• KSBB Journal
• /
• v.22 no.5
• /
• pp.318-321
• /
• 2007

Photodynamic therapy (PDT) is a targeted-tumor treatment system using a photosensitizer, light and oxygen to treat malignant tumor. We have investigated the cytotoxicity of 4 types of phthalocyanine derivative (silver phthalocyanine, iron (III) phthalocyanine, copper (II) phthalocyanine, nickel (II) phthalocyanine) against lung and breast cancers based on photodynamic therapy. As a result, phthalocyanine derivatives indicated a higher anticancer activity on a breast cancer cell line. Among the tested phthalocyanines, silver phthalocyanine (AgPc) showed a lower cytotoxicity against a normal cell line. In addition AgPc gave a good color characteristic when it is solubilized in water. Finally AgPc was selected as a potential antitumor agent for breast cancer.

• Journal of Korean Academy of Nursing
• /
• v.23 no.3
• /
• pp.431-452
• /
• 1993

This study was done to determine the effect of music therapy on stress and quality of life in patients undergoing hemodialysis. The research design was a nonequivalent control group pre -post test design. The subjects consisted of 21 patients who received hemodialysis in two hospitals located in Kwang Ju. The fourteen receiving treatment in one hospital were assigned to the experimental group and the seven in the other hospital to the control group. Data were gathered from December 14, 1992 to January 16, 1993 through questionnaires and physiological measurement. Data were analyzed by the SAS package using frequency, t-test, paired t-test and Pearson Prod uct - Moment Correlation Coefficient. The results of this study are summarized as follows ; 1. There were no significant differences between the two groups on stress scores and quality of life scores before the treatment. 2. The mean score on the psychological stress scale for the patients undergoing hemodialysis was 2.48 out of a maximum mean score of four, the items with high stress scores were “feeling of weakness and annoyed by everything”, “limitation of food”, “limitation of fluid”, “change in skin color” in that order. The psychological category showed the highest stress score followed by developmental, scoioeconomic and physiological stress categories in that order. 3. In the experimental group, post - test diastolic blood pressure decerased significantly(t=3.24, p=0.0064), but in the control group pre and post - test diastolic blood pressure were not different. 4. There was no difference between the two groups on the pre and post -test psychological stress scores or the depression scores. 5. The mean score of quality of life for patients undergoing hemodialysis was 2.75 out of a maxi-mum mean score of five. The category of ‘emtional state’ showed the highest score followed by ‘self - esteem’, ‘physical state and function’, ‘economic life’, ‘relationship with neighbors’ and ‘family relationship’ categories in that order. There was no significant difference in the pre and post - test quality of life scores between the two groups. 6. Hypothesis 1 that patients undergoing hemodialysis who received music therapy would have less stress than patients undergoing hemodialysis who did not receive music therapy is divided into two sub - hypotheses. 1) The first sub-hypothesis that patients undergoing hemodialysis who received music therapy would have less physiological stress than patients undergoing hemodialysis who did not receive music therapy was partly supported. Among three physiological stress indices (pulse, systolic blood pressure, diastolic blood pressure), only diastolic blood pressure decreased significantly after the treatment in the experimental group. 2) The second sub-hypothesis that patients undergoing hemodialysis who received music therapy would have less psychological stress than patients undergoing hemodialysis who did not receive music therapy was not supported. Psychological stress score and depression score were not significantly different before and after the treatment. 7. Hypothesis 2 that patients undergoing hemodialysis who received music therapy would have a higher quality of life score than patients undergoing. hemodialysis who did not received music therapy was not supported. There were no significant changes in the quality of life scores before and after the treatment.

• Therapeutic Science for Rehabilitation
• /
• v.11 no.3
• /
• pp.81-92
• /
• 2022

Objectives : This study aimed to investigate the effect of beat-keeping games in smartphone applications on improving executive functions in children with developmental delays. Methods : Three children diagnosed with developmental delay were included in this study. The ABA design used a single-subject experimental research design. The independent variable was the beat-keeping game. The game was held three times a week for a total of seven times for 20 minutes, including breaks. The dependent variable, "Visual-motor speed," was measured every session to assess if the beat-keeping game was effective in improving the participant's executive function. Further, before and after the intervention, "Children's Color Trails Test (CCTT)", "Block design," and "Finding hidden picture" were measured. Results : All three participants showed improvement in the performance of the beat-keeping game and the executive functions of "Visual-motor speed" and visual attention. Conclusions : Based on the results of this study, various effective applications for learning and intervention can be developed and applied to children with developmental delays who have difficulty in motivating themselves and lack attention.

