• The Korean Journal of Rehabilitation Nursing
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• v.11 no.2
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• pp.90-98
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• 2008

Purpose: The purpose of this study was to examine the cognitive function and degree of dementia patient by doing clock drawing test and to explore the relationship among other dementia screening test. Method: The study subjects were 94 dementia in patients department. The data was collected by face to face interview by clinical psychologist from January 2007 to February 2008. The tools were Clock Drawing Test, K-MMSE, K-3MS and CDR Scale. Results: 1) The average score of CDT was 5.13 (2.54), of K-MMSE was 20.53 (4.85), of K-3MS was 61.66 (16.46), and of CDR was 1.2 (.72), those scores showed dementia. 2) There was a statistically the significant difference in CDT (F=2.83, p=.043) and CDR (F=2.00, p=.008) by age. CDT has shown the differences by gender (t=-2.42, p=.018) and education (F=7.66, p=.000). 3) There were significant relationships between CDT and K-MMSE (r=-.294. p=.004), K-3MS (r=-.335, p=.001), and CDR (r=.286, p=.008). Conclusion: It is believed that using CDT which measures the visuospatial ability of dementia patients and K-MMSE which assesses an ability of language and orientation and K-3MS at the same time helps examining the beginning and the progressive degree of dementia more easily and objectively.

• Physical Therapy Rehabilitation Science
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• v.7 no.3
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• pp.114-118
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• 2018

Objective: The left and right sides of the brain has different roles. This study investigated the differences in cognitive driving ability between stroke survivors with damage to the left brain and right brain. Therefore, the purpose of this study was to compare the driving cognitive ability of left and right hemispheric drivers following stroke. Design: Cross-sectional study. Methods: The Stroke Drivers' Screening Assessment (SDSA) from the UK was translated to the Korean Stroke Drivers' Screening Assessment (K-SDSA) to meet the specific traffic environments of Korea. The SDSA is composed of 4 tasks :1) a dot cancellation task that measures concentration and visuospatial abilities necessary for driving, 2) a directional matrix task to measure spatio-temporal executive function required for driving, 3) a compass matrix task to measure accurate direction determination ability required for driving, and 4) recognition of traffic signs and reasoning ability to understanding traffic situation. The SDSA assessment time is about 30 minutes. The K-SDSA was used to compare the cognitive driving abilities between 15 stroke survivors with left and 15 stroke survivors with right brain damage. Results: There were significant differences between the persons with stroke patients with left brain lesions (right hemiplegia) compared to the persons with stroke with right brain lesions (left hemiplegia) (p<0.05). It was found that the cognitive driving ability of those with right brain damage was lower than that of the group of left brain damage. Conclusions: This research investigated the driving cognitive ability of persons with stroke. The therapists can use this information as basis for the driving test and training purposes. It could also be used as a basis to understanding if the cognitive ability of not only stroke survivors but also those with brain damage is adequate to actually drive.

• Korean Journal of Adult Nursing
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• v.24 no.2
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• pp.171-182
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• 2012

Purpose: This study aimed to identify depression and its predictors among Korean community-dwelling elderly with mild cognitive impairment. Methods: Secondary data analyses of the data collected by the "Study on tailored integration program for reinforcing cognitive and physical function of the frail elderly. The study used data from one-to-one interviews using structured questionnaires. The subjects were 346 community-dwelling elderly who visited a healthcare center in Seoul, Korea. A descriptive correlational study design was utilized to explore depression and its predictors including physical factors and psychosocial factors among the elderly with mild cognitive impairment. Data were analyzed using t-test, Pearson's correlation, and hierarchical regression. Results: Mean score of depression was within normal limit $11.61{\pm}6.69$. Somatic symptoms, negative life events (severity), social support were shown as significant predictors of depression. The most influential predictor for depression was somatic symptoms (${\beta}$=.340, $p$ <.001). Conclusion: To prevent and relieve depression in the elderly with mild cognitive impairment, nursing intervention strategies which consider well-balanced physical and psychosocial aspects are needed. In particular, a specific nursing intervention strategy is required to improve physical health of the elderly with mild cognitive impairment.

