• Title/Summary/Keyword: Clinical Research Information Service

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Clinical research methodology for Traditional Korean Medicine treatment of lung cancer : Evidence-based approach (폐암(肺癌)의 한방치료 임상연구 방법론)

  • Kim, Kyung-Suk;Kim, Sme-Hyun;Eo, Wan-Kyu;Cheon, Seong-Ha;Eom, Seok-Ki;Jo, Hak-Jun
    • Journal of Korean Medical classics
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    • v.23 no.4
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    • pp.39-62
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    • 2010
  • Background : I investigated clinical research methodology of Traditional Korean Medicine(TKM) for treatment of lung cancer with Evidence Based Medicine(EBM) approach. Methods : I conducted the internet search of National Central Library, the National Assembly Library, Korea Education & Research Information Service, Korea Institute of Science and Technology Information for Korean theses and papers, and MEDLINE for the outside articles. Conclusion : In addition to outcomes of clinical trial, abundant clinician's experience and patients' preference are also considered. Pragmatic trials and quasi-experimental trials are better than clinical trials to plan clinical design of TKM for lung cancer and appropriate endpoints includes overall survival, disease-free survival, patient reporting outcome.

A Review of Studies on Antibiotic Course and Antibiotic Resistance in Nasopharyngeal Pathogens in Primary Care Setting (일차진료 항생제 치료기간과 비인두 항생제 내성률에 대한 연구 고찰)

  • Shin, Hyang Hwa;Lee, Sun Haeng;Yun, Sung Joong;Chang, Gyu Tae
    • The Journal of Pediatrics of Korean Medicine
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    • v.32 no.2
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    • pp.64-71
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    • 2018
  • Objectives The purpose of this study is to examine the correlation of antibiotics administration duration and antimicrobial resistance by reviewing domestic and foreign literatures. Methods We searched literatures dated up to 23 February, 2018 in PubMed and Cochrane Library using terms of "Anti-Bacterial Agents", "Carrier State", "Nasopharynx", "Drug Administration Schedule", and also searched via RISS (Research Information Service System), KISS (Koreanstudies Information Service System), DBpia (DataBase Periodical Information Academic) using terms of antibiotics, resistance, and dose. Results In comparison with shortened and standard antibiotic course, longer treatment duration is associated with greater antimicrobial resistance or non-significant difference, but we cannot find literature that shortened antibiotic course increases antimicrobial resistance on human nasopharyngeal flora. Conclusions Currently, there is no evidence that completing the standard antibiotic course reduces antimicrobial resistance. It can be a strategy for reducing antibiotic use to apply Korean medicine treatment, as well as short-course antibiotic therapy or delayed antibiotic prescription. Additional well-designed trials should be conducted in domestic and foreign settings about the appropriate duration of antibiotic therapy.

A Review Study of Treatments for Taeeumin Obesity (태음인 비만의 치료에 대한 임상 논문 분석)

  • Hur, Hansol;Kang, O-seok
    • Journal of Sasang Constitutional Medicine
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    • v.31 no.4
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    • pp.28-40
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    • 2019
  • Objectives The purpose of this study is to analyze how obesity of Taeeumin have been treated. Methods We searched clinical studies from the databases including Koreanstudies Information Service System(KISS), Oriental medicine Advanced Searching Integrated System(OASIS), Research Information Sharing Service(RISS), National Discovery for Science Leader(NDSL), Korea Citation Index(KCI) and pubmed with the keywords relevant to treatment of Taeeumin obesity. Results A total of 14 studies were analyzed. Herbal medicines were mostly used, and the most frequently used prescription was Taeeumjowi-tang. And concurrent therapies such as diet therapy, exercise therapy, electroacupuncture were performed. Several evaluation methods were used, and patient's body weight was the most used. Conclusion Through this literature review, we could find out tendencies of Korean medicine treatments of obesity of taeeumin up to date and some points that may have clinical significance.

