• 한국자원식물학회지
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• 제26권3호
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• pp.347-354
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• 2013

Apple and pear are popular fruits consumed in Korea and are common fruit in daily diet. In order to compare the antioxidant activity of the apple and pear peels, total polyphenol contents, total flavonoid contents, $ABTS^+$ free radical scavenging activity, and DPPH free radical scavenging activity were measured from hot water, ethanol, and methanol extracts of the two fruit peels. The total polyphenol and flavonoid contents were highest in 95% methanol extracts of the apple peelsand 70% ethanol extract of the pear peels, respectively. Total polyphenol contents of the pear peels were higher than that of apple peels, and total flavonoid contents of the apple peels were higher than that of pear peels. The apple and pear peels had the highest $ABTS^{+{\cdot}}$ and DPPH free radical scavenging activity in 95% methanol extracts and 70% ethanol extracts, respectively. $ABTS^{+{\cdot}}$ and DPPH free radical scavenging activity of pear peels was higher than that of apple peels, and the DPPH free radical scavenging activity of apple and pear peels were detected in hot water, 95% methanol, and 70% ethanol extracts, respectively. Ascorbic acid, a synthetic antioxidant used as positive control, had significantly higher scavenging activity than the apple and pear peels. In conclusion, the apple and pear peelshave great potential as natural antioxidants. Therefore, above results should be considered to provide the possibility for the development of high functional antioxidants.

• 농촌의학ㆍ지역보건
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• 제23권2호
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• pp.295-303
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• 1998

Toxocariasis is a parasitic zoonosis caused by infestation of humans with larvae of Toxocara canis, the common roundworm in dogs. Two syndromes have been identified : visceral larva migrans and ocular toxocariasis. In this study we were characterized proteinase activity in crude extracts from liver, lung, kidney and heart of mice infected with Toxocara canis and the dynamics of their changes in different stages of disease. The optimal pH was 5.5. In liver of mice infected with Toxocara canis, the maximun activity of proteinase was observed in 5 day post infection. In lung, the activity reached its maximun on 5th day in A group (infected with 100 embryonated eggs), and on 5th week in B group (infected with 50 embryonated eggs). In kidney, the maximum activity was shown at 6th week in A group, and in B group was shown at 10th day. In early infection, the activity reached its maximun in heart of mice infected with Toxocara canis. As we could see, the dynamics of the changes of proteinase activity in mice is similar in the case of the disease with other biochemical and immunological indices observed in toxocariasis.

• 가정과삶의질연구
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• 제34권1호
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• pp.1-12
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• 2016

The purpose of this research is to find out the differences of participation in common activities and life satisfaction of Swedish senior cohousing residents between the years of 2001 and 2010 by conducting a longitudinal study. The same questionnaire were surveyed nationwide to 186 residents of 8 Senior $G{\aa}rden$ cohousings in 2001 and 127 residents of 4 +40 cohousings in 2010, resulting in total 313 respondents' data. The results show that the +40 cohousing respondents are more likely than Senior $G{\aa}rden$ cohousing respondents to participate in all common activities, especially common meals and common coffee meetings. However, the subjective evaluation of the quantity as well as the contents of participating in common activities does not statistically differ in the two groups and life satisfaction is similarly high with a few differences. The +40 cohousing respondents are less likely to stay at and more likely to move into age-mixed cohousing if they have a chance to move when compared to their Senior $G{\aa}rden$ cohousing counterparts. The result of this research reveals that the general characteristics of senior cohousing residents have been changed and they have become more likely to be active participants of various common activities and have high life satisfaction.

• 생태와환경
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• 제47권spc호
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• pp.66-73
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• 2014

수달 서식지의 식생구조를 밝히고, 식생이 수달의 서식지 선택 요인 중의 하나인지를 구명하고자 연구하였다. 강원도 화천군의 북한강 본류와 지류 지천에서 수달흔적 발견지와 미발견지를 조사하였다. 수계의 식생형은 세 유형(단경초지형, 장경초지형, 관목지형)으로 구분되었다. 단경초지는 연수위변동이 큰 파로호와 북한강 상류에 분포하며, 명아자여뀌 (Persicaria nodosa), 하늘지기 (Fimbristylis dichotoma), 좀명아주 (Chenopodium ficifolium) 같은 일년생식물이 매우 우점한다. 관목지는 지촌천의 하류와 파로호 하부의 북한강 본류에 분포하며, 버드나무 (Salix koreensis)가 절대 우점하였다. 장경초지는 지류 하천에서 흔하며 거의 달뿌리풀 (Phragmites japonica) 순군락이다. 세 유형의 식생에서 수달의 흔적은 모두 발견되었으나 수달 미발견지는 모두 장경초지이었으며, 수달 발견지와 미발견지 간에 장경초지 식생의 상관이나 종조성은 유사하였다. 그러므로 수달이 서식지 선택 시 특정한 식생형을 선호한다고 보기는 어렵다. 다만, 수달 흔적이 발견되지 않은 장경초지는 지류의 상류로써 어류풍부도가 낮은 점이 공통적이다. 수달의 서식지 선택에 먹이인 어류의 풍부성이 가장 주요한 요인인 것으로 판단된다. 어류 풍부도가 높고 사람의 영향이 적은 평화의 댐 지역이 화천군의 수달분포에 최적지인 것으로 보인다.

