• Genomics & Informatics
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• 제19권4호
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• pp.49.1-49.11
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• 2021

Nowadays, Genomic data constitutes one of the fastest growing datasets in the world. As of 2025, it is supposed to become the fourth largest source of Big Data, and thus mandating adequate high-performance computing (HPC) platform for processing. With the latest unprecedented and unpredictable mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the research community is in crucial need for ICT tools to process SARS-CoV-2 RNA data, e.g., by classifying it (i.e., clustering) and thus assisting in tracking virus mutations and predict future ones. In this paper, we are presenting an HPC-based SARS-CoV-2 RNAs clustering tool. We are adopting a data science approach, from data collection, through analysis, to visualization. In the analysis step, we present how our clustering approach leverages on HPC and the longest common subsequence (LCS) algorithm. The approach uses the Hadoop MapReduce programming paradigm and adapts the LCS algorithm in order to efficiently compute the length of the LCS for each pair of SARS-CoV-2 RNA sequences. The latter are extracted from the U.S. National Center for Biotechnology Information (NCBI) Virus repository. The computed LCS lengths are used to measure the dissimilarities between RNA sequences in order to work out existing clusters. In addition to that, we present a comparative study of the LCS algorithm performance based on variable workloads and different numbers of Hadoop worker nodes.

• 인간식물환경학회지
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• 제24권6호
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• pp.663-672
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• 2021

Background and objective: As the 'Healing Agriculture Research and Development and Promotion Act' came into effect on March 25, 2021, social interest in agro-healing has been increasing exponentially. This study was conducted to analyze the priorities of agro-healing classification system and to provide basic data to inform policy directions and related research for the development and activation of agro-healing. Methods: The survey data collected from 18 experts were analyzed using the analytic hierarchy process (AHP) method in determine the relative weights of the main and sub-criteria for the classification system. There were three main criteria identified: agro-healing input industry, agro-healing service industry, and agro-healing-related/derived industry. There were also 11 sub-criteria. Results: The top three sub-criteria with the highest complex weights include "community service," "social rehabilitation" and "treatment and rehabilitation," all of which correspond to the main criterion "agro-healing service industry". In addition, the complex weights of the sub-criteria corresponding to the main criterion "agro-healing related/derived industry" are as follows: "other agro-healing support service," which ranked 4th, and "training and education institutions for agro-healing experts," which ranked 5th when prioritizing the criteria. Conclusion: The results of this study suggest that the main criterion to be considered first in establishing a classification system is "agro-healing service industry". Therefore, it is necessary to continue research on detailed service classifications and systems with verified validity to ensure expertise in human resources, and organization related to social purpose services in agro-healing.

• Clinical and Experimental Reproductive Medicine
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• 제49권1호
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• pp.33-39
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• 2022

Objective: Male genital tract infections have been associated with infertility, and Escherichia coli has drawn increasing attention as an important bacterium in this context. This investigation aimed to characterize and compare the distributions of O-antigen serogroups of E. coli in the semen samples of fertile and infertile men. Methods: In this case-control study, semen samples were collected from 618 fertile and 1,535 infertile men. The E. coli-positive samples were evaluated in terms of concentration, morphology, viability, and motility parameters according to the World Health Organization 2010 guidelines. Finally, different serogroups of E. coli were identified by multiplex polymerase chain reaction targeting the O-antigen variations of the bacterium. Results: The prevalence of E. coli among fertile men was significantly higher than among infertile men (p<0.001). The sperm morphology, viability, and motility in the E. coli-positive fertile group were significantly higher than in the E. coli-positive infertile group (p<0.001). E. coli O6 was the most prevalent serogroup found in both groups. However, there was no significant difference in the frequency of different serogroups of E. coil between the two groups (p=0.55). Conclusion: Despite the higher prevalence of E. coli among fertile men, E. coli had more detrimental effects on semen parameters in infertile men. There was no significant difference in E. coli serogroups between the fertile and infertile groups.

