• Maxillofacial Plastic and Reconstructive Surgery
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• 제14권1_2호
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• pp.124-134
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• 1992

Fibrous dysplasia is a benign pathologic condition of bone in which fibrous tissue gradually expands and replaces normal bone into fibro-osseous lesion. It is a primary developmental abnormality of bone-forming mesenchyme in origin. This study shows clinical history, radiological and histopathological feature of fibrous dysplasia with the intention of establishing correct diagnosis, treatment plan and evaluation of prognosis. This paper reviews and summarizes the materials from 57 fibrous dysplasias submitted to the Department of Oral and Maxillofacial Surgery in College of Dentistry, Seoul National University. Conclusions obtained were as following : 1. Fibrous dysplasia developed mainly in teenagers and shows female predeliction. 2. Fibrous dysplasia developed much on the maxilla 3. Monostotic fibrous dysplasia was most popular form. 4. Main symptom of fibrous dysplasia was painless swelling. 5. Radiological feature of fibrous dysplasia was ground-glass appearance, 6. Histopathological feature of fibrous dysplasia was irregular immature bony trabeculae(woven bone). 7. Treatment of fibrous dysplasia was mainly conservative contouring surgery.

• 치과방사선
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• 제14권1호
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• pp.169-172
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• 1984

The author observed a cystic lesion which had new radiographic entities in the 6 years old male patient and obtained the following features. 1. The main clinical feature is the swelling. 2. The lesion is situated on the buccal surface of a erupting mandibular first molar. 3. The affected molar is tilted, so that the apices are adjacent to the lingual plate of the mandible. 4. The affected molar is of normal morphology, caries-free and vital. 5. The radiographic feature is the cystic radiolucency which is extended over the buccal surface of the roots of the affected molar and slightly inferior to the root apices. 6. The dental papilla of the affected molar shows the lamina dura of relatively normal density and definitition. 7. The buccal surface shows the laminated new bone formation. 8. The inferior concave border of the lesion is delineated by a thick and calcified layer of cortical bone. 9. The lesion causes displacement of the developing second molar of which anterior cortex is partially destroyed.

• 수면정신생리
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• 제9권2호
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• pp.100-105
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• 2002

Personality traits in insomniac patients have been a subject of many studies. A number of these studies have used the MMPI and have demonstrated elevated scores on several clinical scales reflecting somatic concerns, somatization, depression, anxiety, worry and social alienation. And it was suggested that insomnia was due to a process of internalization of psychological distress. Another hypothesis about psychological mechanisms has focused upon worry. Excessive and uncontrollable cognitive activity seem to be a characteristic feature of many insomniacs. One author emphasized the role of the dependency need and found a characteristic pattern among insomniacs. The central feature of this pattern is frustration of dependency need. The purpose of this paper was to review possible personality variable that may be predisposing causal factors of insomnia. Several factors are suggested by many studies, but in order to explore their causal importance other experimental and longitudinal studies are needed.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제18권1호
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• pp.60-65
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• 2015

We report a pediatric patient admitted with abdominal pain, diffuse lower extremity edema and watery diarrhea for two months. Laboratory findings including complete blood count, serum albumin, lipid and immunoglobulin levels were compatible with protein losing enteropathy. Colonoscopic examination revealed diffuse ulcers with smooth raised edge (like "punched out holes") in the colon and terminal ileum. Histopathological examination showed active colitis, ulcerations and inclusion bodies. Immunostaining for cytomegalovirus was positive. Despite supportive management, antiviral therapy, the clinical condition of the patient worsened and developed disseminated cytomegalovirus infection and the patient died. Protein losing enteropathy and disseminated cytomegalovirus infection a presenting of feature in steroid-naive patient with inflammatory bowel disease is very rare. Hypogammaglobulinemia associated with protein losing enteropathy in Crohn's disease may predispose the cytomegalovirus infection in previously healthy children.

