• Title/Summary/Keyword: Clinical Studies

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Recent Research Trends in Korean Medicine Treatment of Diabetes Mellitus - Focusing on Domestic Articles from 2008 to 2013 - (당뇨병의 한의학적 치료에 대한 최신 연구 동향 - 2008년부터 2013년까지 국내 학술논문을 중심으로 -)

  • Kim, Do-Hyung;Park, Seung-Chan;Lee, Ji-Hye;Lee, Hye-Yoon;Cho, Min-Kyoung;Choi, Jun-Yong;Kim, So-Yeon;Park, Seong-Ha
    • The Journal of Internal Korean Medicine
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    • v.34 no.3
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    • pp.240-255
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    • 2013
  • Objectives : This study was performed to research trends in Korean medicine treatment of diabetes mellitus (DM). Methods : We reviewed 73 studies about diabetes mellitus, which had been published from 2008 to 2013. The article search was performed on the Korean institute of oriental medicine (KIOM) database. Results : 1. Patterns of study design were as follows : 14 review studies, 44 experimental studies, 7 clinical studies, 8 case reports. 2. From the 14 review studies, we noted that literature studies about definition, pathologic mechanism, treatment, pathologic pattern identification of DM and previous study analyses were done. 3. From the 44 experimental studies that are the most common type of DM studies, various Korean medicine treatments such as single medicinal herbs, herbal complexes, diets and pharmacopuncture were used. Anti-diabetic effects were demonstrated in most of the studies. 4. 7 clinical studies about acupuncture, electroacupuncture, herbal medicine, etc. were reported. 5. 8 cases about DM complications and comorbidities were reported. Clinical symptoms improved in all of studies, blood sugar level decreased in four studies. Conclusions : Further clinical and case study based on experimental researches should be performed.

Adverse Events of Thread Embedding Acupuncture for the Musculoskeletal Conditions and Diseases: A Narrative Review of Clinical Studies

  • Lee, Ji Sun;Oh, Yoona;Kim, Yeonhak;Lee, Byung Ryul;Yang, Gi Young;Kim, Eunseok
    • Journal of Acupuncture Research
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    • v.39 no.1
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    • pp.10-16
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    • 2022
  • This study aimed to analyze the status of adverse events (AEs) in the treatment of musculoskeletal conditions/diseases using thread embedding acupuncture (TEA). Five electronic databases were searched to retrieve data on clinical studies published in the last 5 years (2016 to 2021). Of the 151 studies retrieved, 22 studies analyzed AEs and were selected for this review. There were no AEs reported in 6 studies (27.3%); of the remaining 16 studies, 4 studies (18.2%) reported AEs that were not related to TEA. The most common AEs reported in the Chinese studies were redness of skin with/without swelling and tingling sensation, and in the Korean studies they were stiffness, a foreign body sensation, and bruising. The percentage of patients with AE experience was 5.1% in the Chinese studies and 19.9% in the Korean studies. The discrepancies between the findings in the Chinese and Korean studies may be attribute to differences in the diameter of needles, thread materials, TEA treatment procedure, and evaluation methods for AEs. Most of the reported AEs were of a mild status and did not last for a long time. However, further research on the clinical course after TEA treatment is needed.

The Systematic Review of Clincal Trial(s) Intervening Traditional Korean Herbal Medicine: Extension of Developing Clinical Guideline for Hwa-byung (화병 진료지침 개발을 위한 한약 임상시험 방법론 연구)

  • Kim, Seok-Hwan;Park, Bo-Ra;Choi, Keum-Ae;Lim, Hyun-Ju;Lee, Sang-Ryong;Jung, Dae-Gyu;Kim, Rak-Hyung;Kim, Tae-Hun;Kim, Kyung-Ok;Jung, In-Chul
    • Journal of Oriental Neuropsychiatry
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    • v.20 no.2
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    • pp.163-176
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    • 2009
  • Objectives : To address most probable and suitable method for designing clinical trial intervening Traditional Korean Herbal Medicine on hwa-byung. Study Design : A systematic review of research studies of complementary and/or alternative medical(CAM) treatment of depression, and of domestic clinical trials of Traditional Korean Medicine, and of Chinese clinical trials of Traditional Chinese Medicine. Methods : Randomized, controlled trials(RCTs) of treatment of depression intervening herbal medicine were searched through MEDLINE, Cochrane Library, and CNKI databases. Also, domestic RCTs intervening Traditional Korean Herbal Medicine were searched through Korean Traditional Knowledge Portal and Korean studies Information Service System(KISS). Studies were evaluated using Iadad scale and self-designed tool for this study. Results : Thirty four RCT studies( 10 from MEDLINE, 16 from CNKI, 8 domestic studies) of herbal medicine met inclusion criteria. Mean Jadad score of studies published in English was 2.8${\pm}$0.79, in Chinese 1.94${\pm}$0.77, and in Korean 2.75${\pm}$0.71. Twenty one percent of studies included pattern differentiation in their inclusion criteria. Twenty nine percent of studies used combined treatment of herbal and conventional medicine. Among studies on depression, 9% included Complementary Medical assessing tools. Conclusions : There is shortage of domestic clinical trial involving herbal medicine. In China, studies tend to focus on investigating effect of Combined treatment of herbal and conventional medicine on depression. Clinical trial(s) of hwa-byung should provide good internal validity by describing methodology for randomization, double-blinding, and attrition. Also, specific guideline for clinical trial, including Traditional Korean Medical aspects across inclusion criteria, and assessing tools is needed.

