• 한국임상보건과학회지
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• 제8권2호
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• pp.1426-1435
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• 2020

Objective: This study aims to develop CFT, a screening test for dementia that can be conducted on patients with mild cognitive impairment or early dementia. Methods: This study was conducted on therapists working at occupational therapy hospital in Gyeongsangnam-do. The data collection period is two months from July to September 2020, and the research participants were briefed on the purpose, significance, and anonymity of the research in consideration of ethical issues. A total of 33 copies of the data were finally analyzed, excluding those containing insufficient answers and errors, by distributing 40 copies of the data. SPSS Data Access pack 8.0 was used for data analysis, Cronbach's α value was evaluated for internal consistency reliability of each item, and Pearson Correlation coeffient between the lower scales of the assessment tool was measured. Results: The Cronbach's α value of the CFT was shown as .892 and the reliability of the assessment paper was shown to be quite high. The Cronbach's α value for each item in the cognitive assessment tool was the highest at .899 in the subtraction item, with exercise control (mook Chi Pa) at 888, visual memory, plus .887. The correlation of each item of cognitive assessment tools was found to be most correlated with the number of sustained concentrates and word2 to .934; in the stop word-numeric item and visual memory to be .85; and in the addition to the auditory memory item .739. Conclusion: Therefore, this study developed cognitive evaluation tools that can distinguish the diversity and cognitive level of screening tests and clarify standards, which are different from the existing dementia screening tools in Korea. Furthermore, the cognitive assessment tools of this study can be verified by applying them to patients with mild cognitive impairment and early dementia, and the criteria for generalization can be established.

• 스트레스연구
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• 제26권4호
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• pp.259-267
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• 2018

본 연구는 독거노인의 인지기능과 삶의 만족도에 영향을 미치는 위험요인을 탐색하고자 하였다. 전국표본추출로 실시된 2014년도 노인실태조사 원시자료 중에서 만 65세 이상인 독거노인 2,449명의 자료를 분석하였다. 인지기능의 위험요인은 고령과 사별경험, 무학력, 운동 안함, 낮은 사회문화 활동만족도로 확인되었다. 삶의 만족도 위험요인은 이혼/미혼/별거경험, 무학력, 미취업, 부정적 건강평가와 우울진단, 운동 안함, 정서적 학대, 경제적 학대, 재정적 방임 경험과 낮은 인지기능 수준으로 확인되었다. 이는 고령의 사별한 독거노인 대상의 적극적인 인지기능 검사 및 강화 프로그램, 사회문화활동 참여를 위한 네트워킹, 우울 예방과 운동 및 건강증진 프로그램, 노인학대 예방을 위한 사회적 노력이 필요함을 시사해준다.

• 디지털융복합연구
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• 제18권12호
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• pp.343-351
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• 2020

본 연구는 노인을 대상으로 인지기능에 관한 교육과 함께 주의, 기억, 실행기능, 기억책략 등을 다루는 인지과제를 수행하는 인지훈련을 실시하여 훈련 이전의 인지기능 수준은 어떤 개인적 특성과 관련이 있는지, 주관적 인지감퇴는 실제적인 인지감퇴를 반영하는지, 인지훈련의 효과는 어떤 개인 특성과 관련이 있는지를 알아보기 위해 수행되었다. 연구 참가자는 건강한 노인 20명으로 14회기의 인지훈련을 주 1회, 회기당 2시간씩 진행하였으며 사전 및 사후로 검사를 실시하였다. 연구 결과, 인지기능은 연령과 자아존중감, 성격 특질 중 외향성과 개방성이 관련이 있는 것으로 나타났으며, 주관적인 인지감퇴는 객관적인 인지기능보다는 우울, 불안, 성격, 자기효능감, 자아존중감, 주관적 연령과의 상관이 유의하였다. 또한 인지훈련을 통해 전반적인 인지기능을 측정하는 정신상태, 기억, 전두엽기능 검사 점수가 향상되었으며 인지훈련의 효과는 연령, 주관적 인지감퇴, 불안, 자기효능감, 자아존중감, 주관적 연령, 성격과 관련이 있는 것으로 나타났다. 이러한 결과는 어떤 특성의 노인이 인지노화에 취약한지 알려주며, 인지훈련의 효과를 높이기 위해 교육 참가자의 특성을 고려해야 한다는 것을 시사한다.

• 동의생리병리학회지
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• 제22권3호
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• pp.556-561
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• 2008

ChongMyeong-Tang (CMT) have been used clinically to treat patient with amnesia and dementia. In addition, CMT have been also used for examinee to improve learning ability in Korea. This study was designed to investigate the effects of Gagam-ChongMeong-Tang (GCMT) on cognitive dysfunction recovery after ischemic brain injury in rats. Rats were divided into three groups; (1) normal, (2) commercial diet after ischemic brain injury (control), (3) CMT diet after ischemic brain injury (experiment). In our study, we carried out Morris water maze test for cognitive motor behavior test and immunohistochemistry study through the change BDNF in the hippocampus($7^{th},\;14^{th}\;day$). In Morris water maze test, cognitive motor function recovery was significantly increased in the experiment group as compared with control group on $7^{th}\;and\;14^{th}\;day$ day (p<0.01). In immunohistochemistric response of BDNF in the hippocampus, more immune reaction was investigated in the experiment group as compared with control group on $7^{th}\;and\;14^{th}\;day$. Especially more immune reaction was experimented $14^{th}$ day. These results imply that GCMT can play a role in facilitating recovery of cognitive function after ischemic brain injury in rats.

