• 대한통합의학회지
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• 제11권2호
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• pp.77-86
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• 2023

Purpose : This study systematically assessed 9 emotion-function programs for schizophrenic individuals that have been implemented over the past 10 years in Korea and abroad, with the objective of providing clinical grounds and data for further programs. Methods : This study identified 2,558 studies from among those registered in the RISS, KISS, EMbase, PubMed and Scopus databases from 2013 to September 2023, using 'schizophrenia' AND 'emotion' AND ('program' OR 'therapy') as keywords. Of the 2,558 studies retrieved from electronic databases, 602 duplicate papers were excluded. After this process, 1,915 papers that did not meet the study's inclusion and exclusion criteria were excluded based on their titles and abstracts. Following a review of the texts of the remaining 41 papers, nine papers were finally selected, excluding 32 papers according to the selection and exclusion criteria. Results : Programs for the emotional function of patients with schizophrenia have continued to be researched. The results of an evaluation on the quality of the selected literature confirmed that a majority of the reviewed items were "uncertain", confirming that there was a risk of bias. The interventions for emotions included art, cognitive-behavioral, and physical programs, of which art programs were frequently applied. Most of the interventions were implemented in hospitals. The dependent variables for evaluating emotions included emotional expression, depression, anxiety, and positive emotions, and among them, emotional expression was used most frequently. Accordingly, the Berkeley expressivity questionnaire was commonly used as an evaluation tool. Conclusion : This study is significant for intending to analyze domestic and overseas programs for the emotions of patients with schizophrenia, thereby proposing the direction for planning and applying interventions in clinical settings. In follow-up studies, it will be necessary to develop a protocol that confirms interventions according to the settings and patient characteristics of programs and expands the scope of literature reviews.

• 인간행동과 음악연구
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• 제19권2호
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• pp.1-26
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• 2022

본 연구는 중등도 및 중증 치매 노인을 대상으로 한 국내·외 음악 중재 연구를 고찰하여 연구 동향을 알아보고, 참여자의 임상적 특성이 고려된 음악 중재의 특징을 알아보고자 시행되었다. 검색을 통해 선정된 17편의 문헌을 분석한 결과, 종속 변인은 행동심리증상 등 심리·정서적 변인이 주를 이루는 것으로 나타났다. 중재 참여유형을 살펴보면 내담자의 활동 참여가 요구되는 적극적 유형이 감상만 하는 수용적 유형보다 많았다. 중재의 일반적 특성으로는 과반수가 라이브 음악, 친숙하고 선호하는 음악 선곡, 리듬기반 연주활동을 제공한 것으로 나타났다. 적극적 유형의 음악중재 내용을 살펴보면 음악에 맞춰 그룹 연주나 노래를 하며 유발되는 감정을 말하도록 하는 것으로 참여자가 중등도와 중증이 혼합된 경우와 중증 치매만인 경우 차이점이 없어 중증 치매가 지닌 기능적 한계가 충분히 반영되지 않은 것으로 나타났다. 추후 연구에서는 중증 치매 노인의 의미있는 음악경험을 위한 중재구성과 내담자의 치매 진행 정도에 따른 음악치료 전략 개발이 필요하다.

• 대한불안의학회지
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• 제2권1호
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• pp.50-55
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• 2006

Objectives : In the psychiatry, structured interview is very important tool to be used in epidemiological or psychopharmacological studies. However, investigators often find that the administration of comprehensive diagnostic interviews is time-consuming and expensive to be used in clinical or research settings. Considering these points, Sheehan and his colleagues developed MINI (Mini International Neuropsychiatric Interview) to meet the need for a brief, reliable, and valid structured diagnostic interview for psychiatric disorders. The MINI has been translated into many languages and used in many countries. Therefore, we translated the MINI into Korean and determined its validity in this study. Methods : Twohundred seventy patients and normal subjects participated in the validation of the MINI versus an expert's professional opinion. Schizophrenia and other psychotic disorders, mood disorders including major depressive disorder and bipolar disorder, anxiety disorders including panic and other phobic disorders, and alcohol dependence were included in this study. The validity was obtained by examination whether MINI based diagnoses were compatible with diagnoses by expert psychiatrists. Results : The range of Kappa values was 0.22 (somatoform disorder) to 0.93 (bipolar disorder - past). Overall agreement between MINI and expert's diagnoses were good. The Kappa values for anxiety disorders seemed to be higher than those for other disorders. Conclusion : The MINI Korean version has the good validity. It also has potential applications as a diagnostic tool for psychiatric disorders.

