• 제목/요약/키워드: Clinic research

검색결과 1,990건 처리시간 0.027초

고지방식이 비만마우스 모델에서 파키스탄산 및 중국산 마황으로 조성된 강지환(降脂丸)-1, 2, 3, 4와 강지환(降脂丸)-1합가미소체환(合加味消滯丸)의 체중감량효과 비교 (Comparison of Gangji-hwan-1, 2, 3, 4 and Combination of Gangji-hwan-1 and Gamisoche-hwan in the Reducing Effects of Body Weight in a High Fat Diet-Fed Obese Mice)

  • 유재상;구자룡;윤기현;조주흠;장두현;정양삼;김종훈;김병출;석화준;윤미정;노종성;신순식
    • 한방비만학회지
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    • 제15권1호
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    • pp.9-23
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    • 2015
  • Objectives: This study was investigated the improvement effects of Pakistani Ephedra herba-containing Gangji-hwan-1, 2, 3 (Di-fatty; DF-1, 2, 3), Chinese Ephedra herba-containing Gangjihwan-4 (DF-4) and combination of DF-1 and Gamisoche-hwan (GSH) on obesity in a high fat diet-fed obese mouse model. Methods: Eight-week-old C57BL/6N mice were divided into seven groups: a normal lean group given a standard diet, an obese control group given a high fat diet, and DF-1, 2, 3, 4, and DF-1+GSH groups given a high fat diet with DF-1, 2, 3, 4 (40, 80, 160, 80 mg/kg), and DF-1+ GSH (80 mg/kg), respectively. After 8 weeks of treatment, body weight gain, feeding efficiency ratio (FER), blood lipid markers, liver histology, and fat weight and histology were examined. Results: Body weight gain was significantly decreased in DF and DF-1+GSH groups compared with control. The extent of decreases was eminent in DF-1+GSH group. FER and circulating concentration of leptin were decreased in DF and DF-1+GSH groups compared with control. Circulating concentrations of triglyceride, glucose and insulin were decreased in DF and DF-1+GSH groups compared with control. The size of adipocytes were decreased by DF and DF-1+GSH groups compared with control, whereas the adipocyte number per unit area was increased by them, suggesting that DF and DF-1+GSH groups decreased the number of large adipocytes. Conclusions: In conclusion, these results suggest that DF and DF-1+GSH groups decrease FER, plasma leptin concentration, blood anti-obesity biomarkers and fat mass, improves body weight gain. In addition, these effects were more effective in DF-1+GSH combination group than in DF-1, 2, 3, 4 groups.

식이 자기 효능감: 한국어판 Weight Efficacy Life-Style 설문지 개발 - 횡문화적 번역 및 안면 타당도 검증 (Eating Self-Efficacy: Development of a Korean Version of the Weight Efficacy Life-Style Questionnaire - A Cross-Cultural Translation and Face-Validity Study)

  • 서희연;옥지명;김서영;임영우;박영배
    • 한방비만학회지
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    • 제19권1호
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    • pp.24-30
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    • 2019
  • Objectives: Eating self-efficacy is an important predictor of successful weight control behaviors during obesity treatment. The Weight Efficacy Life-Style Questionnaire (WEL) is an internationally used measure of eating self-efficacy. The objective of this study was to develop the Korean version of WEL (K-WEL) and verify face validity. Methods: According to previously published guidelines, the cross-cultural translation was conducted through organizing the expert committee, translation, back-translation, synthesis, grammar review, and final synthesis. Following the translation of the WEL into Korean, face validity was performed for 35 subjects. Results: After all the versions of the questionnaire were examined, the translated WEL questionnaires were finally synthesized and licensed by the developer in writing. Regarding the translated WEL questionnaires, seven out of 35 subjects (20%) offered ideas about ambiguous expressions in them. All four points indicated in the face validity verification were additionally modified for greater clarity and understanding. Conclusions: We developed the Korean version of WEL and completed face validity. In future research, it would be necessary to provide further study on the reliability and validity of the Korean version of WEL.

Determinants of Revisit Intention Among Indonesian Beauty Clinic Customers in Distribution Beauty Clinic Market: The Mediating Role of Trust

  • Anas HIDAYAT;Binarinta Tirto ANDIKA;Sri Rejeki EKASASI
    • 유통과학연구
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    • 제22권2호
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    • pp.31-40
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    • 2024
  • Purpose: This study aimsto assert trust as an important mediator in the service business. The research topic relatesto service businesses that have low exposure to comparative information and weak consumer positions in terms of law, such as the beauty clinic businesses in Indonesia. Research design, data, and methodology: This study uses explanatory and purposive sampling. A survey was conducted among 268 Indonesians, collected by distribution via Google Forms. The hypotheses were tested using AMOS software. Results: The results indicate that trust did not have a significant role in mediating brand awareness, service quality, and price perception on revisit intention, but only mediated satisfaction. Furthermore, this study discloses the neutralization attitude and dissonance behavior represented by trust mediation. Conclusions: These findings attempt to expand the literature on the role of trust in the service business. However, the beauty clinic businessin Indonesia infers misbehavior. Misbehavior is caused by vulnerable conditionsin which consumers are unable to share their experiences with other consumers. The reason is that the defamation law in Indonesia is often implemented in the wrong direction. This must be corrected so that consumers obtain their rights and create a mutually beneficial relationship between beauty businesses and consumers.