• 재활치료과학
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• 제13권2호
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• pp.53-67
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• 2024

목적 : 이 연구의 목적은 지역사회에 거주하는 미국인과 한국인이 참여하는 일상적 활동 중 공통된 활동을 도출하는 것과(연구 1) 생애주기 변동에 따라 한국인의 활동 참여 패턴의 변화를 분석하는 것이다(연구 2). 연구방법 : 온라인 조사를 통해 Activity Card Sort version 3 (ACS-3)를 미국인과 한국인에게 적용하였다. 연구 1에서는 100개 활동에 대한 참여수준의 평균을 분석하고 결과를 시각자료로 제시했다. 연구 2에서는 4개 연령집단의 참여수준의 평균이 ACS-3의 4개 도매인별로 어떻게 변화하는지를 분석하고 시각자료로 제시했다. 결과 : 연구 1에서는, 161건의 미국인 자료와 163건의 한국인 자료를 분석하였다. 100개 활동 중, 48개 활동(수단적 활동: 20개, 여가 활동: 13개, 건강 활동: 6개, 사회활동: 9개)에서 두 국가간 유사한 참여수준을 확인하였다. 연구 2에서는, 420건의 한국인 자료를 분석하였다. 나이가 들어감에 따라 모든 수단적 활동을 제외한 모든 도매인에서 참여수준이 저하되는 경향을 확인하였다. 결론 : 서로 다른 문화권에서도 공통적인 일상활동은 작업치료에서 문화의 제한을 받지 않는 치료적 수단으로 활용할 수 있다. 노인의 일상활동 참여를 최적화하기 위한 보호적 접근과 지지가 제안된다.

• Journal of Nutrition and Health
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• 제11권3호
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• pp.37-42
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• 1978

Actomyosin and myofibril were extracted from Korean native Goat muscle with the Weber-Edsall solution. ATPase activities and physiochemical properties were measured. The results obtained were as follows; 1) Mg-activitied ATPase activity of actomyosin and myofibrill from Korean native Goat muscle exhibited a common biphasic response, a typical ATPase pattern, that is high at a low ionic strength and low at a high ionic strength. Actomyosin showed high activity than myofibrill. 2) Mg-activited ATPase activity of actomyosin from muscle increased extraction time 24 hours. 3) EDTA-enhanced ATPase activity of actomyosin was greater than myofibrill and low at the low ionic strength, high at the high ionic strength. The difference of the activity were shown great broad pattern at the after 0.3M KCI concentration. 4) Effect of EGTA on-ATPase activity of myofibrill and actomyosin from muscle was measured, the Mg-ATPase activity was markedly depressed. 5) Solubility of actomyosin from muscle began to solubilize at KCI concentration of 0.28M and solubilized completely at the KCI concentration of 0.3M.

• The Journal of Korean Physical Therapy
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• 제25권1호
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• pp.10-15
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• 2013

Purpose: Low back pain occurs and frequently recurs in many people. An imbalance of paraspinal muscle activity can cause low back pain. Mulligan's concept of mobilizations with sustained natural apophyseal glides (SNAG) is a common method for treating low back pain. The purpose of this study was to investigate the effects of this method on paraspinal muscle activity in patients with chronic low back pain. Methods: Twenty-one patients with low back pain participated in this study. Patients were classified using the Oswestry disability index. The subjects' paraspinal muscles were measured by surface electromyography both before and after the SNAG mobilization. We measured the root mean square value of the paraspinal muscles during lumbar flexion and extension. Results: Paraspinal muscle activity in patients with chronic low back pain was different between the right and left sides. Importantly, paraspinal muscle activity significantly decreased after using the SNAG mobilization method. Conclusion: This study shows a difference between paraspinal muscle activity in chronic low back pain patients and finds that the Mulligan's concept of SNAG mobilization is effective at reducing imbalances in paraspinal muscle activity in low back pain patients.

