• Title/Summary/Keyword: Co-exposure

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Initial Risk Assessment of Benzoyl Peroxide in OECD High Production Volume Chemical Program

  • Heekyung Bae;Kim, Su-Hyon;Kim, Mi-Kyoung;Sanghwan Song;Hyunju Koo;Lee, Moon-Soon;Jeon, Seong-Hwan;Na, Jin-Gyun;Park, Kwangsik
    • Proceedings of the Korea Society of Environmental Toocicology Conference
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    • 2003.10a
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    • pp.160-161
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    • 2003
  • In Korea, 1, 357 tonnes of benzoyl peroxide was produced as a white granule with purities ranging 22 to 95% in 2001. 75% of benzoyl peroxide is mainly used in the manufacture of expandable styrene polymer and other resins as initiators of polymerization and also been used in the treatment of acne vulgaris and the medical product contains mainly 5 to 10% of it. A very small portion of benzoyl Peroxide is used as flour bleaching agent, Potential human exposure from workplaces is expected to be negligible because this chemical is produced in closed system in only one company in Korea and when a production facility monitors its workplace for the worker exposure annually, the concentration of airborne aerosols at the personal sampling has been less than 1mg/㎥.

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Estimating MOE of Thermal Degraded Wood by Stress Wave Method (Stress wave법에 의한 열적 열화된 목재의 휨탄성계수 예측)

  • Lee, Jun-Jae;Kim, Jeong-Won
    • Journal of the Korean Wood Science and Technology
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    • v.26 no.3
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    • pp.9-15
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    • 1998
  • The strength and stiffness of structures would be weakened by thermal degradation of wood members which are exposed to a variety of heat including a fire. For this reason, thermal degraded wood members can't pertinently support the load. However, it is easy to repair or rehabilitate wood structures. So, the degraded wood members which can't support the load can be replaced with new members. For the sake of this advantage, there is a need for nondestructive evaluation(NDE) technique, which is very effective to assess wood members in service. In this paper, it was considered whether the stress wave method is adequate to estimate static bending MOE of thermal degraded wood. As the result, the relationship between static bending MOE and MOEsw in elevated temperature was found out significant. Therefore, the application of stress wave method for estimating static bending MOE of thermal degraded zzwood would be possible. However, it is thought that further research for the effects of exposure temperature, time, and thermal degradation on the relationship between static bending MOEb and MOEsw would be needed.

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Auto Exposure control system for Compact Image Sensor Module (콤팩트 이미지 센서모듈을 위한 자동 노출제어 시스템)

  • Kim, Hyun-Sik;Jang, Won-Woo;Song, Jin-Gun;Kim, Kang-Joo;Kang, Bong-Soon
    • Proceedings of the Korea Institute of Convergence Signal Processing
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    • 2006.06a
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    • pp.13-16
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    • 2006
  • 사진을 찍을 때 카메라는 보기 좋은 사진을 얻을 수 있도록 많은 기능을 제공하고 있다. 대표적인 기능으로 자동 초점거리 조정(Auto Focus), 자동 색온도 보정(Auto White Balance), 자동 노출 조정(Auto Exposure)이 있다. 본 논문에서는 편리한 기능들 중 하나로써 자동 노출제어 시스템을 구현하였다. 본 논문에서 제안하는 자동 노출제어 시스템은 가변 시상수(Variable Time Constant)를 가지는 IIR 필터를 이용한다. Zone System에서 보여주는 사물의 휘도정보를 바탕으로 하여 이상적인 영상의 휘도 특성 그래프를 얻어내고, 이와 현재의 노출설정에서 휘도와 비교하여 적정 노출을 찾는다. 제안하는 자동 노출제어 시스템은 적정 노출을 얻을 수 있는 위치로 이동하기 위하여 기존의 마이크로 콘트롤러 등을 이용하여 구현하는 방법과 달리 간단한 구성을 가지는 IIR 필터를 이용한다. 제안하는 자동 노출제어 시스템은 간단한 구성을 가지므로 콤팩트 이미지 센서를 구성하기 위하여 사용 할 수 있다.

