• Annals of Clinical Neurophysiology
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• 제14권2호
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• pp.86-88
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• 2012

• Journal of Chest Surgery
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• 제16권3호
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• pp.399-404
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• 1983

In general, hiatal hernia is rare incidence among diaphragmatic hernia in Korea especially in pediatric group. Recently great interest in hiatal hernia has not led to common agreement concerning the pathophysiology, method of diagnosis, clinical picture, Indications, and type of treatment. At 1981 and 1983, two cases of congenital hiatal hernia [type I, III] were surgically treated,which surgical Intervention was modified Hill`s operation and gastropexy. Postoperatively, clinical and radiological examination were proved no regurgitation, no dysphagia and well passage of barium.

• 대한유전성대사질환학회지
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• 제12권2호
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• pp.108-112
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• 2012

제 3형 당원병 (Glycogen Storage disease, Type III: OMIM #232400)은 상염색체 열성 유전을 하는 매우 드문 유전 질환으로, 1p21 염색체에 존재하는 AGL 유전자 (OMIM *610860)로부터 전사되는 글리코겐을 분해하는 효소인 가지제거효소(amylo-1,6 Glucosidase; EC 3.2.1.33 and 1,4-${\alpha}$-D-glucan 4-${\alpha}$-D-glycosyltransferase; EC 2.4.1.25)의 결함으로 인해 유발되는 질환이다. 제 3형 당원병의 환자들은 분해되지 못한 글리코겐이 조직에 축적되면서 증상이 발생하는데, 효소가 분포하던 조직에 따라 그 증상은 다양하게 나타난다. 제 3a형 당원병에서 간비대, 저신장, 그리고 저혈당증 증상은 아동기에 주로 나타나나 나이가 들면서 증상이 호전되어 사춘기를 전후하여 정상이 되는 경우가 많으며, 심근병증 및 근무력감, 운동발달지연 등의 근질환 증상은 영아기나 아동기에는 뚜렷하지 않지만 나이가 들면서 심해져 30-40대 이후 성인기에 나타나는 경우가 많다. 저자들은 간비종대, 심근 약화 증상, 근무력증 등의 전형적인 제 3a형 당원병의 임상증상 및 생화학적 특성이 관찰된 25세 여환에게서, AGL 유전자의 분석을 통해 제 3a형 당원병을 확진하였기에 이를 보고하는 바이다.

• 사상체질의학회지
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• 제36권1호
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• pp.13-30
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• 2024

Objectives This study aimed to analyze the influence of various sleep-related factors that affect sleep quality by each Sasang type. Methods A total of 400 subjects were included for this study, 108 males and 292 females. Sasang type was diagnosed using the SCAT. Then, the characteristics of each Sasang type were analyzed using HRV, DITI, and PSQI, PSS, and SDFI questionnaires. Logistic regression analysis was used to predict sleep-related factors that affect sleep disorders by Sasang types. Results This study shows that the pathophysiological characteristics for stress and digestive function of each Sasang type can differentiate sleep management through a logistic regression model including subscales of PSS and SDFI. Stress had no effect on the occurrence of sleep disturbance within only So-Eum, since the stress level is originally high in the So-Eum regardless of sleep quality. Rather, decreased appetite and poor eating habits had a significant impact on the decline in sleep quality. In addition, poor digestion and eating habits in So-Yang had a greater impact and poor digestion in Tae-Eum had a greater impact on the decline in sleep quality. Conclusion The stress and subscales of digestive function provide differentiated sleep management in So-Yang, Tae-Eum, and So-Eum types. The individualized sleep management for each Sasang type with statistically validated PSS and SDFI would be useful for sleep-related experts planning safe and effective person-centered health care as well as for Western clinicians who want to incorporate Sasang typology into their treatments as integrative medical technique in the future.

• 한국임상보건과학회지
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• 제3권2호
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• pp.340-353
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• 2015

Purpose. This study of purpose was to to compare of Aerobic and Anaerobic Capacity between Sasang Constitutions and ACE Gene Polymorphism. Methods. 24 healthy males were participated in this experiment who were in their twenties and had no disease, then they were divided by ACE type and by Sasang constitutions with QSCC II. According to these group, the body compositon, Aerobic capacity including VO2max, Anaerobic Capacity were measured. Results. In this study, According to ACE type, ID type were 8, II were 8 and DD type were 8 persons. According to ACE type, there were significant difference among type, especially, II, ID type more than DD. II type is more higher than any type and DD type is lower in the ratio of Blood Lactic recovery. DD type was more excellent than other type in Anaerobic power. According to Sasang Constitutions, there were 8 SoYang, 5 Taeum, 11 Soeum and then no TaeYang constitution. In Aerobic capacity, Taeum constitution had significantly high means and Anaerobic threshold. In the ratio of Blood lactic recovery, Taeum constitution was excellent and SoYang had poor recovery capacity. SoYang had more excellent than other constitution significantly in Anaerobic capacity. Comparing ACE type with Sasang constitution, Soyang constitution included 4 ID types, Taeum inclued 2 II types and 2 ID types then Soeum included 6 DD types. Compared of Aerobic and Anaerobic capacity between Sasang constitutions and ACE type, Soyang constitutions were similar to ID type, Taeum similar to II type and ID type and then Soeum were DD type. Conclusions. This study had made it clear that there were similar feature between ACE type and Sasang constitutions. Also it's possible to predict the Aerobic capacity that may be foreseen by ACE type with Sasang questionnaire method but not Anaerobic capacity.