• 약학회지
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• 제49권2호
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• pp.122-127
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• 2005

Dental caries is one of the most common oral diseases in the world. Glucosyltransferase (Gtase) of Streptococcus mutans (S. mutans) plays an important role in the develo pment of dental caries. For the purpose to develop anti- caries, we examined the effect of metabolites isolated from Streptomyces sp. M-20 on Gtase and the growth of S. mutans. Streptomyces sp. M-20 isolated from Mongolian soil showed 95~96% sequence homology with that of Streptomyces lin- colnensis. The metabolites of Streptomyces sp. M-20 were partially purified by extraction with ethyl acetate, silica gel column chromatography and preparative TLC. Partially purified metabolite, red colored component (MR-20) in ethyl acetate fraction showed potent antibacterial activitiy against S. mutans and inhibitory activity against Gtase purified from S. mutans, while another isolated yellow component (MY-20) showed no activity against S. mutans. The inhibitory activity of MR-20 against Gtase was confirmed by activity staining on SDS-polyacrylamide gel electrophoresis. The concentration of MR-20 for 50% inhibition $(IC_{50})$ against Gtase activity was $60{\mu}g/ml$. These results suggest that MR-20 can be developed for antibacterial agent and anticaries.

• Journal of Applied Biological Chemistry
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• 제61권4호
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• pp.367-370
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• 2018

Lysozyme is an antibacterial enzyme that is found in most of body fluids. Lysozyme in tears plays a primary role in protecting eye from harmful environments; if lysozyme is degraded or inhibited, eyes are likely to be more vulnerable to bacterial infection. In this study, lysozyme activity was evaluated according to varying concentrations of heavy metals, copper, zinc, cobalt and manganese and light metal, calcium that are frequently found in airborne particulate matters and was assayed using a dye-quenching lysozyme substrate, Micrococcus lysodeikticus. Less fluorescence intensity was observed with increasing amounts of copper, zinc, manganese and cobalt but not with calcium suggesting that these metals have some affinity with lysozyme and inhibit lysozyme activity. When albumin, the second most common protein in tears, was added on the reaction of lysozyme and metals, lysozyme activity was partially restored. This finding suggests that the albumin might protect damage caused by metals on lysozyme. To identify whether the decrease in enzymatic activity was related to structural changes of lysozyme, SDS-PAGE was conducted and only with copper did lysozyme show marked smearing bands on the SDS-gel, meaning that copper degraded lysozyme consistent with the sharpest activity decrease.

• 한국작물학회지
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• 제59권2호
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• pp.201-207
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• 2014

본 연구는 강낭콩 싹나물의 재배시 재배온도에 따른 싹나물의 재배특성 및 항산화 활성을 분석하여 강낭콩을 이용한 채소용 싹나물 재배방법 구명과, 강낭콩 싹나물이 가진 성분 및 활성 등을 분석하여 최적 재배 조건을 구명하기 위하여 수행하였다. 1. 강낭콩 싹나물 재배를 위하여 $20^{\circ}C$, $23^{\circ}C$ 및 $25^{\circ}C$의 온도에서 5일간 재배한 결과 전장 및 배축장은 $23^{\circ}C$에서 재배하였을 경우 가장 우수하게 재배되었으며, 배축직경의 경우는 온도와 상관없이 모두 유사하게 재배되었다. 2. 재배온도별 강낭콩 싹나물의 불완전발아율 및 수율을 측정한 결과 재배온도별로 큰 차이를 보였으며, $20^{\circ}C$ 및 $25^{\circ}C$에서 재배 시 50%가 넘는 불완전발아율을 보였으나, $23^{\circ}C$에서는 10% 내외로 나타났다. 3. 강낭콩 싹나물의 재배온도별 조지방 및 조단백질 함량을 분석한 결과 재배온도 및 강낭콩 품종에 따라 큰 차이를 나타내지 않았다. 4. 재배온도($20^{\circ}C$, $23^{\circ}C$ 및 $25^{\circ}C$) 및 일수(0일, 3일, 5일 및 7일)별 강낭콩 싹나물의 폴리페놀 함량 및 라디칼 소거능을 측정한 결과 재배온도 및 일수가 증가함에 따라 폴리페놀 함량 및 라디칼 소거능이 증가하였으며, 특히 $23^{\circ}C$에서 재배 시 가장 높은 폴리페놀 함량 및 라디칼 소거능을 나타냈다.