• Title/Summary/Keyword: CoAP

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Keyhole Imaging Combined Phase Contrast MR Angiography Technique (Keyhole Imaging기법을 적용한 위상대조도 자기공명 혈관조영기법)

  • Lee, D.H.;Hong, C.P.;Han, B.S.;Lee, M.W.
    • Journal of Biomedical Engineering Research
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    • v.33 no.2
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    • pp.72-77
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    • 2012
  • Phase Contrast MR Angiography(PC MRA) is excellent MRA technique for measuring the velocity of vessels in the human body. PC MRA need to at least four images for angiogram reconstruction and it caused longer scan time. Therefore, we used keyhole imaging combined PC MRA to reduce the scan time. However, keyhole imaging can lead the erroneous effects as loss of phase information or frequency discontinuous. In this study, we applied the keyhole imaging combined 2D PC MRA for improving the temporal resolution and also measured the velocity to evaluate the accuracy of phase information. We used 0.32T MRI scanner(Magfinder II, Scimedix, Korea). Using the 2D PC MRA pulse sequence, the vascular images for a human brain targeted on the Superior Sagittal Sinus(SSS) were obtained. We applied tukey window function for keyhole images to minimize the ringing artifact and erroneous factors that are induced frequency discontinuous and phase information loss. We also applied zero-padded algorithm to peripheral missing k-space lines to compare keyhole imaging results and the artifact power(AP) value was measured on the complex difference images to validate the image quality. Consider as based on our results, heavy image distortions and artifacts were shown until using at least 50% keyhole factor. Using above the 50% keyhole factors are shown well reconstructed and matched for magnitude images and velocity information measurements. In conclusion, we confirmed the image quality and velocity information of keyhole technique combined 2D PC MRA. Especially, measured velocity information through the keyhole imaging combination was similar to the velocity information of full sampled k-space image despite of frequency discontinuous and phase information loss in the keyhole imaging reconstruction process. Consequently, the keyhole imaging combined 2D PC MRA will give some clinical usefulness and advantages as improving the temporal resolution and measuring the velocity information via selecting the appropriate keyhole factor at low tesla MRI system.

Effects of Chlorhexidine digluconate on Rotational Rate of n-(9-Anthroyloxy)stearic acid in Model Membranes of Total Lipids Extracted from Porphyromonas gingivalis Outer Membranes

  • Jang, Hye-Ock;Kim, Dong-Won;Kim, Byeong-Ill;Sim, Hong-Gu;Lee, Young-Ho;Lee, Jong-Hwa;Bae, Jung-Ha;Bae, Moon-Kyoung;Kwon, Tae-Hyuk;Yun, Il
    • The Korean Journal of Physiology and Pharmacology
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    • v.8 no.2
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    • pp.83-88
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    • 2004
  • The purpose of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Large unilamellar vesicles (OPGTL) were prepared with total lipids extracted from cultured Porphyromonas gingivalis outer membranes (OPG). The anthroyloxy probes were located at a graded series of depths inside a membrane, depending on its substitution position (n) in the aliphatic chain. Fluorescence polarization of n-(9-anthroyloxy)stearic acid was used to examine effects of chlorhexidine digluconate on differential rotational mobility, while changing the probes' substitution position (n) in the membrane phospholipids aliphatic chain. Magnitude of the rotational mobility of the intact six membrane components differed depending on the substitution position in the descending order of 16-(9-anthroyloxy)palmitic acid (16-AP), 12, 9, 6, 3 and 2-(9-anthroyloxy)stearic acid (12-AS, 9-AS, 6-AS, 3-AS and 2-AS). Chlorhexidine digluconate increased in a dose-dependent manner the rate of rotational mobility of hydrocarbon interior of the OPGTL prepared with total lipids extracted from cultured OPG, but decreased the mobility of membrane interface of the OPGTL. Disordering or ordering effects of chlorhexidine digluconate on membrane lipids may be responsible for some, but not all of its bacteriostatic and bactericidal actions.