• Korean Journal of Occupational Health Nursing
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• v.23 no.4
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• pp.197-207
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• 2014

Purpose: The purpose of this study was to investigate the status and characteristics of visiting nurses' management for elders with cognitive impairment living in a community focused on health centers in a metropolitan city and five medium-sized cities. Methods: Data were collected from 47 visiting nurses working in a metropolitan city and 47 visiting nurses working in five medium-sized cities from November to December 2012. Results: There were no statistically significant differences in knowledge, attitudes, and nursing behaviors of cognitive impairment between two groups (F=2.13, p=.148; F=3.64, p=.060; F=0.28, p=.595). Among the elders referred to a physician in a metropolitan city by visiting nurses, 42.4% were diagnosed as mild cognitive impairment and 15.2% were diagnosed as severe dementia. The major intervention programs which visiting nurses currently applied for elders were medication and exercise intervention programs, and the intervention programs which they would want to apply in the future were playing, music and recall intervention programs. Conclusion: The cognitive impairment screening test can be done effectively by visiting nurses. This study also suggests to develop various kinds of intervention programs to improve cognitive function for elders living in a community.

• 한국노년학
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• v.30 no.1
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• pp.81-91
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• 2010

The purpose of this study was to test a validity and reliability of Cognitive Performance Scale(CPS), a cognitive measure generated from 5 items(comatose status, decision making, short-term memory, making self understood, and eating). Method: 393 patients in 2 hospitals for the elderly with dementia were measured with CPS by two nurses independently. The inter-rater agreement was tested by comparing two scores. The CPS score was compared with GDS, which was measured by doctors and nurses, and MMSE score which was drawn from the claim data of Health Insurance Review & Assessment Service. Result: The correlation coefficient between CPS and GDS was 0.742(p<0.0001), CPS and MMSE was -0.794(p<0.0001). The Cronbach's coefficient alpha of CPS was 0.742, Kappa value was 0.772~1.000. The CPS showed high validity and reliability in long term care hospitals of Korea.

• Fisheries and Aquatic Sciences
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• v.25 no.8
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• pp.450-461
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• 2022

A randomized, double-blind, and placebo-controlled clinical study was used to determine the cognitive functions related to working memory (WM) and antioxidant properties of fermented Laminaria japonica (FLJ) on healthy volunteers. Eighty participants were divided into a placebo group (n = 40) and FLJ group (n = 40) that received FLJ (1.5 g/day) for 6 weeks. Memory-related blood indices (brain-derived neurotrophic factor, BDNF; angiotensin-converting enzyme; human growth hormone, HGH; insulin-like growth factor-1, IGF-1) and antioxidant function-related indices (catalase, CAT; malondialdehyde, MDA; 8-oxo-2'-deoxyguanosine, 8-oxo-dG; thiobarbituric acid reactive substances, TBARS) were determined before and after the trial. In addition, standardized cognitive tests were conducted using the Cambridge Neuropsychological Test Automated Batteries. Furthermore, the Korean Wechsler Adult Intelligence Scale (K-WAIS)-IV, and the Korean version of the Montreal Cognitive Assessment (MoCA-K) were used to assess the pre and post intake changes on WM-related properties. According to the results, FLJ significantly increased the level of CAT, BDNF, HGH, and IGF-1. FLJ reduced the level of TBARS, MDA, and 8-oxo-dG in serum. Furthermore, FLJ improved physical activities related to cognitive functions such as K-WAIS-IV, MoCA-K, Paired Associates Learning, and Spatial Working Memory compared to the placebo group. Our results suggest that FLJ is a potential candidate to develop functional materials reflecting its capability to induce antioxidant mechanisms together with WM-related indices.

• Therapeutic Science for Rehabilitation
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• v.4 no.2
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• pp.73-83
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• 2015

Objective: The purpose of this study was to examine the effect of the Spaced Retrieval Training (SRT) with Errorless learning on the elderly with Mild Cognitive Impairment (MCI)'s memory, Instrumental Activities Daily Living, Depression symptom. Methods: A single subject experimental research with ABA design was conducted in this study on the 78-years-old person who was enrolled in day-care center. The total experimental sessions were 16 which composed of 3 sessions for baseline, 10 sessions for intervention and 3 sessions for second baseline. K-Auditory Verbal Learning Test (K-AVLT) was measured for the memory each session. For the measurement of cognitive function, IADL, depression Symptom, Korean version of Montreal Cognitive Assessment (MoCA-K), Philadelphia Geriatric Center Instrumental Activities Daily Living (PGC IADL), Geriatric Depression Scale Korean Version (GDS-K) was measured at pre-post test. Results: Memory at the phase B was improved than Phase A. At the phase B, the scores trend was ascending, but after the intervention at the phase A', the scores trend was descending. The scores of MoCA-K were improved, PGC IADL were maintained, GDS-K were decreased. Conclusion: This results support the evidence of the SRT with EL on the elderly with MCI in the clinical setting. In the future, the correlation researches about MCI's memory and other functional factors will be needed for effective occupational therapy service.

