• The Journal of Korean Institute of Communications and Information Sciences
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• v.41 no.1
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• pp.1-11
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• 2016

We investigate compressive sensing techniques to estimate sparse channel in Orthogonal Frequency Division Multiplexing(OFDM) systems. In the case of large channel delay spread, compressive sensing may not be applicable because it is affected by length of measurement vectors. In this paper, we increase length of measurement vector adding pilot information to OFDM data block. The increased measurement vector improves probability of finding path delay set and Mean Squared Error(MSE) performance. Simulation results show that signal recovery performance of a proposed scheme is better than conventional schemes.

• Archives of Pharmacal Research
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• v.22 no.2
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• pp.151-156
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• 1999

Despite the impressive antitumor activity of cisplatin, two major limitations of the drug, that is severe side effects and drug-resistance of cancer cells, make its use difficult of r cancer therapy. These limitations have resulted in a greate deal of effort having been expended into structural modifications of cisplatin. In this study, we tested two novel cisplatin analogues, (CPA)2 Pt[DOLYM] (COMP-I) and (DACH)Pt[DOLYM] (CoMP-II), for the mode of cytotoxic action against human tumor cells comparing with cisplatin and carboplatin in vitro. These two novel analogues had considerable cytotoxic activities against five kinds of human solid tumor cells, and especially COMP-II was more effective on HCT15 colon cancer cells than other compounds. In addition, COMP-II had cytostatic activity at low concentrations (10~0.3${\mu}g/ml$), but other compounds revealed little effect on tumor growth at the low concentration.

• Nuclear Engineering and Technology
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• v.53 no.11
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• pp.3543-3562
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• 2021

The methods and performance of a 3D pin-by-pin neutronics code based on the 2D/1D decoupling method are presented. The code was newly developed as an effort to achieve enhanced accuracy and high calculation performance that are sufficient for the use in practical nuclear design analyses. From the 3D diffusion-based finite difference method (FDM) formulation, decoupled planar formulations are established by treating pre-determined axial leakage as a source term. The decoupled axial problems are formulated with the radial leakage source term. To accelerate the pin-by-pin calculation, the two-level coarse mesh finite difference (CMFD) formulation, which consists of the multigroup node-wise CMFD and the two-group assembly-wise CMFD is implemented. To enhance the accuracy, both the discontinuity factor method and the super-homogenization (SPH) factor method are examined for pin-wise cross-section homogenization. The parallelization is achieved with the OpenMP package. The accuracy and performance of the pin-by-pin calculations are assessed with the VERA and APR1400 benchmark problems. It is demonstrated that pin-by-pin 2D/1D alternating calculations within the two-level 3D CMFD framework yield accurate solutions in about 30 s for the typical commercial core problems, on a parallel platform employing 32 threads.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.15 no.6
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• pp.225-228
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• 2005

We have grown the long persistent $SrAl_2O_4:Eu^{2+},\;Dy^{3+}$ phosphor single crystal by Verneuil method. The obtained single crystals were long persistent phosphorescence peaking at ${\lambda}=520nm$ with a size of about 5 mm diameter, 55 mm length. The melting temperature of $SrAl_2O_4:Eu^{2+},\;Dy^{3+}$ measured $T_{mp}=1968^{\circ}C$. The optimum composition was $SrCO_3:Al(OH)_3:Eu_2O_3:Dy_2O_3$ = 1 : 2 : 0.015 : 0.02. Flow rate of $H_2:O_2$ is about 4 : 1. Growthing rate is about 5 mm/hr. The spectra of the phosphorescence from the crystals are quite similar to those obtained with sintered powders used for luminous pigments. The crystalline structure of long persistent $SrAl_2O_4:Eu^{2+},\;Dy^{3+}$ phosphor single crystal was determined by X-ray diffraction.

• The Journal of Internal Korean Medicine
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• v.11 no.2
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• pp.1-15
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• 1990

Certain oriental medication have been shown to be effective in decreasing pulmonary vascular resistance and increasing cardiac output in primary pulmonary artery pressure secondary to pulmonary edema. So oleic acid was administered in 14 dogs in order to induce acute lung injury. And we studied the hemodynamics and blood gas changes of Pyengpaetang(50mg, 100mg) with continuous postive pressure was ventilation in pulmonary edema. The pulmonary edema group, arterial oxygenation was improved after 5 and $10cmH_2O$ PEEP(positive end expiratory pressure), but cardiovascular system was depressed. Blood pressure and cardiac output were decreased, and CVP, MP AP, PCWP were increased. In Pyengpaetang(50mg) group, mean aortic pressure was decreased and PCWP(pulmonary capillary wedge pressure) was decreased remarkably, while there was a significant increase in cardiac output. And there was improvement in $PaO_2$ and $PaCO_2$ without hemodynamic changes after applying 5cm $H_2O$ PEEP, but arterial blood gases$(PaO_2,\;PaCO_2)$ were improved, while cardiovascular effects were depressed after cm $H_2O$ PEEP. In Pyengpaetang(100mg) treated group, there was no significant hemodynamic change. But mean pulmonary arterial pressure was significantly increased, and cardiac output was decreased significantly after applying the more degree of PEEP. And blood gases were not changed significantly after applying the more degree of PEEP. The above results suggest that the effects of Pyengpaetang(50mg) group is superior to those of Pyengpaetang(100mg) group on the effects of hemodynamics and gas exchanges in acute lung injury in dogs. So we can conclude that lower degree PEEP 5cm $H_2O$ is more beneficial in Pyengpaetang(50mg) treated group.

