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The Effect of Low-Intensity Treadmill Exercise on Blood Levels of Glucose, Insulin and Lipids in Streptozotocin-Induced Diabetic Rats (저강도 treadmill 운동이 streptozotocin 유도 당뇨쥐의 혈당, 인슐린 및 지질 농도에 미치는 영향)

  • 김세종;서혜림;고정림;염종우;예정복;이선주;김경환;손원협;장은숙
    • Journal of Life Science
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    • v.14 no.2
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    • pp.245-251
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    • 2004
  • Exercise is beneficial to the diabetic patients and streptozotocin-induced diabetic rat has been used for the study of exercise effect. The purpose of this study was to establish the optimal condition of induction of hyperglycemic diabetic rat using streptozotocin and to examine the preventive effect of treadmill exercise on the diabetic rat before and after streptozotocin injection. Intraperitoneal injection of increasing amount of streptozotocin up to 40 mg/kg dose-responsively induce hyperglycemic diabetic rat and inversely reduced the blood insulin level. Body weight was also gradually reduced with the increasing amount of streptozotocin. Control and diabetic rats exercised for 4 weeks before streptozotocin injection. The exercise was performed in the treadmill for 25 minutes a day and 5 times a week with low intensity (0 degree tilt, 15 m/min velocity). Following streptozotocin injection, the blood glucose level was measured every week and the rat was sacrificed after 4 weeks to measure the concentration of insulin and blood lipids. The blood levels of glucose and insulin was significantly reduced with exercise before streptozotocin injection, while those were not changed after streptozotocin injection. The levels of blood lipids such as total cholesterol, HDL-cholesterol, LDL-cholesterol and triglyceride were close to normal control rats. From this study, researchers found the optimal condition of preparation of streptozotocin-induced hyperglycemic diabetic rat, and the mild treadmill exercise has beneficial effect on preventing hyperglycemia and hyperlipidemia. Thus, even low intensive running prevent not only diabetes but also diabetic vascular complications.

Effects of External Conditions on the Emulsifying Property of Proteins (단백질의 유화작용(乳化作用)에 미치는 외적(外的) 조건(條件)에 관한 연구)

  • Lee, Cherl-Ho;Kim, Hak-Ryang;Yang, Han-Chul;Lee, Myung-Won;Bae, Chong-Chan
    • Korean Journal of Food Science and Technology
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    • v.14 no.1
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    • pp.49-56
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    • 1982
  • The effects of measurement conditions on the emulsifying capacity(EC) and emulsion stability(ES) of proteins were studied in order to develop laboratory standard methods for the evaluation of emulsifying properties. The EC of proteins decreased with the increments of protein concentration and mixing rate. It increased with the increasing oil addition rate up to 0.8 ml/sec, but did not change at $0.8{\sim}1.2\;ml/sec$. The addition of sodiumchloride enhanced EC of proteins, attaining to the highest EC at 0.3M NaCl for Pro-Fam and 0.1M NaCl for Na-caseinate. The ES of Pro-Fam was higher than that of caseinate. The ES was increased by the increments of protein concentration, oil addition volume, mixing rate and mixing time. The EC and ES showed a close relation to the NSI of proteins, reaching to the lowest values of EC and ES at the isoelectric regions of proteins. The laboratory methods for measurements of emulsifying properties of proteins were established. The emulsifying properties of a laboratory-made soybean protein isolate were compared to those of commercial products by using the methods.

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A Landscape Possessor and Enjoyment of Jongho on the Mansutan River Traced by Stone Inscription and 'Jongho Eight Views' (바위글씨와 팔경으로 추적한 만수탄(萬水灘) 종호(鍾湖)의 경관 향유자와 풍류상)

