• The Journal of Korean Medicine
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• v.35 no.4
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• pp.36-51
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• 2014

Objectives: cDNA microarray is an effective method to snapshot gene expression. Functional clustering of gene expressions can identify herbal medicine mechanisms. Much microarray data is available for various herbal medicines. This study compares regulated genes with herbal medicines to evaluate the nature of the drugs. Methods: Published microarray data were collected. Total RNAs were prepared from dissociated hippocampal dissociate cultures which were given hypoxic shock in the presence of each herbal medicine. Up- or downregulated genes higher than Global M value 0.5 were selected, clustered in functional groups, and compared with various herbal treatments. Results: 1. Akt2 was upregulated by Acorus gramineus SOLAND, Arisaema amurense var. serratum $N_{AKAI}$ and Coptis chinensis $F_{RANCH}$, and they belong to Araceae herb. 2. Nf-${\kappa}b1$, Cd5, $Gn{\gamma}7$ and Sgne1 were upregulated by Arisaema amurense var. serratum $N_{AKAI}$, Coptis chinensis $F_{RANCH}$ and Rheum coreanum $N_{AKAI}$. 3. Woohwangcheongsim-won, Sohaphyang-won and Scutellaria baicalensis $G_{EORGI}$ downregulated Scp2 and upregulated Tsc2. Woohwangcheongsim-won and Sohaphyang-won upregulated Hba1 and downregulated Myf6. 4. Sohaphyang-won and Scutellaria baicalensis $G_{EORGI}$ downregulated Slc12a1. 5. Woohwangcheongsim-won and Arisaema amurense var. serratum $N_{AKAI}$ upregulated $Rar{\alpha}$, Woohwangcheongsim-won and Coptis chinensis $F_{RANCH}$ downregulated Rab5a and $Pdgfr{\alpha}$, and Woohwangcheongsim-won and Rheum coreanum $N_{AKAI}$ upregulated $Plc{\gamma}1$ and downregulated Pla2g1b and Slc10a1. Conclusions: By clustering microarray, genes are commonly identified to be either up- or downregulated. These results will provide new information to understand the efficacy of herbal medicines and to classify them at the molecular level.

• Fashion & Textile Research Journal
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• v.19 no.6
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• pp.786-794
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• 2017

The purpose of this study is to analyze and classify breast shape of women aged 11~15 using 3D body scan data. In this study, 250 women's body scans were selected from the 6th Size Korea dataset, and 30 items from each of the scan were measured using RapidForm XOR 3 program. The principal component analysis and cluster analysis were conducted using statistical program SPSS 17.0. The five principal components were identified; breast drooping and breast capacity, size from chest to under bust area, breast protrusion, breast height, and under breast angle & outer distance of breast. As the results of cluster analysis, woman's breast types were classified into four types. The breast type 1 was protrusion type (25.1%) which is considered as the breast maturity stage. The breast type 2 had the most drooped breast covering a large area (20.2%). The breast type 3 had the least prominent breast with a highest nipple point, which was considered as the early breast development stage (38.9%). The breast type 4 had the obesity of the chest and breast circumferences with the slightly prominent and the least drooped breast (15.8%). This study can provide fundamental information to develop sizing system and brassiere pattern for junior girls.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.38 no.5
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• pp.576-582
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• 2001

The Multi-Band Excitation(MBE) speech coder uses a different approach for the representation of the excitation signal. It replaces the frame-based single voiced/unvoiced classification of a classical speech coder with a set of such decision over harmonic intervals in the frequency domain. This enables each speech segment to be a mixture of voiced and unvoiced, and improves the synthetic speech quality by reducing decision errors that might occur on the frame-based single voiced and unvoiced decision process when input speech is degraded with noise. The IMBE-LP, improved version of MBE with linear prediction, represents the spectral information of MBE model with linear prediction coefficients to obtain low bit rate of 2.4 kbps. In this Paper, we proposed a variable rate IMBE-LP vocoder that has lower bit rate than IMBE-LP without degrading the synthetic speech quality. To determine the LP order, it uses the spectral band information of the MBE model that has something to do with he input speech's characteristics. Experimental results are riven with our findings and discussions.