• Journal of Microbiology and Biotechnology
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• v.24 no.6
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• pp.862-868
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• 2014

Certain Escherichia coli (E. coli) strains have the ability to cause diarrheal disease. Five types of diarrheagenic E. coli have been identified, including EHEC, ETEC, EPEC, EAEC, and EIEC. To detect these five diarrheagenic types rapidly, we developed a one-step multiplex PCR (MP-PCR) assay using nine primer pairs to amplify nine virulence genes specific to the different virotypes, with each group being represented (i.e., stx1 and stx2 for EHEC, lt, sth, and stp for ETEC, eaeA and bfpA for EPEC, aggR for EAEC, and ipaH for EIEC). The PCR primers were constructed using MultAlin. The sensitivity and specificity of the constructed multiplex PCR primers were measured using DNA isolated from diarrheagenic E. coli strains representing each group. The limits of detection were as follows: $5{\times}10^1CFU/ml$ for EHEC, $5{\times}10^3CFU/ml$ for ETEC expressing lt and sth, $5{\times}10^4CFU/ml$ for ETEC expressing stp, $5{\times}10^2CFU/ml$ for EPEC, $5{\times}10^4CFU/ml$ for EAEC, and $5{\times}10^2CFU/ml$ for EIEC. To confirm the specificity, C. jejuni, C. perfringens, S. Typhimurium, V. parahaemolyticus, L. monocytogenes, Y. enterocolitica, B. cereus, and S. aureus were used as negative controls, and no amplification was obtained for these. Moreover, this kit was validated using 100 fecal samples from patients with diarrhea and 150 diarrheagenic E. coli strains isolated in Korea. In conclusion, the multiplex PCR assay developed in this study is very useful for the rapid and specific detection of five diarrheagenic E. coli types. This single-step assay will be useful as a rapid and economical method, as it reduces the cost and time required for the identification of diarrheagenic E. coli.

• 한국HCI학회:학술대회논문집
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• 2006.02b
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• pp.175-178
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• 2006

1990 년대부터 본격적으로 시작된 국내 휴대폰의 역사는 불과 10 년 사이에 전체 인구 중 3600 만명 이상의 가입자가 휴대폰을 사용하고 있는 모바일 강국으로 발전하였다. 국내 이동통신사들의 다양한 서비스 전략과 단말 제조사들의 다양한 기술의 발전으로 휴대폰은 단순한 전화기능만을 담당하는 커뮤니케이션 디바이스(Communication Device)에서 다양한 VOD, AOD 서비스들의 도입으로 엔터테인먼트 디바이스(Entertainment Device)로 발전했고, DMB, TV, MP3, 카메라 등 다양한 디바이스들이 결합된 컨버전스 기능성 기기(Functional Device)로 발전해 가고 있다. 이런 과정에서 사용자들은 휴대폰에서 다양한 경험을 하게 된다. 본 연구는 다양한 매체와 디바이스가 결합 된 모바일 환경 속에서 이동통신사와 제조사의 관점에서 분석한 자료를 바탕으로 하나의 통합된 경험을 사용자들에게 제공할 수 있는 방법을 고찰해 보고자 한다. 휴대폰을 만드는 제조업체가 수행하는 경험 디자인은 이동통신사에 상관없이, 자사의 경험 통일성(identity)을 강조하게 되고, 이동통신사는 제조업체와 상관없이 자사의 경험 통일성을 강조하게 된다. 통일성 뿐만 아니라 기능이나 직무(task)의 중요성도 다르기 때문에 경험 디자인을 위한 우선순위도 다르게 된다. 이것의 결과는 모두 사용자가 떠 앉게 된다. 즉 사용자의 경험이 복잡해지게 되고 이것은 장기적으로 제조업체 및 이동통신사 모두에게 불이익을 주게 된다. 본 논문에서는 제조사와 이통사를 위한 사용자 경험 모형을 세웠고, 각 요소별로 접근 방법의 차이에 대해 논의를 하였다. 사용자가 휴대폰 경험에서 혼돈을 적게 하기 위해서는 제조사와 이통사의 인터랙션은 서로 일관성이 있어야 하고, 스타일 부문에서는 서로간의 입장차이가 좁히기 쉽지 않으므로 둘 다 사용자의 선택의 폭을 넓혀주는 방향으로 진행을 한다. 기획단계에서 부터 협력을 함으로써 양사의 갭을 줄일 수 있다.