Differential Mechanisms of Vascular Relaxation between Alcohol Steamed Rhei Tangutici Radix et Rhizoma and Rhei Tangutici Radix et Rhizoma (당고특대황(唐古特大黃)의 주증(酒蒸) 여부가 혈관이완 기전에 미치는 영향)

  • Yang, Jae-Kyung;Shin, Heung-Mook
    • The Korea Journal of Herbology
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    • v.25 no.4
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    • pp.17-21
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    • 2010
  • Objectives : The aim of this study was to evaluate the differential mechnism of vasodilation of alcohol steamed Rhei Tangutici Radix et Rhizoma. (ART) and Rhei Tangutici Radix et Rhizoma. (RT) in rat thoracic aorta. Methods : Rat aortic ring preparations were mounted in organ baths with oxygenated (95% $O_2$-5% $CO_2$) Krebs-Ringer bicarbonate solutions at $37{\pm}0.5^{\circ}C$ and subjected to contractions or relaxations. Results : ART exerted vasorelaxation on phenylephrine(PE)-induced contraction in a dose dependent manner. Vasorelaxation effects of ART and RT were endothelium-independent. In the $Ca^{2+}$-free high KCl (60 mM) baths, the contraction of aortic rings induced by accumulative addition of $Ca^{2+}$ (0.3-10.0 mM) was significantly reduced by pre-treatment with both ART and RT for 10 min. The magnitude of vasodilatation was biggerin ART. Moreover, verapamil ($0.001{\mu}M$) and diltiazem ($10{\mu}M$), voltage operative $Ca^{2+}$channel blockers, attenuated the relaxation effect of ART but not that of RT. In the absence of extracellular $Ca^{2+}$, pre-incubation of the aortic rings with RT ($1.0mg/m{\ell}$) significantly reduced the contraction caused by PE but not that of ART. $K^+$ channel inhibitors such as glibenclamide (Gli, $10^{-5}M$), tetraethylammonium (TEA, 1 mM) and 4-aminopyridine (4-AP, 0.2 mM) significantly reduced the ART's vasorelaxation efficacy, but not that of RT. However, the relaxation effects of ART and RT were not inhibited by pre-treatment with indomethacin ($10^{-5}M$), and atropine ($10^{-6}M$). Conclusions : These results suggest that the endothelium-independent relaxation is due to inhibition of $Ca^{2+}$ influx via the suppression of $Ca^{2+}$ release from intracelluar store in RT but via both voltage operative $Ca^{2+}$channel blockage and $K^+$ channel activation in ART.

Performance Analysis of Intake Screens in Power Plants on Mass Impingement of Marine Organisms (발전소 취수구에 대량으로 유입하는 해양생물에 대한 스크린 설비의 성능분석)

  • Lee, Jae-Hac;Choi, Hyun-Woo;Chae, Jin-Ho;Kim, Dong-Sung;Lee, Seung-Baek
    • Ocean and Polar Research
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    • v.28 no.4
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    • pp.385-393
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    • 2006
  • Screening performance of the existing intake screens (drum and travelling screen) on mass impingement of marine animals, a euphausiid, Euphausia pacifica and a scyphozoan medusae, Aurelia aurita that have often clogged intake screens of the Uljin Nuclear Power Plant, was tested. The maximum tolerable densities of marine animals in the inflowing seawater upon the screen were estimated with two different approaches. First the maximum density of jellyfish was calculated from (1) passing amount of seawater per unit time through the screens and (2) the covered area of animals on the screens clogged. The maximum density of krill tolerable in the drum screen was cited from a simulated record of Uljin NPP, then those in the travelling screens were also calculated using the data of drum screen and ratio of seawater amount passing through the screens under the condition of 0.5m water column (W.C.) of the differential pressure (AP) produced by screens, an established permissible limit of ${\Delta}P$. Secondly, the screening performances were also tested by hydrodynamic measurements with various screen models in a circulating water channel equipped with a speed-controlling pump and a differential pressure gauge. From the first approach, the maximum tolerable densities of drum and travelling screen were calculated as 2.0 and $1.5ind/m^3$ for the Jellyfish and 900 and $680ind./m^3$ for the euphausiid, respectively. These densities estimated from the second approach were 2.1 and $0.8ind/m^3$ for the jellyfish and 1059 and $504ind/m^3$ for the euphausiid, respectively. These estimates were compared with the data from historic clogging events to evaluate the practical performance of these intake screens. The comparisons suggest a newly improved intake-screen of which performance should be at least seven times (approximately) better than the existing ones ior the krill and 3.2 times for the jellyfish, respectively, for preventing mass impingement, and for maintaining the condition of the differential pressure between the screens below 0.3 m W.C.