• 대한간호학회지
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• 제53권4호
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• pp.426-438
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• 2023

Purpose: Walking practice is a representative indicator of the level of physical activity of local residents. Although the world health organization addressed reduction in prevalence of insufficient physical activity as a global target, the rate of walking practice in Korea has not improved and there are large regional disparities. Therefore, this study aimed to explore the spatial variations of walking practice and its associated factors in Korea. Methods: A secondary analysis was conducted using Community Health Outcome and Health Determinants Database 1.3 from Korea Centers for Disease Control and Prevention. A total of 229 districts was included in the analysis. We compared the ordinary least squares (OLS) and the geographically weighted regression (GWR) to explore the associated factors of walking practice. MGWR 2.2.1 software was used to explore the spatial distribution of walking practice and modeling the GWR. Results: Walking practice had spatial variations across the country. The results showed that the GWR model had better accommodation of spatial autocorrelation than the OLS model. The GWR results indicated that different predictors of walking practice across regions of Korea. Conclusion: The findings of this study may provide insight to nursing researchers, health professionals, and policy makers in planning health programs to promote walking practices in their respective communities.

• 현장농수산연구지
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• 제15권1호
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• pp.3-15
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• 2013

The purpose of this study is to investigate priority of cultural-environmental resource using the Analytic Hierarchy Process. Based on survey of expertise, a series of pairwise comparison judgements is performed to evaluate the relative strength or intensity of impact among the elements in the Hierarchy. This Study are applied three kinds of evaluation criteria and 40 kinds of cultural environmental resource. The results of this study are as follows. First, Traditional culture, landscapes, rural community vitality of Agriculture and Rural culture of environmental resources by establishing the concept of a comprehensive classification scheme are defined by the United Nations Food and Agriculture Organization (FAO) and the Rural Amenity Resources Multifunctionality in Agriculture. Second, Experts was considered important to "Continuity of history (43%),"> "Global importance (37%)"> "Notable characteristic (20%)" the order of the ratings on the importance of culture with rural agricultural and environmental resources. This is deemed the most important part of Continuity of history Third, The importance of the cultural and environmental resources comprehensive evaluation of the results, a strong tradition of building traditional sense or a landscape resource most highly were evaluated. and Vinyl greenhouse and warehouse such as agriculture, the current facilities required the relatively compared to other resources very low importance were evaluated. Resources, the importance of this study is judged to be able to be utilized as basic data in the selection criteria for the evaluation of the agricultural heritage.

• 동의생리병리학회지
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• 제36권5호
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• pp.155-162
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• 2022

Even after testing negative for COVID-19, some patients continue to struggle with a variety of symptoms such as fatigue, shortness of breath, gastrointestinal problems and neurological problems. The World Health Organization (WHO) defined long COVID (Post COVID-19 conditions) as "A disease occurs in individuals with a history of probable or confirmed SARS-CoV-2 infection, usually 3 months from the onset of COVID-19 with symptoms that last for at least 2 months, that cannot be explained by an alternative diagnosis." As a possible pathological mechanism of long COVID, three hypotheses are proposed: the persistence of the infectious state due to the residual virus, the persistent inflammatory response, and the autoimmune response. The main symptoms of long COVID are shortness of breath (dyspnea), abdominal pain and dyspepsia, fatigue, cognitive problems (brain fog), anosmia and dysgeusia, and chest pain, palpitations and tachycardia. In the Chinese guidelines, COVID-19 patients were divided into mild, moderate, severe, and recovery, and prescriptions with effective therapeutic effects were summarized to encourage combined treatment of chinese and western medicine. Globally, only symptomatic therapy is recommended for long COVID, but a specific treatment has not yet been proposed. Recently, morbidity code for post COVID-19 conditions was created, and it is planned to announce guidelines for long COVID treatment and management in the first half of 2023. In line with this trend, the Korean medical community needs to make efforts to prepare treatment guidelines for patients with long COVID.

• 한국전문물리치료학회지
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• 제30권2호
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• pp.136-143
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• 2023

Background: The International Classification of Functioning, Disability and Health (ICF) model, created by the World Health Organization, provides a theoretical framework that can be applied in the diagnosis and treatment of various disorders. Objects: Our research purposed to ascertain the relationship between structure/function, activity, and participation domain variables of the ICF and pain, pain-associated disability, activities of daily living (ADL), and quality of life in patients with chronic low back pain (LBP). Methods: Two-hundred patients with chronic LBP (mean age: 35.5 ± 8.8 years, females, n = 40) were recruited from hospital and community settings. We evaluated the body structure/function domain variable using the Numeric Pain Rating Scale (NPRS) and Roland-Morris disability (RMD) questionnaire. To evaluate the activity domain variable, we used the Oswestry Disability Index (ODI) and Quebec Back Pain Disability Scale (QBDS). For clinical outcome measures, we used Short-form 12 (SF-12). Pearson's correlation coefficient was used to ascertain the relationships among the variables (p < 0.05). All the participants with LBP received 30 minutes of conventional physical therapy 3 days/week for 4 weeks. Results: There were significant correlations between the body structure/function domain (NPRS and RMD questionnaire), activity domain (ODI and QBDS), and participation domain variables (SF-12), rending from pre-intervention (r = -0.723 to 0.783) and postintervention (r = -0.742 to 0.757, p < 0.05). Conclusion: The identification of a significant difference between these domain variables point to important relationships between pain, disability, performance of ADL, and quality in participants with LBP.

