• 제목/요약/키워드: Clinical research trend

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Red ginseng monograph

  • So, Seung-Ho;Lee, Jong Won;Kim, Young-Sook;Hyun, Sun Hee;Han, Chang-Kyun
    • Journal of Ginseng Research
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    • v.42 no.4
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    • pp.549-561
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    • 2018
  • Ginseng has been traditionally used for several millennia in Asian countries, including Korea, China, and Japan, not only as a nourishing and tonifying agent but also as a therapeutic agent for a variety of diseases. In recent years, the various effects of red ginseng including immunity improvement, fatigue relief, memory improvement, blood circulation improvement, antioxidation, mitigation of menopausal women's symptoms, and anticancer an effect have been reported in clinical as well as basic research. Around the world, there is a trend of the rising consumption of health functional foods on the level of disease prevention along with increased interest in maintaining health because of population aging and the awareness of lifestyle diseases and chronic diseases. Red ginseng occupies an important position as a health functional food. But till now, international ginseng monographs including those of the World Health Organization have been based on data on white ginseng and have mentioned red ginseng only partly. Therefore, the red ginseng monograph is needed for component of red ginseng, functionality certified as a health functional food in the Korea Food and Drug Administration, major efficacy, action mechanism, and safety. The present red ginseng monograph will contribute to providing accurate information on red ginseng to agencies, businesses, and consumers both in South Korea and abroad.

Association between intake of antioxidant vitamins and metabolic syndrome risk among Korean adults (한국 성인의 항산화 비타민 섭취와 대사증후군 위험 간의 관련성)

  • Ahn, Seoeun;Jun, Shinyoung;Kang, Minji;Shin, Sangah;Wie, Gyung-Ah;Baik, Hyun Wook;Joung, Hyojee
    • Journal of Nutrition and Health
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    • v.50 no.4
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    • pp.313-324
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    • 2017
  • Purpose: The purpose of this study was to examine the association between intake of antioxidant vitamins and prevalence of metabolic syndrome (MetS) among Korean adults. Methods: A total of 614 subjects aged 30~60 years were recruited from those who received a medical checkup at a general hospital in South Korea between 2009 and 2012. Presence of MetS was determined based on criteria issued by the NCEP ATP III. Intakes of antioxidant vitamins (vitamin A, retinol, carotenoids, vitamin C, and vitamin E) were estimated by combining 3-day diet records with an antioxidant vitamin database for common Korean foods. We used multiple logistic regression analysis to assess the association between dietary intakes of antioxidant vitamins and MetS. Results: Men in the highest tertile for retinol (OR = 0.40, 95% CI = 0.23~0.71, P for trend = 0.0009), carotenoids (OR = 0.57, 95% CI = 0.32~1.00, P for trend = 0.0470), and vitamin E (OR = 0.52, 95% CI = 0.30~0.92, P for trend = 0.0190) intakes had a lower likelihood of having Mets than those in the lowest tertile. The OR of high fasting blood glucose among men in the highest tertile for vitamin A (${\mu}g$ RE: OR = 0.55, 95% CI = 0.32~0.97, P for trend = 0.0417, ${\mu}g$ RAE: OR = 0.52, 95% CI = 0.29~0.92, P for trend = 0.0211), carotenoids (OR = 0.41, 95% CI = 0.23~0.73, P for trend = 0.0036), and vitamin E (OR = 0.47, 95% CI = 0.26~0.82, P for trend = 0.0080) intakes was lower than those in the lowest tertile. In women, subjects in the highest tertile of retinol intakes had a lower prevalence of MetS than those in the lowest tertile group (OR = 0.55, 95% CI = 0.30~0.98). The OR for abdominal obesity was lower among women with the highest vitamin A (${\mu}g$ RE) intakes compared to those in the lowest tertile (OR = 0.51, 95% CI = 0.28~0.93, P for trend = 0.0293). Conclusion: These results suggest that dietary intakes of antioxidant vitamins might be associated with reduced risk of having MetS among Korean adults.

