• Title/Summary/Keyword: Combined Prescription

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Anti-leukemic effects of JIPAESAN and its components on leukemic cells HL-60 (인간백혈병(人間白血病) 세포주(細胞株)에서 지패산(芷貝散)의 작용(作用)에 관(關)한 연구(硏究))

  • Hwang Kee-Myoung
    • Herbal Formula Science
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    • v.10 no.1
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    • pp.143-155
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    • 2002
  • In the hope of identifying anti-leukemic agents from traditional herbal medicines. this study was designed to investigate the anti-leukemic effects of the herbal medicine Jipaesan, which is composed of Angelica Dahurica and Fritillariae Verticillata. in acute promyeloid leukemia HL-60 cells. Jipaesan showed anti-proliferative effect through the induction of differentiation and apoptosis in HL -60 cells. Verticinone as a major differentiating agent and imperatorin as major apoptosis-inducing agent were isolated from the water extracts of F. Verticillata and A. Dahurica, respectively. Combined treatment of HL-60 cells with two major compounds showed synergy in the induction of differentiation. Since the induction of differentiation and/or apoptosis has therapeutic values in curing acute leukemic diseases. Jipaesan could be useful as an anti-leukemic agent.

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A Study on Maekmundong(Liriope platyphyllla) of Soyosan in "Dong-uibogam(東醫寶鑑)" ("동의보감(東醫寶鑑)"의 소요산(逍遙散)에 포함된 맥문동(麥門冬)에 관한 고찰(考察))

  • Song, Ji-Chung;Keum, Kyung-Soo;Eom, Dong-Myung
    • Journal of Korean Medical classics
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    • v.22 no.3
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    • pp.211-225
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    • 2009
  • Soyosan is one of the most famous prescription in Oriental Medicine. It was showed for the first time in "Hwajegukbang(和劑局方)", the book of prescriptions, published in Song Dynasty, 1078. However, Soyosan did not include Maekmundong. Heojun as a author, made "Dong-uibogam" in 1613. Soyosan of "Dong-uibogam" had Maekmundong. In this study, I focused on how to get Maekmundong in "Dong-uibogam". Nonetheless, Soyosan originally didn't have Maekmundong. Soyosan and Maekmundong combined easily when Soyosan controlled disease related with Heat[熱]. Therefore, I suggest author or editor might put Maekmundong to Soyosan in "Dong-uibogam".

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A Study on the Combinations of Prescriptions in "Osibi-byeongbang . Jeobyeong(五十二病方 . 疽病)" ("오십이병방(五十二病方) . 저병(疽病)"의 방제(方齊) 구성(構成)에 대한 소고(小考))

  • Kim, Do-Hoon;Baik, You-Sang
    • Journal of Korean Medical classics
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    • v.20 no.3
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    • pp.23-32
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    • 2007
  • For the purpose of understanding the feature of earlier prescriptions before Jeonhan-era(前漢時期), we invastigated "Osibi-byeongbang Jeobyeong(五十二病方 疽病)" and come to the follwing conclusions. 1. Hwanggi and Baeglyeom were combined in many cases of prescriptions. And Warming and Heating herbs such as Gye(桂), Gang(薑), Cho(椒) are the main herbs in combination of the herbs and adjusting the portions. 2. Out of inspection of the Current prescriptions of Jeobyeong(疽病), we find that the remedies were very diverse at that time. There are the synthetic methods of expelling toxin from within the body method, elimination from within method, sweat-inducing method, replenish Eum and Heat-reducing method. 3. The principles of combinations of prescriotions in "Osibi-byeongbang Jeobyeong(五十二病方 疽病)"are simple and have obvious orientations in remedies.

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A Review of Experimental Study for Herbal Medicines of Anti-allergic Effects (항알레르기 효능을 가진 한약물의 실험 연구 결과에 대한 고찰)

  • Lee, Woo-Gun;Hong, Eu-Gene;Kim, Bong-Hyun;Kim, Kyu-Seok;Nam, Hae-Jeong;Kim, Yoon-Bum
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.25 no.3
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    • pp.34-55
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    • 2012
  • Objective : The purpose of this study is to survey the experimental studies for Herbal Medicines of Anti-allergic Effects by reviewing oriental medicine journals. Methods : We collected 48 research papers on Oriental herbal medicines (prescriptions, herbs and aqua-acupunctures) of Anti-allergic effects in the internet site OASIS using the keyword 'Antiallergy'. Then we analyzed them according to published journals, years, and research methods, etc. Results : 48 papers in relation to Oriental herbal medicines of anti-allergic effects have been published in many kinds of journals and shows a tendency to increase every year. There are 23 cases of using herb simplexes, 21 cases of herb-combined prescription, and 4 cases of aqua-acupuncture. Conclusions : This result will provide useful information of field of Oriental herbal medicine for the development of anti-allergic related herb simplexes and herb combined prescriptions. In the future, we have to perform more studies such as clinical trial and research papers on combined medication of the oriental and the western medicines for anti-allergic effects.

