• Proceedings of KOSOMES biannual meeting
• /
• 2017.04a
• /
• pp.47-48
• /
• 2017

• Proceedings of the Korean Institute of Navigation and Port Research Conference
• /
• 2007.12a
• /
• pp.283-286
• /
• 2007

최근 우리나라 여러 주요 항만에 해상교량의 건설이 진행 중이거나 계획 중에 있는데, 이들 교량의 설치 위치나 규모가 주로 경제적인 측면만을 강조하여 이루어짐으로써, 선박 동항안전에 위협을 주고 있으며, 이해 당사자 간의 갈등이 고조되고 있는 현실이다. 따라서 이 연구에서는 선박 통항로 상에 많은 해상교량을 가지고 있는 미국의 해상교량 관련 법령과 절차를 조사${\cdot}$연구하여 우리나라의 제도를 제안하는데 참조하고자 한다.

• Transactions of the Korean Society of Mechanical Engineers
• /
• v.18 no.12
• /
• pp.3357-3368
• /
• 1994

Total pressure losses required to calculate the total-to-total efficiency are estimated by integrating empirical loss coefficients of four loss mechanisms along the mean-line of blades as follows; blade profile loss, secondary flow loss, end wall loss and tip clearance loss. The off-design points are obtained on the basis of Howell's off-design performance of a compressor cascade. Also, inlet-outlet air angles and camber angle are obtained from semi-empirical relations of transonic airfoils' minimum loss incidence and deviation angles. And nominal point is replaced by the design point. It is concluded that relatively simple loss models and Howell's off-design data permit us to calculate the off-design performance with satisfactory accuracy. And this method can be easily extended for off-design performance prediction of multi-stage compressors.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
• /
• 2007.12a
• /
• pp.287-289
• /
• 2007

최근 우리나라 여러 주요 항만에 해상교량의 건설이 진행 중이거나 계획 중에 있는데, 이들 교량의 설치 위치나 규모가 주로 경제적인 측면만을 강조하여 이루어짐으로써, 선박 통항안전에 위협을 주고 있으며, 이해 당사자 간의 갈등이 고조되고 있는 현실이다. 이에 본 연구에서는 국내 해상교량 관련 법령과 절차에 대한 조사 및 연구를 통하여 현행 제도에 대한 문제점을 파악해 보고자 한다.

• Journal of Aerospace System Engineering
• /
• v.8 no.2
• /
• pp.27-32
• /
• 2014

From the flight safety and the performance point of views, a new engine installation impacts an helicopter development or upgrade program significantly. More than a close relationship between an aircraft manufacturer and an engine manufacturer is necessary for the best integration work from the program initiation phase. In this paper, technical cooperation between aircraft and engine companies, and technical supports by the engine manufacturer for the T700/701K engine during the Surion development program are summarized. The applications of official technical program documents, US Mil-spec, France airworthiness regulations as the standard of the engine installation work, and engineering activities at each phase such as contract, design and manufacturing, flight clearance, ground and flight tests are described. This paper would be a cornerstone for the future domestic helicopter development program.

• Journal of Life Science
• /
• v.17 no.11
• /
• pp.1497-1504
• /
• 2007

To investigate the function and secretion of human thrombopoietin (TPO) in mammalian cells, hTPO cDNA was cloned using human liver cDNA, and recombinant hTPO (rec-hTPO) was produced in CHO cell lines. In addition, six N-linked glycosylation sites were substituted for Ala to elucidate the role of each carbohydrate chain. To analyze the biological activity, rec-hTPO protein was injected subcutaneously. Blood was withdrawn for platelet determination. The metabolic clearance rate (MCR) was also analyzed at the 1, 4, 10 and 24 hr after tail vein injection. Wild-type TPO (WT) was efficiently secreted into the medium. However, a hTPO mutant with 116 deleted nucleotides detected by PCR cloning was not secreted. The N-linked glycosylation sites had nearly the same expression quantity as rec-hTPO WT apart from mutants 3 and 4. The glycosylation site of mutant 4 appeared to be an indispensable site for hTPO secretion. Also characterized was the biological activity through an injection with rec-hTPO (10 ng) to ICR mice (7 weeks). The result of the blood analysis showed a considerable increase in the platelet number six days after He injection. To analyze the pharmacokinetics, rec-hTPO was injected into the tail vein (5 ng). The result was 200 pg/ml 1hr after this injection. Following this, it dramatically decreased and virtually disappeared 10 hours after the injection. Thus, rec-hTPO may be a treatment for thrombopenia by the production of the high active rec-hTPO. In addition, hTPO can permit the development of potent new analogues that stimulate the platelet value.