• Herbal Formula Science
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• v.14 no.1
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• pp.184-191
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• 2006

Cold Urticaria and Cholinergic Urticaria are considered to be distinct disorders in which mediator release and hives can be induced by different stimulti. While neither cold Urticaria nor cholinergic Urticaria is rare, it is unusual to see both disorders occurring in the same patient. Also, our case presents atypical urtication to cold exposure. similar to classic cholinergic Urticaria lesions, called ‘cold-induced cholinergic urticaria’. a case of It lives from as usual as cold as ice environment and When entering into the warm place, the patient minute when the urticaria appears cold - induced cholinergic Urticaria it suspects, The sasang constitution which will reach the result which it demonstrates medically it got the effect which considers it reports.

• Journal of Haehwa Medicine
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• v.17 no.2
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• pp.149-153
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• 2008

Objective : Cold Urticaria is a symptom of edema and pruritus that appear when a patient is exposed to the coldness. The effect of Bee-venom Acpuncture Therapy is antiinflammatory, pain-killing, and blood circulation promotion. The aim of this study is to report the effect of Bee-venom Acpuncture Therapy to Cold Urticaria. Methods : The Cold Urticaria patients were treated with Bee-venom Acpuncture Therapy. Result and Conclusion : Edema and Pruritus of Cold Urticaria patient improved after Bee-venom Acpuncture Therapy.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.6 no.1
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• pp.185-189
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• 1993

Urticaria is a common disease and a well known reaction pattern of the skin charaterized by erythema or wheals and edema, that is the results of various cause. Cold urticaria has symptom on condition that patient feeles cold or touches ice and cold water. These symptoms have a tendency to be aggravated in the winter. We report two cases of cold urticaria. The patients are 38-year-old woman and 30-year-old woman with two years and four years history of recurrent urticaria. The patients showed cold urticaria We have experienced good improventment to be treated with acupuncture and herbal medicine by the Oriental Medicines.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.5
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• pp.1133-1140
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• 2003

Clinical feature of the urticaria is characterised by sudden appearance on the certain positions of the body, scarlet or light yellow, enlarging and merging into stretches with scraching. The most common menifestations are burning heat, severe itching, fever, abdominal pain etc. It Is classified on the basis of the color. There are red and white urticaria in the classics of the Oriental medicine. Red urticaria is caused by warm-heat evil on the other hand white urticaria is caused by cold-wetness evil. It is advisable to follow the therapeutic principles of expelling warm-heat and cold-wetness evils, regulating yin-yang.

• Journal of Sasang Constitutional Medicine
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• v.26 no.3
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• pp.304-317
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• 2014

Objectives The purpose of this study was to find out whether there were differences of urticaria's disease aspect between patients classified into Sasang Constitution Types(SCTs) and whether those differences could be associated with Ordinary symptoms. Methods Medical records and questionnaires about 117 patients who visited one Korean medicine hospital due to urticaria were collated and statistically analyzed. Results 1) Ages 20 to 30, women, Soeumin(SE) and patients in conditions of chronic urticaria over 6 weeks were the majority among 117 patients in this study. Food and stress were most chosen as the main cause of urticaria. 2) Soyangin(SY) showed more severe symptoms of urticaria than other SCTs. In particular, the severity of pruritus, distribution of lesions and vulnerability to stress was statistically significant compared to other SCTs(p<0.05). SE expressed urticaria's symptoms at the medium-level of SY's and Taeeumin(TE)'s. TE exhibited relatively weak symptoms but TE only had slightly higher number of patients with angioedema compared to other SCTs. Taeyangin(TY) was only one case so more researches are needed. 3) In dispositional symptoms, SY had low quality of sleep and defecation. SE could not digest oily food well, felt dizzy and cold well, and had cold hands and feet. TE could eat and sweat much and tended to snore well. Conclusions In this study, urticaria had common cause of both stress and food in all SCTs but onset and severity of symptoms were different between SCTs. It could interpreted that these differences between SCTs were associated with ordinary symptoms native to each SCT.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.36 no.4
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• pp.122-144
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• 2023