• 생물정신의학
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• 제14권1호
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• pp.5-13
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• 2007

Objectives : Depression disturbs the individual life from the loss of productivity to suicide. Furthermore the whole society is also influenced by depression in social and economic areas. Many scientific treatment methods are known to be effective in depression. But in reality more than half of patients with depression prefer self help treatment rather than medically based treatment. For the patients with mild depression and primary physicians, it is reasonable to provide the evidence based self care including self help or alternative treatment. This study is supported by the Korean Health 21 R&D Project for the Depression Center to establish the Korean treatment guideline for depression. Methods : The members of Depression Center including the authors attended the workshops where the methods of evidence based medicine such as literature search, quality evaluation of the articles, making the level of evidence were educated. The professional librarians helped the authors for get the searched articles. Among the total of 354 abstracts of systemic review and 300 abstracts of random controlled trials, 3 systemic reviews and 2 random controlled trials were the main structure of evaluation. Result : Among the 37 self care methods known to be effective for depression, 11 kinds of methods were worth of evaluation. The first step for the self care of mild depression is to use St. John's wort, exercise, bibliotherapy, and light therapy in depression during winter season. Acupuncture, negative ion therapy, massage, relaxation technique are known to be efective with evidence. Music therapy, hypnotherapy, and aromatherapy are known to be effective but until now the evidences is insufficient and further evaluations are needed. Conclusion : Among 11 listed self-care methods, several methods need more evidence especially in Korean situation. Exercise is the most recommendable evidence based self care method in Korea nowadays. St. John's wort is effective with evidence, but it is not the OTC drug in Korea, so it is not recommendable now. For the bibliotherapy, there is no book such as "Feeling Good" in Korea. Only the introductory book about depression is available. Publishing the self help book based upon cognitive behavioral approach or psychodynamic approach is needed. Light therapy is practiced in a few clinics, but not self-help style. Exposure to the sunlight is recommended in the level of commen sense. These self care methods are for the mild patient. Moderate to severe patients with depression should seek the professional treatment.

• 대한지역사회영양학회지
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• 제15권1호
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• pp.73-82
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• 2010

This study was conducted to investigate the effects of a weight control programs on BMI, nutrition knowledge, physical fitness and stress level of adult obese women. The subjects of this study were 36 adult obese women aged 30-65 years whose BMI were above $23\;kg/m^2$. The weight control program for obese women included nutritional education, exercise and cognitive behavioral therapy for 12 weeks. The BMI of the subjects was significantly decreased (p < 0.001) from $27.1\;kg/m^2$ to $26.4\;kg/m^2$ after the 12 weeks of the weight control program. In addition, the weight of body fat was significantly decreased (p < 0.001) and % body fat was significantly decreased (p < 0.05) from 35.4% to 34.9% after completion of the weight control program. In addition, nutritional knowledge (p < 0.001) and eating behavior scores (p < 0.01) were significantly increased. However, the food intake scores were not changed after the program. Stress levels of the adult obese women were significantly decreased (p < 0.001) from 85.63 to 66.88 and also obesity stress levels were significantly decreased (p < 0.01) after the weight control program. In the physical fitness levels of the subjects, muscle endurance (p < 0.05) and ability of balance (p < 0.01) were significantly improved after completion of the weight control program. There were positive significant correlations between general stress and obesity stress level (p < 0.05), and negative correlations between stress level and food intake score (p < 0.05). These results showed that the weight control program for adult obese women may be effectively used to improve weight reduction, physical fitness and stress levels.

• 동의신경정신과학회지
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• 제28권1호
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• pp.1-13
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• 2017

Objectives: The purpose of this study is to investigate the trends in acupuncture research on Internet addiction disorder. Methods: Clinical research papers on acupuncture treatment were searched and selected. Seven databases, including English, Chinese, Japanese, and Korean databases, were searched systematically. Non-clinical, non-acupuncture, and unpublished studies were excluded. The characteristics of the included articles were described, and these articles were assessed by the Risk of Bias (RoB) tool or the Risk of Bias Assessment for Non-randomized Studies (RoBANS) tool. Results: Ten clinical studies on Internet addiction disorder were finally selected, and all of these studies were published in China. The electroacupuncture (EA) method was used in most of the acupuncture treatment studies. Most of the psychotherapy studies used cognitive behavioral therapy (CBT) in the control group. Most of the studies showed effective results. The results of this study suggest that the combination of acupuncture and psychotherapy is more effective than either treatment modality alone. However, the quality of these clinical studies was low. Conclusions: According to this study, acupuncture treatment seems to have excellent effects in Internet addiction disorder. However, the quality of most studies was low. Therefore, higher quality research on Internet addiction disorder is required.

• The Korean Journal of Pain
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• 제14권1호
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• pp.110-113
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• 2001

In controlling chronic intractable pains, the current therapeutic methods used are exercise, over the counter medication, cognitive-behavioral therapy, opioid medication, neural blockade, operation, etc., spinal cord stimulation being the last resort. Spinal cord stimulation was initiated when Shearly and others clinically tested the Gate control theory of Melzack and Wall. This had triggered the advancement of theoretic research on the mechanism and hardware necessary and has resulted in an accumulation of clinical experiences. This is known to be effective for treating sympathetic pain, arachnoiditis, failed back pain syndrome, radiculopathy, peripheral vascular disease, phantom limb syndrome, post-herpetic neuralgia, peripheral neuropathy, and angina pectoris. This report describes our experience in experimental spinal cord stimulation in patients with simultaneous post-herpetic neuralgia and herniated intervertebral disc. There wasn't any improvement in the post-herpetic neuralgia but the symptoms of a herniated intervertebral disc was much ameliorated. This was quite an unexpected result. The patient's back pain returned when the stimulation stopped.

