• 한국산학기술학회논문지
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• 제20권11호
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• pp.446-457
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• 2019

본 연구의 목적은 청소년 남학생 흡연과 가족구성원의 흡연의 관련성을 분석하기 위함이다. '제14차(2018년) 청소년건강행태조사'에 응답한 27,276명을 이용하여 빈도분석, 교차분석, 다중 로지스틱 회귀분석을 실시하였다. 남학생 중 비흡연율은 91.5%, 흡연율은 8.5%(가끔 흡연함 2.5%, 자주 흡연함 6.0%)이다. 연구결과, 가족구성원의 흡연자 수에 따른 남학생의 흡연 상태는 유의한 차이가 있다(p<0.001). 인구사회학적 특성에 따른 흡연은 학년, 학업성적, 경제상태, 아버지 학력, 어머니 학력에서 유의한 차이가 있고(p<0.001), 건강행태관련 특성에 따른 흡연은 음주 정도, 자살 생각률, 우울감 경험률, 스트레스 정도, 아침식사 빈도, 수면 후 피로회복 정도, 주관적 건강 인지 정도에서 유의한 차이가 있다(p<0.001). 남학생의 흡연가능성은 가족구성원 흡연자가 1명일 때보다 가족구성원 흡연자가 2명이상일 때 더 높다(p<0.001). 본 연구의 의의는 남학생 흡연이 가족구성원 흡연상태에 따라 영향을 받는다는 것을 확인하였으며 이러한 연구결과는 청소년 흡연의 예방 및 금연사업을 구성할 때 가족 흡연자의 금연 사업을 병행하여 설계한다면 좋은 효과를 거둘 수 있음을 시사한다.

• 한국산학기술학회논문지
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• 제15권9호
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• pp.5683-5692
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• 2014

본 연구는 결혼이주여성의 한국어 능력, 건강증진행위, 건강상태 간의 상관관계를 분석하기 위해 결혼이주여성 148명을 대상으로 2013년 9월~12월까지 4개월간 자료를 수집하였다. 일반적 특성, 한국어 능력, 건강증진행위(흡연, 음주, 운동, 영양), 정서적 건강상태(스트레스, 결혼생활만족도)는 구조화된 자가 기입식 설문지를, 신체 건강상태(혈당, 총콜레스테롤, 중성지방, 혈색소농도, 헤마토크릿, 체질량지수)는 건강검진 결과를 활용하였다. 연구결과 유질환자와 무질환자 간에 한국어 능력 중 읽기능력, 음주습관, 총콜레스테롤, 체질량지수가 유의하게 차이가 있었다. 결혼이주여성의 한국어 능력과 건강상태간의 상관관계를 분석한 결과, 총콜레스테롤과 중성지방 간에 정상관관계가 있었으며, 헤모글로빈 농도와 총콜레스테롤, 중성지방, 체질량지수와 역상관관계가 있었다. 한국어 능력과 스트레스 간에도 역상관관계가 있었다. 이와 같은 결과를 근거로 결혼이주여성의 질병 발생률을 낮추기 위해서는 결혼이주여성의 음주율, 총콜레스테롤과 체질량 지수를 감소시킬 수 있는 프로그램과 함께 한국어로 된 건강정보 이해력을 증진시킬 수 있는 프로그램을 개발하여 실시할 것을 제안한다.

• 대한화장품학회:학술대회논문집
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• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
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• pp.13-34
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• 2003

Fructose-1, 6-diphosphate (FOP), a glycolytic metabolite is reported to ameliorate inflammation and inhibit the nitric oxide production in murine macrophages stimulated with endotoxin. It is also reported that FOP has cytoprotective effects against hypoxia or ischemia/reperfusion injury in brain and heart. In this study, we examined whether FDP has protective effects on UV-induced oxidative damage in skin cell culture system and human skin in vivo. FDP had a protective role in UVB-induced LDH release and ROS accumulation in HaCaT although it did not show direct radical scavenging effect in the experiment using 1, 1-diphenyl-2-picrylhydrazyl (DPPH). FDP also preserved cellular GSH content after UV irradiation in HaCaT and normal human fibroblast culture system. Cellular oxidative stress induces multiple downstream signaling pathways that regulate expression of multiple gene including MMP-1 and collagen, we examined the effects of FDP on UV-induced alteration of these protein expression in fibroblast culture and human skin in vivo. The increased MMP-1 expression in fibroblast and human skin by UV irradiation was significantly decreased by FDP. FDP also prevented the UV-induced decrease of collagen expression in fibroblast and human skin. Moreover, the decreasing the intracellular levels of reducing equivalents in human fibroblast by glutathione (GSH) depletion lowered the UVA dose threshold for reduction of procollagen expression, indicating that the differences of glutathione contents define the susceptibility of fibroblasts towards UV-induced reduction of procollagen expression. FDP also preserved cellular GSH content after UV irradiation, indicating that FDP has protective effects on UV-induced reduction of procollagen expression, which are possibly through maintaining intracellular reducing equivalent. Based on these premises, we examined the effect of daily use of a moisturizer containing FDP on facial wrinkle in comparison with vehicle moisturizer lacking FDP. In the clinical study, FDP significantly decreased facial wrinkle compared with vehicle alone after 6 months of use. Our results suggest that FDP has anti-aging effects in skin by increasing cellular antioxidant system and preventing oxidative signal and inflammatory reaction. Therefore FDP may be useful anti-aging agent for cosmetic purpose.