Objectives : The purpose of this study is to evaluate the effects of herbal medicine treatment in patients with cold urticaria. Methods : We searched randomized controlled trials(RCTs) reporting the effects of herbal medicine for cold urticaria through domestic and international databases from their inception to September 2023. The results were summarized in tables. We assessed the risk of bias in included RCTs through Cochrane risk of bias tool and the data synthesis was conducted through RevMan version 5.4. Results : A total of 12 RCTs were included in this review and all trials compared herbal medicine alone treatment(treatment group) with western medicine alone treatment(control group). The total effective rate(TER) of treatment group was statistically higher than that of control group(RR: 1.49, 95% CI: 1.38 to 1.62, p<0.00001, I²=65%). On the other hand, when comparing except for 1 trial with different evaluation period, the TER of treatment group was statistically higher than that of control group and heterogeneity was very low(RR: 1.36, 95% CI: 1.26 to 1.47, p<0.00001, I²=0%). And when comparing 8 trials using the total symptom score(TSS) change index as an indicator of TER, the TER of treatment group was statistically higher than that of control group and heterogeneity was very low(RR: 1.38, 95% CI: 1.26 to 1.51, p<0.00001, I²=0%). The treatment group showed more statistically significant decrease compared to the control group in TSS(MD: -2.51, 95% CI: -2.63 to -2.40, p<0.00001, I²=99%). The relapse rate of treatment group was statistically lower than that of control group(RR: 0.19, 95% CI: 0.10 to 0.40, p<0.00001, I²=0%). Mild adverse events such as sleepiness, dizziness were reported in control group and gastric discomfort was reported in treatment group. In the risk of bias assessment, many cases were evaluated as 'Unclear risk'. Conclusions : This review found that herbal medicine alone treatment could more effective and safe than western medicine alone treatment for cold urticaria. But further well-designed researches are needed because of heterogeneity between trials and the quality of the included trials.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.17 no.3
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• pp.61-79
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• 2004

Urticaria is a common dermatopathy, coming under "eun-jin(隱疹) in Korean Oriental medicine. We researched sixty-two patients of urticaria who had visited the Dept of Dermatology Oriental medical hospital Dongeui universty from January 2002 to April 2004 and had taken the Oriental herb medicine as Sungmagalguntanggamibang (SGT, 升摩葛根湯加味方) for verification of voluntariness of Korean Oriental medical treatment. In our time, urticaria is tending upwards, consequently the air pollution by industrialization, patronizing of convenience food by simplification of dietary life, stress and an abuse of medicine. Especially in case of chronic urticaria we're under going hardships in elimination of it's symptoms, because it's prognosis is inferior. We inspect the effects of SGT from various viewpoints and meet with following results. Results: 1. AS amount of taking the SGT increase, the effect in taking SGT period and the condition of present time become more satisfactory. 2. As continuous Time of urticaria decrease, the effect in taking SGT period become more satisfactory. 3. Etiology of urticaria is classified into the deficiency both of qi-blood(氣血兩虛), the moisture-heat of spleen-stomach(脾胃濕熱), the heat of blood(血熱), The wind-cold(風寒), The wind-heat(風熱), spleen-stomach accumulated heat(腸胃實熱) ect. The SGT is available in this order. 4. The effect in taking SGT period connects the quality of life of after treatment and the quality of life of after treatment is improved comparing with that of before treatment. The above results demonstrate that SGT effectively suppresses recurrent, pruitus and erythematous urticaria.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.25 no.1
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• pp.55-74
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• 2012

