• Title/Summary/Keyword: Clinical Decision Rules

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Extraction of Hierarchical Decision Rules from Clinical Databases using Rough Sets

  • Tsumoto, Shusaku
    • Proceedings of the Korea Inteligent Information System Society Conference
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    • 2001.01a
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    • pp.336-342
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    • 2001
  • One of the most important problems on rule induction methods is that they cannot extract rules, which plausibly represent experts decision processes. On one hand, rule induction methods induce probabilistic rules, the description length of which is too short, compared with the experts rules. On the other hand, construction of Bayesian networks generates too lengthy rules. In this paper, the characteristics of experts rules are closely examined and a new approach to extract plausible rules is introduced, which consists of the following three procedures. First, the characterization of decision attributes (given classes) is extracted from databases and the classes are classified into several groups with respect to the characterization. Then, two kinds of sub-rules, characterization rules for each group and discrimination rules for each class in the group are induced. Finally, those two parts are integrated into one rule for each decision attribute. The proposed method was evaluated on a medical database, the experimental results of which show that induced rules correctly represent experts decision processes.

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Semantic Web-based Clinical Decision Support System for Armed Forces Hospitals (군 병원을 위한 시맨틱 웹 기반 진료 의사결정지원 시스템)

  • Yoo, Dong-Hee;Ra, Min-Young
    • The KIPS Transactions:PartB
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    • v.17B no.4
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    • pp.317-326
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    • 2010
  • To improve the diagnosis and prescription for military personnel, it is required to adopt Clinical Decision Support System (CDSS) in armed forces hospitals. The objective of this paper is to suggest a CDSS for armed forces hospitals using semantic web technologies. To this end, we designed military medical ontologies and military medical rules which consist of the various concepts and rules for supporting medical activities. We developed a semantic web-based CDSS to demonstrate the use of the ontologies and rules for treating military patients. We also showed the process of semantic search for the medical records which are created from the semantic web-based CDSS.

A Study on Decision Rules for Qi·Blood·Yin·Yang Deficiency Pathogenic Factor Based on Clinical Data of Diagnosis System of Oriental Medicine (한방진단설문지 임상자료에 근거한 기혈음양 허증병기 의사결정규칙 연구)

  • Soo Hyung Jeon;In Seon Lee;Gyoo yong Chi;Jong Won Kim;Chang Wan Kang;Yong Tae Lee
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.37 no.6
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    • pp.172-177
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    • 2023
  • In order to deduce the pathogenic factor(PF) diagnosis logic of underlying in pattern identification of Korean medicine, 2,072 cases of DSOM(Diagnosis System of Oriental Medicine) data from May 2005 to April 2022 were collected and analyzed by means of decision tree model(DTM). The entire data were divided into training data and validation data at a ratio of 7:3. The CHAID algorithm was used for analysis of DTM, and then validity was tested by applying the validation data. The decision rules of items and pathways determined from the diagnosis data of Qi Deficiency, Blood Deficiency, Yin Deficiency and Yang Deficiency Pathogenic Factor of DSOM were as follows. Qi Deficiency PF had 7 decision rules and used 5 questions: Q124, Q116a, Q119, Q119a, Q55. The primary indicators(PI) were 'lack of energy' and 'weary of talking'. Blood deficiency PF had 7 decision rules and used 6 questions: Q113, Q84, Q85, Q114, Q129, Q130. The PI were 'numbness in the limbs', 'dizziness when standing up', and 'frequent cramps'. Yin deficiency PF had 3 decision rules and used 2 questions: Q144 and Q56. The PI were 'subjective heat sensation from the afternoon to night' and 'heat sensation in the limbs'. Yang deficiency PF had 3 decision rules and used 3 questions: Q55, Q10, and Q102. The PI were 'sweating even with small movements' and 'lack of energy'. Conclusively, these rules and symptom information to decide the Qi·Blood·Yin·Yang Deficiency PF would be helpful for Korean medicine diagnostics.