• 대한공업교육학회지
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• 제36권1호
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• pp.115-130
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• 2011

수중을 운동하는 원통형 구조물의 끝단에서 앞쪽으로 전달되는 구조 소음은 배열 센서의 감도에 많은 영향을 미치게 된다. 이러한 전달 소음을 효과적으로 차단하고자 두 개의 소음차단 링을 직경이 500mm이고 길이가 840mm인 구조물의 원통 끝면에서 120mm, 240mm 지점에 각각 설치하고 소음 주파수별 저감 특성을 분석하였다. 두 개의 소음차단 링을 설치한 결과 센서가 받는 최대 응력이 약 10.1 % 감소함을 알 수 있었다. 외부 소음 주파수를 100Hz에서 6kHz까지 입력하고 두 개의 소음차단 링의 존재 유무에 따른 소음저감 예측곡선을 6차 다항식을 이용하여 예측하였는데 주파수 4kHz~6kHz 대역에서는 소음차단 링의 설치로 인하여 약 20dB 내외의 소음 저감 효과가 있음을 알 수 있었다. 외부 음원 주파수가 각각 200Hz, 500Hz, 900Hz 일 때 원통형 구조물의 표면에 발생하는 음압 레벨을 수치 해석한 결과 두 개의 소음 차단 링이 설치된 후에는 최고음압을 나타내는 부위가 점차 원통 우측 끝면으로 옮겨감을 알 수 있었다. 곡면 배열센서의 설치 특성은 원통 주위를 따라 배열되는 것을 생각한다면 이러한 형태의 소음차단 링은 매우 효과적으로 소음 감소를 이룰 수 있을 것으로 판단된다.

• 성인간호학회지
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• 제12권2호
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• pp.296-310
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• 2000

During the past 10 years, concern for community people's health has increased together with the changes. Public health policies and studies for community people's health, however, have influenced those in childmaternal health care to want more general coverage and studies of health and wellness. Particularly, the study of community people's health in the extent an island area is almost rare as that personal and the material benefits in this area are lacking of community people's work is large, and the basic elements of living, such as diet and elimination, are irregular due to the schedule of the tide. Thus, there are many potential health problems. In this regard, the study attempted to understand the health problems of island community people and to provide a basis for developing health promotion and health education programs. In collecting data for the study, face to face interviews were made through a structured questionnaire from October 1 to December 30, 1996. Collected data were analyzed with the SAS statistics program, descriptive statistics, t-test and ANOVA. Subjects' health status was examined by classifying into such categories as their health perception, complaints of health problem, related lifestyle, psychosocial health staus, the result of examination is as follows; 1. For subjects' health perception, 26.9% of the subject answered not sick, but not so healthy'; 30.9% thought they were healthy, while 22.9% answered that they were not healthy. 2. For the health problem complaints many complained of pains in their muscles and skeletal system, especially knee joint pain. Women's health problems related with breast and the reproductive system included 52.3% of cases doing breast self examination, while 56.55% received the cervical cancer screening test. In men's health problems, 44.2% of subjects answered that they have moderate to severe BPH(Benign Prostatic Hypertrophy) symptom. 3. There were statistically a significant difference in the degree of physical health according to marital status(p=0.0028), occupation(p=0.0442), income(p=0.0357). 4. For stress status, 17.2% was to need the intervention, 50.2% was to need observation. 5. The mean score of self-esteem was 27.7 showing a relatively high score. 6. For the rate of smoking, 37.7% used to smoke, while 28% used to take alcohol. 7. The rate of substance abuse was 45.9% of subjects. 8. Most of subjects' health behaviors included most of the acupuncture (52%). 9. The rate of subjects receiving comprehensive medical testing was 34.36% while 34.78% did after care managing behavior. 10. For the obesity grade, 53% is normal weight, low-weight 32.8%, obesity 33%. 11. For nutrition status, 78.7% illy balanced to need intervention of nutritional education. 12. For 78.7% of subjects, muscle strength and 40.7% of stretching were not good enough to need health education on physical exercises. Therefore, based on the results, appropriate health education programs need to be developed to promote health of community people on an island.