• 동의생리병리학회지
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• 제36권1호
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• pp.18-22
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• 2022

To investigate effects of cognitive function improvement whether against Taegeuk ginseng on scopolamine-induced memory impairment in rats. All experiments were conducted in three groups: the control group (CTR), the scopolamine 0.4mg/kg (SCP), and the scopolamine (SCP+T) treated with Taegeuk ginseng 100 mg/kg. Taegeuk ginseng 100 mg/kg daily was orally administered for one month and treated with scopolamine was only for 7 consecutive days on the Morris water maze task. 3 weeks after oral administration of Taegeuk ginseng, subjects were performed the Morris water maze test for 8 days and then the open-field exploration test which to assessed for cognitive function improvement. After behavioral testing, subjects were sacrificed and microdissected brains for neurochemical analysis. In the cognitive-behavioral test, long-term administration of Taegeuk ginseng improved spatial navigation learning task compared with the impeded by scopolamine treatment. In neurochemistry, the expression of the synaptic marker PSD95 (postsynaptic density protein 95) was increased in the hippocampus compared to the scopolamine group. Also, brain-derived neurotrophic factor (BDNF) expression was significantly increased in the taegeuk ginseng administration group. These data suggested that long-term administration of taegeuk ginseng might improve cognitive-behavioral functions on hippocampal related spatial learning memory, and it was correlated with neurotropic and synaptic reinforcement. In conclusion, treatment with taegeuk ginseng may positive outcome on learning and memory deficit disorders.

• 지역사회간호학회지
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• 제7권2호
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• pp.216-228
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• 1996

The purposes of this study were to investigate levels of physical, cognitive, and social functioning in institutionalized elderly. The subjects were 78 residents of a nursing home for the elderly in Pusan. The data were collected from June 24th to July 8th, 1996 using interview and observational method. The structured questionnaires developed by Kim, by Kwon & Park, and by researcher were adopted to measure physical, cognitive, and social function, respectively. The data were analyzed using percentages, means, t test, ANOVA, Pearson correlation coefficient, Cronbach's alpha with the SPSS PC programs. The results were summarized as follows: 1. 34.2% of the subjects had a paralysis, strokes 26.3%, hearing impairment 15.9%, vision impairment 11.8%, mental disturbance 11.8%, cognitive disturbance 10.5%. 2. The mean score on the physical function for the subjects was 73.14, and the items with low functioning levels were 'ascending the stairs', 'bathing' in that order. There was no significant difference in physical function according to the following demographic characteristics: sex, age, and education level. 3. 50.0% of subjects was categorized 'definite dementia', 'questionable dementia' 11.5%, 'definite non-dementia' 38.5%. There was a significant difference in cognitive function according to sex, but were no significant differences according to following demographic characteristics: age and education level. 4. The mean score on the social function for the subjects was 17.60. The items with comparatively high score were in simple activities such as 'enjoying talking with his friends', 'watching TV or listening to the radio', and the items with low score were in complex activities such as 'enjoying a hobby',. 'enjoying a game', 'reading the newspaper or book'. There were no significant differences in social function according to sex and age, but was a significant difference according to education level. 5. Social function was positively correlated with both physical function and cognitive function.

• 인간행동과 음악연구
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• 제13권1호
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• pp.1-18
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• 2016

본 연구는 아동의 리듬 수행 능력과 인지 능력 간 상관관계를 알아보고자 하였다. 이를 위해 평균 연령 9세의 초등학생 59명을 대상으로 iPad 기반 리듬 수행 검사, 숫자 외우기 검사(DST), 아동 색선로 검사(CCTT), 키보드를 활용한 자가탭핑 검사를 진행하였다. 검사 결과, 리듬 재산출의 정확도(accuracy)를 측정하는 리듬 수행 검사 1단계 10개 문항은 자가탭핑 평균속도(s)와 유의한 상관관계가 나타났으며, 리듬 수행 검사 2단계에서 측정하는 그룹핑(grouping) 능력은 CCTT 검사 결과와 유의한 상관관계가 있었다. 특히 문항 특성에 따른 결과를 분석한 결과 일정한 리듬이 두 번 이상 연속으로 반복되어 제공되는 리듬꼴의 정확한 수행은 자가탭핑 속도와 부적 상관관계가 있었으며, 분할박이 많은 리듬꼴의 리듬 수행력은 CCTT, 즉 집행기능과 유의한 상관관계가 있는 것으로 나타났다. 본 연구 결과 리듬 재산출 과제가 초등학교 학령기 아동의 인지 기능 검사 결과와 유의한 상관관계에 있다는 것을 확인하였다. 또한 아동이 산출하는 자가탭핑 속도, 즉 내적 리듬 특성이 인지 기능과 상관관계에 있음을 알 수 있었다. 본 연구는 학령기 아동의 리듬 수행력과 관련된 기초 자료를 제시하고, 이러한 리듬수행력이 인지 기능의 측정 지표가 될 수 있는 가능성이 있음을 시사한다. 본 연구에서 도출된 결과를 통해 추후 리듬꼴의 특징 및 리듬 과제의 난이도에 따른 리듬 수행력이 학령기 아동의 인지적, 정서행동적, 음악적 특성을 다각적으로 평가할 수 있는 가능성 또한 제언되었다.