  • Rho, Jae-Hyun;Kim, Hwa-Ok;Park, Yool-Jin;Kim, Hong-Gyun
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.38 no.1
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    • pp.53-66
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    • 2020
  • This study was attempted to seek the garden enjoyment of the Yang Un-geo etc., in the head house(宗宅) of Namwonyang's family and Jongho in Sunchang Gumiri through literature and field research. Admirers of Jongho were "six old Taoist hermit", including Cholo(楚老) Yang Un-geo(楊雲擧, 1613-1672) and Yangjindang Haman-ri, the author of Jongho-palgyeong, who was very close friends of Yang, as well as his son-in-law or out-law. Jonghojeong Pavilion, overland rock and nearby Takyeongjeong, which were built around a stone island shaped like a helmet, and a pool along the river, are known as 'Imcheonwonrim(林泉園林)' as the center of the custom that was conducted based on head house, which is up to 2km away from Jongho. Jongho-palgyeong is found to share the characteristics of Jeongja Palgyeong, which is based on Jonghoam, overland and Takyeongjeong, and the characteristics of the town's township of Namwonyang, Gumi-ri. The number of rock letters identified by the Mansutan members is a total of nine points, which clearly indicates that the scene was a scene where the custom of call to create poetry·fishing·playing musical instruments and drinking, as well as the scenery and landscape structure of the Jongho Palgyeong. Jongho Palgyeong, its customs and surrounding rock writing are highly suggestive and valid cultural views to remind or direct the old landscape of Mansutan Jongho and suggest to modern traditional landscapes as well as the "Noblesse oblige landscape enjoyment case."

Correlation Analysis According to Consumption Trend using Association Rule (연관규칙을 이용한 가구별 소비 트렌드의 상관분석)

  • Choi, Jung-Ah;Jung, Yong-Gyu
    • Journal of Service Research and Studies
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    • v.5 no.1
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    • pp.105-111
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    • 2015
  • According to Korea Social Trends 2012 report presented in National Statistical Office, based on 2010, single-person household out of all households in Korea ratio is 23.9%, not only this ratio is beyond a family of four's ratio (22.5%) but also overtake couple-person household. Last year, according to financial industry and National Statistical Office, Korea's single-person household is estimated 4 million Five hundred and thirty thousand nine thousand family (25.3%). this mean is Korea's One of four household furniture is single-person household. Furthermore. According to National Statistical Office's report 'Future household projections 2010~2035 Report', In 2035, Korea's single-person household is assumed to increase by 34.3%. Korea's causes an increase of single-person household causes an increase is reduced marriage, increase in divorce, low fertility, increasing older singles etc. also Around the World as well as Korea single person household is increase. Based on 2011, single-person household is reached at 2 hundred million 42 million furniture (This ratio is 13%), China and U.S.A's single-person household ratio close in upon 30%. Sweden and Norway, the Philippines, Denmark is also approximately 40% of all households. Up to now, Not reached at OECD average, but this is increasing at a very fast pace. and then It will overtake this ratio. so government, regarding single-person household upsurge, try to find definitive solution. Appeared to statistics through the data, this find out the single-person household characteristics. Using association rule, the association between consumption trend and single-person.

Static and Dynamic Behavior at Low-Frequency Range of Floating Slab Track Discretely Supported by Rubber Mounts in Real-Scale Laboratory Test (고무 마운트로 이산 지지되는 플로팅 슬래브 궤도의 실모형 실내 실험에서의 정적 및 저주파 대역 동적 거동)

  • Hwang, Sung Ho;Jang, Seung Yup;Kim, Eun;Park, Jin Chul
    • Journal of the Korean Society for Railway
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    • v.15 no.5
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    • pp.485-497
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    • 2012
  • Recently, with increasing social interests on noise and vibration induced by railway traffic, the application of floating slab track that can efficiently reduce the railway vibration is increasing. In this study, to more accurately understand the dynamic behavior of the floating slab track, a laboratory mock-up test has been performed, and the static and dynamic behaviors at frequency range near the system resonance frequency were explored. Based on the test results, the design of the floating slab track and the structural analysis model used in the design have been verified. The analytic and test results demonstrate that the dominant frequency of the floating slab track occurs at the frequencies between vertical rigid body mode natural frequency and bending mode natural frequency, and the dominant deformation mode is close to the bending mode. This suggests that in the design of the floating slab track, the bending rigidity of the slab and the boundary conditions at slab joints and slab ends should be taken into consideration. Also, the analytic results by the two-dimensional finite element analysis model using Kelvin-Voigt model, such as static and dynamic deflections and force transmissibility, are found in good agreement with the test results, and thus the model used in this study has shown the reliability suitable to be utilized in the design of the floating slab track.