• 한국구조물진단유지관리공학회 논문집
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• 제20권3호
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• pp.10-17
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• 2016

본 연구는 단경간 교량의 정적하중입력/변위출력관계를 이용한 새로운 교량 유한요소모델 개선 방법을 제안하였고, 실내 모형교량 실험을 통해 검증하였다. 기존의 유한요소모델개선기법은 실험으로부터 얻어진 모드계수와 유한요소모델로부터 예측된 모드계수가 유사해지도록 유한요소모델을 개선하는데, 이 과정에서 구조계의 질량행렬에 대한 가정을 필요로 한다. 제안된 기법은 질량행렬을 가정하지 않고, 오히려 질량행렬 추정을 가능하게 하는 장점을 가진다. 제안된 기법은 두 단계로 구성된다. 첫째, 정적 하중입력-변위응답으로부터 강성행렬을 개선하고, 둘째, 실측된 고유진동수를 이용하여 질량행렬을 개선한다. 실험검증을 위하여 실내 모형교량을 제작하였고, 제안된 기법을 이용하여 모형교량의 탄성계수를 추정하였으며, Universal Testing Machine으로 부터 얻어진 탄성계수와 비교하였다. 또한 기존의 유한요소모델개선기법으로 추정된 탄성계수와 비교하였다. 실험의 결과들로부터 제안된 기법이 합리적으로 탄성계수와 질량밀도를 추정하는 것이 관찰되었고, 기존의 유한요소모델개선기법은 고차모드를 사용했을 때 상대적으로 큰 오차를 주는 것이 관찰되었다. 추가적으로 유한요소모델링 오차에 대하여 토의하였다.

• Journal of Microbiology and Biotechnology
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• 제18권1호
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• pp.15-22
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• 2008

Four series (S, M, R, and W) of Alternaria longipes isolates were obtained based on consecutive selection with Dimethachlon (Dim) and ultraviolet irradiation. These isolates were then characterized according to their tolerance to Dim, sensitivity to osmotic stress, and phenotypic properties. All the selected Dim-resistant isolates showed a higher osmosensitivity than the parental strains, and the last generation was more resistant than the first generation in the M, R, and W series. In addition, the changes in the Dim resistance and osmotic sensitivity were not found to be directly correlated, and no distinct morphologic characteristics were found among the resistant and sensitive isolates, with the exception of the resistant isolate K-11. Thus, to investigate the molecular basis of the fungicide resistance, a group III two-component histidine kinase (HK) gene, AlHK1, was cloned from nineteen A. longipes isolates. AlHK1p was found to be comprised of a six 92-amino-acid repeat domain (AARD), HK domain, and response regulator domain, similar to the Os-1p from Neurospora crassa. A comparison of the nucleotide sequences of the AlHK1 gene from the Dim-sensitive and -resistant isolates revealed that all the resistant isolates contained a single-point mutation in the AARD of AlHK1p, with the exception of isolate K-11, where the AlHK1p contained a deletion of 107 amino acids. Moreover, the AlHK1p mutations in the isolates of each respective series involved the same amino acid substitution at the same site, although the resistance levels differed significantly in each series. Therefore, these findings suggested that a mutation in the AARD of AlHK1p was not the sole factor responsible for A. longipes resistance to dicarboximide fungicides.

• 동의생리병리학회지
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• 제28권6호
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• pp.674-682
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• 2014