Objective : The purpose of this study is to investigate the skin disease in Sanghanron"傷寒論" and Geumgweyoryak"金匱要略". Methods : We conducted a study on the original text paragraphs of Sanghanron and Geumgweyoryak containing the skin disease and analysis of Woo, Oh, Sung, Zhang, etc. We drew a parallel between skin disease from Sanghanron and Geumgweyoryak and matching diagnoses from western medicine. Results : The results were as follows. 1. In Sanghanron and Geumgweyoryak pruritus was related to psychogenic pruritus and similar to skin disease caused by decrease of sweating, dry skin in cholinergic urticaria, atopic dermatitis and eczema, etc. in western medicine. 2. In Geumgweyoryak ichthyosis was caused by woman's disease, after menopause, chronic disease and malnutrition and related to winter itch and xerotic eczema in western medicine. 3. In Sanghanron Goose bumps, keratosis follicularis, acute and chronic urticaria and cold urticaria were occurred because of poorly managed fever care and side effect of antibiotic. 4. In Geumgweyoryak red face was similar to face flushing and side effects, which is after drug and laser treatment on face, in western medicine. 5. In Geumgweyoryak urticaria was, in a broad sense, skin disease with pruritus and secondary infection resulted from scratch. Skin diseases with pruritus are similar to urticaria, dermatitis herpetiformis, lichen planus, atopic dermatitis, contact dermatitis, psoriasis, nummular eczema, lichen simplex chronicus, prurigo nodularis, neurodermatitis and internal disease with pruritus in western medicine. 6. In Geumgweyoryak spots in the skin were caused by fever and similar to allergic purpura and SLE symptom in western medicine. 7. In Geumgweyoryak bullous disease with yellowish discharge was similar to eczema, pustule, atopic eczema, etc. in western medicine. 8. In Geumgweyoryak repeated inflammation of oral cavity, genitals, eyes and skin was similar to Behcet's disease in western medicine. 9. In Sanghanron and Geumgweyoryak boil was similar to abscess and acute lymphadenitis in western medicine caused by oily foods and infections. 10. In Geumgweyoryak swelling and boil were occurred in a poor health. Damage from metalic material could cause a convulsion and was similar to tetanus in western medicine. Conclusion : We analyzed the original text paragraphs of Sanghanron and Geumgweyoryak and explanations about skin disease. As a results, we found out etiology, pathogenesis, treatments of the skin disease in Sanghanron and Geumgweyoryak. Further we compared with western medicine to develop better understanding of the skin disease.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.1 s.32
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• pp.256-264
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• 2007

Objective : This study describes a case of urticarial drug eruption assumed to be caused by non-steroidal anti- inflammatory drugs (NSAIDs) treated with oriental medicine and acupuncture. Methods : We studied the case of 20-years-old drug eruption patient. The patient complained of urticaria, angioedema, itching and burning sensation after taking NSAIDs. The indications for NSAIDs prescribed were common cold symptom and sore throat. For diagnosis, blood test and urinalysis were done. For treatment, acupuncture and herbal-medicine treatment were applied. Results : The patient of this report were examined for 13 days. The radiological finding was within normal limits. The WBC, neutrophil, lymphocyte and eosinophil level normalized during admission. After 3 days, itching and wheal reaction of whole body disappeared except facial symptom. The angioedema, itching and wheal reaction in the face was almost improved in the 4th day after discharge. Conclusions : We may expect that the oriental medical therapy improves the urticarial drug eruption caused by NSAIDs.

• Natural Product Sciences
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• v.17 no.4
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• pp.303-308
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• 2011

Spirodela polyrrhiza L. Schleid. (Lemnaceae), also known as 'duckweed', is a traditional medicine in Korea. The whole plant is used to treat many diseases, including the common cold, edema, acute nephritis, and urticaria. The present study investigated antinociceptive properties of the EtOAc soluble fraction of S. polyrrhiza (ESP). The antinociceptive activities of ESP were studied using experimental models of pain, including thermal nociception methods, such as the tail immersion test and the hotplate test. Moreover, we studied chemical nociception induced by intraperitoneal acetic acid and subplantar formalin in mice. ESP exhibited dose-dependent antinociceptive activity in both thermal and chemical pain models. In a drug combination test using the opioid receptor antagonist naloxone, diminished analgesic activities of ESP were observed, indicating that the antinociceptive activity of ESP is mediated by opioid receptors.