• 대한의용생체공학회:의공학회지
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• 제32권3호
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• pp.237-244
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• 2011

In this paper, a feature-based registration technique is proposed for pre-contrast and post-contrast lung CT images. It utilizes three dimensional(3-D) features with their descriptors and estimates feature correspondences by nearest neighborhood matching in the feature space. We design a transformation model between the input image pairs using a free form deformation(FFD) which is based on B-splines. Registration is achieved by minimizing an energy function incorporating the smoothness of FFD and the correspondence information through a non-linear gradient conjugate method. To deal with outliers in feature matching, our energy model integrates a robust estimator which discards outliers effectively by iteratively reducing a radius of confidence in the minimization process. Performance evaluation was carried out in terms of accuracy and efficiency using seven pairs of lung CT images of clinical practice. For a quantitative assessment, a radiologist specialized in thorax manually placed landmarks on each CT image pair. In comparative evaluation to a conventional feature-based registration method, our algorithm showed improved performances in both accuracy and efficiency.

• 대한치과의사협회지
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• 제53권10호
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• pp.712-725
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• 2015

The clinical dentistry system and research tendency of dentistry in North Korea has a difference with South Korea. In North Korea, preventive dentistry has been developed, and government of North Korea clame a free medical service to all the people. And there are tendency that Korean medicine(Oriental medicine) is applied to clinical dentistry in North Korea. Research tendency of dentistry in North Korea have a difference from South Korea. Articles of dentistry in North Korea have some freatures. Terminology of dentistry is writtened in original Korean developed uniquely in North Korea. Recent articles of dentistry in North Korea have a reference from english articles, and it is different that reference articles in the past were from Chinese or Russian articles. In order to get ready for the United Korea, we need to know the feature of dentistry in North Korea, and increase an academic exchange between South and North Korea.

• 한국임상약학회지
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• 제26권1호
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• pp.84-95
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• 2016

Objective: Atrial fibrillation (AF) guidelines have been published in the USA and Europe. Recently, the USA and Europe have updated their guidelines, respectively. These new AF guidelines help in addressing key management issues in clinical situations. This study, therefore, systematically compared guidelines for rate and rhythm control pharmacotherapy of patients with AF between the USA (American College of Cardiology and American Heart Association, ACC/AHA) and Europe (European Society of Cardiology, ESC). Methods: This study investigated and compared American guidelines (2014) and European guidelines (2010 and 2012). Results: Generally, there are four meaningful differences between ACC/AHA and ESC guidelines. Important differences are treatment classification system, level of recommendation, drug list, and dosage. In addition, ACC/AHA described pharmacokinetic drug interactions for antiarrhythmic drugs. ESC emphasized ECG and atrioventricular nodal slowing as feature of antiarrhythmic drugs. Conclusion: This research addresses important use of anti-arrhythmic drugs and movement to accept recent recommendations in Korea. For the successful application of the guidelines, a role of pharmacists is crucial in clinical situation.

• 한방재활의학과학회지
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• 제23권3호
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• pp.149-157
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• 2013

Objectives This study was designed to: (1) investigate the clinical feature of tongue diagnosis, (2) make an observation of significant changes in tongue diagnosis according to the patient's physical condition and laboratory result and (3) identify clinical efficacy of tongue diagnosis. Methods 300 patients' tongue diagnosis results were analyzed and the patients were divided to each group according to the physical condition and laboratory result. Then, chi-square test was performed to assess statistical significance between tongue diagnosis results of each group. Results As a result of analyzing the spread of tongue diagnosis according to the patient's physical condition and laboratory result, 18 groups had statistical significance related to specific tongue color and tongue coating. Conclusions Even if there would be possible misinterpretations in one-to-one match between the tongue diagnosis and certain diseases, we identified that tongue diagnosis results were changed somewhat related to patient's physical condition with some tendency and tongue diagnosis could be used for meaningful clinical diagnostic tool.