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A Study on the Development of Clinical Workstation (임상용 워크스테이션의 개발에 관한 연구)

  • Park, Kwang-Seok;Lee, Tae-Su;Min, Byeong-Gu
    • Journal of Biomedical Engineering Research
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    • v.11 no.1
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    • pp.141-146
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    • 1990
  • A clinical workstation has been developed for the use in clinical ward. This system is connected to the Picture Archiving and Communication System previously installed. It provides the capabilities of image display, image processing, diagnostic report review, clinical lab data review and analytic diagrams presentation for the hospitalized patients in clinical ward. The performances of this system were evaluated during the 9 months. These results show typical aspects of clinical patterns in data transmissions, image studies and clinical lab data studies. These typical aspects should be counted in the further development of workstation for the clinical use.

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The Characteristics of KM Clinical Trials - Focusing on the Clinical Research Information Service (CRIS) (한약 임상시험의 특성 : 질병관리본부 임상연구정보서비스(CRIS)를 중심으로)

  • Jeung, Chang-woon;Jeon, Sun-woo;Jo, Hee-Geun
    • The Journal of Internal Korean Medicine
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    • v.41 no.6
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    • pp.959-966
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    • 2020
  • Objectives: To examine the fundamental characteristics of interventional clinical trials registered in the CRIS (Clinical Research Information Service) database. Methods: We systematically analyzed the status of Korean medical interventions using the search function of the CRIS database. Results: From 2010 to January 2020, 267 Korean medicine-related clinical trials were registered with CRIS. The studies, which included many randomized trials (80.14%), focused primarily on demonstrating the effectiveness and safety of acupuncture and Korean herbal remedies. Most of these studies were government-sponsored and researcher-led clinical trials, but a few were company-sponsored trials. All trials were small and need improvement. Conclusion: This study reviews the current status of clinical trials in the field of Korean medicine and the basic data that can be used to create evidence-based Korean medicine.

A Review of Research on Electroacupuncture for Female Stress Urinary Incontinence (여성 복압성 요실금에 대한 전침치료 연구 동향)

  • Park, Eo-Jin;Jo, Hyun-Jeong;Jo, Hee-Guen
    • The Journal of Korean Obstetrics and Gynecology
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    • v.30 no.4
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    • pp.149-174
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    • 2017
  • Objectives: The aim of this study is to establish a base for further research by reviewing studies on electroacupuncture (EA) for stress urinary incontinence (SUI). Methods: Clinical studies concerning the effects of EA for SUI, were obtained from Cochrane Library, PubMed, CNKI, RISS, NDSL, KISS and OASIS. Results: Forty-five studies met the criteria, which included 33 RCTs, 1 pilot RCT, 4 non-randomized Clinical Trials, 6 Case studies and 1 Orthogonal design study with 3638 patients. There was only one article published in Korea. In these study, the most common primary outcome measurement was the pad test. Most of the studies showed the group treated by EA effects compared to the control group. Also, many interventions that combined with EA were found and all complex therapy group had significantly better than control group. 7 studies observed adverse events (AEs), four of which referred to EA related AEs among them. And 4 studies reported no AEs associated with EA. Conclusions: Despite several limitations, various studies to prove limited yet effective EA on SUI provides much significance. Subsequent studies conducted by the complementary systematic review of the studies and well-designed clinical trials using the methodological quality will be needed to more firmly validate the therapeutic effect of EA on SUI.