협동유우진료소(協同乳牛診療所)를 중심(中心)한 서울근교(近郊) 유우질환(乳牛疾患)의 연간조사보고(年間調査報告) (A One-Year Analysis of Dairy Cow Diseases of Seoul Area at Hyup Dong Large Animal Clinic)

  • 정창국;남정현;김정배;서정순;최중범;박근영
    • 대한수의학회지
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    • 제6권1호
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    • pp.53-56
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    • 1966
  • Number of dairy cow patients treated at Hyup Doug Large Animal Clinic during the year July 1,1965, through June 30, 1966, were amounted to 485 cases and the result of analysis of disease incidence during one year period were us follows; 1. In the etiologic diagnostic categories, diseases caused by static mechanical abnormality were most productive and 28.1% of all diagnoses involved in this category. 2. In the topographic diagnostic categories, 39.4% of all diagnoses involved the urogenital system and were obeserved most productive. 3. As a result of each topographic diagnostic categories were subdivided into disease entities, 13.4% of all diagnoses involved the retained placenta and this were observed most productive in the miscellaneous disease enties. Next productive diseases were miscellaneous ovarian disease (10.9%), indigestion (10.3%), mastitis (8.0%) and metritis (6.8%) chronologically.

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THAMS Clinic Camp 운영을 통한 융합인재 양성 방안 연구 (A Study to Train Student with Interdisciplinary Abilities through THAMS Clinic Camp)

  • 전영선;서태원
    • 공학교육연구
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    • 제18권6호
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    • pp.80-87
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    • 2015
  • The aim of this study suggest the THAMS Clinic Camp program to train the interdisciplinary students with humanistic knowledge as well as the skills to perform the scientific and engineering works. Since the future of society is required students with the ability to elicit an emotional empathy, THAMS Clinic Camp program has been planed and performed from year 2012 based on the comprehensive liberal learning. The average employment rate over the past three years of the students who participated in THAMS Clinic Camp program showed 7% better than the overall average employment rate of Andong National University. The another visible educational outcomes of the THAMS Clinic Camp program are following; i) To take place the conversion of recognition for the interdisciplinary activity by breaking down the walls between fragmented disciplines to students and ii) To provide the opportunity that students will understand the past and refocus the current to have the idea to plan for the future in the right direction.

Predictive Value of Malignancy Risk Indices for Ovarian Masses in Premenopausal and Postmenopausal Women

  • Ertas, Sinem;Vural, Fisun;Tufekci, Ertugrul Can;Ertas, Ahmet Candost;Kose, Gultekin;Aka, Nurettin
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권4호
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    • pp.2177-2183
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    • 2016
  • Background: To evaluate the predictive role of a risk of malignancy index in discriminating between benign and malignant adnexal masses preoperatively. Materials and Methods: A total of 408 patients with adnexal masses managed surgically between January 2010 and February 2014 were included. The risk of malignancy indices (RMI) 1, 2, 3 and 4 were calculated using findings for ultrasonography, menopausal status, and CA125 levels. Histopathologic results were the end point. ROC analysis was used for the sensitivity and the specificity of the models. Results: Some 37.6 % of the cases were malignant in the postmenopausal group while 7.9 % were malignant in the premenopausal group. Pelvic pain was the most common complaint, and the majority of the cases were diagnosed at stage 3. The RMI 1, 2, 3 and 4 yielded percentage sensitivities of 76.1, 79.1, 76.1 and 76.1 and specificities of 91.5, 89.1, 90.6, 88.6, respectively. RMI 1 was the most reliable test in the general population according to AUC levels and Kappa statistics. From ROC analysis results of post/premenopausal women, the RMI 1 (cut off: 200) yielded sensitivities of 84.0/60.9 and specificities of 87.7/92.5. With RMI 2 they were 88.6/60.9 and 80.0/91.0, with RMI 3 84.0/60.9 and 87.7/91.8, and with RMI 4 (cut off:400) 81.8/47.8 and 83.6 /44.0. Although test performance of RMI methods were good in a general population and postmenopausal women, the RMI inter-agreement validity was only moderate or fair in premenopausal women. Conclusions: Our study confirms the effectiveness of RMI algorithms in postmenopausal women. However, more sensitive tests are needed for premenopausal women.

The reactive oxygen species-total antioxidant capacity score is a new measure of oxidative stress to predict male infertility

  • Sharma, Rakesh K.;Pasqualotto, Fabio F.;Nelson, David R.;Thomas Jr, Anthony J.;Agarwal, Ashok
    • 대한생식의학회:학술대회논문집
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    • 대한불임학회 2000년도 제39차 춘계 학술대회
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    • pp.29-35
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    • 2000
  • The imbalance between reactive oxygen species (ROS) production and total antioxidant capacity (TAC) in seminal fluid indicates oxidative stress and is correlated with male infertility. A composite ROS-TAC score may be more strongly correlated with infertility than ROS or TAC alone. We measured ROS, TAC, and ROS-TAC scores in semen from 127 patients and 24 healthy controls. Of the patients, 56 had varicocele, eight had varicocele with prostatitis, 35 had vasectomy reversals, and 28 had Idiopathic infertility. ROS levels were higher among infertile men, especially those with varicocele with prostatitis (mean ${\pm}$ SE, 3.25 ${\pm}$ 0.89) and vasectomy reversals (2.65 ${\pm}$ 1.01). All infertility groups had significantly lower ROS-TAC scores than control. ROS-TAC score identified 80% of patients and was significantly better than ROS at identifying varicocele and idiopathic infertility. The 13 patients whose partners later achieved pregnancies had a mean ROS-TAC score of 47.7 ${\pm}$ 13.2, similar to controls but significantly higher than the 39 patients who remained infertile (35.8 ${\pm}$ 15.0; P < 0.01). ROS-TAC score is a novel measure of oxidative stress and Is superior to ROS or TAC alone in discriminating between fertile and infertile men. Infertile men with male factor or idiopathic diagnoses had significantly lower ROS-TAC scores than controls, and men with male factor diagnoses that eventually were able to initiate a successful pregnancy had significantly higher ROS-TAC scores than those who failed.

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