• 한국멀티미디어학회논문지
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• 제13권5호
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• pp.722-729
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• 2010

예측 문제를 해결하기 위한 데이타마이닝 기법은 다양한 분야에서 주목받고 있다. 이것에 대한 한 예로 컴퓨터-기반의 질병의 예측 혹은 진단은 CDSS(Clinical Decision support System)에서 가장 중요한 요소이기도 하다. 이러한 예측 문제를 해결하기 위해서 RBF커널 같은 비선형 커널을 사용한 SVM이 가장 널리 사용되고 있는데, 이는 비선형 SVM이 어떠한 다른 분류기법보다 정확한 성능을 보이기 때문이다. 하지만 비선형 SVM을 사용한 경우에는 모델내부를 시각화하는 일이 어려워서 예측결과에 대한 직관적인 이해가 힘들고, 의학 전문가들은 이러한 비선형 SVM의 사용을 기피하고 있는 실정이다. Nomogram은 SVM을 시각화하기 위해 제안된 기법이다. 하지만 이는 선형 SVM의 경우에만 사용이 가능하고. 이 문제를 해결하기 위해서 LRBF 커널이 제안된 바 있다. LRBF 커널은 기존의 RBF 커널을 사용한 SVM과 대등한 결과를 보이면서도 예측결과의 선형적 분석도 가능하게 한다. 본 논문에서는 노모그램(Nomogram)과 LRBF 커널을 사용한 SVM이 통합되어 있는 예측 툴 VRIFA를 제안한다. 이 툴은 사용자와 상호작용하며 비선형 SVM 모델의 내부구조를 데이타의 각 속성별로 보여주는 방법으로 사용자가 예측결과를 직관적으로 이해하도록 도와준다. VRIFA는 Nomogram기반의 피쳐선택(feature selection) 기능도 포함하고 있는데, 이 기능은 예측결과에 부정적인 영향을 끼치거나 중복된 연관성을 보이는 속성을 제거함으로써 모델의 정확도를 높이는 데 기여한다. 그리고 데이터에 포함된 클래스의 비율이 한 쪽으로 치우쳐져 있는 경우에는 ROC 곡선 넓이(AUC)를 예측결과를 평가하기 위한 측도로 사용할 수 있다. 이 툴은 컴퓨터-기반의 질병 예측 혹은 질병의 위험 요소 분석에 대해 연구하는 연구자들에게 유용하게 사용될 것으로 전망하는 바이다.

• 정신신체의학
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• 제29권2호
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• pp.144-152
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• 2021

연구목적 본 연구는 응급실에 내원한 졸피뎀 음독 자살시도군과 다른 방법을 사용한 자살시도군을 비교하여 차이를 확인하고자 하였다. 방 법 2009년부터 2018년까지 응급실에 내원한 총2734명의 자살시도자를 대상으로 졸피뎀 음독 자살시도군, 졸피뎀 외 약물 음독 자살시도군, 비약물 자살시도군으로 분류하였으며, 세 군에 대하여 사회인구학적 특성, 자살시도와 관련된 임상적 특성들에 대해 교차분석과 회귀분석을 수행하였다. 결 과 졸피뎀 음독 자살시도군과 비약물적 자살시도군에서 차이를 보인 변수들에 대한 회귀 분석 결과에서, 안정제/수면제의 사용과 치명도가 낮거나 의도의 심각성이 높지 않은 경우가 졸피뎀 음독 자살시도의 발생과 연관성이 있었다. 유사한 특성을 보인 음독군 내에서도 안정제/수면제의 사용은 졸피뎀 음독 자살시도의 발생과 연관성이 있었다. 결 론 본 연구에서는 응급실에 내원한 졸피뎀 음독 자살시도군과 다른 방법을 사용한 자살시도군의 사회인구학적, 임상적 특성의 유의한 차이를 확인하였다. 이러한 결과는 추후 졸피뎀을 사용하는 것에 대한 약물적 치료를 계획하는데 도움이 될 수 있다.