• 한국동물번식학회:학술대회논문집
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• 한국동물번식학회 2003년도 학술발표대회 발표논문초록집
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• pp.80-80
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• 2003

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor, cognitive, and psychiatric symptoms, accompanied by marked cell death in the striatum and cortex. Stereotaxic injection of quinolinic acid (QA) into striatum results in a degeneration of GABAergic neurons and exhibits abnormal motor behaviors typical of the illness. The objective of this study was carried out to obtain basic information about whether parthenogenetic mouse embryonic stem (PmES) cells are suitable for cell replacement therapy of HD. To establish PmES cell lines, hybrid F1 (C57BL/6xCBA/N) mouse oocytes were treated with 7% ethanol for 5 min and cytochalasin-B for 4 hr to initiate spontaneous cleavage. Thus established PmES cells were induced to differentiate using bFGF (20ng/ml) followed by selection of neuronal precursor cells for 8 days in N2 medium. After selection, cells were expanded at the presence of bFGF (20 ng/ml) for another 6 days, then a final differentiation step in N2 medium for 7 days. To establish recipient animal models of HD, young adult mice (7 weeks age ICR mice) were lesioned unilaterally with a stereotaxic injection of QA (60 nM) into the striatum and the rotational behavior of the animals was tested using apomorphine (0.1mg/kg, IP) 7 days after the induction of lesion. Animals rotating more than 120 turns per hour were selected and the differentiated PmES cells (1$\times$10$^4$cells/ul) were implanted into striatum. Four weeks after the graft, immunohistochemical studies revealed the presence of cells reactive to anti-NeuN antibody. However, only a slight improvement of motor behavior was observed. By Nissl staining, cell mass resembling tumor was found at the graft site and near cortex which may explain the slight behavioral improvement. Detailed experiment on cell viability, differentiation and migration explanted in vivo is currently being studied.

• 한국콘텐츠학회논문지
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• 제14권6호
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• pp.219-228
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• 2014

목적 본 연구는 간질 아동에게 제공된 심리사회적 중재들의 효과에 대한 연구동향을 밝혀 추후 간질아동을 위한 간호중재의 기초자료로 활용하기 위함이다. 방법 PRISMA 문헌선택 흐름도에 따라 데이터베이스(Ovid-MEDLINE, EMBASE, PubMed, CINAHL, The Cochrane library, KMbase, and Koreamed)를 통해 454개의 논문들이 검색되었고 선정 및 제외기준에 의해 7개의 논문이 최종적으로 선택되었다. 2명의 연구자가 분석에 포함된 모든 연구를 독립적으로 검토하였고, 방법론적인 질 평가를 위해 코크란의 Risk of Bias 도구와 국내의 Risk of Bias Assessment tool for Non-randomized Study 도구를 이용하였다. 결과 중재 전략의 형태는 4가지로 분류되었다: 교육; 상담; 인지행동치료; 신체활동. 중재의 목표들은 매우 다양하였다. 결론 각각의 중재들은 간질관련 건강 결과에 부분적으로 긍정적인 효과를 보여주었지만 불충분한 중재 정보, 타당도가 떨어지는 결과 측정법, 적은 표본 수, 연구 설계의 제한점과 같은 방법론적인 약점들이 있었다.

• 한국콘텐츠학회논문지
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• 제14권3호
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• pp.269-276
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• 2014

본 연구에서는 라쉬분석을 통하여 한글판 학교기능평가(School Function Assessment)도구의 구성타당도, 척도 적합성을 검증함으로써 이 평가도구의 국내 사용을 위한 기초자료를 제시하고자 한다. 서울 및 경기, 충청 지역의 만 7세~12세(초등학교 1학년~6학년)인 98명 장애아동을 대상으로 아동의 보호자 및 담임 특수교사 또는 작업치료사와 직접 면담 또는 전화를 통하여 자료를 수집하였다. 자료분석은 라쉬분석을 통하여 단일차원모형(unidimensionality)에 대한 적합통계치(fit statistics)를 제시하였다. 또한, 라쉬분석의 평정척도모형(rating scale model)을 이용하여 평정척도의 적합성 분석을 실시하였다. 라쉬분석 결과 각 25개 하위척도 내 총 328개 항목 중 단일모형 적합통계치가 부적합한 항목은 Part II 과제지원 영역에서 총 4개였고, Part III 신체적 과제 영역에서 부적합 항목은 18개, 인지/행동적 과제 영역에서 부적합 항목은 14개 항목으로 나타났다. 한글판 학교기능평가 도구의 모든 평가 하위영역의 5점 평정척도는 적합한 것으로 나타났다 본 연구를 통하여 한글판 학교기능평가 도구의 구성타당도와 평정척도 적합성을 확인하였다. 그 결과 5점 평정척도는 적합한 것으로 나타났으나, 일부 부적합 항목이 발견되어 앞으로 국내 타당도 확립과 준거제시를 위한 연구가 추후 이루어져야 할 것으로 판단된다.