• Title/Summary/Keyword: Clinical adaptation

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Cerebellar Control of Saccades (소뇌의 단속안구운동 조절)

  • Choi, Jae-Hwan;Choi, Kwang-Dong
    • Annals of Clinical Neurophysiology
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    • v.15 no.2
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    • pp.37-41
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    • 2013
  • Saccades are rapid eye movements that shift the line of sight between successive points of fixation. The cerebellum calibrates saccadic amplitude (dorsal vermis and fastigial nucleus) and the saccadic pulse-step match (flocculus) for optimal visuo-ocular motor behavior. Based on electrophysiology and the pharmacological inactivation studies, early activity in one fastigial nucleus could be important for accelerating the eyes at the beginning of a saccade, and the later activity in the other fastigial nucleus could be critical for stopping the eye on target, which is controlled by inhibitory projection from the dorsal vermis. The cerebellum could monitor a corollary discharge of the saccadic command and terminate the eye movement when it is calculated to be on target. The fastigial nucleus and dorsal vermis also participate in the adaptive control of saccadic accuracy.

Analysis of Factors Affecting Stress in the Elderly Women

  • Kang, Yun-Jung;Lee, Gil-Hyun
    • Biomedical Science Letters
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    • v.24 no.4
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    • pp.319-328
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    • 2018
  • The purpose of this study is to identify the factors influencing the stress of the elderly women by various tools and to provide basic data for adaptation to the aging women. For this purpose, stress was measured by stress measuring equipment (HRV) and stress measurement questionnaire (SRI) in 31 elderly women over 60 years old. In summary, the results of this study suggest that the worse the subjective health, and when there is a spouse, it predicts a stress. In order to reduce the stress of elderly women based on these results, physical health management and environmental factors that can enhance the intimacy between husband and wife are also necessary.

Novel pan-lineage VP1 specific degenerate primers for precise genetic characterization of serotype O foot and mouth disease virus circulating in India

  • Sagar Ashok Khulape;Jitendra Kumar Biswal;Chandrakanta Jana;Saravanan Subramaniam;Rabindra Prasad Singh
    • Journal of Veterinary Science
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    • v.24 no.3
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    • pp.40.1-40.6
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    • 2023
  • Analysis of the VP1 gene sequence of the foot and mouth disease virus (FMDV) is critical to understanding viral evolution and disease epidemiology. A standard set of primers have been used for the detection and sequence analysis of the VP1 gene of FMDV directly from suspected clinical samples with limited success. The study validated VP1-specific degenerate primer-based reverse transcription polymerase chain reaction (RT-PCR) for the qualitative detection and sequencing of serotype O FMDV lineages circulating in India. The novel degenerate primer-based RT-PCR amplifying the VP1 gene can circumvent the genetic heterogeneity observed in viruses after cell culture adaptation and facilitate precise viral gene sequence analysis from clinical samples.

A Study on the Stress, Self-Esteem, Mental-Health and Suicidal-Ideation in Nursing Students (간호대학생의 스트레스, 자아존중감, 정신건강 및 자살생각에 관한 연구)

  • Jung, Ha-Yun;Lee, Kyung-Soo
    • Journal of Korean Clinical Health Science
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    • v.3 no.2
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    • pp.328-339
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    • 2015
  • Purpose. This study was to intended to identify relationship between stress, self-esteem, mental health and suicidal ideation in nursing students. Methods. Participants were 338 nursing students who studied in 2 nursing colleges in Gyeongsangnam-do. The period of data collection was from November 1 to 10, 2014. The data ware analyzed by Frequencies, t-test, one way ANOVA, Pearson's correlation coefficients and Stepwise multiple regression using the SPSS 20.0 program. Results. The results are as followed : First, the average of stress, self-esteem, mental health, and suicidal-ideation was $2.60{\pm}0.57$, $3.64{\pm}0.44$, $2.18{\pm}0.38$, and $1.46{\pm}0.37$ points. Second, suicidal ideation was significantly different according to personality, adaption of environment, health status, satisfaction on nursing major, and satisfaction on school life. Third, suicidal ideation was correlated with mental health positively and self-esteem negatively. Forth, the influencing factor in suicidal ideation of participants was mental health, self-esteem, and adaptation of environment, $R^2=.669$. Conclusions. Development and application of counseling and regular education program to decrease stress, suicidal ideation and raise self-esteem, mental-health, and adaptation of environment are required, practical education program should to conducted and studies showing its results and effect are also needed.