Evaluation of Various Scaffolds for Tissue Engineered Biodisc Using Annulus Fibrosus Cells (조직공학적 바이오디스크의 섬유륜 재생을 위한 지지체 특성평가)

  • Ha, Hyun-Jung;Kim, Soon-Hee;Yoon, Sun-Jung;Park, Sang-Wook;So, Jung-Won;Kim, Moon-Suk;Rhee, John-M.;Khang, Gil-Son;Lee, Hai-Bang
    • Polymer(Korea)
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    • v.32 no.1
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    • pp.26-30
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    • 2008
  • This study was designed to investigate the effect of hybridization of synthetic/natural materials for annulus fibrosus (AF) tissue regeneration in vitro and in vivo. The synthetic/natural hybrid scaffolds were prepared using PLGA (poly (lactic-co-glycolic) acid), SIS (small intestinal submucosa) and DBP (demineralized bone particles). PLGA, PLGA/SIS(20%), PLGA/DBP(20%) and PLGA/SIS (10%)/DBP (10%) scaffold were manufactured by solvent casting/salt leaching method. Compressive strength was measured. Rabbit AF cells were isolated, cultured and seeded into experimental groups. Hydroxyproline production and DNA quantity of AP cells on each scaffold was measured at 2, 4 and 6 weeks after in vitro culture. Cell-scaffold composites were implanted subcutaneously into athymic mice. After 1,4 and 6 weeks postoperatively, specimens were taken and H&E, Safranin-O and type I collagen staining were carried out concerning formation of cartilagenous tissue. In vitro PLGA/SIS scaffold was evaluated for total collagen content (bydroryproline/DNA content) and PLGA scaffold was evaluated for compressive strength.

A Study on the Considerations for Constructing RDA Application Profiles (RDA 응용 프로파일 구축시 고려사항에 관한 연구)

  • Lee, Mihwa
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.30 no.4
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    • pp.29-50
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    • 2019
  • This study was to suggest the considerations for application profiles of 2019 revised RDA using literature reviews and case studies according to new RDA that revised in order to reflect the LRM and linked data. First, the additional elements were recommended as the contents of application profiles such as inverse element, broader element, narrow element, domain, range, alternate label name, mapping to MARC, mapping to BIBFRAME, and RDA description examples as new elements as well as element name, element ID, element URL, description method, vocabulary encoding scheme, data provenance element, data provenance value, and notes as the elements that were already suggested by previous researches. Second, RDA rules' representations in forms of flow chart and application profiles through analyzing RDA rules were suggested in order to apply the rules to RDA application profiles to structure the rules in which every element has 4 types of description method, many conditions, and options. Third, the RDA mapping to BIBFRAME was suggested in RDA application profiles because RDA and BIBFRAME are co-related in context of content standard and encoding format, and mapping BIBFRAME and RDA is necessitated for programming BIBFRAME editors with RDA as content standard. This study will contribute to find the methods for constructing RDA application profiles and BIBFRAME application profiles with RDA as content standard.

An Experimental Study on the Flexural Behavior of Slab Repaired and Reinforced with Strand and Polymer Mortar (강연선과 폴리머 모르타르에 의해 보수보강된 슬래브의 휨거동에 대한 실험적 고찰)

  • Yang Dong-Suk;Hwang Jeong-Ho;Park Sun-Kyu
    • Journal of the Korea Concrete Institute
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    • v.17 no.2 s.86
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    • pp.171-177
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    • 2005
  • Even though the cost associated with the repair and rehabilitation of existing structures are rapidly increasing, vast number of the repaired and rehabilitated structures do not function properly as expected during their remaining service lives. This paper focused on the flexural behavior of reinforced concrete slabs repaired and reinforced by PS strand and polymer mortar in the tension face. The slabs have the size of 700${\times}120{\times}$2200 m and 700${\times}120{\times}$1300 mm. Variables of experiment were space of strengthening, chipping, the number of strand, the kind of mortar in this experimental study. Attention is concentrated upon overall bending capacity, deflection, ductility and failure mode of repaired and reinforced slabs. Test results show that deflection of repaired and reinforced slabs reduced to approximately $40 \%$ comparison to standard slabs. Boundary cracking of chipping slab started ultimate load afterward. Concrete-mortar interface cracked 64.5 kN in repaired slab with AP mortar and 36.0 kN in repaired slab with general polymer mortar. Reinforcement effect increased with reducing space of strand. Also, Reinforcement effects are more by strand than by polymer mortar.

A Study on the Changes in Heavy Metal Emissions when Using Mixed Fuel in a Thermal Power Plant (화력발전소의 혼합연료 사용에 따른 중금속 배출량 변화 연구)

