Transient Remission of Myasthenia Gravis Following Leukopenia

백혈구감소증 후에 일과성으로 관해된 중증근무력증

  • Go, Seok Min (Department of Neurology Seoul Medical Center) ;
  • Bae, Jong Seok (Department of Neurology Seoul Medical Center) ;
  • Ahn, Jin Young (Department of Neurology Seoul Medical Center) ;
  • Kim, Min Ky (Department of Neurology Seoul Medical Center) ;
  • Kim, Byoung Joon (Department of Neurology Samsung Medical Center Sungkyunkwan University School of Medicine)
  • 고석민 (서울의료원 신경과) ;
  • 배종석 (서울의료원 신경과) ;
  • 안진영 (서울의료원 신경과) ;
  • 김민기 (서울의료원 신경과) ;
  • 김병준 (성균관대학교 의과대학 삼성서울병원 신경과)
  • Published : 2006.12.30

Abstract

Various immunotherapeutic modalities have been used based on the autoimmune pathogenic mechanisms of myasthenia gravis (MG). Cell-mediated immunity as well as auto-antibodies may play a role in the remission and relapse of MG. We recently experienced two patients with MG who showed spontaneous remission after inadvertent severe leukopenia. These findings suggest that the cell-mediated immune process is important in the treatment of MG, and selective suppression of leukocyte may induce remission in the patients with intractable MG.

Keywords