• Archives of Reconstructive Microsurgery
• /
• v.20 no.2
• /
• pp.89-95
• /
• 2011

Purpose: The purpose of this study was to evaluate the clinical results of anterolateral thigh free flap on soft tissue defect following wide excision in malignant soft tissue tumor of lower extremities. Methods: Between February 2005 to April 2010, we followed up 19 cases who were undergoing anterolateral thigh free flap because of soft tissue defect following wide excision of malignant soft tissue tumor in lower extremity, including 9 cases were heel, 5 cases in foot, 3 cases in ankle, 2 cases in knee and leg. We observed that of implanted area's color, peripheral circulation at 3, 5, 7 days after operation and evaluated operating time, amount of hemorrhage, implanted skin necrosis, additional operations, complications. And we also evaluated the oncologic results, including local recurrence, metastasis, and morbidity. Results: Average operation time of wide excision and anterolateral thigh free flap was 7 hour 28 minutes. 18(94.7%) of total 19 cases showed successful engraftment, on the other hand, failure of engraftment due to complete necrosis of flap in 1 case. In 18 cases with successful engraftment, reoperation was performed in 4 cases. Among them, removal of hematoma and engraftment of flap after bleeding control was performed in 3 cases, because of insufficient circulation due to the hematoma. In the remaining 1 case, graft necrosis due to flap infection was checked, and grafted after combination of wound debridement and conservative treatment such as antibiotics therapy, also skin graft was performed at debrided skin defect area. Skin color change was mainly due to congestion with hematoma, flap was not observed global congestion or necrosis except 4 cases which shows partial necrosis on margin that treated with conservative therapy. Conclusions: Anterolateral thigh free flap could be recommended for reconstruction of soft tissue defect following wide excision of malignant soft tissue tumor in lower extremity.

• Journal of Fashion Business
• /
• v.11 no.4
• /
• pp.42-51
• /
• 2007

The purpose of this study is to develop clothing design for mild dementia patients who display positive action in clothing for the improvement of the quality of life of the dementia patients following the symptoms of patients in accordance with the clinical classification to provide the functional assistance for ordinary living as well as emotional stability and aesthetic functions for the dementia elderly. The method of research is performed for theories through the advanced research and documentary data, and interpreted in functional and aesthetic level on the basis of the result of advance survey related to the characteristics of the mild dementia patients and clothing conduct of elderly with light dementia to select the material, color, decoration and functional design with four pairs for women and two pairs for men. Designs for the total of six have been actually produced by making the map, including the material swatch, color and others. The questionnaire as the measuring tool is used and the assessment category is made for the adaptability of design on each category. On the six clothes that are produced for the mild dementia patients, the statistics package SPSS Ver 12.0 is used for the data analysis on questions 8-10 for the frequency analysis. In overall, the leisure clothing for mild dementia patients developed from this research are generally satisfied, and overall type, material, color, detail and arrangement are generally evaluated highly, and have the assessment of normal or better in the color size and type.

• Korean Journal of Acupuncture
• /
• v.28 no.3
• /
• pp.63-71
• /
• 2011

Objectives : The aim of this study is to develop the system and evaluate the optical analytical technique that reflects acupoint pigmentation and extravasated blood by cupping. Methods : We designed the system able to express XYZ coordinate on local skin color. To evaluate measurement-accuracy, we compared with 24 Color Checker Chart by standardized Commission Internationale de l'Eclairage. After confirming the performance of system, we experimented with cupping which was 80 kPa negative pressure for 1 minute on left/right BL13. The X, Y and Z values were converted to R, G and B, $L^*$, $a^*$ and $b^*$, Erythema Index (E.I.), and Melanin Index (M.I). We compared and analyzed two cases on before/after cupping. Results : The R, G and B values which were converted by X, Y and Z values had high linearity as a high level of R-square (R: 0.969, G: 0.996, and B: 0.992). Moreover, we confirmed that it was possible to quantitatively analyzed the change in skin color by cupping using R, G, B, $L^*$, $a^*$, $b^*$, E.I., and M.I. Conclusions : Therefore, we proposed the new analytical technique for objectifying the oriental medical diagnostic method using cupping and optical sensing technique.

