• 한국균학회소식:학술대회논문집
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• 2018.05a
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• pp.19-19
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• 2018

Fungal pathogens have huge impact on health and economic wellbeing of human by causing life-threatening mycoses in immune-compromised patients or by destroying crop plants. A key determinant of fungal pathogenesis is their ability to undergo developmental change in response to host or environmental factors. Genetic pathways that regulate such morphological transitions and adaptation are therefore extensively studied during the last few decades. Given that epigenetic as well as genetic components play pivotal roles in development of plants and mammals, contribution of microbial epigenetic counterparts to this morphogenetic process is intriguing yet nearly unappreciated question to date. To bridge this gap in our knowledge, we set out to investigate histone modifications among epigenetic mechanisms that possibly regulate fungal adaptation and processes involved in pathogenesis of a model plant pathogenic fungus, Magnaporthe oryzae. For functional and comparative analysis of histone modifications, a web-based database (dbHiMo) was constructed first to archive and analyze histone modifying enzymes from eukaryotic species whose genome sequences are available. Based on the database entries, we carried out functional analysis of genes encoding histone modifying enzymes. Here I provide examples of such analyses that show how histone acetylation and methylation is implicated in regulating important aspects of fungal pathogenesis. Current analysis of histone modifying enzymes is followed by ChIP-seq and RNA-seq experiments to pinpoint the genes that are controlled by particular histone modifications. We anticipate that our work will provide not only the significant advances in our understanding of epigenetic mechanisms operating in microbial eukaryotes but also basis to expand our perspective on regulation of development in fungal pathogens.

• The Journal of the Convergence on Culture Technology
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• v.7 no.1
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• pp.518-524
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• 2021

The purpose of this study was to examine the correlation between academic achievement, major selection motivation, work value, and campus life adjustment of healthcare major college students. Data was collected using a structured questionnaire for 495 healthcare major college students at a four-year university located in G city. As a result of the study, Academic achievement was determined with positive correlation by major selection motivation (r=.446, p<.001), work values (r=.255, p<.001), campus life adjustment(r=.391, p<.001), Major selection motivation was positively correlated with work value (r=.354, p<.001) and campus life adjustment (r=.220, p<.001). The work value showed a positive correlation with the campus life adjustment(r=.193, p<.001). It is necessary to develop a career education program that reinforces college students' major selection motivation and their work values, and a student guidance program that improves their adaptation to college life.

• Korean Journal of Agricultural Science
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• v.47 no.1
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• pp.119-130
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• 2020

With the current rapid growth and increase in the world's population, the demand for nutritious food and fibers and fuel will increase. Therefore, there is a serious need for the use of breeding programs with the full potential to produce high-yielding crops. However, existing breeding techniques are unable to meet the demand criteria even though genotyping techniques have significantly progressed with the discovery of molecular markers and next-generation sequencing tools, and conventional phenotyping techniques lag behind. Well-organized high-throughput plant phenotyping platforms have been established recently and developed in different parts of the world to address this problem. These platforms use several imaging techniques and technologies to acquire data for quantitative studies related to plant growth, yield, and adaptation to various types of abiotic or biotic stresses (drought, nutrient, disease, salinity, etc.). Phenotyping has become an impediment in genomics studies of plant breeding. In recent years, phenomics, an emerging domain that entails characterizing the full set of phenotypes in a given species, has appeared as a novel approach to enhance genomics data in breeding programs. Imaging techniques are of substantial importance in phenomics. In this study, the importance of current imaging technologies and their applications in plant phenotyping are reviewed, and their advantages and limitations in phenomics are highlighted.

• Journal of the Korea Convergence Society
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• v.10 no.1
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• pp.353-360
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• 2019

Purpose: The depression of the elderly in recent years has been increasing every year due to the remarkable change of the psychological function, which has a great influence on the life. Depression which is a powerful predictor of suicide in elderly people, causes various psychological and social problems. In this study, we try to understand convergently about the adaptation experiences of the depressed elderly with suicidal ideation. Procedures and Methods: Seven elderly people with a GDS(Geriatric Depression Scale) score of ${\geq}17$ and a SSI(Scale for Suicidal Ideation) score of ${\geq}9$ in the self-help group were interviewed until theoretical saturation. Data were analyzed based on the Grounded theory method. Results and Contribution: Depressed elderly recognized the importance of being the center of their lives through interactions with peer groups and they started to embrace their lives. Further studies: Empirical studies on positive interactions with peer groups affecting the adjustment experience of depressed elderly should be expanded and continued.

• Journal of Ginseng Culture
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• v.3
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• pp.1-10
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• 2021

Panax ginseng (Ginseng or Korean ginseng) is one of the most important medicinal herbs in the world. We made a high-quality whole genome sequence of P. ginseng using 'Chunpoong' cultivar, which is the first cultivar registered in Korea Seed and Variety Service (KSVS) with relatively similar genotypes and superior phenotypes, representing approximately 3 Gbp and 60,000 genes. Genome sequence analyses of P. ginseng and related speciesrevealed the origin of Korean ginseng and the ecological adaptation of 18 Panax species around the world. Korean ginseng and American ginseng (P. quinquefolius) are tetraploid species having 24 chromosome pairs, while the other 16 species are diploid species with 12 chromosome pairs. Panax and Aralia are the closest genera belonging to the Araliaceae family that diverged approximately 8 million years ago (MYA). All Panax species evolved as shade plants adapting to cool climates and low light conditions under the canopy of deep forests from Southeast Asia such as Vietnam to Northeast Asia such as Russia approximately 6 MYA. However, through recurrent ice ages and global warming, most diploid Panax species disappeared due to the freezing winter, while tetraploid P. ginseng may have appeared by allotetraploidization, which contributed to the adaptation to cold temperaturesin Northeast Asian countries including the Korea peninsula approximately 2 MYA. American ginseng evolved by the adaptation of P. ginseng in Northeast America after the intercontinental migration 1 MYA. Meanwhile, most of diploid Panax species survived in high-altitude mountains over 1,600 meters in Southeast Asia because they could not endure the hot temperature and freezing cold. The genome sequence provides good basisto unveil the origin and evolution of ginseng and also supports practical gene chips which is useful for breeding and the ginseng industry.