A Development Plan for Co-creation-based Smart City through the Trend Analysis of Internet of Things (사물인터넷 동향분석을 통한 Co-creation기반 스마트시티 구축 방안)

  • Park, Ju Seop;Hong, Soon-Goo;Kim, Na Rang
    • Journal of Korea Society of Industrial Information Systems
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    • v.21 no.4
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    • pp.67-78
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    • 2016
  • Recently many countries around the world are actively promoting smart city projects to address various urban problems such as traffic congestion, housing shortage, and energy scarcity. Due to development of the Internet of Things (IoT), the development of a smart city with sustainability, convenience, and environment-friendliness was enabled through the effective control and reuse of urban resources. The purpose of this study is to analyze the technical trends of IoT and present a development plan for smart city which is one of the applications of the IoT. To this end, the news articles of the Electronic Times between 2013 and 2015were analyzed using the text mining technique and smart city development cases of other countries were investigated. The analysis results revealed the close relationships of big data, cloud, platforms, and sensors with smart city. For the successful development of a smart city, first, all the interested parties in the city must work together to create new values throughout the entire process of value chain. Second, they must utilize big data and disclose public data more actively than they are doing now. This study has made academic contribution in that it has presented a big data analysis method and stimulated follow-up studies. For the practical contribution, the results of this study provided useful data for the policy making of local governments and administrative agencies for smart city development. This study may have limitations in the incorporation of the total trends because only the news articles of the Electronic Times were selected to analyze the technical trends of the IoT.

State of Visual Acuity Test and Factors Related to Vision Deterioration of Preschoolers (미취학 아동의 시력검진 실태와 시력저하 관련요인)

  • Lee, Sunghwa;Lee, Haejung
    • The Journal of the Korea Contents Association
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    • v.16 no.12
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    • pp.132-142
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    • 2016
  • The study aimed to examine the state of visual acuity tests in preschoolers and determine the factors affecting the deterioration of their vision. A total of 172 pair, child aged 5-7 years and either one of their parents, were recruited from childcare centers or kindergarten between August 2015 and January 2016. Questionnaires were administered to the parents, and the children's visual acuities were measured. Using forward selection in logistics regression analysis, factors affecting vision deterioration were elucidated. Of 172 children, 128 (74.4%) had undergone a visual acuity test previously and 77 (44.8%) showed a deterioration in their vision. Children who had undergone their first visual acuity test after the age of 7 years (OR=7.425, CI=2.844- 19.385) and showed more abnormal eye symptoms, such as squinting or tilting the head to see or falling down frequently (OR=3.084, CI=1.202-7.914) and whose age was younger (OR=10.335, CI=3.252-32.848), were more likely to develop deterioration of vision. Children who had a posture such that they looked up at the computer monitor from below (OR=.075, CI=.022-.255), were less likely to show deterioration of vision. It can be inferred that early visual acuity tests is essential to detect deteriorated vision of preschoolers. Therefore, it is necessary to educate parents, personnels in day care center, and health clinics about the importance of early visual acuity tests and close observation of specific behaviors related to vision deterioration. Development of precautionary intervention program of vision deterioration in preschoolers and examination of its effects are needed.

Generation and Detection of Cranial Landmark

  • Heo, Suwoong;Kang, Jiwoo;Kim, Yong Oock;Lee, Sanghoon
    • Journal of International Society for Simulation Surgery
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    • v.2 no.1
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    • pp.26-32
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    • 2015
  • Purpose When a surgeon examines the morphology of skull of patient, locations of craniometric landmarks of 3D computed tomography(CT) volume are one of the most important information for surgical purpose. The locations of craniometric landmarks can be found manually by surgeon from the 3D rendered volume or 2D sagittal, axial, and coronal slices which are taken by CT. Since there are many landmarks on the skull, finding these manually is time-consuming, exhaustive, and occasionally inexact. These inefficiencies raise a demand for a automatic localization technique for craniometric landmark points. So in this paper, we propose a novel method through which we can automatically find these landmark points, which are useful for surgical purpose. Materials and Methods At first, we align the experimental data (CT volumes) using Frankfurt Horizontal Plane (FHP) and Mid Sagittal Plane(MSP) which are defined by 3 and 2 cranial landmark points each. The target landmark of our experiment is the anterior nasal spine. Prior to constructing a statistical cubic model which would be used for detecting the location of the landmark from a given CT volume, reference points for the anterior nasal spine were manually chosen by a surgeon from several CT volume sets. The statistical cubic model is constructed by calculating weighted intensity means of these CT sets around the reference points. By finding the location where similarity function (squared difference function) has the minimal value with this model, the location of the landmark can be found from any given CT volume. Results In this paper, we used 5 CT volumes to construct the statistical cubic model. The 20 CT volumes including the volumes, which were used to construct the model, were used for testing. The range of age of subjects is up to 2 years (24 months) old. The found points of each data are almost close to the reference point which were manually chosen by surgeon. Also it has been seen that the similarity function always has the global minimum at the detection point. Conclusion Through the experiment, we have seen the proposed method shows the outstanding performance in searching the landmark point. This algorithm would make surgeons efficiently work with morphological informations of skull. We also expect the potential of our algorithm for searching the anatomic landmarks not only cranial landmarks.