  • Song, Youngho;Kim, Ok;Park, Sanghyun;Lee, Jinheon
    • Journal of Environmental Health Sciences
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    • v.44 no.1
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    • pp.63-75
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    • 2018
  • Objectives: The aim of this research is to explore the total heavy metals from a coal-fired power plant burning bituminous coal with wood pellets due to the implementation of the Renewable Portfolio Standard policy (RPS, 10% of electricity from renewable energy resources by 2023). Methods: The research was carried out by collecting archival data and using the USEPA's AP-42 & EMEP/EEA compilation of emission factors for use in calculating emissions. The Monte Carlo method was also applied for carrying out the calculations of measurement uncertainty. Results: In this paper, the results are listed as follows. Sb was measured at 110 kg (2015) and calculated as 165 kg (2019) and 201 kg (2023). Cr was measured at 1,597 kg (2015) and calculated as 1,687 kg (2019) and 1,728 kg (2023). Cu was measured at 2,888 kg (2015) and calculated as 3,133 kg (2019) and 3,264 kg (2023). Pb was measured at 2,580 kg (2015) and calculated as 2,831 kg (2019) and 2,969 kg (2023). Mn was measured at 3,011 kg (2015) and calculated as 15,034 kg (2019) and 23,014 kg (2023). Hg was measured at 510 kg (2015) and calculated as 513 kg (2019) and 537 kg (2023). Ni was measured at 1,720 kg (2015) and calculated as 1,895 kg (2019) and 1,991 kg (2023). Zn was measured at 7,054 kg (2015) and calculated as 9,938 kg (2019) and 11,778 kg (2023). Se was measured at 7,988 kg (2015) and calculated as 7,663 kg (2019) and 7,351 kg (2023). Conclusion: This shows that most heavy metals would increase steadily from 2015 to 2023. However, Se would decrease by 7.9%. This analysis was conducted with EMEP/EEA's emission factors due to the limited emission factors in South Korea. Co-firewood pellets in coal-fired power plants cause the emission of heavy metals. For this reason, emission factors at air pollution control facilities would be presented and the replacement of wood pellets would be needed.

The Risk Assessment of Carbon Monoxide Poisoning by Gas Boiler Exhaust System and Development of Fundamental Preventive Technology (가스보일러 CO중독 위험성 예측 및 근원적 예방기술 개발)

  • Park, Chan Il;Yoo, Kee-Youn
    • Journal of the Korean Institute of Gas
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    • v.25 no.3
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    • pp.27-38
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    • 2021
  • We devised the system to automatically shutdown the boiler and to fundamentally block the harmful gases, including carbon monoxide, into the indoor when the exhaust system swerves: (1) The discharge pressure of the exhaust gas decreases when the exhaust pipe is disconnected. The monitoring system of the exhaust pipe is implemented by measuring the output voltage of APS(Air Pressure Sensor) installed to control the amount of combustion air. (2) The operating software was modified so that when the system recognizes the fault condition of a flue pipe, the boiler control unit displays the fault status on the indoor regulator while shutting down the boiler. In accordance with the ventilation facility standards in the "Rules for Building Equipment Standards" by the Ministry of Land, Infrastructure and Transport, experiments were conducted to ventilate indoor air. When carbon monoxide leaked in worst-case scenario, it was possible to prevent poisoning accidents. However, since 2013, the number of indoor air exchange times has been mitigated from 0.7 to 0.5 times per hour. We observed the concentration exceeding TWA 30 ppm occasionally and thus recommend to reinforce this criterion. In conclusion, if the flue pipe fault detection and the indoor air ventilation system are introduced, carbon monoxide poisoning accidents are expected to decrease significantly. Also when the manufacturing and inspection steps, the correct installation and repair are supplemented with the user's attention in missing flue, it will be served to prevent human casualties from carbon monoxide poisoning.

A Security Nonce Generation Algorithm Scheme Research for Improving Data Reliability and Anomaly Pattern Detection of Smart City Platform Data Management (스마트시티 플랫폼 데이터 운영의 이상패턴 탐지 및 데이터 신뢰성 향상을 위한 보안 난수 생성 알고리즘 방안 연구)

  • Lee, Jaekwan;Shin, Jinho;Joo, Yongjae;Noh, Jaekoo;Kim, Jae Do;Kim, Yongjoon;Jung, Namjoon
    • KEPCO Journal on Electric Power and Energy
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    • v.4 no.2
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    • pp.75-80
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    • 2018
  • The smart city is developing an energy system efficiently through a common management of the city resource for the growth and a low carbon social. However, the smart city doesn't counter a verification effectively about a anomaly pattern detection when existing security technology (authentication, integrity, confidentiality) is used by fixed security key and key deodorization according to generated big data. This paper is proposed the "security nonce generation based on security nonce generation" for anomaly pattern detection of the adversary and a safety of the key is high through the key generation of the KDC (Key Distribution Center; KDC) for improvement. The proposed scheme distributes the generated security nonce and authentication keys to each facilities system by the KDC. This proposed scheme can be enhanced to the security by doing the external pattern detection and changed new security key through distributed security nonce with keys. Therefore, this paper can do improving the security and a responsibility of the smart city platform management data through the anomaly pattern detection and the safety of the keys.