• Proceedings of KOSOMES biannual meeting
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• 2006.11a
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• pp.253-258
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• 2006

This paper aims to measure and evaluates the technical efficiency with two inputs and four outputs with the use of fuzzy DEA(Data Envelopment Analysis) in Korean RCC(Rescue Co-ordination Center)/RSC(Rescue Sub-Center). Especially, this paper included not only the marine accident data which occurred for the analysis in particular but also the possibility data of a potential marine accident by an Environmental Stress value and analyzed the technical efficiency. And in this paper, asymmetrical triangular fuzzy number is presented about inputs/ outputs data and a procedure is suggest for it solution. The basic idea is to transform the fuzzy CCR model into a crisp linear programming problem by applying an alternative ${\alpha}-cut$ approach. Also this paper propose a ranking method for fuzzy RCC/RSC using presented fuzzy DEA approach. The result, when ${\alpha}-cut$ is 0.5, efficiency priority should be in order to YS, BS, MP, TS, JJ, PH, US, IC, SC, DR, GS, TA, WD RCC/RSC. Finally, Inefficiency TA, WD RCC/RSC have to benchmarking with reference sets.

• Journal of the Korean Society of Marine Environment & Safety
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• v.13 no.3
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• pp.207-212
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• 2007

This paper aims to measure and evaluate the technical efficiency with two inputs and four outputs with the use of fuzzy DEA in Korean RCC/RSC. Especially, this paper included not only the marine accident data which occurred for the analysis in particular but also the possibility data of a potential marine accident by an Environmental Stress value and analyzed the technical efficiency. And in this paper, asymmetrical triangular fuzzy number is presented about inputs/ outputs data and a procedure is suggested for it's solution. The basic idea is to transform the fuzzy CCR model into a crisp linear programming problem by applying an alternative ${\alpha}$-cut approach. Also this paper propose a ranking method for fuzzy RCC/RSC using presented fuzzy DEA approach. The result, when ${\alpha}$-cut is 0.5, efficiency priority is found in the order of YS, BS, MP, TY, JJ, PH, US, IC, SC, DH, GS, TA, WD RCC/RSC. Finally, Inefficiency TA, WD RCC/RSC have to benchmarking with reference sets.

• Journal of Life Science
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• v.23 no.12
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• pp.1516-1524
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• 2013

To find a novel skin whitening agent, the effect of cordycepin-enriched Cordyceps militaris (CM${\alpha}$) extract fermented by fungi on anti-melanogenesis in B16F0 mouse melanoma cells was investigated. Fermented CM${\alpha}$ was prepared with fungi, including Monascus purpureus (Mp), Aspergillus oryzae (Ao), Aspergillus kawachii (Ak), and Rhizopus oryzae (Ro), respectively. When the content of the phenolics and the flavonoids and the activities of the antioxidant and the mushroom tyrosinase inhibition were measured in the CM fermented by Ak (AkF-CM), the highest content of the phenolics was 46 mg/g dry weight and the highest content of the flavonoids was 0.93 mg/g; the highest activity of the DPPH radical scavenging was 62.74% and the highest activity of the mushroom tyrosinase inhibition was 79.97% CM${\alpha}$CM${\alpha}$. From this result, AkF-CM${\alpha}$ exhibited the highest mushroom tyrosinase inhibitory activity and so it was used in subsequent anti-melanogenesis. B16F0 melanoma cells were treated with 1-10 mg/ml concentrations of AkF-CM${\alpha}$ and 200 ${\mu}M$ arbutin as the positive control. The melanin content and cell viability of the melanoma cells by arbutin treatment decreased to 43% and 92% of the control, respectively. AkF-CM${\alpha}$ treatment at 1, 3, and 5 mg/ml concentrations decreased the extracellular melanin release induced by IBMX treatment by 35%, 45%, and 53%, respectively. AkF-CM${\alpha}$ showed inhibitory activity against both intracellular tyrosinase in melanoma cells and mushroom tyrosinase. AkF-CM${\alpha}$ reduced the protein level of tyrosinase in the IBMX-stimulated cells. These results indicate that AkF-CM${\alpha}$ suppressed the activity and protein content of cellular tyrosinase and decreased the total melanin content in cultured B16F0 melanoma cells.