Comparison Study for Body Composition and Physical Function Fitness to the According of Exercise Type in Elderly Women

  • Lee, Jin-wook
    • Journal of the Korea Society of Computer and Information
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    • v.26 no.4
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    • pp.133-142
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    • 2021
  • The purpose of this study was to examine the most suitable exercise for the elderly women by comparing the changes in body composition and physical function fitness after modern dance, aquarobic and combined exercise programs for the elderly women. The subjects of this study were 47 elderly women in J-do, chosen as MDG(n=13), AEG(n=11), CEG(n=11) and CG(n=12) for participated for 60 minutes/day and three times/wk for 12 weeks. The results of grip strength, chair stand, arm curl, 2 minute step, 244cm up and go was significantly than in the control group. Back scratch was decreased significantly after exercise only in the modern dance group and combined exercise group but there was no change in chair sit and reach. These results suggest that various exercises were found to play a positive role in maintaining and improving fitness for the elderly women. In addition, additional exercise programs are needed to improve flexibility and mobility of joints for the elderly. It is thought that it is important to voluntarily participate in a movement that suits your interests to make it sustainable.

A study of the tendency of anti-cancer experimental study using herbal medicines (한약(韓藥)을 이용(利用)한 항암(抗癌) 실험연구(實驗硏究)의 경향(傾向)에 관(關)한 고찰(考察))

  • Kim, Hyung-A;Lim, Sung-Woo;Lee, Won-Chul
    • THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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    • v.4 no.1
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    • pp.211-232
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    • 1998
  • Because there were lots of side effects and tolerances to the existing anticancer therapeutics, the experiment extracting the anticancer effect from medicinal herbs is in progress liviely. Therefore the purpose of this study were to research the tendency and the course of anticancer studies. To research the tendency of anticancer studies, medicinal herbs of fifty three experimental papers were analyzed and to examine the course of studies, anticancer papers in the medical world were used. The obtained results were as follows: Methods of herbal medicinal treatments were elimination the pathogenic factor(祛邪) and supporting healthy energy(扶正) method used. In this study, immediately tumor bearing and immune response were the most important point. The subject of immediately tumor bearing was not in the specific cancer but in the influence on the life span of general cencerous cells. In the experimental study of immune response, the effect on NK cell activity of medicinal herbs most studied. The combined usage of medicinal herbs and anticancer agent mostly intended to know whether it inhibits the tumor cell growth. The serum test and blood cell number test show if medicinal herbs inhibit side effect of anticancer agent. More than 80 percents of used medicinal herbs, there were anticancer activities. However anticancer experimental studies using medicinal herbs two weak points. The one, it was difficult to choose a prescription according to differentiation of symptoms and signs(辨證論) of the Oriental Medicine, because we put to the test not a man but a mouse. The other, as we observed the indirect effect of the whole physiological regulation caused by synergic effects of the complex prescription, we don't understand the detailed mechanism of the herb. Therefore, if the anticancer effect of the herb is proved the experiment, we should research the concrete medical action of medicinal herbs and immunological analysis of herbal medicines to the body.

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Study on the Confidential Document of A Distinguished Medical Family (기문비록(岐門秘錄)에 대한 고찰)

  • Kim, Dong-Min;Choi, Kyung-Suk;Shin, Seung-Yuel;Ahn, Jun-Mo;Keum, Kyung-Soo;Lee, Si-Hyeong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.22 no.5
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    • pp.1078-1105
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    • 2008
  • An empirical formula that has been empirically shown to be effective for a particular condition can be said to add medicinal materials to an existing formula or to make a new prescription by the Korean medical doctors' empirical clinic. This dissertation aims to study the prescriptions according to A Confidential Document of A Distinguished Medical Family written by the writer's ancestor and to contribute to the development of Korean medicine. A Confidential Document of A Distinguished Medical Family is a medicinal recipe that is an heirloom of the Gyeongju Kim family for the eighth generation. And the date and the writer of the book are unknown. The contents of the book consist of 18 parts and are made up of about 300 medical recipes. Of these, 158 formulas and indications of cold damage, wind, urination, stool, jaundice, and internal injury are found in the book. From among these, 61 formulas was directly quoted out of The Precious Mirror of Oriental Medicine, 97 formulas are adjusted in proportion or combined. By the parity of reasoning of the above, I think that this book was published after The Precious Mirror of Oriental Medicine. I will continue to study other formulas except the formulas above mentioned.

