and 1970s for its anti-war movement. We researched both similarities and differences of design factors reflecting resisting consciousness in costumes that affected costume characteristics related to their socio-cultural background. Sans-culotte and the Hippie style reflect a common denominator in anti-social resisting customs. First, they show common characteristics that combine fashion trends of resistant element and design features. Second, they have common features which are the characteristics of deviation. On the other hand, these two customs also present a discriminative denominator in anti-social resisting customs. In the case of sans-culotte, they tend to symbolize confrontation by dividing into two equal parts: the old and new mode. Sans-culotte confronts the conventional mode and promotes practical costume styles based on justice standpoints. First, hippies pursue an exposition of individual emotions that disclose internal meanings of love and desire. Second, they focus on subjective characteristics and chase after masteries and pleasures by expressing intensity. Third, it extends and develops folk costumes from many countries that reveal ethnic trends. Therefore, this research compares and contrasts different changes in the fashions of revolutionary periods, and aims to recognize the relationship between design and costume characteristics, thus contributing to the predictions of future changes in fashion.

Medical costs for patients with Facial paralysis : Based on Health Big Data (보건의료 빅데이터를 이용한 얼굴마비환자의 의료비용에 관한 연구)

  • Hong, Min-Jung;Umh, Tae-Woong;Kim, Sina;Kim, Nam-Kwen
    • The Journal of Korean Medicine
    • /
    • v.36 no.3
    • /
    • pp.98-110
    • /
    • 2015
  • Objectives: The purpose of this study was to analyze the medical cost of facial paralysis in payer perspective and to estimate the practice pattern of patient using 2011 Health Insurance Review & Assessment Service-National Patients Sample(HIRA-NPS). Methods: Basic statistical system was used for descriptive analysis of NPS dataset. A table for general information (table20) was extracted by disease code, and social demographic characteristics, distribution of the use among inpatients and outpatients, utilization of each kind of medical care institutions, medical cost were analyzed. Subgroup analysis was conducted for assuming the practice pattern of korean medicine and western medicine. Results: A total of 8,219 people and 64,345 claims data were identified as having facial paralysis. Proportion of outpatient was 95.23%, inpatient 0.84% and patient using both services 3.93%. Mean patient charges was 44,229 won per outpatient, 178,886 won per inpatient and 523,542 won per patient using both services. Utilization of korean medical care institutions was 68.81%(claims), 40.46%(patients), utilization of western medical care institutions was 31.19%(claims), 59.54%(patients). The amount charged by korean medical care institutions was 52.61% and western medical care institutions was 47.39%. Cost per claim was higher than those of the korean treatment and cost per patient of western treatment was lower than those of the korean treatment. Conclusions: The research assessed the medical cost and practice pattern associated with facial paralysis. These findings could be used in health care policy and subsequent studies.

The Effect on Method of the Teaching & Learning Home Economics by the use of VTR on Making Korean Man’s Slacks (‘남자한복바지만들기’에 VTR을 활용한 가정과 교수.학습의 효과)

  • 이정희;윤인경
    • Journal of Korean Home Economics Education Association
    • /
    • v.4 no.1
    • /
    • pp.87-95
    • /
    • 1992
  • The purpose of this study is to suggest how we can get over the difficulties of practical drill under experimentation concerning the units of making clothes in the curriculum of home economics. The import of this study was based on the results of the preceding studies the field of the making Korean clothes, from the standpoint of the teaching tools and teaching materials by the use of VTR, is one of the most insufficient. On the one hand, the teaching procedure here a VTR, running 34 minutes or so, was made up with the process of making Korean men’s slacks, and was led by the researcher’s own. The contents of the lesson are as follows: the shape of Korean clothes, the name of each part, the process of drawing, cutting and sewing, and the items of evaluation and arrangement. On the other hand, the two comparative groups were made to compare one with the other: One group was taught by help of VTR media, and the other by the model performance and explanation of the instructor’s own. All of the statistical data were analyzed in terms of SPSS/PC, and t-verification was made, to make difference between the two, after standard deviation was calculated according to the classified domains. The consequences of the test research are shown as below: 1. The difference of understanding was obviously made in considering that the group made a better score than the comparative one in understanding to process of making Korean clothes. 2. The difference of skill was highly made in considering that the group made a better score than the comparative one in the practical drill of making Korean clothes. 3. The difference of interests was evidentally made in considering that the group made a better score than the comparative one in the stage of making Koran clothes. Such means that the motivation and attitude of the learners was made stimulate by the Audio-Visual material than by the traditional cramming method. 4. The difference of frequency was fairly made in considering that the experimeatal group made a better score than the comparative one in the frequency of individual teaching. 5. The difference of the efficiency of time-consumption was clearly made in considering that the experimental group made a better score than the comparative one. As the results of the research above, the medium of VTR proved to more effective to the achievement of schoolwork and the strategies of teaching. Therefore, more use of VTR media will help the instructors with the difficulties of practical drill in the whole process of making Korean clothes; Widely use of VTR media in teaching will be surely more fruitfull to the unit of making Korean clothes than teaching by explanation.