The Latest Research Trend on Chinese Medicine Treatment for Plantar Fasciitis Using China National Knowledge Infrastructure Database - Focused on Clinical Studies after 2018 (족저근막염의 중의학 치료에 대한 최신 임상 연구 동향: China National Knowledge Infrastructure 검색을 중심으로 - 2018년 이후 발표된 연구를 중심으로)

  • Na-Young Shin;Ah-Ra Koh;Young-Jin Lee;Jin-Woo Ahn;Hye-Jeong Jo;Go-Eun Chae;Hyn-Woo Kim;Hye-Jin Nam
    • Journal of Korean Medicine Rehabilitation
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    • v.33 no.2
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    • pp.33-48
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    • 2023
  • Objectives The purpose of this study is to investigate the latest research trends regarding the traditional Chinese medicine treatment of plantar fasciitis and suggest the direction for future research. Methods We investigated recent clinical studies about traditional Chines medicine treatment for Plantar fasciitis through searching the electronic database of China National Knowledge Infrastructure. We analyzed the characteristics of selected studies according to study design, criteria for diagnosis and evaluation, periods, treatment methods. Results Twenty-six clinical studies published from 2018 to 2022 were analyzed. Acupuncture, herbal medication, herbal fumigation and washing, herbal integration, herbal external application, and manual therapy were performed for the treatment of plantar fasciitis in China. In particular, studies on acupuncture, herbal fumigation and washing, and manual therapy were actively conducted and all of these treatment methods were effective. Conclusions Various Chinese medical interventions are being studied in China for the treatment of plantar fasciitis. However, in order to reinforce evidence for effectiveness of treatment, additional high-level clinical studies are required. It is considered that additional research related to the Korean medicine treatment for plantar fasciitis is needed in the future in Korea.

A Case Study on Math Clinical Counseling based on Connection with Class (수업과 연계한 수학 클리닉 상담 사례 연구)

  • Kim, Hong-Kyeom;Ko, Ho Kyoung
    • Communications of Mathematical Education
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    • v.32 no.2
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    • pp.113-129
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    • 2018
  • The importance of mathematics is increasing as human beings are entering the 4th industrial revolution era from the information society. In response to this trend, the government is also paying a lot of attention to math education by addressing 2012 mathematics education as 'the year of mathematics education.' However, many students are still suffering from mathematics and they feel math is difficult and even give up math. For this cause, students who give up math are showing up a lot in middle and high schools. For these math low achievers, the government, educational institutions, research institutes, and schools are creating and implementing a lot of programs. Among these programs, there is also a program called Math Clinic counseling. However, most of these math clinic counseling end up in a one-time events or are not linked to class because counselors and math teachers are different. So, this research focuses on this fact : gap between math clinical counseling and real mathematics class. The study analyze the reasons of the cause of low level of self-confidence in math and high level of math anxiety from the students. And it suggests some strategies for the individual students base on their difficulties. Applying these strategies to the students, the study mainly focused on how the strategies are presented in real class by observing practical classes.

A Study Trend for the Effects of Banxia-xiexin-tang Decoction (Banhasasim-tang) on Gastroesophageal Reflux Disease (GERD) in Chinese and Korean Databases over the Last Ten Years (중국 및 한국 Database에서의 위식도 역류질환에 대한 반하사심탕의 효과에 대한 최근 10년간의 연구경향)

  • Jung, Yu-jin;Kim, Yoon-jung;Hong, Sang-hoon
    • The Journal of Internal Korean Medicine
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    • v.41 no.3
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    • pp.362-413
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    • 2020
  • Objectives: The purpose of this research is to examine the recent clinical research trends on the efficiency of traditional herb medicine (THM) on gastroesophageal reflux disease (GERD), and to provide clinical evidence of herbal medicine, Banhasasin-tang or Banxiexin decoction by using a systemic review and meta-analysis of randomized trials (RCTs). Methods: In this study, randomized controlled trials (RCTs) were included that verified effects of traditional herbal medicine (THM), including a Banxia-xiexin-tang decoction, as a treatment for GERD. A study of the literature in Chinese and Korean databases was performed for papers published from January 1, 2010, to January 1, 2020. The selected literature was assessed by Cochrane's risk of bias (RoB). Results: A total of 90 RCTs met the inclusion criteria. Except for four RCT studies, all studies identified the effect of a Banxia-xiexin-tang decoction in the treatment of GERD. The effectiveness of treatment was significantly higher in the intervention group than in the control group, as shown through various evaluation indicators, including the reflux disease diagnostic questionnaire (RDQ). Adverse effects were reported in 22 articles (24.44%). Conclusions: Treatment with Banhasasin-tang, or a Banxia-xiexin-tang decoction, was found to be effective in treating GERD. However, due to the low quality of available studies, the significance of this conclusion is somewhat limited. This study could serve as a foundation for further clinical studies on the development of diagnosis and treatment methods for GERD based on Korean medicine.