Suggestion of Law for Supporting u-Healthcare's Activation (유비쿼터스 보건의료서비스 활성화지원 법률안의 제안)

  • Cho, Hyong-Won
    • The Korean Society of Law and Medicine
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    • v.10 no.1
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    • pp.171-211
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    • 2009
  • Because Korea has the excellent informational technology, it was expected to be able to improve the accessibility to healthcare and compete with other nations in excellence through u-Healthcare. But we can't complete the excellent u-Healthcare because of the law to be able to use only the tele-counselling between doctor to doctor or doctor to nurse. First of all, we must complete the law to be able to use the improved u-Health containing of telemedicine between doctor to patient. Though other factors, the procurement of safe IT, the credibility to healthcare service provider containing of nutritionist and occupational therapist etc. are prepared for erecting u-Healthcare, we can get the final and decisive u-Health policy only by means of Law for supporting u-Healthcare's Activation. The important sections of Law for supporting u-Healthcare's Activation are as follows. Sec. 4 The Minister for Health, Welfare and Family Affairs and the dean of associated administrative division have to erect the combined plan for u-Healthcare's Activation. Sec. 11 Government and local autonomous entity can support the facility and equipment to be necessitated for using u-Healthcare to improve the medical accessibility of person in the region with poor medicine. Sec. 13 Doctor can support other doctor's medical action through IT and if there are not medical risk, doctor can give medical act directly to the special patients. Sec. 21 If pharmaceuticals is necessitated in u-Healthcare, remote doctor has to send the patient the electronic prescription and the pharmaceutist to receive the electronic prescription has to delivery the pharmaceuticals in accordance with patient's demand.

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A Case Report on The Relieving Effect of Herbal Medicine on Clinical Symptoms in Patients with Hyperthyroidism Taking Methimazole (메티마졸 투여 중인 갑상선기능항진증 환자에서 한약의 임상증상 완화효과에 대한 증례보고)

  • Henja Yun
    • Herbal Formula Science
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    • v.31 no.3
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    • pp.203-213
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    • 2023
  • Objectives : The purpose of this study is to report the symptomatic relief effect of a herbal prescription combined with methimazole for hyperthyroidism caused by Graves' disease. Methods : After diagnosis of hyperthyroidism, methimazole was initially administered alone. As the clinical symptoms continued, a herbal medicine combining Gamiondam-tang and Cheongsimyeonja-eum was administered together with methimazole. Blood concentrations of hormones were measured, and the degree of clinical symptoms was measured using the NRS scale. The effect of herbal medicine on heat intolerance was analyzed by Wilcoxon rank sum test, and the relationship between thyroid hormone and heat intolerance was analyzed by Pearson's correlation coefficient. Results : Heat intolerance symptoms were significantly reduced when the herbal prescription was administered in parallel than when methimazole was administered alone (w=296, p=0.001). The decrease in heat intolerance was not related to thyroid hormone levels (p=0.27, 0.37). Conclusions : It was found that the herbal medicine combining Gamiondam-tang and Cheongsimyeonja-eum was effective in treating hyperthyroidism symptoms including heat intolerance.

Enhancing Communication on Medication Side Effects: Insights from a Survey Study (의약품 부작용 정보 전달의 중요성: 설문조사 기반 고찰)

  • Ji Hye Choi;Hye Seong Han;Mi Kyong Shim;Hyun Soon Sohn
    • Korean Journal of Clinical Pharmacy
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    • v.34 no.2
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    • pp.126-133
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    • 2024
  • Background: Medication's benefits and harms require careful management. Laws mandate pharmacists to provide essential medication details since inadequate counseling may pose risks. This study explores public expectations for pharmacist-provided side effect information to enhance safety. Methods: A self-developed questionnaire was created for participant to self-report, refined through pilot surveys with experts and laypersons. Nineteen items were categorized into four sections, using closed-ended questions. Adults over 20, having obtained prescription medications within the past year, were surveyed via convenience sampling. Data analysis employed descriptive statistics and T-tests using IBM SPSS Statistics 21 and Microsoft Excel. Results: The study involved 189 participants, with a slightly higher proportion of females (59.3%) than males (40.7%), predominantly in their 20s (45.0%) and college graduates (57.1%). Health professionals represented 76.2% of respondents. Over half visited pharmacies at least 5 times yearly for prescriptions. Indirect experience with side effects was more common (30.2%) than direct experience (17.5%). Most (82.0%) showed interest in media-reported side effect events. Satisfaction with pharmacist-provided side effect explanations was low (59.7%), but importance was high (98.9%). Preferences favored combined verbal and written explanations (65.1%), with a majority desiring explanations for common but less serious side effects (82.5%). Healthcare professionals found explanations significantly more sufficient than non-professionals did. Older individuals, those living with elderly, and frequent pharmacy visitors attributed greater importance to pharmacist-provided explanations. Conclusion: Koreans view pharmacist-provided medication side effect explanations as vital but find current services lacking. Enhancements in content and delivery methods are needed in pharmacy counseling to meet public expectations.