Spatial development of manufacturing industry in Chonbuk Province,1975~1999 (전북 제조업의 성장과 공간적 발달)

  • 백영기;김진석
    • Journal of the Economic Geographical Society of Korea
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    • v.3 no.2
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    • pp.5-22
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    • 2000
  • Manufacturing industry in Chonbuk region has experienced relatively consistent increase during period 1975-1999. The importance of labor-intensive sectors such as textiles and clothing, wood and furniture, and food and drink, which had been traditionally major sectors in this region, has declined over the same period. On the other hand, the shares of more complex sectors like automobile, chemistry, communication equipment, and other machinery have gone up. The structural change of Chonbuk manufacturing industry, with increasing diversity, follows the national trend of industrial development, based on national industrial policies. but the speed and level of the change has been slow and low in terms of the national standard of manufacturing development, especially with the weak development of high technology industry. In Chonbuk, the spatial distribution of manufacturing industry has shown a high degree of concentration. Although spatial concentration is apparent in the central area including the cities of Chonju, Iksan, and Kunsan, new tendency towards industrial decentralization within this area has been found. The tendency means manufacturing development at the fringe of this area. There is another tendency towards industrial dispersion into the cities of Kimje and Jeongup close to this central area. The spatial dispersion of manufacturing industry has been accelerated in the form of increasing external investment. But despite the tendency of the spatial dispersion, the development of manufacturing industry in the rest of the region still remains a marked inferiority.

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The Estimated Evacuation Time for the Emergency Planning Zone of the Kori Nuclear Site, with a Focus on the Precautionary Action Zone

  • Lee, Janghee;Jeong, Jae Jun;Shin, Wonki;Song, Eunyoung;Cho, Cheolwoo
    • Journal of Radiation Protection and Research
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    • v.41 no.3
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    • pp.196-205
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    • 2016
  • Background: The emergency planning zone (EPZ) of the city of Busan is divided into the precautionary actions zone (PAZ) and the urgent protective action planning zone; which have a 5-km radius and a 20-km to 21-km radius from the nuclear power plant site, respectively. In this study, we assumed that a severe accident occurred at Shin-Kori nuclear unit 3 and evaluated the dispersion speed of radiological material at each distance at various wind speeds, and estimated the effective dose equivalent and the evacuation time of PAZ residents with the goal of supporting off-site emergency action planning for the nuclear site. Materials and Methods: The total effective dose equivalent, which shows the effect of released radioactive materials on the residents, was evaluated using the RASCAL 4.2 program. In addition, a survey of 1,036 residents was performed using a standardized questionnaire, and the resident evacuation time according to road and distance was analyzed using the VISSIM 6.0 program. Results and Discussion: According to the results obtained using the VISSIM and RASCAL programs, it would take approximately 80 to 252.2 minutes for permanent residents to move out of the PAZ boundary, 40 to 197.2 minutes for students, 60 to 232.2 minutes for the infirm, such as elderly people and those in a nursing home or hospital, and 30 to 182.2 minutes for those temporarily within the area. Consequently, in the event of any delay in the evacuation, it is estimated that the residents would be exposed to up to $10mSv{\cdot}h^{-1}$ of radiation at the Exclusion Area Boundaries (EAB) boundary and $4-6mSv{\cdot}h^{-1}$ at the PAZ boundary. Conclusion: It was shown that the evacuation time for the residents is adequate in light of the time lapse from the initial moment of a severe accident to the radiation release. However, in order to minimize the evacuation time, it is necessary to maintain a system of close collaboration to avoid traffic congestion and spontaneous evacuation attempts.