• The Korean Journal of Pain
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• v.21 no.1
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• pp.11-17
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• 2008

Background: Peripheral nerve injury induces up-regulation of the calcium channel alpha2delta (${\alpha}2{\delta}$) subunit and TRPM8 in the dorsal root ganglion (DRG) which might contribute to allodynia development. We investigated the expression of the ${\alpha}2{\delta}$ subunit and TRPM8 in the DRG of sympathetically maintained pain (SMP) and sympathetic independent pain (SIP) rat model. Methods: For the SMP model, the L5 and L6 spinal nerves were ligated tightly distal to the DRG. For the SIP model, the tibial and sural nerves were transected, while the common peroneal nerve was spared. After a 7 day postoperative period, tactile and cold allodynia were assessed using von Frey filaments and acetone drops, respectively. Expression of the ${\alpha}2{\delta}$ subunit and TRPM8 in the L5 and L6 DRG were subsequently examined by a Western blot. Results: There were no significant differences between the two models for the thresholds of tactile and cold allodynia. Expression of the ${\alpha}2{\delta}$ subunit in the ipsilateral DRG to the injury was increased as determined on a Western blot as compared to that in the contralateral or sham-operated DRG of the SMP model, but there was no difference in expression seen with the use of the SIP model. There was no difference in the expression of TRPM8 in the ipsilateral DRG to the injury and the contralateral or sham-operated DRG of either model. Conclusions: Up-regulation of the ${\alpha}2{\delta}$ subunit in injured DRG may play a role that contributes to tactile allodynia development in SMP, but not TRPM8 to cold allodynia after peripheral nerve injury.

• Journal of Advanced Navigation Technology
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• v.19 no.5
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• pp.423-432
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• 2015

This paper shows that design, manufacture and the performance of FC-NIC (fibre channel network interface card) for network unit configuration which is based on one of the 5 main configuration items of the common functional module for IMA (integrated modular Avionics) architecture. Especially, FC-NIC uses zynq SoC (system on chip) for host load reductions. The host merely transmit FC destination address, source memory location and size information to the FC-NIC. After then the FC-NIC read the host memory via DMA (direct memory access). FC upper layer protocol and sequence process at local processor and programmable logic of FC-NIC zynq SoC. It enables to free from host load for external communication. The performance of FC-NIC shows average 5.47 us low end-to-end latency at 2.125 Gbps line speed. It represent that FC-NIC is one of good candidate network for IMA.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.31 no.6
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• pp.450-457
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• 2019

Sedimentation is a common problem for river ports. But its intensity depends on the rate of sedimentation, channel shape and size, hydrodynamic behavior of the river and the importance of the port. High sedimentation rate in Yangon River has become one major issue for Myanmar as her largest port is located on the Yangon riverbank. As a result of the high sedimentation rate, shallow water area near the confluence of Yangon River, Pazundaung Creek, and Bago River keeps blocking the navigation channel to the Yangon Port, which also limits the size of vessel calling to Yangon Port. Therefore, studies to understand sediment transport process in Yangon River are required because the economic development of Myanmar highly relies on the Yangon Port. This paper aims to calculate the sediment transport and to predict the riverbed elevation changes in Yangon River by using Bagnold (1966) theory. Calculation result shows that huge difference can be found in the bed load transport between the rainy season and dry season in Yangon River, and thus the sedimentation problem would become more severe in the dry season when the transported sediments are reduced. The estimated sedimentation rate in dry season indicates that the rate of riverbed level rise near the Yangon Port area is about 0.063 m per year, which would lead to approximately 3.15 m rise in the riverbed level in next 50 yrs, considering the same workload of dredging to maintain the navigation channel.

• The Korean Journal of Physiology and Pharmacology
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• v.20 no.1
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• pp.25-33
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• 2016

Ion channels in carcinoma and their roles in cell proliferation are drawing attention. Intracellular $Ca^{2+}$ ($[Ca^{2+}]_i$)-dependent signaling affects the fate of cancer cells. Here we investigate the role of $Ca^{2+}$-activated $K^+$ channel (SK4) in head and neck squamous cell carcinoma cells (HNSCCs) of dif-ferent cell lines; SNU-1076, OSC-19 and HN5. Treatment with $1{\mu}M$ ionomycin induced cell death in all the three cell lines. Whole-cell patch clamp study suggested common expressions of $Ca^{2+}$-activated $Cl^-$ channels (Ano-1) and $Ca^{2+}$-activated nonselective cation channels (CAN). 1-EBIO, an activator of SK4, induced outward $K^+$ current (ISK4) in SNU-1076 and OSC-19. In HN5, ISK4 was not observed or negligible. The 1-EBIO-induced current was abolished by TRAM-34, a selective SK4 blocker. Interestingly, the ionomycin-induced cell death was effectively prevented by 1-EBIO in SNU-1076 and OSC-19, and the rescue effect was annihilated by combined TRAM-34. Con-sistent with the lower level of ISK4, the rescue by 1-EBIO was least effective in HN5. The results newly demonstrate the role of SK4 in the fate of HNSCCs under the $Ca^{2+}$ overloaded condition. Pharmacological modulation of SK4 might provide an intriguing novel tool for the anti-cancer strategy in HNSCC.