The purpose of this study was to identify the effect of applying oriental music therapy and reliability of electroencephalogram(EEG) equipment. The study was approved by the critical trial judge committee from ${\bigcirc}{\bigcirc}$(IRB No. 2013-07) university. In order to measure test-retest reliability for 15 subjects, EEG for same participants were measured using same method mentioned above after 2 hours from the first measurement. Same provider implemented to each person at same time. Firstly, EEG was measured for 5 minutes after the subject with attached electrodes sat on chair comfortably for 10 minutes. Then, the subject was given mental stress using the four fundamental arithmetic operations for 5 minutes, and measured EEG for another 5 minutes. After that the subject sat on the chair comfortably listening oriental medicine music therapy for 5 minutes, and EEG was measured for 5 minutes again. There was no side effect regarding music therapy reported. Raw data, which was measured in each step, were converted through FFT(fast fourier transform) and analyzed after divided into certain frequency including ${\alpha}$ wave, ${\beta}$ wave, ${\theta}$ wave, immersion wave, stabilization wave, sef100 wave, and sef95 wave. Data were analyzed using wilcoxon signed rank test, Intraclass correlation coefficient(ICC), repeated measures ANOVA with the SPSS program. In test-retes method, there were significantly differences in ${\alpha}$ wave, ${\beta}$ wave, immersion wave, stability wave, ${\theta}$ wave, sef100 wave, sef95 wave. ICC has shown a high degree of reliability that it was ${\alpha}$ wave .877, ${\beta}$ wave .855, ${\gamma}$ wave .895, immersion wave .897, stability wave .816, ${\theta}$ wave .904, sef100 wave .910, sef95 wave .776. Also, there was a statistically significant difference in ${\alpha}$ wave after applying oriental music therapy. Based on these results, it is considered that average of the channel EEG and application of oriental music therapy would be practiced by increase of sample size using this machine.

• 생명과학회지
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• 제21권3호
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• pp.400-405
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• 2011

Autophagy는 항상성 유지와 스트레스반응을 효율적으로 조정하기 위해 필수적인 세포 내 질적 조절작용이다. 노화가 진행되는 동안 autopahgy에 의한 degradation 효율성 저하와 그로 인한 세포 내 부산물의 축적이 증가하여 결국, 근육의 약화를 초래한다. 그러므로 본 연구의 목적은 골격근에서 운동에 의한 autopahgy 관련 단백질의 변화를 규명하는데 있다. 이를 위해 24마리의 Young 그룹과 Old 그룹을 나누어 각각 대조군(n=6)과 운동군(n=6)으로 배정하였다. 운동은 8주간 주 5회 실시하였고, 트레드밀 속도 16.4 m/min와 경사도 4%로 설정하여 40분간 지속적인 운동을 실시하였다. autopahgy 관련 단백질에 대한 검증 결과 Young 그룹과 비교하여 Old 그룹에서 LC3-1, Beclin-1, Atg7은 모두 유의하게 감소하였다. 그러나 8주간의 규칙적인 운동에 의하여 autophagy 관련 단백질은 증가하는 것으로 나타났다. 따라서 노화에 의해 약화된 autopahgy 기능은 규칙적인 운동에 의해 개선될 수 있을 것으로 사료된다.

• KIEE International Transaction on Systems and Control
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• 제2D권2호
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• pp.78-91
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• 2002

In the thermal power plant, there are six manipulated variables: main steam flow, feedwater flow, fuel flow, air flow, spray flow, and gas recirculation flow. There are five controlled variables: generator output, main steam pressure, main steam temperature, exhaust gas density, and reheater steam temperature. Therefore, the thermal power plant control system is a multinput and output system. In the control system, the main steam temperature is typically regulated by the fuel flow rate and the spray flow rate, and the reheater steam temperature is regulated by the gas recirculation flow rate. However, strict control of the steam temperature must be maintained to avoid thermal stress. Maintaining the steam temperature can be difficult due to heating value variation to the fuel source, time delay changes in the main steam temperature versus changes in fuel flow rate, difficulty of control of the main steam temperature control and the reheater steam temperature control system owing to the dynamic response characteristics of changes in steam temperature and the reheater steam temperature, and the fluctuation of inner fluid water and steam flow rates during the load-following operation. Up to the present time, the Proportional-Integral-Derivative Controller has been used to operate this system. However, it is very difficult to achieve an optimal PID gain with no experience, since the gain of the PID controller has to be manually tuned by trial and error. This paper focuses on the characteristic comparison of the PID controller and the modified 2-DOF PID Controller (Two-Degrees-Freedom Proportional-Integral-Derivative) on the DCS (Distributed Control System). The method is to design an optimal controller that can be operated on the thermal generating plant in Seoul, Korea. The modified 2-DOF PID controller is designed to enable parameters to fit into the thermal plant during disturbances. To attain an optimal control method, transfer function and operating data from start-up, running, and stop procedures of the thermal plant have been acquired. Through this research, the stable range of a 2-DOF parameter for only this system could be found for the start-up procedure and this parameter could be used for the tuning problem. Also, this paper addressed whether an intelligent tuning method based on immune network algorithms can be used effectively in tuning these controllers.