• 의학교육논단
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• 제25권2호
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• pp.132-138
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• 2023

Cohorts are established and operated at medical schools as part of efforts to improve the quality of education. Chosun University College of Medicine clarified the purpose of establishing three cohorts in light of its core values and developed criteria and indicators for each purpose. An organization focusing on cohort construction and operation was established as the Cohort Committee under the Quality Improvement Committee, and guidelines were proposed. In addition, a database and system were developed to handle primary data efficiently, and tools for measuring psychological variables were created. The data collected by establishing a cohort, regions, and admission types of graduates were first analyzed for the following projects: (1) an analysis of the educational process and quality improvement to educate medical professionals who contribute to the community after graduation, and (2) an analysis of the educational process and quality improvement to secure excellence in the medical field (e.g., knowledge and clinical reasoning), using information on the academic achievements of students and graduates as primary data. Chosun University College of Medicine is conducting cohorts and longitudinal studies gradually, starting with a simple, practically feasible system to solve the difficulties faced in cohort establishment and operation. Medical educators hope that future data collection and analysis will improve the quality of medical school education and have practical implications.

• 대한간호학회지
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• 제53권3호
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• pp.324-339
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• 2023

Purpose: This study aimed to valuate the reliability and validity of the Korean version of the 5C Psychological Antecedents of Vaccination (K-5C) scale. Methods: The English version of the 5C scale was translated into Korean, following the World Health Organization guidelines. Data were collected from 316 community-dwelling adults. Content validity was evaluated using the content validity index, while construct validity was evaluated through confirmatory factor analysis. Convergent validity was examined by assessing the correlation with vaccination attitude, and concurrent validity was evaluated by examining the association with coronavirus disease 2019 (COVID-19) vaccination status. Internal consistency and test-retest reliability were also evaluated. Results: Content validity results indicated an item-level content validity index ranging from .83 to 1, and scale-level content validity index, averaging method was .95. Confirmatory factor analysis supported the fit of the measurement model, comprising a five-factor structure with a 15-item questionnaire (RMSEA = .05, SRMR = .05, CFI = .97, TLI = .96). Convergent validity was acceptable with a significant correlation between each sub-scale of the 5C scale and vaccination attitude. In concurrent validity evaluation, confidence, constraints, and collective responsibility of the 5C scale were significant independent predictors of the current COVID-19 vaccination status. Cronbach's alpha for each subscale ranged from .78 to .88, and the intraclass correlation coefficient for each subscale ranged from .67 to .89. Conclusion: The Korean version of the 5C scale is a valid and reliable tool to assess the psychological antecedents of vaccination among Korean adults.

• 문화기술의 융합
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• 제9권4호
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• pp.509-515
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• 2023

현대 정부의 기능확대 추세에 따라 정부의 활동이나 운영이 증가하고 있는 상태에서 부정이나 낭비 요소 등 문제도 함께 발생하고 있다. 이에 각국은 이러한 문제를 해결하기 위해 내부통제기구를 구성하고 이를 발전시키고 있다. 이런 과정에서 미국의 감찰관 제도는 정부와 의회의 견제와 균형이라는 취지에서 출발하여 40년을 넘게 운영해오고 있다. 이에 따라 본 연구에서는 미국 연방정부가 운영하고 있는 내부통제 제도 중 하나인 감찰관 제도의 발전과정, 감찰관 공동체의 구성, 감찰관의 배치 및 협조, 이들의 감독 운영방안을 상세히 분석하였다. 이에 국내 정부기관의 내부통제시스템에서도 이와 유사한 제도의 도입과 운영을 위해서는 정부와 의회의 관계가 상호 존중과 견제와 균형의 체계를 유지하고, 이에 대한 학계와 관련 기관의 지속적인 연구가 필요하다.