Recent Domestic and International Trends in Clinical Research of Herbal Medicine Treatment for Crohn's disease (크론병의 한약 치료에 대한 최근 국내외 임상연구 동향)

  • Lee, Shin Hee;Heo, Yu Jin;Cho, Yun Soo
    • The Journal of Pediatrics of Korean Medicine
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    • v.35 no.4
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    • pp.56-74
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    • 2021
  • Objectives The purpose of this study is to analyze the trend of herbal medicine treatment, treatment's effect and stability for Crohn's disease by reviewing clinical studies published over the past 5 years. Methods 22 articles which were published from 2017 to August, 2021 were obtained from the ScienceON, Research information sharing service (RISS), Koreanstudies Information Service System (KISS), Oriental medicine advanced searching integrated system (OASIS), China national knowledge infrastructure (CNKI), Pubmed. We analyzed the literature in regards to the treatment methods and results. Results There were 6 case reports, 1 controlled clinical trial, and 15 randomized controlled trial and in most cases, herbal medicines and Western medicines were administered in combination. The pathology of damp-heat due to spleen deficiency was the most common, and Sijunzi-tang and Shenling Baishu san were the most commonly used. As a result of the treatment, it was found that the combined administration of the herbal medicine and the Western medicine was more effective than the administration of the Western medicine alone. Conclusions Herbal treatment of Crohn's disease induced high cure rate safely than when only western treatment was applied. Future studies on safety and studies that can suggest specific guidelines for the combined administration of western and herbal medicines are needed.

Research Trends in Using Korean Traditional Herbal Medicine for Dementia on the Improvement of Cognitive Function and Changes in Gut Microbiota (치매 한약치료의 인지기능 개선 및 장내 미생물 변화에 대한 연구동향)

  • Mi-Ra Choi;Jeong-Han Lee;So-Hyeon Park;Bo-Kyung Kim;Jung-Hwa Lim
    • Journal of Oriental Neuropsychiatry
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    • v.34 no.3
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    • pp.275-305
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    • 2023
  • Objectives: This study aimed to review clinical and experimental studies using Korean traditional herbal medicine for dementia on the improvement of cognitive function and changes in gut microbiota. Methods: We searched 12 databases for clinical and experimental studies on the effect of Korean traditional herbal medicine treatment for dementia on changes in gut microbiota. Sample sizes, dementia types, diagnosis criteria, interventions, outcomes, and results, including changes in gut microbiota, were extracted from the included clinical studies and analyzed. Subjects, interventions, outcomes, and results, including gut microbiota changes, were extracted from the included experimental studies and analyzed. Results: A total of 22 studies were selected, and most of them were experimental studies. Improvement in cognitive function and changes in gut microbiota were reported in all studies. The most frequently used herbal material was Poria cocos, and the most frequently used prescription was Danggwijagyak-san and Chilseong-hwan. Lactobacillus, Firmicutes, Bacteroidetes, and Proteobacteria were frequently assessed gut microbiota. Conclusions: These results suggest the treatment potential of Korean traditional herbal medicine for dementia by regulating gut microbiota. However, there were discrepancies related to changes in gut microbiota among studies. Therefore, further studies are needed to clarify the effect and mechanism of Korean traditional herbal medicine for dementia on gut microbiota.