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Stage System for LCD Exposure Equipment Using Touch-type Displacement Sensor (접촉형 변위센서를 이용한 LCD노광기용 스테이지 시스템)

  • Yim, Kwang-Kuk;Seo, Hwa-Il;Cho, Hyun-Chan;Kim, Kwang-Sun;Kang, Heung-Seok
    • Journal of the Semiconductor & Display Technology
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    • v.6 no.1 s.18
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    • pp.7-10
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    • 2007
  • In an effort to reduce weaknesses of existing laser displacement sensor-based system, a sensing device for distance and balance of mask-substrate gap using touch-type displacement sensor was suggested. The device suggested in this study is expected to solve the problems of prices and reflections, by means of a touch-type sensor. LCD exposure equipment stage system including suggested sensing device was realized to assess the characteristics of sensing the balance and gap between mask and substrate. It was verified that a touch-type displacement sensor-based device to adjust the balance and distance of mask-substrate gap suggested in this study can be applicable to LCD expose equipment in practice.

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Short-term Toxicity Assay Based on Daphnid Feeding on the Microalga Scenedesmus subspicatus

  • Lee Sang-Ill;Park Jong-Ho;Lee Won-Ho;Yeon Ik-Jun;Lee Byoung-Chan;Cho Kyu-Seok;Choi Hyun-Ill
    • Fisheries and Aquatic Sciences
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    • v.9 no.1
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    • pp.38-43
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    • 2006
  • We developed and evaluated a method of short-term acute toxicity testing based on the feeding behavior of Ceriodaphnia dubia. In prior toxicity tests, neonates of C. dubia were hatched and cultivated with the addition of yeast only for the preparation of the transparent daphnid's gut. Scenedesmus subspicatus was supplied as food after 1 to 6 h of exposure to toxicants. The effects of 1-h and 6-h exposure time on test sensitivity did not significantly differ. A comparison of the short-term l-h acute toxicity test developed in this study to the standard 48-h acute toxicity test using heavy metals, cyanide, and pentachlorophenol indicated that the 1-h test provided an acceptable sensitivity level in toxicity testing of C. dubia..

Methyl-Tertiary Butyl Ether(MTBE) and BTEX Inside and Outside Apartments with Different Construction Age

  • Jo, Wan-Kuen;Lee, Jong-Hyo
    • Journal of Environmental Science International
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    • v.19 no.1
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    • pp.1-8
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    • 2010
  • Only limited information is available on the measured exposure levels of residents according to the construction age of apartments. As such, present study was conducted to measure and to compare the bedroom, living-room, and outdoor air levels of MTBE and benzene, toluene, ethyl benzene and m,p-xylene(BTEX) in both newer and older apartments. For both newer and older apartments, all the compounds except for MTBE showed significantly higher levels in bedrooms or living-rooms as compared to the outdoor concentrations. The ratio of bedroom or living-room median concentration to outdoor concentration was close to 1 for MTBE, whereas it was larger than 1 for other target compounds. It was also found that the bedroom and living-room appeared to have similar indoor sources and sinks for BTEX, but not for MTBE. The median concentration ratios of the newer apartments to the older apartments ranged from 1.63 to 1.81, depending upon the compounds. In contrast, the MTBE concentrations did not differ significantly between the newer and older apartments, thereby suggesting that although newer buildings could emit more VOCs, this is not applicable to all VOCs. Conclusively, the findings of present study should be considered, when designing exposure studies associated with VOC emissions in buildings and/or managing indoor air quality according to construction age of buildings.

Investigation of physical characteristics for Al2O3:C dosimeter using LM-OSL

  • Kim, Myung-Jin;Lee, Young-Ju;Kim, Ki-Bum;Hong, Duk-Geun
    • Analytical Science and Technology
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    • v.32 no.4
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    • pp.131-138
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    • 2019
  • This paper reports results on the physical properties of a powder type of $Al_2O_3:C$ commonly used as a luminescence dosimeter using the LM-OSL technique. On the analysis with the general order kinetics model, the LM-OSL signal measured appeared to be composed of three components (fast, medium, slow) showing the largest area in the medium component. The photoionization cross sections of three components were distributed between $10^{-19}{\sim}10^{-21}cm^2$. The values of the thermal assistance energy were evaluated the largest in slow component and the smallest in fast component, which indicates the electrons trapped in defects attributed to slow component should be the most sensitive to thermal vibration among three components. In illumination to blue light, the fast component showed a rapid linear decay and completely disappeared after light exposure time of about 5 s. The medium component decayed with two exponential elements but the slow component did not observed any noticeable change until light exposure time of 40 s. In a dose response study, all components exhibited a linear behaviour up to approximately 10 Gy.