• Journal of the Korea Convergence Society
• /
• v.10 no.5
• /
• pp.313-321
• /
• 2019

The purpose of this study was to examine music-color association response(MCAR) of people with visual impairment through music-emotion scale and music-color scale. The study was conducted on 60 participants(30 congenital/ 30 adventitious) who are using services of two welfare centers at S and B cities. For this, four basic emotions (happiness, sadness, anger, and fear) mediated by music were selected, and MCAR to emotion-inducing music were analyzed through self-report method. As a result, first, there were found contrasts in MCAR between happiness and sadness according to type of emotion, however, similar in anger and fear. Second, in MCAR among three variables of the music-emotion scale(valence, arousal and intensity), valence was congruent with MCAR according to type of emotion, arousal marked high scores in negative emotions, and scores of intensity in happiness and sadness were higher than those in anger and fear. Third, there were no significant differences between two groups of people with congenital and adventitious visual impairments. It is meaningful that this study showed the MCAR can be mediated by music through investigating those of people with visual impairment.

• Journal of dental hygiene science
• /
• v.11 no.2
• /
• pp.121-127
• /
• 2011

This study was conducted to improve patients satisfaction by comparing patients expectation prior to the implant therapy to patient satisfaction after the implant therapy. The data of 158 patients with dental implant in Seoul, Gyeonggi-Do and Cheonan city was obtained. The results are as follows : 1. 40.5% of patients placed one implant and 36.1 % of patients answered that the average cost for each implant is from 1,500,000 to 2,000,000won. 23.4% of them answered they decided to have implant because no tooth preparation is required. 2. Overall, the expectation level for implant therapy in general properties, women showed higher level of expectation than men. Especially, 'Implant has a longer life than other denture' showed significant difference between women(4.29) and men(3.87). Expectation by age, 'Implant has similar color and shape' was found the highest in age 20(4.38). Satisfaction by general properties, 'No tooth preparation required' was found the highest in age 20(4.57) and was statistically significant(p<.002). 3. Comparing patients' expectation prior to implant therapy to satisfaction afterward, 'Implant prevents jawbone resorption and keeps facial appearance' showed 3.7 of expectation but satisfaction was found increased to 3.87(p=.020). No tooth preparation required' was found 3.95 in expectation prior to implant therapy but after therapy it was found 4.23 in satisfaction (p<.001). 4. Overall satisfaction in implant therapy was found 4.25, recommendation to other patients was found 4.18 and repurchase was found 4.17.

• Journal of Sasang Constitutional Medicine
• /
• v.21 no.3
• /
• pp.216-222
• /
• 2009

1. Objectives: This case study described a process of the patient diagnosed as acute hepatitis A treated by medication based on the Sasang Constitutional Medicine and acupuctural theraphy and obtained improved effects about several symptoms. 2. Methods: We diagnosed the male patient with acute hepatitis A as Tae-Eumin Exterior-Cold-Disease by the Cold in the Esophagus, and administered Mahwangbalpyo-tang and Handayeolso-tang according to clinical progress. And we evaluated the results by liver function test(LFT; AST, ALT, $\gamma$-GTP ), total bilirubin level and the visual analog scale(VAS) of symptoms. 3. Results and Conclusion: Almost symptoms (except for jaundice) at the time of admission were disappeared, and also jaundice (estimated by color of scleras and color of urine) was alleviated. Also level of AST, ALT, $\gamma$-GTP and total bilirubin decreased in laboratory test. We obtained positive effects to the therapy but we considered necessities of further comparative studies with control group.

• Journal of Korea Technical Association of The Pulp and Paper Industry
• /
• v.47 no.5
• /
• pp.120-126
• /
• 2015

In this study, we used various dyes from natural pigments such as tumeric, goldthread, indigo, pagoda tree flower, sappanwood, and safflower to make the Hanji wallpaper with super eight colors of yellow, orange, green, turquoise, violet, red, blue, and magenta. As a result of measuring the lightfastness, magenta dyed with sappanwood showed the worst effect, but blue dyed with only indigo showed the best effect. In terms of the spot test by water, red wallpaper dyed with safflower showed the clear spot, but blue, turquoise, and green dyed with indigo resulted in a little spot. The orange, violet, and magenta dyed with goldthread and sappanwood showed antibacterial activity, and the turquoise, green, and blue also has a little antibacterial activity. However, yellow and red didn't show the some result as expected. In the experiment for efficiency of formaldehyde removal, all Hanji wallpapers dyed with natural pigments showed the significant removal effect of formaldehyde, especially turquoise and red were the highest.