Podiatric Clinical Diagnosis using Decision Tree Data Mining (결정트리 데이터마이닝을 이용한 족부 임상 진단)

  • Kim, Jin-Ho;Park, In-Sik;Kim, Bong-Ok;Yang, Yoon-Seok;Won, Yong-Gwan;Kim, Jung-Ja
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.48 no.2
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    • pp.28-37
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    • 2011
  • With growing concerns about healthy life recently, although the podiatry which deals with the whole area for diagnosis, treatment of foot and leg, and prevention has been widely interested, research in our country is not active. Also, because most of the previous researches in data analysis performed the quantitative approaches, the reasonable level of reliability for clinical application could not be guaranteed. Clinical data mining utilizes various data mining analysis methods for clinical data, which provides decision support for expert's diagnosis and treatment for the patients. Because the decision tree can provide good explanation and description for the analysis procedure and is easy to interpret the results, it is simple to apply for clinical problems. This study investigate rules of item of diagnosis in disease types for adapting decision tree after collecting diagnosed data patients who are 2620 feet of 1310(males:633, females:677) in shoes clinic (department of rehabilitation medicine, Chungnam National University Hospital). and we classified 15 foot diseases followed factor of 22 foot diseases, which investigated diagnosis of 64 rules. Also, we analyzed and compared correlation relationship of characteristic of disease and factor in types through made decision tree from 5 class types(infants, child, adolescent, adult, total). Investigated results can be used qualitative and useful knowledge for clinical expert`s, also can be used tool for taking effective and accurate diagnosis.

Analysis on Relation between Rehabilitation Training Movement and Muscle Activation using Weighted Association Rule Discovery (가중연관규칙 탐사를 이용한 재활훈련운동과 근육 활성의 연관성 분석)

  • Lee, Ah-Reum;Piao, Youn-Jun;Kwon, Tae-Kyu;Kim, Jung-Ja
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.46 no.6
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    • pp.7-17
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    • 2009
  • The precise analysis of exercise data for designing an effective rehabilitation system is very important as a feedback for planing the next exercising step. Many subjective and reliable research outcomes that were obtained by analysis and evaluation for the human motor ability by various methods of biomechanical experiments have been introduced. Most of them include quantitative analysis based on basic statistical methods, which are not practical enough for application to real clinical problems. In this situation, data mining technology can be a promising approach for clinical decision support system by discovering meaningful hidden rules and patterns from large volume of data obtained from the problem domain. In this research, in order to find relational rules between posture training type and muscle activation pattern, we investigated an application of the WAR(Weishted Association Rule) to the biomechanical data obtained mainly for evaluation of postural control ability. The discovered rules can be used as a quantitative prior knowledge for expert's decision making for rehabilitation plan. The discovered rules can be used as a more qualitative and useful priori knowledge for the rehabilitation and clinical expert's decision-making, and as a index for planning an optimal rehabilitation exercise model for a patient.

The Development of Clinical Decision Support System for Diagnosing Neurogenic Bladder

  • Batmunh, Nyambat;Chae, Young M.
    • Proceedings of the Korea Inteligent Information System Society Conference
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    • 2001.01a
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    • pp.478-485
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    • 2001
  • In this study, we have developed a prototype of clinical decision support systems (CDSS) for diagnosing neurogenic bladder and compared its predicted diagnoses with the actual diagnoses using 92 patient\`s Urodynamic study cases. The CDSS was developed using a Visual Basic based on the evidence-based rules extracted from guidelines and other references regarding a diagnosis of neurogenic bladder. To compare with the 92 final diagnoses made by doctors at the Yonsei Rehabilitation Center, we classified all diagnoses into 5 groups. The predictive rates of the CDSS were: 48.0% for areflexic neurogenic bladder; 60.0% for hyperreflexic neurogenic bladder in a spinal shock recovery stage; 72.9% for hyperreflexic neurogenic bladder, and 80.0% for areflexic neurogenic bladder in a spinal shock stage, which was the highest predicted rate. There were only 2 cases for hyperreflexic neurogenic bladder in a well controlled detrusor activity, and its predictive rate was 0%. The study results showed that CDSS for diagnosing neurogenic bladder could provide a helpful advice on decision-making for doctors. The findings also suggest that physicians should be involved in all development stages to ensure that systems are developed in a fashion that maximizes their beneficial effect on patient care, and that systems are acceptable to both professionals and patients. The future studies will concentrate on including more validating the system.

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Development and Validation of a Prediction Model: Application to Digestive Cancer Research (예측모형의 구축과 검증: 소화기암연구 사례를 중심으로)

  • Yonghan Kwon;Kyunghwa Han
    • Journal of Digestive Cancer Research
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    • v.11 no.3
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    • pp.157-164
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    • 2023
  • Prediction is a significant topic in clinical research. The development and validation of a prediction model has been increasingly published in clinical research. In this review, we investigated analytical methods and validation schemes for a clinical prediction model used in digestive cancer research. Deep learning and logistic regression, with split-sample validation as an internal or external validation, were the most commonly used methods. Furthermore, we briefly introduced and summarized the advantages and disadvantages of each method. Finally, we discussed several points to consider when conducting prediction model studies.