Ibuprofen Increases the Hepatotoxicity of Ethanol through Potentiating Oxidative Stress

  • Kim, Minjeong;Lee, Eugenia Jin;Lim, Kyung-Min
    • Biomolecules & Therapeutics
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    • v.29 no.2
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    • pp.205-210
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    • 2021
  • Over 30 million prescriptions of NSAIDs (non-steroidal anti-inflammatory drugs) are issued every year. Considering that these drugs are available without a prescription as over the counter (OTC) drugs, their use will be astronomical. With the increasing use of NSAIDs, their adverse effects are drawing attention. Especially, stomach bleeding, kidney toxicity, liver toxicity, and neurological toxicity are reported as common. Ibuprofen, one of the extensively used NSAIDs along with aspirin, can also induce liver toxicity, but few studies are addressing this point. Here we examined the liver toxicity of ibuprofen and investigated whether co-exposure to ethanol can manifest synergistic effects. We employed 2D and 3D cultured human hepatoma cells, HepG2 to examine the synergistic hepatotoxicity of ibuprofen and alcohol concerning cell viability, morphology, and histology of 3D spheroids. As a result, ibuprofen and alcohol provoked synergistic hepatotoxicity against hepatocytes, and their toxicity increased prominently in 3D culture upon extended exposure. Oxidative stress appeared to be the mechanisms underlying the synergistic toxicity of ibuprofen and alcohol as evidenced by increased production of ROS and expression of the endogenous antioxidant system. Collectively, this study has demonstrated that ibuprofen and EtOH can induce synergistic hepatotoxicity, providing a line of evidence for caution against the use of ibuprofen in combination with alcohol.

PRACTICAL APPROACHES TO RISK MANAGEMENT FOR GLOBAL CONTRACTORS

  • Seung Heon Han;Du Yon Kim;Han Him Kim
    • International conference on construction engineering and project management
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    • 2005.10a
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    • pp.1231-1236
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    • 2005
  • Global construction projects manifest more risks than do other industries. Often, firms doing business in construction markets find these risks intimidating. To secure corresponding profits, many global contractors attempt to forecast the effects of risks and establish risk management strategies. However, one key problem with present-day risk management methods is that they are basically analytical or mathematical-oriented approaches which are not easy to adopt in real business. Based on preliminary investigations and evaluations of current tools, this research elicits more practical algorithms for risk checklist by constructing risk scenarios over the whole period of project execution. For the application of the algorithms, a "SE/RF" (Source-Event/Regular-Floating) checklist is suggested, which sorts out risk sources and their subsequent events, as well as dividing various risk factors into either regular or floating categories. In addition, the "PIS" (Probability-Impact-Significance) method is introduced, in place of traditional "PI" (Probability-Impact) methods, by adding the additional criterion of "risk significance" to determine the degree of risk exposure in a more realistic way. As a result, we draw the significant finding that the "PIS" method presents a closer evaluation regarding degree of risk exposure as compared to the level of expert judgments than those from traditional methods. Finally, we provide an integrated procedure for international project risk management with all of the research achievements being incorporated.

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Biological indicator on radiation exposure using apoptosis in adult and newborn mice (성숙 및 신생마우스에서 아포프토시스를 이용한 방사선 피폭의 생물학적 지표)

  • Oh, Heon;Lee, Song-eun;Yang, Jung-ah;Jeong, Kyu-shik;Hyun, Byung-hwa;Kim, Sung-ho
    • Korean Journal of Veterinary Research
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    • v.38 no.4
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    • pp.679-685
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    • 1998
  • We have studied, by a nonisotopic in situ DNA end-labeling (ISEL) technique, frequency of apoptosis in the external granular layer (EGL) of the cerebellum after whole-body irradiation of newborn mice and intestinal crypt cell of adult mice by gamma-rays from $^{60}Co$. The extent of changes following 2 Gy(10.9 Gy/min) was studied at 2, 4, 6, 8, 12, or 24h after exposure. The maximal frequency was found 4-8h after exposure. The mice that received 0.18, 0.36, 0.54, 1.08, 1.98, or 3.96 Gy were examined 6h after irradiation. Measurements performed after irradiation showed a dose-related increase in apoptotic cells in each of the mice studied. The dose-response curves were analyzed by a linear-quadratic model; frequency(%) of apoptotic cell in the newborn mice cerebellum was ($13.49{\pm}1.175$)D+$(-1.52{\pm}0.334)D^2$+0.048($r^2=0.981$, D = dose in Gy) and frequency(number per crypt) of apoptotic cell in the intestinal crypt of adult mice was ($3.857{\pm}0.420$)D+$(-0.535{\pm}0.120)D^2$+0.155($r^2=0.952$, D = dose in Gy). It provides the basis required for a better understanding of results which will be obtained in any further studies for biological responses of radiation using newborn and adult mice.

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