• Nuclear Engineering and Technology
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• v.39 no.6
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• pp.703-716
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• 2007

As digital and computer technologies have grown, human-machine interfaces (HMIs) have evolved. In safety-critical systems, especially in nuclear power plants (NPPs), HMIs are important for reducing operational costs, the number of necessary operators, and the probability of accident occurrence. Efforts have been made to improve main control room (MCR) interface design and to develop automated or decision support systems to ensure convenient operation and maintenance. In this paper, an integrated decision support system to aid operator cognitive processes is proposed for advanced MCRs of future NPPs. This work suggests the design concept of a decision support system which accounts for an operator's cognitive processes. The proposed system supports not only a particular task, but also the entire operation process based on a human cognitive process model. In this paper, the operator's operation processes are analyzed according to a human cognitive process model and appropriate support systems that support each cognitive process activity are suggested.

• Journal of The Korean Society of Integrative Medicine
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• v.5 no.4
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• pp.83-89
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• 2017

Purpose : This study aimed to investigate a study on the intervention of computerized cognitive rehabilitation applied to patients with dementia in Korea. Thus, a systematic discussion was conducted. Methods : Studies from January 2000 to December 2016 were searched in the Korea Education and Research Information Service. The main key words used were: "dementia," "computerized cognitive rehabilitation," "computerized cognitive training," "computer assisted cognitive therapy," and "computerized cognitive therapy." Result : A total of five studies were selected. The effects of the computerized cognitive rehabilitation therapy applied to patients with dementia resulted in improved cognitive functions, as well as daily living and activities instrumental to daily living. There was also an increase in brain activity. The qualitative aspects of this study showed a low level of internal and external validities due to the small number of subjects, short period of intervention, and limited study environment. Conclusion : In the future, it is necessary to continue a study in which the level of evidence is high to determine whether various cognitive rehabilitation programs are effectively applied to patients with dementia.

• Journal of Community Nutrition
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• v.5 no.3
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• pp.173-177
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• 2003

This study was done to investigate the relationship of socioeconomic status and food intake to cognitive status of the older population. The subjects of this study consisted of 214 older persons aged 60 - 84 years. Interviews were conducted using the health-related habits and food frequency questionnaires to provide basic information for nutrition education program. We evaluated the current food consumption-pattern and cognitive status of the subjects. The results of this study were as follows： Mean age of the subjects was 69.7${\pm}$7.4 years. The average cognitive function score of the subjects was 7.9${\pm}$2.0 (full score was 10.0). Male had a higher cognitive status score than female. There was significant difference between cognitive status score and age, education level, pocket money, physical activity and family type. The subjects who had a higher cognitive status score ate more fish and meats group and milk and milk products than the subjects that had a lower cognitive status score. These results have demonstrated that various socioeconomic variables and food intake pattern affect on cognitive status with aging and suggest that proper nutrition education and adequate nutrient intake in quality and quantity are essential in maintaining cognitive status in later life.

• Journal of Digital Convergence
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• v.15 no.4
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• pp.511-519
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• 2017

This study developed a occupational therapy convergent activity program to provide dementia patients admitted to the daytime ward, and investigated the program's effect on the hand and cognitive functions and instrumental activities of daily living. A total of 34 dementia patients were divided into two groups: a convergent occupational therapy program and medication were provided for 17 patients, and medication alone was provided for a control group of 17. The intervention was performed for 24 weeks, 8 times per week, 192 times in total. A handgrip strength test was performed to examine hand function before and after the intervention, and the MMSE-K and GDS were performed to evaluate cognitive function. In addition, the K-IADL was used to assess instrumental activities of daily living. With intervention, the experimental group showed significant improvements in hand and cognitive function and instrumental activities of daily living. In contrast, the control group did not show improvements in hand and cognitive function or instrumental activities of daily living. In conclusion, the study showed that a convergent/integrated activity program for occupational therapy has a positive effect on hand and cognitive function as well as instrumental activities of daily living.

• Molecules and Cells
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• v.38 no.6
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• pp.535-539
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• 2015

Olfactory stimulation activates multiple signaling cascades in order to mediate activity-driven changes in gene expression that promote neuronal survival. To date, the mechanisms involved in activity-dependent olfactory neuronal survival have yet to be fully elucidated. In the current study, we observed that olfactory sensory stimulation, which caused neuronal activation, promoted activation of the phosphatidylinositol 3'-kinase (PI3K)/Akt pathway and the expression of Bcl-2, which were responsible for olfactory receptor neuron (ORN) survival. We demonstrated that Bcl-2 expression increased after odorant stimulation both in vivo and in vitro. We also showed that odorant stimulation activated Akt, and that Akt activation was completely blocked by incubation with both a PI3K inhibitor (LY294002) and Akt1 small interfering RNA. Moreover, blocking the PI3K/Akt pathway diminished the odorantinduced Bcl-2 expression, as well as the effects on odorant-induced ORN survival. A temporal difference was noted between the activation of Akt1 and the expression of Bcl-2 following odorant stimulation. Blocking the PI3K/Akt pathway did not affect ORN survival in the time range prior to the increase in Bcl-2 expression, implying that these two events, activation of the PI3K pathway and Bcl-2 induction, were tightly connected to promote post-translational ORN survival. Collectively, our results indicated that olfactory activity activated PI3K/Akt, induced Bcl-2, and promoted long term ORN survival as a result.