Literatures Review in Hwabyung Research (홧병 연구에 관한 고찰)

  • Park, Young-Sook;Chae, Sun-Ok
    • Research in Community and Public Health Nursing
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    • v.12 no.3
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    • pp.705-715
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    • 2001
  • This study examined 19 papers published from 1977 to 2000 based on the objective frame evaluation. This purpose of this study was to examine the trend of Hwabyung research and to serve as a guide for the future 'Hwabyung' study. The results of studies were as follow. In the design of research, clinical studies are definitely dominant. As for the fields of research, the concept of Hwabyung was studied more frequently than the others. As for the authorship. psychiatrists prevailed but nursing professionals are on the increase. Research subject in clinical and survey study, patient was definitely dominant and the place of study was almost always a hospital (75%), data collection was higher on interview (58.3%). Hwabyung was considered unique culture bounded syndrome related to Korean culture. Frequent etiologic factor of Hwabyung were a husband's extra-marital affair, conflicts between houses wives and mothers-in-laws, and financial loss and suffering. From the incidence of Hwabyung, a greater number of patients with Hwabyung were middle aged women in the low economic and educational classes, and these were connected with the culture and the family system. The symptoms of Hwabyung included psychological and physical symptom, neurological disorder and disease behavior. Defense mechanisms and coping strategies for Hwabyung were somatization, suppression, orality, withdrawal, isolation, regression, help-seeking, complaining, and wreaking anger. Treatment of Hwabyung were medication, effort by herself, communication with families, consultation with psychologist, acupuncture, negative therapy, moxa, and Qi-kong. Psychiatric therapy, behavior therapy, nursing intervention on multi-interdisciplinary approach and psychiatric nursing approach were recommended for the nursing care of a Hwabyung patient.

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The Analysis of the Recent Research Trend of Traditional Korean Medicine Intervention with Woman Menopausal Symptoms (갱년기 여성 대상 한의약 중재요인의 국내 연구 동향분석)

  • Yun, Jung Min;Jang, Soobin;Kim, Kyeong Han
    • Journal of Society of Preventive Korean Medicine
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    • v.22 no.1
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    • pp.29-44
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    • 2018
  • Objectives : This study was conducted to survey on the research trends of Traditional Korean Medicine(TKM) intervention with woman menopausal symptoms in Korea. Method : We searched Korean research database by using keyword 'Menopause'. Korean research databases were Korean Studies Information Service System(KISS), Research Information Service System(RISS) and Korean Medicine Information System(OASIS). We classified articles identified by TKM treatments. Results : We analyzed 63 studies by classifying 4 interventions that consist of acupuncture treatment, herbal medicine, lifestyle modification, complex therapy. According to studies using acupuncture, Sameumgyo(三陰交, SP6) was the most treated. Soyosan(逍遙散) was most treated in herbal medicine studies, and massage was most used in lifestyle modification. Conclusion : A variety of treatment using TKM have been used for menopausal women. It is necessary to increase the level of evidence of TKM intervention through additional studies in the future.

A Review of Domestic Research Trends Related to the International Classification of Functioning, Disability and Health (ICF): 2015-2020

  • Song, Ju-Min
    • Journal of the Korean Society of Physical Medicine
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    • v.16 no.3
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    • pp.65-80
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    • 2021
  • PURPOSE: This study was conducted as a literature review to analyze the research trends related to the International Classification of Functioning, Disability and Health (ICF) in Korea from 2015 to 2020. METHODS: Precedent studies were searched with the search term "ICF" or "international classification of functioning, disability and health" from the databases of RISS, KISS, DBpia, and Pubmed. The inclusion criteria are that the studies have been carried out in Korea from 2015 to 2020 using ICF by researchers consisting of one or more Koreans and have been peer-reviewed. RESULTS: Of the total 269 studies, 107 that met the inclusion criteria were analyzed. It was found that these studies were published at a similar frequency each year. The most common area of expertise was identified as the clinical area (n = 67), followed by special education (n = 21) and social welfare (n = 13). The study subject groups were mostly patients (n = 39), disabled people (n = 25), and related experts (n = 13). The most common research topic was functioning evaluation (n = 49) and followed by a literature review (n = 29), and the most frequently used components in all the areas of expertise were activity and participation (n = 98), body function and structure (n = 73), and environmental factors (n = 61). CONCLUSION: For the past six years, domestic ICF-related research has been conducted in a wider range of expertise areas on more subdivised subject groups. Continuous research, development of standardized curricula and contents, and development of coding tools are considered to be important in vitalizing the use of the ICF.