• Annals of Clinical Neurophysiology
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• 제26권1호
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• pp.30-33
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• 2024

Rippling muscle disease (RMD) is caused by dominant mutations of the caveolin-3 gene (CAV3), and presents with overlapping limb-girdle muscle weakness, elevated creatine kinase (hyper-CKemia), RMD, and distal myopathy. We report a patient with a CAV3 mutation who presented with myalgia, exercise-induced muscle stiffness, hyperCKemia, and percussion-induced rapid muscle contraction and muscle mounding. A familial genetic study revealed the same mutation in two family members, with physical examinations showing that both of them had rippling muscles.

• Annals of Clinical Neurophysiology
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• 제10권2호
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• pp.109-111
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• 2008

Ossification of the ligamentum flavum (OLF) usually occurs in the lower thoracic spine, and is rare in the cervical region. We report the case of a 67-year-old woman who presented a seven month's history of progressive weakness and paresthesia in her right upper extremity. MRI and CT scans of the spine revealed the presence of ossified ligamentum flavum from C3-C4. A cervical laminectomy resulted in a good post-operative improvement of muscle strength.

• Annals of Clinical Neurophysiology
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• 제14권1호
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• pp.41-44
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• 2012

Thenar motor neuropathy (TMN) is a compressive mononeuropathy of recurrent motor branch of median nerve. It is infrequent and may have different pathogenesis. It may be a unique entity of disease or considered a variant of carpal tunnel syndrome involving the motor branch only. We report a case of TMN induced by vigorous massage that applied strong digital pressure in the region of the base of palm and thenar muscles.

• Annals of Clinical Neurophysiology
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• 제6권1호
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• pp.39-42
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• 2004

A 20-year-old man with bilateral medial medullary infarction showed transition of bowtie and upbeat nystagmus into hemi-seesaw nystagmus. Follow-up MRI revealed near complete resolution of the right medullary lesion. This transition of nystagmus suggests that the upbeat nystagmus was generated by bilateral lesions in the ascending pathways from both anterior semicircular canals (SCC), and that the hemi-seesaw nystagmus was caused by damage to the pathway from the left anterior SCC.

• Annals of Clinical Neurophysiology
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• 제10권1호
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• pp.48-51
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• 2008

Since the majority of cases with unilateral peripheral facial palsy are idiopathic, radiological studies such as CT or MRI are not usually recommended for further evaluation. We report a patient with peripheral facial palsy caused by minor salivary gland tumor which was demonstrated by appropriate imaging study.

• Annals of Clinical Neurophysiology
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• 제4권1호
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• pp.81-84
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• 2002

Tetanus is a disorder known to interfere with inhibitory modulation of the motor system in humans. In this report, we describe the characteristic neurophysiological findings in a 52-year-old patient with generalized tetanus. The cutaneous silent period was absent and the silent period evoked in distal upper limb muscles by transcranial magnetic stimulation was shortened. These findings can be interpreted as evidence of impaired inhibitory mechanisms at multiple levels of the nervous system.

• Annals of Clinical Neurophysiology
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• 제7권2호
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• pp.141-142
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• 2005

Two cases of bilateral ulnar neuropathies caused by telephone overuse are described in people engaged in the job of longtime telephone use. They had worked using telephone all through the working hours. Although they were right handed, they usually used the telephone in their left hand so as to leave their right hand free for writing, and would lean his elbow on the desk. Telesales or teleconsultation is a rapidly expanding field of business. These cases highlights the need of proper training and supplies appropriate to do their job.

• Annals of Clinical Neurophysiology
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• 제8권2호
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• pp.199-202
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• 2006

We report a case of chiasmal optic neuritis in a patient who had been diagnosed as multiple sclerosis, and was presented with bitemporal hemianopsia. The brain MRI revealed a high signal lesion with focal enhancement in optic chiasm, and the visual evoked potential functionally supported it. This is the first case of chiasmal optic neuritis in multiple sclerosis with temporally and spatially disseminated lesions.

• Annals of Clinical Neurophysiology
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• 제8권2호
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• pp.182-185
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• 2006

Various immunotherapeutic modalities have been used based on the autoimmune pathogenic mechanisms of myasthenia gravis (MG). Cell-mediated immunity as well as auto-antibodies may play a role in the remission and relapse of MG. We recently experienced two patients with MG who showed spontaneous remission after inadvertent severe leukopenia. These findings suggest that the cell-mediated immune process is important in the treatment of MG, and selective suppression of leukocyte may induce remission in the patients with intractable MG.

• Annals of Clinical Neurophysiology
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• 제22권1호
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• pp.41-45
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• 2020

Acute sarcoid myositis is rarely complicated by sarcoidosis, and steroid therapy is considered the standard treatment. We experienced a patient with acute sarcoid myositis who did not respond to aggressive high-dose corticosteroid therapy, but showed a dramatic improvement after the addition of weekly low-dose oral methotrexate (MTX). This intervention allowed the resumption of normal daily activities after 6 months. Our case strongly suggests that MTX should be considered in patients with acute sarcoid myositis that is resistant to corticosteroid therapy.