Introduction to Evidence-based Medicine (EBM) (Evidence-Based Medicine에 대한 소개)

  • Choe, Jae-Gol
    • The Korean Journal of Nuclear Medicine
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    • v.35 no.4
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    • pp.224-230
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    • 2001
  • EBM is "the conscientious, explicit and judicious use of current best evidence in mating decisions about the care of the individual patient. It means integrating individual clinical expertise with the best available external clinical evidence from systematic research." EBM is the integration of clinical expertise, patient values, and the best evidence into the decision making process for patient care. The practice of EBM is usually triggered by patient encounters which generate questions about the effects of therapy, the utility of diagnostic tests, the prognosis of diseases, or the etiology of disorders. The best evidence is usually found in clinically relevant research that has been conducted using sound methodology. Evidence-based medicine requires new skills of the clinician, including efficient literature-searching, and the application of formal rules of evidence in evaluating the clinical literature. Evidence-based medicine converts the abstract exercise of reading and appraising the literature into the pragmatic process of using the literature to benefit individual patients while simultaneously expanding the clinician's knowledge base. This review will briefly discuss about concepts of evidence medicine and method of critical appraisal of literatures.

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Generating Rank-Comparison Decision Rules with Variable Number of Genes for Cancer Classification (순위 비교를 기반으로 하는 다양한 유전자 개수로 이루어진 암 분류 결정 규칙의 생성)

  • Yoon, Young-Mi;Bien, Sang-Jay;Park, Sang-Hyun
    • The KIPS Transactions:PartD
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    • v.15D no.6
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    • pp.767-776
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    • 2008
  • Microarray technology is extensively being used in experimental molecular biology field. Microarray experiments generate quantitative expression measurements for thousands of genes simultaneously, which is useful for the phenotype classification of many diseases. One of the two major problems in microarray data classification is that the number of genes exceeds the number of tissue samples. The other problem is that current methods generate classifiers that are accurate but difficult to interpret. Our paper addresses these two problems. We performed a direct integration of individual microarrays with same biological objectives by transforming an expression value into a rank value within a sample and generated rank-comparison decision rules with variable number of genes for cancer classification. Our classifier is an ensemble method which has k top scoring decision rules. Each rule contains a number of genes, a relationship among involved genes, and a class label. Current classifiers which are also ensemble methods consist of k top scoring decision rules. However these classifiers fix the number of genes in each rule as a pair or a triple. In this paper we generalized the number of genes involved in each rule. The number of genes in each rule is in the range of 2 to N respectively. Generalizing the number of genes increases the robustness and the reliability of the classifier for the class prediction of an independent sample. Also our classifier is readily interpretable, accurate with small number of genes, and shed a possibility of the use in a clinical setting.

Knowledge Discovery in Nursing Minimum Data Set Using Data Mining

  • Park Myong-Hwa;Park Jeong-Sook;Kim Chong-Nam;Park Kyung-Min;Kwon Young-Sook
    • Journal of Korean Academy of Nursing
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    • v.36 no.4
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    • pp.652-661
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    • 2006
  • Purpose. The purposes of this study were to apply data mining tool to nursing specific knowledge discovery process and to identify the utilization of data mining skill for clinical decision making. Methods. Data mining based on rough set model was conducted on a large clinical data set containing NMDS elements. Randomized 1000 patient data were selected from year 1998 database which had at least one of the five most frequently used nursing diagnoses. Patient characteristics and care service characteristics including nursing diagnoses, interventions and outcomes were analyzed to derive the meaningful decision rules. Results. Number of comorbidity, marital status, nursing diagnosis related to risk for infection and nursing intervention related to infection protection, and discharge status were the predictors that could determine the length of stay. Four variables (age, impaired skin integrity, pain, and discharge status) were identified as valuable predictors for nursing outcome, relived pain. Five variables (age, pain, potential for infection, marital status, and primary disease) were identified as important predictors for mortality. Conclusions. This study demonstrated the utilization of data mining method through a large data set with stan dardized language format to identify the contribution of nursing care to patient's health.