Effects of Neuromuscular Electrical Stimulation on Muscle Wasting with Cancer Patient: Study Protocol for a Systematic Review (신경근전기자극치료가 암환자의 근육 손실에 미치는 영향: 체계적 문헌고찰을 위한 프로토콜)

  • Eun Soo Park;Jong Hee Kim;Soo Dam Kim;Dong Hyun Kim;Min Seok Oh;Eun Jung Lee;Hwa Seung Yoo
    • Journal of Korean Medicine Rehabilitation
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    • v.33 no.2
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    • pp.49-55
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    • 2023
  • Objectives The purpose of this study is to analyze randomized controlled trials about neuromuscular electrical stimulation for muscle wasting with cancer patient and evaluate it's motor functionality effect. Methods Studies will be searched from 7 online databases (PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure [CNKI], Korean studies Information Service System [KISS], Research Information Sharing Service [RISS], Oriental Medicine Advanced Searching Integrated System [OASIS]). Participants will be cancer patients with muscle loss, regardless of cause, gender, race or age, interventions will be neuromuscular electrical stimulation. Other treatments than interventions will be the control group and the main outcome will be reviewed by motor functionality effect. Results Randomized controlled trials about neuromuscular electrical stimulation for muscle wasting should be included in the study. Primary outcomes include motor functionality effect. Secondary outcomes evaluate adverse event. The data uses Review Manager Software 5.4. Conclusions The conclusion of this study will provide a basis for determining whether neuromuscular electrical stimulation treatment for muscle wasting with cancer patient treatment is an effective and safe treatment method in clinical practice.

Analysis of Influencing Factors on the Outpatient Prescription of Antipsychotic Drugs in the Elderly Patients (노인환자의 항정신병 약물 원외처방 내역에 미친 영향 요인 분석)

  • Dong, Jae Yong;Lee, Hyun Ji;Lee, Tae Hoon;Kim, Yujeong
    • Korean Journal of Clinical Pharmacy
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    • v.31 no.4
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    • pp.268-277
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    • 2021
  • Background: Most antipsychotic drugs studies have been mainly conducted on side effects, randomized clinical trials, utilization rates, and trends. But there have been few studies on the influencing factors in elderly patients. The purpose of this study was to analyze the influencing factors on the outpatient prescription of antipsychotic drugs in the elderly patients. Methods: Active ingredients of antipsychotic drugs in Korea were selected according to the Korean Pharmaceutical Information Center (KPIC)'s classification. Data source was Korean Health Insurance Review and Assessment Service (HIRA) claims data in 2020 and target patient group was the elderly patient group. We extracted patients who have been prescribed one or more antipsychotic drugs and visited only one medical institution. Data were analyzed using descriptive statistics, chi-square, t-test, negative binomial regression. Results: A number of outpatients were 245,197 and prescriptions were 1,379,092. Most characteristics of patients were 75-85 year's old, female, health insurance type, no disease (dementia, schizophrenia), atypical drugs, cci score (>2) and characteristics of medical institution were neurology in specialty, rural region, general hospitals. Results of regression showed that patient's characteristics and medical center characteristics had significant effect on the outpatient prescription of antipsychotic drugs in the elderly patients. Conclusion: This study suggests that national policy of antipsychotic drugs in the elderly patients, with the consideration of the patients' and medical institutions' characteristics, is needed.