• Journal of the Optical Society of Korea
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• v.15 no.2
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• pp.174-181
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• 2011

An airborne sensor is developed for remote sensing on an aerial vehicle (UV). The sensor is an optical payload for an eletro-optical/infrared (EO/IR) dual band camera that combines visible and IR imaging capabilities in a compact and lightweight package. It adopts a Ritchey-Chr$\'{e}$tien telescope for the common front end optics with several relay optics that divide and deliver EO and IR bands to a charge-coupled-device (CCD) and an IR detector, respectively. The EO/IR camera for dual bands is mounted on a two-axis gimbal that provides stabilized imaging and precision pointing in both the along and cross-track directions. We first investigate the mechanical deformations, displacements and stress of the EO/IR camera through finite element analysis (FEA) for five cases: three gravitational effects and two thermal conditions. For investigating gravitational effects, one gravitational acceleration (1 g) is given along each of the +x, +y and +z directions. The two thermal conditions are the overall temperature change to $30^{\circ}C$ from $20^{\circ}C$ and the temperature gradient across the primary mirror pupil from $-5^{\circ}C$ to $+5^{\circ}C$. Optical performance, represented by the modulation transfer function (MTF), is then predicted by integrating the FEA results into optics design/analysis software. This analysis shows the IR channel can sustain imaging performance as good as designed, i.e., MTF 38% at 13 line-pairs-per-mm (lpm), with refocus capability. Similarly, the EO channel can keep the designed performance (MTF 73% at 27.3 lpm) except in the case of the overall temperature change, in which the EO channel experiences slight performance degradation (MTF 16% drop) for $20^{\circ}C$ overall temperate change.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.1
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• pp.91-99
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• 2018

This paper has proposed a low-noise and high-linear RF receiver supporting TV white space from 470 MHz to 698 MHz), which is implemented in $0.13-{\mu}m$ CMOS technology. It consists of a low-noise amplifier, a RF band-pass filter, a RF amplifier, a passive down-conversion mixer, and a channel-selection low-pass filter. A low-noise amplifier and RF amplifier provide a high voltage gain to improve the sensitivity level. To suppress strong and nearby interferers, two RF filtering schemes have been performed by using a RF BPF and a down-conversion mixer. The proposed LPF has been based on the common-gate topology and adopted a bi-quad cell to achieve -24dB/oct characteristics. In addition, the RF receiver can support the overall TV band by controlling a LO frequency. The simulated results show a voltage gain of 56 dB, a noise figure of less than 2 dB, and an out-of-channel IIP3 of -2.3 dBm. It consumes 37 mA from a 1.5 V supply voltage.

• Korean Journal of Optics and Photonics
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• v.35 no.4
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• pp.157-163
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• 2024

We developed a 3-channel fiber laser with a common seed and a phase control system for laser beam combining through a diffractive optical element. Beam combining was performed by adjusting the angles of the beams incident on the diffractive optical elements, and the phase of each beam was controlled to maximize the intensity of the combined laser beam. The power of the 3-channel laser before passing through the diffractive optical elements is about 65 mW. The power of the combined beam varied between 2.9 mW and 48.3 mW depending on the phase change of each channel. Through phase control, the output of the combined beam can be maintained at 42 mW for more than 91.8% of the total time. It is expected that higher combining efficiency can be achieved by improving the transmittance of the diffractive optical elements and the performance of the phase control system.

• Journal of Navigation and Port Research
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• v.30 no.9
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• pp.755-762
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• 2006

When we consider to develop a new harbor, the most important factor, we think, is the lowest water depth of waterway and approaching channel for safe navigation of vessel. The existing harbors have been being dredged to meet the international trend of jumbo sized vessels by adopting the new design criteria. As the dredged materials over the expected at the design level were common and there are still lack of land based reclamation area, we have no choice to discharge the dredged materials in open sea area In this study, we analysed the behavior of discharged materials at the dumping area of offshore, which were collected from the dredging work at the waterway in Busan New Port. We measured the tidal currents and analyzed the waters of dumping site after the dumping work. These were used to evaluate the numerical models. Suspended Solids(SS) were introduced to the diffusion model. Because of the characteristic of the dumping site, the speed of initial diffusion and settle down of the discharged materials was so fast. Therefore, we believe that the dumped materials do not cause a significant impact to the marine environment.

• Nuclear Engineering and Technology
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• v.39 no.2
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• pp.133-142
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• 2007

The Electric Power Research Institute (EPRI) demonstrated a method for monitoring the performance of instrument channels in Topical Report (TR) 104965, 'On-Line Monitoring of Instrument Channel Performance.' This paper presents the results of several models originally developed by EPRI to monitor three nuclear plant sensor sets: Pressurizer Level, Reactor Protection System (RPS) Loop A, and Reactor Coolant System (RCS) Loop A Steam Generator (SG) Level. The sensor sets investigated include one redundant sensor model and two non-redundant sensor models. Each model employs an Auto-Associative Kernel Regression (AAKR) model architecture to predict correct sensor behavior. Performance of each of the developed models is evaluated using four metrics: accuracy, auto-sensitivity, cross-sensitivity, and newly developed Error Uncertainty Limit Monitoring (EULM) detectability. The uncertainty estimate for each model is also calculated through two methods: analytic formulas and Monte Carlo estimation. The uncertainty estimates are verified by calculating confidence interval coverages to assure that 95% of the measured data fall within the confidence intervals. The model performance evaluation identified the Pressurizer Level model as acceptable for on-line monitoring (OLM) implementation. The other two models, RPS Loop A and RCS Loop A SG Level, highlight two common problems that occur in model development and evaluation, namely faulty data and poor signal selection

• Journal of Korea Society of Industrial Information Systems
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• v.16 no.5
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• pp.21-30
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• 2011

In this paper, we propose a real-time service based on retransmission slot in low rate WPAN. In the proposed scheme, during the communication period of the beacon-enabled mode in LR-WPAN standard, a special GTSs is dynamically assigned for retransmission of the packet that fails during a real-time service such as voice. This provides a time diversity in the severe channel error environments to support the required QoS. Analytical results show that this scheme achieves a much higher throughput and better transmission success rate per GTS slot than conventional schemes such as a common reserved scheme in LR WPAN.