• Journal of Acupuncture Research
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• v.35 no.1
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• pp.28-36
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• 2018

Background: This study investigated the effects of acupuncture at Sobu (HT8) and Haenggan (LR2) on scopolamine-induced, cognitively impaired rats. Methods: Scopolamine-treated Sprague-Dawley rats were divided into 6 groups; normal, control, HT8, LR2, HT8 + LR2 and sham group. Cognitive impairment was induced by scopolamine, in control, and then in HT8, LR2, HT8 + LR2 and sham groups. Acupuncture treatment was performed at HT8, LR2, HT8 + LR2, and a random acupoint, respectively, every other day for 2 weeks. After each treatment, behavior change was observed and the rats were sacrificed. The change in brain-derived neurotrophic factor, glutathione peroxidase, and superoxide dismutase activity was evaluated by polymerase chain reaction. Results: Latency time to target in Morris Water-Maze test for the HT8 + LR2 group showed a significant decrease compared with control (p<0.05). Target crossing times and time zone ratios in Morris Water-Maze test for HT8 + LR2 group showed a significant increase compared with control (p<0.01). In the Y-Maze test the HT8 + LR2 group showed a significant increase compared with control (p<0.05). Brain-derived neurotrophic factor, glutathione peroxidase, and superoxide dismutase, in the HT8 + LR2 group, showed a significantly increased level compared with control (p<0.05). Neural activity of acetylcholine esterase in HT8 + LR2 group showed a significant decrease compared with the control group (p<0.01), choline acetyltransferase activity in the HT8 + LR2 group showed a significant increase compared with control (p<0.05). Conclusion: Acupuncture at HT8 + LR2 restored scopolamine-induced cognitive impairment, suggesting acupuncture could be an alternative to improve cognitive function.

• Journal of East-West Nursing Research
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• v.26 no.1
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• pp.39-51
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• 2020

Purpose: The purpose of this study was to develop family support oriented physical activity program for the male elderly with sarcopenia based on social cognitive theory. Methods: This program was developed through an analysis of 18 related intervention literatures, results of a focus group interview with 5 elderly men with sarcopenia and the content validity index of the program content adequacy and applicability by 6 experts. The combined exercise with resistance exercise and aerobic exercise was constructed in accordance with the recommendations of the American College of Sports Medicine (ACSM) and experts' opinions. Results: The program consists group education sessions (5 times, 60 minutes for each) for 12 weeks and family support oriented physical activity program composed of individual intervention (sending alarm for physical activity for 10 times and telephone monitoring for 2 times). The program also reflects the concept of self-efficacy and self-regulation, which are important factors for continuing physical activity through family support. The progressive resistance exercise was developed by composing 5-6 systemic movement forms that repeat 2-3 days a week and 2-5 sets at least. Conclusion: It is proposed to standardize the family support oriented physical activity program through the further studies so that the program can be utilized for the various groups of people who need increased level of physical activities.

• The Journal of the Korea Contents Association
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• v.21 no.2
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• pp.686-698
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• 2021

This study was conducted to analyze the mediating effect of health status and the moderating effect of economic activity in the relationship between depression and cognitive function of the elderly. For this, the data of 2017 National survey of Older Koreans that was collected all over country by Korea Institute for Health and Social Affairs were analyzed using Structural Equation Model for statistical analysis method. The results are as follows. First, the elderly's depression was found to have a negative effect on cognitive function and health status. Second, the health status of the elderly was found to have a positive effect on cognitive function. Third, a significant mediating effect of health status was founded in the relationship between depression and cognitive function. Fourth, the moderating effect of the elderly's economic activity was found in the path through which depression affects health status and health status affects cognitive function. Based on these research results, implications of social welfare were suggested.

• 한국경영정보학회:학술대회논문집
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• 2007.11a
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• pp.123-128
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• 2007

It has been argued that Enterprise systems (ES) implementations are overshadowed by a high failure rate despite their promised benefits. One of the commonly cited reasons for ES implementation failures in the context of mandatory use is end-user's unwillingness or sabotage to adopt or use systems. Considering that the appropriate management of expectations may play an important role in making positive behavior toward newly implemented systems, this study examines the effect of outcome expectations on the system use activity in the mandatory use context of information systems from the Social Cognitive Theory perspective. Structural equation model analysis using LISREL 8.7 provides significant support for the proposed relationships. The empirical results suggest that outcome expectations and user satisfaction have positive effects on system use activity conceptualized by immersion, reinvention, and learning. Theoretical and practical implications of the study shed some light on how to improve system use activity in the mandatory use context of information systems.

• Research in Community and Public Health Nursing
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• v.11 no.1
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• pp.80-89
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• 2000

This study was designed to investigate effects on cognitive perception. health promotion activity and life satisfaction of elderly. The participants for this study were 292 in senior citizen's center in S-city. The participants were categorized by two groups. one have taken exercise regularly. at least more than one a week for 6 months, the other have not. The measurement tools were the Perceived Benefit Scale developed by Walker, et al. and translated by Kim. Hee Ja(1994), the Life Satisfaction Index developed by Neugarten. etc. and translated by Lee. Ga Ok(1994) and Self efficacy Scale developed by Kim. Hee Ja (1994). The data were collected by personal interviews. which were taken from January 11 to 16. 1999, and analyzed by SAS 6.12. The major results of this study were as follows 1) Scores of self-efficacy were higher regular exercise group than irregular group. 2) Regular exercise group have taken exercise such as jogging, climbing and the other hands irregular group have not. 3) When the participants were categorized by smoking, other health promotion behavior (weight control. diet), both scores of life satisfaction index were higher smoking group than non-smoking group, other health promotion behavior than non-health promotion behavior. 4) There was no significant difference between the two groups in terms of perceived benefit, life satisfaction, From these findings, regular exercise program will be able to provide elderly with opportunity to change positively their lives in cognitive perception. health promotion activity.