• Journal of Korean Neurosurgical Society
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• 제30권7호
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• pp.842-848
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• 2001

Objectives : The mortality rate of subarachnoid hemorrhage(SAH) has been reduced recently due to refinement of microsurgical technique and improved perioperative management. Also, many survivors of SAH show excellent neurological recoveries. However, we found that a high proportion of the survivors do not fully regain their premorbid status in cognitive and memory function. Object of this study is to evaluate which factors might influence on cognitive and memory impairment in ruptured aneurysmal SAH patients. Methods : In this prospective study, a series of 66 patients with aneurysmal subarachnoid hemorrhage(SAH) from 1996 to 1998, most of whom had a "good" or "fair" neurological outcome, were assessed with various tests of cognition and memory function. All patients underwent clipping operation by pterional approach. Right side approach was performed in 16 case and left 21 cases. K-WAIS(Korean-Wechsler Adult Intelligence Scale) was used as method of cognition and memory function test. The time interval between SAH and assessment varied between 4 months and 8 months, averaging 6.2 months. Statistical analyses were carried out for each test score to see whether aneurysm site(A-com : non A-com), route of approach, age and sex, vasospasm, Hunt-Hess grade and Fisher CT group at admission, Glasgow Outcome Scale(GOS) at discharge affect cognitive and memory function. Results : Aneurysm site was not shown to be associated with performance on any test, and the initial grade (Hunt-Hess grade, Fisher CT group) of SAH and vasospasm had only minimal predictive values. The grade at discharge( GOS) was proved to be the best predictor of impairment of cognition and memory function within 1 year after operation. Conclusion : The authors conclude that the diffuse effects of SAH are more important than focal neuropathology in relation to cognitive impairment in this group of patients.

• 대한물리의학회지
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• 제13권4호
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• pp.59-65
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• 2018

PURPOSE: The purpose of the present study is to investigate the changes in the cognitive function of elderly dementia patients residing in a residential care facility, following six weeks of brain-computer interface (BCI)-based cognitive training and to determine whether BCI-based cognitive training effectively improves their cognitive functions. METHODS: Thirty subjects diagnosed with dementia were randomly assigned to either the experimental or control group. Pre- and post-test cognitive function assessments were conducted using the mini mental state examination-Korean (MMSE-K) and Korean-dementia rating scale (K-DRS). The experimental group received BCI-based cognitive training, which consisted of games such as flying a ball and exploding a bomb, while the control group participated in music listening activities and National Health Gymnastics. Both groups engaged in a total of 18 sessions (3 times per week for 6 weeks, for 40 minutes per session). RESULTS: After 6 weeks of intervention, the experimental group had significantly increased MMSE-K scores ($19.53{\pm}1.30$ to $22.20{\pm}1.15$; p<.0011) and total K-DRS scores ($87.20{\pm}4.16$ to $99.33{\pm}1.15$; p<.0011). In addition, the experimental group showed greater cognitive improvements than the control group. CONCLUSION: The results of this study suggest that BCI-based cognitive training is a positive intervention tool for improving the cognitive function of dementia patients.

• 지역사회간호학회지
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• 제30권4호
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• pp.508-517
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• 2019

Purpose: The aim of this study was to identify the participation rate of the National Health Screening Program (NHSP) and its influencing factors by cognitive function level in Korean older adults. Methods: This study was a secondary analysis using data from the survey of the Korean Longitudinal Study of Aging in 2016. The data were analyzed using 𝑥² test and multiple logistic regression. Results: The participation rates of the NHSP in the mild cognitive impairment group (79.6%) and the suspected dementia group (58.0%) were lower than the normal cognitive function group (88.1%). The factors influencing NHSP varied by cognitive function level. Especially, in the suspected dementia group, higher participation rates of the NHSP were associated with living in rural areas, enrollment in private health insurance, no depressive symptoms, participation in social activities, and no living with children. Depression and participation in social activities influenced participation in NHSP in all groups. Conclusion: This study suggests that interventions differentiated by cognitive function level are important for increasing the participation in the health screening.