• Title/Summary/Keyword: Coherence imaging

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3-D OCT Image Reconstruction for Precision Analysis of Rat Eye and Human Molar (쥐 눈과 인간 치아의 정밀한 단층정보 분석을 위한 OCT 3-D 영상 재구성)

  • Jeon, Ji-Hye;Na, Ji-Hoon;Yang, Yoon-Gi;Lee, Byeong-Ha;Lee, Chang-Su
    • The KIPS Transactions:PartB
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    • v.14B no.6
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    • pp.423-430
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    • 2007
  • Optical coherence tomography(OCT) is a high resolution imaging system which can image the cross section of microscopic organs in a living tissue with about $1{\mu}m$ resolution. In this paper, we implement OCT system and acquire 2-D images of rat eye and human molar samples especially in the field of opthalmology and dentistry. In terms of 2-D images, we reconstruct 3-D OCT images which give us another inner structural information of target objects. OPEN-GL reduces the 3-D processing time 10 times less than MATLAB.

Comb-spacing-swept Source Using Differential Polarization Delay Line for Interferometric 3-dimensional Imaging

  • Park, Sang Min;Park, So Young;Kim, Chang-Seok
    • Current Optics and Photonics
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    • v.3 no.1
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    • pp.16-21
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    • 2019
  • We present a broad-bandwidth comb-spacing-swept source (CSWS) based on a differential polarization delay line (DPDL) for interferometric three-dimensional (3D) imaging. The comb spacing of the CSWS is repeatedly swept by the tunable DPDL in the multiwavelength source to provide depth-scanning optical coherence tomography (OCT). As the polarization differential delay of the DPDL is tuned from 5 to 15 ps, the comb spacing along the wavelength continuously varies from 1.6 to 0.53 nm, respectively. The wavelength range of various semiconductor optical amplifiers and the cavity feedback ratio of the tunable fiber coupler are experimentally selected to obtain optimal conditions for a broader 3-dB bandwidth of the multiwavelength spectrum and thus provide a higher axial resolution of $35{\mu}m$ in interferometric OCT imaging. The proposed CSWS-OCT has a simple imaging interferometer configuration without reference-path scanning and a simple imaging process without the complex Fourier transform. 3D surface images of a via-hole structure on a printed circuit board and the top surface of a coin were acquired.

Statistical Characteristics of Polarization - Sensitive Optical Coherence Tomography for Tissue Imaging

  • Oh, Jung-Taek;Kim, Beop-Min;Kim, Seung-Woo
    • Journal of the Optical Society of Korea
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    • v.7 no.4
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    • pp.211-215
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    • 2003
  • Statistical characteristics of the backscattered light from turbid tissues obtained by polarizationsensitive optical coherence tomography are investigated. The amplitude of the backscattered light is found to faithfully follow the Rayleigh distribution predicted by the scattering theory of electromagnetic waves in random media. The probability density function of the phase difference between the two orthogonal polarization components of the backscattered light is explicitly derived and then verified in comparison with the experimental data measured from in-vitro tissues of porcine ligament.

Rapid Defect Inspection of Display Device with Optical Spatial Filtering

  • Yoon, Dong-Seon;Kim, Seung-Woo
    • International Journal of Precision Engineering and Manufacturing
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    • v.1 no.1
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    • pp.56-61
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    • 2000
  • We present a fast inspection method of machine vision for in-line quality assurance of liquid crystal displays(LCD) and plasma display panels(PDP). The method incorporates an optical spatial filter in the Fourier plane of the imaging optics to block the normal periodic pattern, extracting only defects real time without relying on intensive software image process. Special emphasis is on designing a collimated white light source to provide high degree of spatial coherence for effective real time Fourier transform. At the same time, a low level of temporal coherence is attained to improve defect detection capabilities by avoiding undesirable coherent noises. Experimental results show that the proposed inspection method offers a detection accuracy of 15% tolerance, which is sufficient for industrial applications.

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Current and Future Technologies for a Gastrointestinal Endoscopy (소화기 내시경의 기술 현황과 전망)

  • Chee, Young-Joon;Woo, Jih-Wan
    • Journal of Biomedical Engineering Research
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    • v.31 no.5
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    • pp.335-343
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    • 2010
  • This article presents a review of technologies for an endoscope. The classification according to the clinical applications and the imaging modalities are summarized. The major parts are focused on describing the gastrointestinal endoscope's structures and mechanisms. The details of the image enhanced endoscopic techniques, such as NBI (narrow band imaging), OCT (optical coherence tomography), and EUS (endoscopic ultrasound), are also explained. Finally, the trend of NOTES (natural orifice transluminal endoscopic surgery) which is new fusion technology in the field of endoscopic diagnosis and surgery is introduced.

Ghost Imaging with Different Speckle Sizes of Thermal Light

  • Jue, Wang;Renlong, Yu;Yu, Xin;Yanming, Shao;Yanru, Chen;Qi, Zhao
    • Journal of the Optical Society of Korea
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    • v.20 no.1
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    • pp.8-12
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    • 2016
  • In this paper, we theoretically and experimentally analyze the impact of speckle size of pseudo-thermal light source on ghost imaging. A larger size of speckle can bring improvements in SNR and visibility. At the same time, the edge blur of the retrieved image will become more serious. We also present a setup which can mitigate the edge blur of larger speckle while maintaining the advantages of higher SNR and visibility by changing the speckle size of the object beam with a concave lens.

