• Korean Journal of Psychosomatic Medicine
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• v.24 no.2
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• pp.227-235
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• 2016

Objectives : The aims of this study were to know the frequency of cognitive dysfunction among patients with autoimmune thyroid disorders, and to reveal influencing factors on it, especially to clarify association with autoimmune thyroid antibodies. Methods : From sixty-five female patients with autoimmune thyroid disorders, demographic data were obtained by structured interview. Their cognitive funtions were measured using the MMSE-K and the MoCA-K tests. Depression was evaluated by the K-HDRS. Results : 1) Among patients with autoimmune thyroid disorders, 7.69% of them were below 24 on the MMSE-K, while 10.77% were below 22 on the MoCA-K. The frequency of cognitive deficit was not significantly different according to having positivity to antimicrosomal antibodies or not. 2) The antimicrosomal antibody-positive patients had significantly higher antithyroglobulin antibody titers, antimicrosomal antibody titers, and TSH concentration, while had significantly lower free T4 levels(p<0.05, respectively). 3) The total scores of the MMSE-K and the MoCA-K had significant correlation with age, marital status, antithyroglobulin antibody titers and K-HDRS(p<0.05, respectively). 4) The regression analysis revealed that variables such as age, education, autoimmune thyroid antibodies, thyroid function and depression did not influence on cognitive function of patients with autoimmune thyroid disorders. Conclusions : Our results could not support that cognitive function of patients with autoimmune thyroid disorders had correlation with autoimmune thyroid antibodies.

• Journal of Korean Academy of Nursing
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• v.46 no.1
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• pp.1-18
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• 2016

Purpose: This study was conducted to synthesis the results of research on relationships of cognitive impairment with multi-dimensional correlates of rheumatic disease through a systematic literature review and meta-analysis. Methods: For the study purpose, 23 studies were selected through a systematic process of searching the literature. Results: The study results showed that among general characteristics, age and education were the variables having a significant relationship with cognitive impairment. Among health risk factors, obesity appeared to have a significant positive relationship with cognitive impairment. For past history, diabetes and hypertension were shown to have a significant positive relationship with cognitive impairment. It was noted also that aPL, one of the physiological factor, had significant association with cognitive impairment. None of the medication related factors had a significant relationship with cognitive impairment. Results showed that among disease related factors, disease activity had the highest relationship with cognitive impairment. Depression, among psychological factors, was the only variable having a significant relationship with cognitive impairment. Conclusion: The findings indicate that the variables strongly impacting on cognitive impairment in rheumatic disease are depression and disease activity.

• Korean Journal of Biological Psychiatry
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• v.5 no.1
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• pp.71-82
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• 1998

The neuropsychiatric sequelae of traumatic brain injury are effects on complex aspect of cognition, emotion and behavior. They include problems with attention and arousal, concentration, executive function, intellectual changes, memory inpairments, personality changes, affective disorders, anxiety disorders, psychosis, apathy, aggression, and irritability. There are many useful therapeutic approaches available for people who have been brain injuries. Although a multifactioral, multidisciplinary, collaborative approach to treatment is proposed, for purposes of exposition the author have divided treatment into psychopharmacological, cognitive, behavioral, psychological, and social interventions.

• Journal of Korean Neurosurgical Society
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• v.66 no.3
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• pp.289-297
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• 2023

Technological advances in neonatology led to the improvement of the survival rate in preterm babies with very low birth weights. However, intraventricular hemorrhage (IVH) has been one of the major complications of prematurity. IVH is relevant to neurodevelopmental disorders, such as cerebral palsy, language and cognitive impairments, and neurosensory and psychiatric problems, especially when combined with brain parenchymal injuries. Additionally, severe IVH requiring shunt insertion is associated with a higher risk of adverse neurodevelopmental outcomes. Multidisciplinary and longitudinal rehabilitation should be provided for these children based on the patients' life cycles. During the infantile period, it is essential to detect high-risk infants based on neuromotor examinations and provide early intervention as soon as possible. As babies grow up, close monitoring of language and cognitive development is needed. Moreover, providing continuous rehabilitation with task-specific and intensive repetitive training could improve functional outcomes in children with mild-to-moderate disabilities. After school age, maintaining the level of physical activity and managing complications are also needed.

• BMB Reports
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• v.49 no.9
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• pp.474-487
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• 2016

Itch is one of the most distressing sensations that substantially impair quality of life. It is a cardinal symptom of many skin diseases and is also caused by a variety of systemic disorders. Unfortunately, currently available itch medications are ineffective in many chronic itch conditions, and they often cause undesirable side effects. To develop novel therapeutic strategies, it is essential to identify primary afferent neurons that selectively respond to itch mediators as well as the central nervous system components that process the sensation of itch and initiate behavioral responses. This review summarizes recent progress in the study of itch, focusing on itch-selective receptors, signaling molecules, neuronal pathways from the primary sensory neurons to the brain, and potential decoding mechanisms based on which itch is distinguished from pain.

• Anxiety and mood
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• v.12 no.2
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• pp.79-85
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• 2016

Sexually abused victims suffer not only physical damage, but they may also experience an array of additional problems ranging from acute fear, depressed mood, anxiety, shame, or insomnia to long-term psychiatric disorders. Trauma Focused Cognitive Behavioral Therapy (TF-CBT) is known to have excellent therapeutic effects for trauma victims including victims of sexual violence. CBT treatment includes stress immunity training, relaxation training, and acceptance and commitment therapy. In foreign countries TF-CBT is carried out online in order to increase the therapeutic accessibility for the victim and improve the quality of the interview for the therapists. As a result, those victims who have difficulties in requesting external help, who live in remote areas, or who have limited time may now have access to the service and benefit from the online education programs. A website providing an online based TF-CBT program was initiated in Korea also. Through the website, victims and their guardians may obtain therapeutic information without the need for face-to-face meetings with therapists. Our goal is to create a system with this website which will provide therapeutic assistance to sexual violence victims and improve the quality of the counseling provided by the therapist.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.8
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• pp.747-752
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• 2020

This study examines cognitive impairment, which is one of the results from social exclusion and leads to logical reasoning disorders. This study also investigate how cognitive errors called abductive inference error occur due to cognitive impairment. Present study was performed with 81 college students. Participants were randomly assigned to the group who has experienced social exclusion or to the group who has not experience the social exclusion. We analyzed how the degree of error of abductive inference differs according to the social exclusion experience. The group who has experienced social exclusion showed a higher level of abductive inference error than the group who has not experience. The abductive condition inference value of the group who has experienced social exclusion was higher in the group with the deduction condition inference value of 90% than in the group with the deduction condition inference value of 10%, and the difference was also significant. This study extended the concepts of cognitive impairments, escape theory, cognitive narrowing which are used to explain addiction behavior to human cognitive bias. Also this study confirmed that social exclusion experience increased cognitive impairment and abductive inference error. Future research directions and implications were discussed and suggested.

• Korean Journal of Radiology
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• v.25 no.2
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• pp.214-215
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• 2024

• Dementia and Neurocognitive Disorders
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• v.22 no.1
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• pp.43-45
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• 2023

• Dementia and Neurocognitive Disorders
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• v.23 no.1
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• pp.67-70
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• 2024