A Study on the Effects of the Service Quality of Hospital's Decision Support System on Management Performance : the Case of K-University Hospital (병원 의사결정지원시스템의 서비스 품질이 경영성과에 미치는 영향 : K대병원 사례 중심으로)

  • Park, Jin Hee;Kwon, Do Soon;Lee, Miyoung
    • Journal of Information Technology Applications and Management
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    • v.21 no.2
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    • pp.81-98
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    • 2014
  • Recently, due to external environment like the changes in health policy and various healthcare accreditations, along with hospital's internal efforts to improve the quality of medical services, demands for the development of medical information systems are increasing. Some examples are clinical information like DUR (Drug Utilization Review), CVR (Critical Value Report), and automatic benefit processing by treatment purposes, or hospital DSS (Decision Support System) on overall medical practice. Such systems act as a guide in making clinic judgments during practice or in other medical practice, and their effects on the medical treatment improvements are being proven by previous studies. In the reality of increasing attention in the effects of medical treatment improvement, studies related to hospital DDS were mostly focused on clinical, technical, and engineering points of view, and studies focusing on the user viewpoint are very limited. In order to verify the effects of DSS on practice improvements and hospital's management performance, this study used a research model constructed to verify how SERVQUAL of hospital DSS affects hospital management performance in BSC (Balanced Score Card) point of view. To empirically verify the research model, a questionnaire was conducted on the basis of "K-University Hospital's DSS" on clinicians and hospital employees related to system development, and the relationships between the factors were analyzed through path analysis. As a result of path analysis, excluding reactivity, tangibility, confidence, reliability, empathy among service qualities, had partially significant effects on management performance factors (learning and growth, internal process, financial affairs). This study is to prepare the theoretical ground on the management performance analysis of hospital DSS, and suggest the service quality of the system that should be considered in the planning and development stages for improved system.

Status of the Development and Utilization of Critical Pathways in Medical Institutions in South Korea (국내 의료기관의 표준진료지침 개발 및 운영 현황)

  • Oh, In-Ohg;Chang, Tae-Ik;Kim, Hyun-Jin;Han, Jung-Mi;Lee, Chun-Kyon
    • Quality Improvement in Health Care
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    • v.28 no.1
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    • pp.2-13
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    • 2022
  • Purpose: This study assessed the status of the Development and Utilization of critical pathways (CP) in South Korea. Methods: We surveyed 195 hospitals obtained on the Korean Hospital Association website. Data were collected using structured questionnaires for staff members in charge of CP management personnel in these hospitals. The questionnaire included CP developed by the institutions, the coverage rates and completion rates of CP in the current year, and management indicators related to CP. The questionnaire also included CP support systems and content within the institutions and questions regarding the advantages of CP utilization and obstacles associated with the CP development process. Results: Analysis of the responses from 70 hospitals (35.9% response rate) showed that a total of 1,370 CP sets were developed. The number of CP related to surgery departments was 365 (26.6%), and CP related to surgery and procedure was 1,093 (79.8%), respectively. The CP coverage rate was the most frequently used indicator to monitor the effect of CP (97.1%), followed by the completion rate (90.0%) and the length of stay in hospital (61.4%). CP managers reported that CP were highly useful for communication (3.39±0.493) and accurate information provision (3.39±0.491). The perception that CP violated doctors' autonomy in treatment was relatively low (2.87±0.645). Conclusion: It is necessary to establish an infrastructure in hospitals for CP. CP can facilitate communication and provide accurate information.

The Analysis of the Recent Research Trend of Sipjeondabo-tang in Korea (국내 십전대보탕 최근 연구 동향 분석)

  • Oh, Somi;Cheon, Chunhoo;Park, Sunju;Jang, Bo-Hyoung;Park, Jeong-Su;Jang, Soobin;Shin, Yong-Cheol;Ko, Seong-Gyu
    • Journal of Society of Preventive Korean Medicine
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    • v.18 no.1
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    • pp.113-123
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    • 2014
  • Objective : This study is aimed to analyze the recent research trend of Sipjeondabo-tang (SJDBT) in Korea. Method : We searched Korean research database by using keyword 'Sipjeondabo-tang'. Databases are Korean Medicine Information System, Research Information Service System and Korean Studies Information Service System. We analyzed studies by research method, publication year, type of journal and subject of the study. Results : By analyzing studies published after 1990, we could find that experimental studies were primarily conducted in SJDBT study. During recent 10 years, the number of toxicity studies and components analysis studies is increasing. Among the SJDBT studies, the number of clinical study was only 1. Conclusion : We explored the recent research trend of SJDBT in Korea. As a result, We suggested three further research ways of SJDBT. Proposed research ways are exploring various effect of SJDBT, observing whether there is a difference of effect according to extracting and drying method, and conducting clinical research of SJDBT.