The Effects of Muscle Contraction by Electrical Stimulation to V Wave and Median Frequency (전기자극에 의한 근 수축이 V wave와 중앙주파수에 미치는 영향)

  • Mun, Dal-Ju;Jeong, Dae-In;Lee, Jung-Woo;Jeong, Jin-Gyu;Kim, Tae-Youl;Oh, Myung-Hwa
    • Journal of the Korean Academy of Clinical Electrophysiology
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    • v.4 no.1
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    • pp.27-38
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    • 2006
  • This study analyzed changes in action potential of supraspinal neuron and motor unit depending on maximum tolerance isometric contraction(MTIC) by electrical stimulation and examined influence of functional electrical stimulation (FES) on spinal neuron adaptation. It selected 40 university students in their twenties and divided into experimental groups of 25% MTIC(I), 50% MTIC I (II), 75% MTIC(III) and 100% MTIC(IV) depending on MTIC by electrical stimulation, and performed isometric contraction of plantar flexor muscle to each experimental group with given contraction for 20 times. It measured V/Mmax and MDF pre and post exercise, compared volume of contraction. 1. V/Mmax ratio showed no significant difference in comparison among experimental groups. 2. There was significant difference in median frequency of gastrocnemius and soleus in action potential motor unit according to comparison among experimental groups(p<.001). When contraction by electrical stimulation was maximum, change was greatest. This results suggest that muscle contraction by electrical stimulation was influence to action potential of spinal motor neuron system which appear optimal level though aspect and difference degree were not in accordance. Consequently, optimal stimulation level of MTIC(50%) by FES would be lead to central nerve adaptation. muscle contraction by electrical stimulation was influence highly to MDF which should be consider to fatigue of motor unit for muscle contraction by electrical stimulation.

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Translation and Content Validity of the Korean Version of the Motor Activity Log (한국어판 운동활동일지(Korean Version-Motor Activity Log) 번안과 내용타당도 연구)

  • Kim, Sujin;Hwang, Sujin
    • PNF and Movement
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    • v.20 no.2
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    • pp.263-273
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    • 2022
  • Purpose: Translation and adaptation involve cross-cultural and conceptual aspects; they are not simply based on linguistic equivalence. This study aimed to produce a conceptually equivalent Korean version of the motor activity log (K-MAL) for the upper extremities that can be applied across the Korean population and its cultures. Methods: Following the procedures used in the translation of other cross-cultural evaluation tools, and the five steps of the translation process, the motor activity log (MAL) was translated into Korean (K-MAL). We then examined the content validity of the K-MAL. Twenty-two rehabilitation professionals (11 males and 11 females, mean length of clinical career = 101.54 months) assessed the content validity of the K-MAL. The content validity ratio and content validity index were used to verify the content validity. Results: There were inconsistencies found in three sub-items in the MAL during the forward translation process. These inconsistencies were corrected, and the complete K-MAL was produced. The exact critical values of the content validity ratio and the content validity index of the K-MAL were 0.45-0.95 and 0.77-1.00, respectively. Conclusion: The K-MAL was successfully developed using a systematic methodology, which included translation, adaptation, and evaluation of the content validity. We expect that stroke rehabilitation professionals working in both clinical and research settings will apply the K-MAL when evaluating the amount and quality of use of the upper extremities in post-stroke patients in Korea.

Epigallocatechin-3-gallate prior to composite resin in abfraction lesions: a split-mouth randomized clinical trial

  • Luisa Valente Gotardo Lara Alves;Lisiane Martins Fracasso;Thiago Vinicius Cortez;Aline Evangelista Souza-Gabriel;Silmara Aparecida Milori Corona
    • Restorative Dentistry and Endodontics
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    • v.48 no.2
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    • pp.13.1-13.11
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    • 2023
  • Objectives: Natural extracts have been investigated as a biomimetic strategy to mechanically strengthen the collagen network and control the biodegradation of extracellular matrix. This study evaluated the effect of epigallocatechin-3-gallate (EGCG) on abfraction lesions prior to the composite resin. Materials and Methods: The sample consisted of 30 patients (aged between 28 and 60 years) with abfraction lesions located in 2 homologous premolars. The teeth were randomly assigned according to dentin treatment: 0.02% EGCG solution or distilled water (control). After enamel acid etching, the solutions were applied immediately for 1 minute. The teeth were restored with Universal Adhesive (3M) and Filtek Z350 XT (3M). Analyzes were done by 2 independent examiners using modified USPHS (retention, secondary caries, marginal adaptation, and postoperative sensitivity) and photographic (color, marginal pigmentation, and anatomical form) criteria at baseline (7 days) and final (18 months). The data analysis used Friedman and Wilcoxon signed-rank tests (α = 0.05). Results: At baseline, all restorations were evaluated as alpha for all criteria. After 18 months, restorations were evaluated as alpha for secondary caries, color, and marginal pigmentation. There was significant difference between baseline and 18 months (p = 0.009) for marginal adaptation and postoperative sensitivity (p = 0.029), but no significant difference were verified between treatments (p = 0.433). The EGCG group had a restoration retention rate of 93.3%, while the control group had 96.7%. Conclusions: The application of EGCG solution on abfraction lesions did not significantly influence the survival of the restorations based on clinical and photographic criteria.