A Review of Recent Korean Medicine Treatment for Chronic Subdural Hematoma Using the CNKI Database (만성 경막하 혈종(Chronic Subdural Hematoma)의 한의 치료에 대한 최신 임상연구 동향 - CNKI 검색을 중심으로 -)

  • Je, Yu-ran;Kim, Kyong-lim;Hwang, Won-deok
    • The Journal of Internal Korean Medicine
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    • v.42 no.3
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    • pp.308-322
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    • 2021
  • Objectives: This study investigates the latest clinical studies on Korean medicine treatment of chronic subdural hematoma (CSDH) in China. Methods: A CNKI search investigated the last 10 years of clinical studies of Korean medicine treatments in Chinese medical journals for CSDH. The search focused on authors, publication years, types of studies, purposes of studies, methods and duration of treatment, evaluation criteria, and results of treatment. Results: In 19 studies, there were 14 randomized controlled trials (RCTs), 4 case series, and 1 case-control study. In all 19 studies, Korean medical treatment and Western treatment were combined. Herbal medicine was used in 19 studies and acupuncture treatment in 2 studies. The most frequently used prescription was Hyeolbuchukeo-tang-gagambang, and the most frequently used acupoint was PC6. In all 19 studies, the effectiveness of Korean medicine treatment performed in parallel with Western treatment was confirmed. Conclusions: In this study, Korean medicine combined with Western treatment for CSDH was effective. More clinical studies and case reports are required to develop a guided treatment for CSDH.

Trends of Clinical Research on Facial Spasm in Korean Medicine: A Review of Case Studies

  • Hea Sun Chun;Ju Chul Kim
    • Journal of Acupuncture Research
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    • v.40 no.2
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    • pp.97-110
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    • 2023
  • This review aimed to examine and analyze trends of clinical research using case studies on facial spasms in Korean medicine. Seven web databases were searched for case studies on facial spasms using Korean and English search terms. Case studies were selected using the exclusion and inclusion criteria. Overall, 13 case studies were selected, analyzed, and classified according to the publication year and journal, study participants, cause, treatment methods, pattern identification, evaluation methods, improvement, and side effects. Case studies reporting on various treatment methods in Korean medicine, including acupuncture and pharmacopuncture for facial spasms, have been published since 2000. In addition, studies on new treatment methods in Korean medicine for facial spasm have been published. Combination therapy is the most common method used in Korean medicine-based case studies; therefore, future studies on single treatment are necessary. Most of the case studies on Korean medicine reported improved symptoms and patient satisfaction with the Korean medicine treatment method. No side effects were reported, except for facial swelling and bruising, indicating that Korean medicine treatment methods for facial spasm were safe and effective. Therefore, the Korean medicine treatment methods for facial spasm can be actively used in clinical practice and future research.

Analysis of Students Experience related of Nursing Management Clinical Practice: Text Network Analysis Method (Text Network Analysis를 이용한 간호관리학 실습경험 분석)

  • Kang, Kyeong Hwa;Yu, Soyoung
    • Journal of Korean Academy of Nursing Administration
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    • v.22 no.1
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    • pp.80-90
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    • 2016
  • Purpose: The purpose of this study was to analyze students experiences during clinical practice in nursing management. Methods: Assessing through computerized databases, self-reflection reports of 57 students were analyzed. Text network analysis was applied to examine the research. The keywords from each student's reports were extracted by using the programs, KrKwic and NetMiner. Results: The results of the keyword network analysis of what students learned in the nursing process included 27 words. The keyword network analysis of what students learned from the problem solving process included 23 words and the keyword network analysis of improvements in Clinical Practice of Nursing included 31 words. Conclusion: Studies related to clinical practice have been increasing, and themes of the studies have also become broader. Further research is required to investigate factors affecting clinical practice specifically in nursing management. Further comparative studies are necessary to define differences in clinical practice systems related to improving nursing students competency.

The Review on the Randomized Controlled Clinical Trials of Bee Venom in the Journal of Korean Medicine (봉독을 이용한 무작위배정 임상연구의 국내 현황)

  • Lee, Yong-Seok;Lee, Young-Joon;Han, Chang-Hyun
    • Journal of Korean Medicine Rehabilitation
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    • v.23 no.3
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    • pp.87-106
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    • 2013
  • Objectives We will provide basic information on bee venom clinical tests and aid the practical use of bee venom in such tests, through examination of RCT research related to bee venom that was reported domestically. Methods We collected 365 articles on Bee venom study result from the OASIS system using the Keyword 'bee venom, apitoxin, apitherapy, bee sting'. The initially selected theses were primarily screened for clinical research. Out of these, case studies and non randomized controlled trial (non-RCT) were ruled out. As a result, 39 studies of randomized controlled trial (RCT) research were chosen as the subjects of study. Results RCT research related to bee venom was first presented in 2003, and 39 studies have been published until 2012. 18 studies were tests to confirm the effectiveness of bee venom, 7 studies were comparisons between SBV and BV, and 13 studies were comparisons with other types of treatment. Research conducted through appropriate randomization methods were 20 studies, and inappropriate randomization methods were used in 19 studies. In therms of Jadad score, 12 studies received 4~5 points, 15 studies received 1-3 points, and 12 studies received zero point. Conclusions In order to assure good quality RCT research, appropriate guidelines should be provided, and proper evaluation standards should be established. In-depth study is needed concerning the difference of responses to treatment according to the types of treatment received. A standardization of treatment should be reached as a result.