Review of Clinical Research of Korean Medicine on Postpartum Pelvic Organ Prolapse (산후 골반장기탈출증에 대한 한의학적 임상 연구 동향)

  • Park, Nam-Gyeong;Hwang, Young-Sik;Kim, Gyu-Tae;Park, Seung-Hyeok;Lee, Jin-Moo;Lee, Chang-Hoon;Jang, Jun-Bock;Hwang, Deok-Sang
    • The Journal of Korean Obstetrics and Gynecology
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    • v.33 no.4
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    • pp.93-112
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    • 2020
  • Objectives: The purpose of this study is to review the clinical research trends of postpartum pelvic organ prolapse and to recognize the efficacy of Korean medicine intervention. Methods: Based on seven domestic and foreign databases, including Research Information Sharing Service (RISS), Oriental Medicine Advanced Searching Integrated System (OASIS), Journal of Korean Obstetric and Gynecology, Cochrane Library Central, Pubmed, China National Knowledge Infrastructure (CNKI) and WangFang Med Online, we analyzed the clinical trials using Korean medicine intervention, which included acupuncture and herbal medicine. Data retrieval was carried out on May 18 to 20, 2020, and a total of 13 papers were included. Results: All papers were published in China and it contains nine randomized controlled trials, three clinical trials, and one case. The most frequently used intervention was herbal medicine, and Bupleuri Radix, Cimicifugae Rhizoma were used. The treatment group treated by Korean medicine intervention was more effective than the control group. Also, there were no significant side effects of Korean medicine. Conclusion: This study shows that Korean medicine can be effective and safe medical alternatives or options for pelvic organ prolapse patients. However, to laying the foundation of clinical guidelines and applying it to the real-world clinical scene, further follow-up research is needed.

Study for Clinicians' Perception on the Acupuncture Research and Ways to Symbiosis between Basic Research and Clinical Practice (침 연구에 대한 한의사의 인식과 연구방향에 대한 조사)

  • Kim, Song-Yi;Chae, Youn-Byoung;Lee, Hyang-Sook;Ko, Yu-Mi;Lee, Hye-Jung;Park, Hi-Joon
    • Korean Journal of Acupuncture
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    • v.29 no.2
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    • pp.224-238
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    • 2012
  • Objectives : From mechanism studies using animal models to high-level evidence based research such as randomized controlled trials or systematic reviews, various acupuncture studies have been performed. Nevertheless, the current research appears insufficient to satisfy clinicians' needs. We aimed at investigating clinicians' perception on the translational research and suggesting ways of symbiosis between basic research and clinical practice. Methods : Data were collected using a web-based questionnaire made available to Korean medicine doctors who were informed through social networking service or e-mail. The survey participants indicated their awareness of acupuncture research and their thoughts on the applicability of research in practice. Results : Forty-seven clinicians completed the survey. While most respondents agreed that acupuncture research is very important, only 40% of them answered that the results of acupuncture research are useful to their own practice. In more than half of those who responded to the survey, the current acupuncture research is not viewed as reflecting clinical practice very much. Respondents agreed that acupuncture research should be based on clinical practice, and they recognized the need to collect valid clinical data from real-world practice. Also, as many as 77% of clinicians had no scruple to participate in research programs. Conclusions : There is no doubt among practitioners that acupuncture research is necessary. More importantly, practice-based research remains essential in order to feed-back research outcomes to clinical practice. Communications and academic exchanges between clinicians and researchers can mutually benefit research and practice with better information, resulting in symbiosis.