Analysis of the Knowledge Structure of Research related to Reality Shock Experienced by New Graduate Nurses using Text Network Analysis (텍스트네트워크분석을 활용한 신규간호사가 경험하는 현실충격 관련 연구의 지식구조 분석)

  • Heejang Yun
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.1
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    • pp.463-469
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    • 2023
  • The aim of this study is to provide basic data that can contribute to improving successful clinical adaptation and reducing turnover of new graduate nurses by analyzing research related to reality shock experienced by new graduate nurses using text network analysis. The topics of reality shock experienced by new graduate nurses were extracted from 115 papers published in domestic and foreign journals from January 2002 to December 2021. Articles were retrieved from 6 databases (Korean DB: DBpia, KISS, RISS /International DB: Web of science, Springer, Scopus). Keywords were extracted from the abstract and organized using semantic morphemes. Network analysis and topic modeling for subject knowledge structure analysis were performed using NetMiner 4.5.0 program. The core keywords included 'new graduate nurses', 'reality shock', 'transition', 'student nurse', 'experience', 'practice', 'work environment', 'role', 'care' and 'education'. In recent articles on reality shock experienced by new graduate nurses, three major topics were extracted by LDA (Latent Dirichlet Allocation) techniques: 'turnover', 'work environment', 'experience of transition'. Based on this research, the necessity of interventional research that can effectively reduce the reality shock experienced by new graduate nurses and successfully help clinical adaptation is suggested.

Translation and Content Validation of the Korean Version of the Falls Efficacy Scale for Stroke and Brain Injury Patients (뇌졸중 및 뇌손상 환자를 위한 한국판 넘어짐효능감척도(Korean Version-Falls Efficacy Scale) 번안과 내용타당도 연구)

  • Su-jin Kim;Jeong-Ah Kim;Su-jin Hwang
    • PNF and Movement
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    • v.21 no.3
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    • pp.387-401
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    • 2023
  • Purpose: The purpose of this study was to develop a Korean version of the Falls Efficacy Scale (K-FES), which is used to measure the fear of falling, that is conceptually equivalent to the original and culturally adaptable to the Korean population. Methods: A five-step translation and adaptation process was employed to create the K-FES, adhering to the established guidelines for cross-cultural rehabilitation outcome measures. The content validity was then evaluated by 22 rehabilitation professionals (15 males and 7 females) with an average clinical experience of 201 months at neurological rehabilitation centers. The content validity ratio and index were used as a basis for judgment. Results: The translation process identified inconsistencies with the terms "objects" and "telephone" in the original Falls Efficacy Scale, which were subsequently resolved in the final K-FES version. The content validity ratios for the original, second, and third versions of the K-FES ranged from -0.27-0.91, -0.27-0.91, and -0.27-0.91, respectively. Correspondingly, the content validity index values for the original, second, and third versions of the K-FES ranged from 0.77-1.00, 0.68-1.00, and 0.63-1.00, respectively. Conclusions: The K-FES was rigorously developed through translation, adaptation, and validation processes, making it a reliable tool for Korean stroke rehabilitation professionals. It is expected to be instrumental in clinical and research settings to assess postural stability and fall risk in patients with strokes and brain injuries.

Effects of Family Violence during Childhood on Early Adulthood Adaptation. - Focusing on 'experienced violence' and 'observed violence' - (성장기 가정 내 폭력 경험이 성인 초기 적응에 미치는 영향 - 부모간의 폭력 관찰 경험과 자신에 대한 폭력 행동 경험을 중심으로 -)

  • Gwi-Yeo-Roo Ahn;Kyung-Hyun Suh
    • Korean Journal of Culture and Social Issue
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    • v.13 no.4
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    • pp.83-100
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    • 2007
  • It is the aim of present paper to examine the effects of experienced violence and observed violence in original family on adaptation in college students. In addition, the degree of contribution of two types of aggression in family were examined. Participants were 220 college students. Among them, those who have experienced violence from mother are 60.3%. And 52.3% reported violence from father. Those who have observed their parents violent behavior are 28.8%. These childhood 'experienced violence' and 'observed violence' was significantly associated early adulthood adaptation. But its effect is dependent on participant's sex. Experienced violence from mother is positively related to confidence in scholastic achievement in female. Experienced violence from father is positively related to trumatic symptoms and trait anxiety in male. On the other hand, observed violence showed significant relationship with traumatic symptoms, impulsivity, depression, self-esteem and trait anxiety. Most importantly, multiple regression analysis showed observed violence explains early adulthood adaptation more significantly than experienced violence. The discussion addressed implications of the findings for future research and for clinical practice.

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