• The Journal of the Korea Contents Association
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• v.9 no.2
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• pp.309-317
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• 2009

This study was to investigate the effects of restoring cognition function and neurotrophic factor in the hippocampus according to memory and learning training in rats affected by brain injury. Brain injury was induced in Sprague-Dawley rats(36 rats) through middle cerebral artery occlusion(MCAo). And then experiment groups were randomly divided into three groups; Group I: Brain injury induction(n=12), Group II: the application for treadmill training after brain injury induction(n=12), Group III: the application for memory and learning training after brain injury induction(n=12). Morris water maze acquisition test and retention test were performed to test cognitive function. And the histological examination was also observed through the immunohistochemistric response of BDNF(brain-derived neurotrophic factor) in the hippocampus. For Morris water maze acquisition test, there were significant interactions among the groups with the time(p<.001). The time to find the circular platform in Group III was more shortened than in Group I, II on the 9th, 10th, 11th and 12th day. For Morris water maze retention test, there were significant differences among the groups(p<.001). The time to dwell on quadrant circular platform in Group III on the 13th day was the longest compared with other groups. And as the result of observing the immunohistochemistric response of BDNF in the hippocampus CA1, the response of immunoreactive positive in Group III on the 7th day increased more than that of Group I, II. These results suggested that the memory and learning training in rats with brain injury has a more significant impact on restoring cognitive function via the changes of neurotropic factor expression and synaptic neuroplasticity.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.2
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• pp.23-33
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• 2021

Purpose : This study aimed to investigate the effects of dual-task training according to the variability of the walking environment on balance, gait, and function in patients with stroke. Methods : Twenty-five patients with stroke were randomly assigned to experimental group I (n=12) and experimental group II (n=13). Experimental group I and II performed obstacle and non-obstacle walking training, respectively, along with cognitive tasks for 21 minutes per session, 3 times a week for 6 weeks. Both groups received additional general physical therapy for 30 minutes per session. The functional reach test (FRT), gait analyzer (G-Walk), and functional independence measure (FIM) were used to evaluate balance, gait and function of pre- and post-interventions, respectively, while gait cadence, gait velocity, and stride length were evaluated using a gait analyzer. Results : In the within-group comparison of FRT, all the two groups showed significant post-intervention improvements (p<.05). In within-group comparison of gait cadence, all the two groups showed significant post-intervention improvements (p<.05). In within-group comparison of gait velocity, all the two groups showed significant post-intervention improvements (p<.05). In within-group comparison of stride length, experimental group I showed significant post-intervention improvements (p<.05), while experimental group II did not show significant post-intervention improvements (p>.05). In within-group comparison of FIM scores, experimental group I showed significant post-intervention improvements (p<.05), while experimental group II did not show significant post-intervention improvements (p>.05). There was a significant difference in the change of FIM scores pre- and post-intervention (p<.05) in the between-group comparison. Conclusion : The results of this study show that dual-task training with cognitive tasks and walking training can improve the balance, gait and function of patients with stroke, and obstacle walking training is effective for improving functions including activities of daily living compared to non-obstacle walking training.

• Speech Sciences
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• v.15 no.2
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• pp.111-118
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• 2008

We identified the characteristic impairmants of linguistic semantic memory in patients with prodromal Alzheimer's disease(AD) and mild AD. To elucidate the earliest changes of semantic language function in subjects with AD, performances on confrontation naming test and verbal fluency task were compared among patients with AD patients (n=20), mild AD patients (n=27) and healthy elderly controls (n=20). Tasks in this study included the confrontation naming test of Test of Lexical Processing in Aphasia(TLPA/Japanese) and one-minute verbal fluency task (semantic/ phonetic categories). The results were as follows: 1) Performances of the prodromal AD group showed the comparable to those of the control group on the confrontation naming test, 2) In the semantic/phonetic verbal fluency tasks, the performances of the control group were better than those of the prodromal AD and mild AD groups, but no significant differences were shown between the prodromal AD and the mild AD group.