Utilizing Optical Phantoms for Biomedical-optics Technology: Recent Advances and Challenges

  • Ik Hwan Kwon;Hoon-Sup Kim;Do Yeon Kim;Hyun-Ji Lee;Sang-Won Lee
    • Current Optics and Photonics
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    • v.8 no.4
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    • pp.327-344
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    • 2024
  • Optical phantoms are essential in optical imaging and measurement instruments for performance evaluation, calibration, and quality control. They enable precise measurement of image resolution, accuracy, sensitivity, and contrast, which are crucial for both research and clinical diagnostics. This paper reviews the recent advancements and challenges in phantoms for optical coherence tomography, photoacoustic imaging, digital holographic microscopy, optical diffraction tomography, and oximetry tools. We explore the fundamental principles of each technology, the key factors in phantom development, and the evaluation criteria. Additionally, we discuss the application of phantoms used for enhancing optical-image quality. This investigation includes the development of realistic biological and clinical tissue-mimicking phantoms, emphasizing their role in improving the accuracy and reliability of optical imaging and measurement instruments in biomedical and clinical research.

Simple Spectral Calibration Method and Its Application Using an Index Array for Swept Source Optical Coherence Tomography

  • Jung, Un-Sang;Cho, Nam-Hyun;Kim, Su-Hwan;Jeong, Hyo-Sang;Kim, Jee-Hyun;Ahn, Yeh-Chan
    • Journal of the Optical Society of Korea
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    • v.15 no.4
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    • pp.386-393
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    • 2011
  • In this study, we report an effective k-domain linearization method with a pre-calibrated indexed look-up table. The method minimizes k-domain nonlinear characteristics of a swept source optical coherence tomography (SS-OCT) system by using two arrays, a sample position shift index and an intensity compensation array. Two arrays are generated from an interference pattern acquired by connecting a Fabry-Perot interferometer (FPI) and an optical spectrum analyzer (OSA) to the system. At real time imaging, the sample position is modified by location movement and intensity compensation with two arrays for linearity of wavenumber. As a result of evaluating point spread functions (PSFs), the signal to noise ratio (SNR) is increased by 9.7 dB. When applied to infrared (IR) sensing card imaging, the SNR is increased by 1.29 dB and the contrast noise ratio (CNR) value is increased by 1.44. The time required for the linearization and intensity compensation is 30 ms for a multi thread method using a central processing unit (CPU) compared to 0.8 ms for compute unified device architecture (CUDA) processing using a graphics processing unit (GPU). We verified that our linearization method is appropriate for applying real time imaging of SS-OCT.

Study on application to the field of dentistry using optical coherence tomography (OCT) (치의학 분야에 대한 광간섭 단층영상기기(optical coherence tomography)의 적용 가능성 고찰)

  • Pyo, Se-Wook;Lim, Young-Joon;Lee, Won-Jin;Lee, Jun-Jae
    • The Journal of Korean Academy of Prosthodontics
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    • v.55 no.1
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    • pp.100-110
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    • 2017
  • Purpose: This paper describes the basic principles and the feasibility of the field of dental diagnosis of optical coherence tomography (OCT) used in diverse field of medical diagnosis. Materials and methods: In this review, the research data of OCT were searched from PubMed, medical journal and related papers. Results: Generally, OCT is noninvasive and is possible to secure an excellent spatial resolution and real-time images of biological microstructure. Conclusion: This review discusses not only the basic principles of operation, types, advantages, disadvantages of OCT but also the future applications of OCT technology and their potential in the field of dental diagnosis.

Ex vivo High-resolution Optical Coherence Tomography (OCT) Imaging of Pleural Reaction after Pleurodesis Using Talc

  • Ahn, Yeh-Chan;Oak, Chulho;Park, Jung-Eun;Jung, Min-Jung;Kim, Jae-Hun;Lee, Hae-Young;Kim, Sung Won;Park, Eun-Kee;Jung, Maan Hong
    • Journal of the Optical Society of Korea
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    • v.20 no.5
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    • pp.607-613
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    • 2016
  • The pleura is known as an end target organ of exposure to toxic environmental materials such as fine particulate matter and asbestos. Moreover, long-term exposure to hazardous materials can eventually lead to fatal lung disease such as diffuse pleural fibrosis or mesothelioma. Chest computed tomography (CT) and ultrasound are gold standard imaging modalities for detection of advanced pleural disease. However, a diagnostic tool for early detection of pleural reaction has not been developed yet due to difficulties in imaging ultra-fine structure of the pleura. Optical coherence tomography (OCT), which provides cross-sectional images of micro tissue structures at a resolution of 2-10 μm, can image the mesothelium with a thickness of ~100 μm and therefore enables investigation of the early pleural reaction. In this study, we induced the early pleural reaction according to a time sequence after pleurodesis using talc, which has been widely used in the clinical field. The pleural reaction in talc grouped according to the time sequence (1st, 2nd, 4th weeks) showed a significant thickening (average thickness: 45 ± 7.5 μm, 80 ± 10.7 μm, 90 ± 12.5 μm), while the pleural reaction in sham and normal groups showed pleural change from normal to minimal thickening (average thickness: 16 ± 5.5 μm, 17 ± 4.5 μm, 15 ± 6.5 μm, and 12 ± 7.5 μm, 13 ± 2.5 μm, 12 ± 3.5 μm). The measurement of pleural reaction by pathologic examinations was well-matched with the measurement by OCT images. This is the first study for measuring the thickness of pleural reactions using a biophotonic modality such as OCT. Our results showed that OCT can be useful for evaluating the early pleural reaction.