• Journal of Korean Academy of Nursing
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• v.46 no.4
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• pp.583-597
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• 2016

Purpose: The study was done to evaluate the effects a Stress Management Program (SMP) on stress, problem solving skills, and quality of life for hospitalized patients with Schizophrenia. Methods: A mixed method design was used: a combination of a repeated-measure design with a non-equivalent control group and qualitative data collection. The participants were 40 patients with schizophrenia admitted in three psychiatric hospitals. The experimental group (n=20) received the SMP twice a week for a total of 8 weeks. Results: Study results revealed that the SMP was effective for stress (F=321.02, p<.001), problem solving ability (F=246.28, p<.001), and quality of life (F=63.35, p<.001) for hospitalized persons with schizophrenia. Conclusion: The results suggest that a SMP can be an effective strategy to reduce patients' hospitalization stress, and improve problem solving skills and quality of life. Therefore, it is recommended that mental health nurses use this stress management program in clinical practice to assist adaptation to hospitalization for persons with schizophrenia.

• Journal of Korean Academy of Dental Administration
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• v.10 no.1
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• pp.9-21
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• 2022

This study was carried out to understand the influence of dental technicians' image and major satisfaction on dental technology students' dropout intention. A questionnaire survey was administered to 273 students in the Department of Dental Technology. Frequency analysis, independent sample t-test, one-way ANOVA, and multiple regression analysis were performed. The results are as follows: The image of dental technicians differed significantly depending on factors such as school year, personality, whether a family member is a dental technician or not, reason for choosing a department, difficulty in one's own academic life, and disciplinary life adaptation (p<0.05). The image of dental technicians was seen to be positively perceived when the respondent had an affirmative personality, or had a dental technician among family members or chose the department for its uniqueness, or found no difficulty in academic life, and adapted well to a situational or environmental change. Major satisfaction of dental technicians was seen a meaningful difference in items such as school year, personality, awareness of dental technicians, reason for choosing a department, the difficulty in own academic life, and the disciplinary life adaptation (p<0.05). Individuals with high major satisfaction and low dropout intention included those with a positive personality, who think affirmatively about dental technicians, who chose a department owing to suiting the aptitude and interest or to the uniqueness of the major. The influential factors on dropout intention included general satisfaction out of major satisfaction, perspective and self-confident image among dental technicians, and an awareness of dental technicians. The establishment of a desirable image of dental technicians and the improvement in major satisfaction are considered likely to contribute to reducing the dropout intention of dental technology students.

• Applied Biological Chemistry
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• v.41 no.2
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• pp.197-200
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• 1998

The MeOH extracts obtained from the flower petals of Carthamus tinctorius were solvent-fractionated with EtOAc, n-BuOH, and $H_2O$, successively. From the n-BuOH extract 2 flavonoid compounds were isolated through the repeated silica gel column chromatographies. From not only the results of physico-chemical data including HMBC but also the adaptation of acid hydrolysis, the chemical structures of the compounds were determined as $3-O-[{\beta}-D-glucopyranosyl(1{\rightarrow}2)\;{\beta}-D-glucopyranosyl]\;kaempferol$ and $3-O-[{\alpha}-L-rhamnopyranosyl(1{\rightarrow}6)\;{\beta}-D-glucopyranosyl]\;kaempferol$. The compounds exhibited $IC_{50}$ values in Grab2-Shc activity to be 43 and $47{\mu}g/ml$, respectively.

• Applied Biological Chemistry
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• v.40 no.6
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• pp.583-587
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• 1997

The MeOH extracts obtained from the tuber of Ipomoea batatas Lam. were solvent-fractionated with EtOAc, n-BuOH, and $H_2O$, respectively. From EtOAc fraction four different compounds were isolated through the repeated silica gel column chromatographies. From not only the results of NMR and MS data but also the adaptation of hydrolysis, methylation, and acetylation, the chemical structures of compounds were elucidated as resin glycoside, simonin I, ${\beta}-sitosterol$, and two kinds of unsaturated fatty acids.

• Journal of Families and Better Life
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• v.18 no.1
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• pp.127-138
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• 2000

Theis study examined relationship between college student attachment to parents and two broad indices of adolescent adaptation -selfe-esteem and adjustment to college. Also the association of parental attachment bonds to college adjustment would be mediated by self-esteem was examined in this study. Participants included 381 college students(176 men 205 women) As expected parental attachment was positively related to self-esteem and college adjustment. gender of parent differences emerged in which attachment to father was a more important predictor of college adjustment than was attachment to mother. Self-esteem played a mediating role in relation between parental attachment and college adjustment, Furthermore self-esteem was a most significant predictor of college adjustment .