  • PDF

A Study on the Functional Sleeve Pattern of Sports Climbing Wear (스포츠 클라이밍 웨어의 기능성 소매패턴 연구)

  • Im, Ga Bin;Park, Ju Hee
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.41 no.4
    • /
    • pp.585-598
    • /
    • 2017
  • Sports climbing requires more maximum body motion range than any other sport. This study examined what element affects the actions of sports climbers and suggest an ideal pattern archetype to maximize function based on motion. The theoretical background included abstracted elements influencing clothing design by researching the body type of sports climbers and the motion of sports climbing. Along with the characteristic of climbing wear, this study also conducted a comparative analysis of sleeve patterns for sports climbing wear and general sports jackets, abstracting comparative parts that influence sports climbing wear design. To develop the final research archetype, research was done on 107 sports climbers in their 20s-30s that selected the top 3 brands and collected patterns as well. A research archetype was selected based on 3-D virtual clothing and developed into 4 different patterns with different sleeve cap heights. Appearance evaluation and a motion functionality evaluation were then conducted in order to select a final research archetype adequate for sports climbing based on evaluation findings. In addition, this study identified aesthetical problems of the final research archetype produced based on functionality that could suggest an archetype for a climbing jacket that could be visually satisfying through appearance evaluations and motion functionality evaluations.

A comparative analysis on research trends of statistics education between Korea and overseas (국내외 통계교육 연구동향 비교 분석)

  • Lee, Eun Hee;Kim, Won Kyung
    • The Mathematical Education
    • /
    • v.54 no.3
    • /
    • pp.241-259
    • /
    • 2015
  • The purpose of this study is to analyze research trends and specific features in the statistics education between Korea and overseas. For this purpose, a total of 180 articles presented in 4 domestic and 4 foreign journals of the mathematics education and statistics education was investigated. The result findings are as follows. First, more than half of researches have been carried out in teaching and learning, understanding of statistical concepts in both of domestic and foreign journals. Second, some researches on the affective effect were carried out in foreign journals, but not in domestic journals. Third, researches on the teacher education were carried out mainly for the pre-service teachers in domestic journals, but mainly for the in-service teachers in foreign journals. Fourth, empirical study was mainly used for the research method in domestic journals while both empirical and non-empirical study were used in foreign journals. Fifth, subjects of research were mainly secondary students in domestic journals, but over undergraduate students in foreign journals.

Development of Comparative Verification System for Reliability Evaluation of Distribution Line Load Prediction Model (배전 선로 부하예측 모델의 신뢰성 평가를 위한 비교 검증 시스템)

  • Lee, Haesung;Lee, Byung-Sung;Moon, Sang-Keun;Kim, Junhyuk;Lee, Hyeseon
    • KEPCO Journal on Electric Power and Energy
    • /
    • v.7 no.1
    • /
    • pp.115-123
    • /
    • 2021
  • Through machine learning-based load prediction, it is possible to prevent excessive power generation or unnecessary economic investment by estimating the appropriate amount of facility investment in consideration of the load that will increase in the future or providing basic data for policy establishment to distribute the maximum load. However, in order to secure the reliability of the developed load prediction model in the field, the performance comparison verification between the distribution line load prediction models must be preceded, but a comparative performance verification system between the distribution line load prediction models has not yet been established. As a result, it is not possible to accurately determine the performance excellence of the load prediction model because it is not possible to easily determine the likelihood between the load prediction models. In this paper, we developed a reliability verification system for load prediction models including a method of comparing and verifying the performance reliability between machine learning-based load prediction models that were not previously considered, verification process, and verification result visualization methods. Through the developed load prediction model reliability verification system, the objectivity of the load prediction model performance verification can be improved, and the field application utilization of an excellent load prediction model can be increased.

A Review on The Comparative Study on Temperament And Character Inventory (TCI) And Constitutional-psychological Questionnaire (Temperament and Character Inventory(TCI)와 심리(心理)관련설문지의 비교연구에 대한 고찰(考察))

  • Kang, Dong-Woo;Oh, Hwan-Sup;Park, Young-Jae;Park, Young-Bae
    • The Journal of the Society of Korean Medicine Diagnostics
    • /
    • v.15 no.1
    • /
    • pp.29-46
    • /
    • 2011
  • Objectives: The purpose of our study is to develop and verify questionnaire using temperament and character inventory (TCI) in the future by contemplating the comparative study on TCI and psychological testing Questionnaires. Methods: We investigate the research searched by keyword: 'TCI' and 'Questionnaire' through internet search engines, Pub Med, Science Direct and Springer Link. Results: The comparative study of TCI and psychological testing Questionnaires(SPAQ, BDI, TAS-20, MAC, DSQ) which have the purpose of diagnosing personal disorder is helpful for the verification of the level of adequacy of the concerned psychological testing Questionnaire and contributes to the understanding of psychobiological characteristics of each of personal disorders. The comparative study of TCI and psychological testing Questionnaires(MMPI, NEO, CPI) which have the purpose of comprehending general personality is helpful for the verification of the level of adequacy of the concerned psychological testing Questionnaire and contributes to the understanding of meaning of questionnaire-scales. The comparative study of TCI and constitution-psychological testing Questionnaire(QSCC II) is helpful for the verification of the level of adequacy and the understanding of the concerned constitution-psychological testing Questionnaire and contributes to the understanding of psychobiological characteristics of each of constitutions. Conclusions: TCI is a useful tool to understand the psychological testing Questionnaire more deeply and verify the level of the adequacy, and from now on for the development and verification of Oriental medicinal-psychological testing Questionnaire, the study comparing it with TCI should be actively used.