• 대한의생명과학회지
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• 제10권4호
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• pp.507-514
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• 2004

The Pseudomonas aeruginosa isolated from the clinical specimens has a mutation on the QRDR (quinolone resistance determining region). There were obvious mutations in both gyrA and parC gene which are major targets of quinolone. Simultaneous mutations were found two sites or more on these genes in all of ten strains. GyrB or parE gene had only silent mutation without converted amino acids. We confirmed that P. aeruginosa from clinical specimens exhibited decreased sensitivity to fluroquiolone due to changed Thr-83→lle and Asp-87→Asn types on gyrA and altered Ser-87→Leu type on parC. This is the first finding that a new Met-93→Thr type on parC as well as mutations on gyrB or parE genes differed from existing patterns. This study showed more mutations of gyrA rather than parC, suggesting that change of Type Ⅳ topoisomerase is more serious than that of type Ⅱ (DNA gyrase).

• 대한한의학방제학회지
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• 제11권1호
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• pp.205-216
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• 2003

A general review is made on Insamyangwitang(人蔘養胃湯). Following conclusions are drawn from the clinical cases of Insamyangwitang in Hyungsang medicine. 1. Insamyangwitang is composed of four different prescriptions of Huisaentang, Sakoonjatang, Eajintang and Pyungwisan. Huisaentang is usually prescribed for the intestinal convulsion. Sakoonjatang for the deficiency of Ki. Eajintang for retention of phlegm. 2. Insamyangwitang is effective in strengthening the spleen, drying the dampness, warning the middle-warmer to stop vomiting, regulating the flow of Ki, and eliminating phlegm. 3. Insamyangwitang is applicable to malaria caused by cold, intestinal convulsion, abdominal mass, edema, tympanites, Yin syndrome of exogenous febrile disease, distension, lack of appetite, stomachache, and diarrhea. 4. Persons with the following characteristic in Hyungsang are more susceptible to Insamyangwitang : Jung type, Hyul type, fish type, Taium meridian type, white fat damp constitution, person with big mouth, and woman rather than man.

• Journal of mucopolysaccharidosis and rare diseases
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• 제2권1호
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• pp.1-4
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• 2016

Mucolipidosis type II (MLII; MIM#252500) and type III alpha/beta (MLIIIA; MIM#252600) very rare lysosomal storage disease cause by reduced enzyme activity of GlcNAc-1-phosphotransferase. ML II is caused by a total or near total loss of GlcNAc-1-phosphotransferase activity whether enzymatic activity in patient with ML IIIA is reduced. While ML II and ML III share similar clinical features, including skeletal abnormalities, ML II is the more severe in terms of phenotype. ML III is a much milder disorder, being characterized by latter onset of clinical symptoms and slower progressive course. GlcNAc-1-phosphotransferase is encoded by two genes, GNPTAB and GNPTG, mutations in GNPTAB give rise to ML II or ML IIIA. To date, more than 100 different GNPTAB mutations have been reported, causing either ML II or ML IIIA. Despite development of new diagnostic approach and understanding of disease mechanism, there is no specific treatment available for patients with ML II and ML IIIA yet, only supportive and symptomatic treatment is indicated.

• Clinical and Experimental Pediatrics
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• 제52권1호
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• pp.6-13
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• 2009

Recent advances in perinatal care have resulted in improved survival of extremely low birth weight infants (ELBWI). However, bronchopulmonary dysplasia (BPD) remains one of the major complications in ELBWI. BPD was originally described over 40 years ago; the clinical characteristics, epidemiology, and pathogenesis of BPD have changed markedly through this period. In this article, I have reviewed recent progress in research concerning the clinical presentation and characteristics, epidemiology, and pathogenesis of BPD.

• 간호행정학회지
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• 제19권4호
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• pp.462-469
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• 2013

Purpose: This study was performed to identify the effects of self-leadership and job involvement on clinical competence in general hospital nurses. Methods: The participants in this study were 443 staff nurses working in general hospitals and having more than 6 months of nursing experience. Data were collected using self-administered questionnaires. Results: There were significant positive correlations between nurses' self-leadership and job involvement, and between nurses' self-leadership and clinical competence. In the multiple regression analysis, clinical career, type of department and self-leadership were significant predictors in explaining nurses' clinical competence and accounted for 28% of the variance in nurses' clinical competence. Conclusion: Study findings suggest that nurses' self-leadership is defined as having an important influence on nurses' clinical competence. In order to strengthen nurses' clinical competence, there is a need to develop education programs to increase nurses' self-leadership.