• Resources Recycling
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• v.10 no.3
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• pp.14-22
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• 2001

For the recycle of coal fly ash generated from power stations, we developed an electrocyclone system which can separate unburned carbon form coal fly ash, based on the fact that coarse fly ash particles contain higher amount of unburned carbon and unburned carbon particles are charged positively, and pure ash particles are charged negatively on contacting each other. Additionally, guide vanes were installed in the cyclone to control the cut size. Two types of electrode, stick and grid type, were designed to investigate the effect of electrode type. Results show that by introducing an electric field inside the cyclone, the yield increases by 5 to 15e1o. But the content of unburned carbon in the clean ash does not change significantly.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.36 no.6
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• pp.273-279
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• 2014

Purpose: This study assessed the association between eye symptoms (enophthalmos or diplopia) and site of damage, volume, deviated inferior rectus muscle (IRM) and type of fracture with computed tomography (CT). The intent is to anticipate the prognosis of orbital trauma at initial diagnosis. Methods: Forty-five patients were diagnosed with fractures of the inferior wall of one orbit. Fracture area, volume of displaced tissue, deviated IRM, and type of fracture were evaluated from coronal CT by one investigator. The association of those variables with the occurrence of eye symptoms (diplopia and enophthalmos) was assessed. Results: Of 45 patients, 27 were symptom-free (Group A) and 18 had symptoms (Group B) of enophthalmos and/or diplopia. In Group B, 12 had diplopia, one was enophthalmos, and five had both. By CT measurement, group A mean area was $192.6mm^2$ and the mean volume was $673.2mm^3$. Group B area was $316.2mm^2$ and volume was $1,710.6mm^3$. The volume was more influential on symptom occurrence. Each patient was categorized into four grades depending on the location of IRM. Symptom occurrence and higher grade were associated. Twenty-six patients had trap-door fracture (one side, attached to the fracture), and 19 had punched-out fracture (both sides detached). The punched-out fracture was more strongly associated with symptoms and had statistically significantly higher area and volume. Conclusion: In orbital trauma, measurement of fracture area and volume, evaluation of the deviated IRM and classification of the fracture type by coronal CT can effectively predict prognosis and surgical indication.

• Development and Reproduction
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• v.17 no.3
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• pp.199-205
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• 2013

Genomic DNAs were extracted from the turtle leg (Pollicipes mitella, 1798) population of Tongyeong, Yeosu and Manjaedo located in the southern sea of Korea. The turtle leg population from Tongyeong (0.929) exhibited higher bandsharing values than did turtle leg from Manjaedo (0.852). The higher fragment sizes (>1,200 bp) are much more observed in the Yeosu population. The number of unique loci to each population and number of shared loci by the three populations, generated by PCR using 7 primers in the turtle leg (P. mitella) population of Tongyeong, Yeosu and Manjaedo. Genetic distances among different individuals of the Tongyeong population of the turtle leg (lane 1-07), Yeosu population of the turtle leg (lane 08-14) and Manjaedo population of the turtle leg (lane 15-21), respectively, were generated using the CLASSIFICATION option in Systat version 10 according to the bandsharing values and similarity matrix. The dendrogram, obtained by the seven decamer primers, indicated three genetic clusters: cluster 1 (TONGYEONG 01 TONGYEONG 07), cluster 2 (YEOSU 08 YEOSU 14), and cluster 3 (MANJEDO 15 MANJEDO 21). Tongyeong population could be evidently discriminated with the other two Yeosu and Manjaedo populations among three populations. The longest genetic distance (0.305) was found to exist between individuals' no. 02 of the Tongyeong population and no. 13 of the Yeosu population. It seems to the authors that this is a result of a high degree of inbreeding in narrow region for a long while.

• Journal of the Korean Society of Clothing and Textiles
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• v.25 no.4
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• pp.795-806
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• 2001

This study is to classify the somatotypes of middle-aged women by many critera and figure out he characteristics of each somatotypes. The subjects are 614 middle-aged women between 35 and 59 years old and the research is based on anthropometric and photometric measurement by photographing their body parts. The results are as follows; 1. The result of factor analysis indicated that 11 factors were extracted through factor analysis and orthogonal rotation by the method of varimax and those factors comprised 85.71 percent of total variance. 2. As the result of cluster analysis the group of the middle-aged women is classified as 6 types. Type 1 is short, fat, H type in front and lean-back type on the side. Type 2 is standard in height and weight. Type 3 is standard height, fat, long upper body, bend-forward type and protrude of the hip on the side. Type 4 is tall, thin, short upper body, having clearly protrude of the back and hip and lean-back type on the side. Type 5 is neither short nor tall, slim, X type in front and I type on the side. Type 6 is tall, thin and B type on the side. 3. As the result of observing the mutual corresponding relation between these 6 groups and age/Rohrers Index, the somatotype of the middle-aged women is divided at the age of 45. Accordingly when it comes to progress the study of the middle-aged women in the future, we will have to observe the characteristics for dividing the first half and the second half of age of 45.

• Korean Journal of Biological Psychiatry
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• v.13 no.3
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• pp.170-177
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• 2006

Objectives : Disturbances of serotonergic system might be related to the possible mechanism of social phobia. This study was to investigate the association of serotonin transporter gene and social phobia. Methods : Sixty nine patients with social phobia(51 male(73.9%), mean age $35.17{\pm}11.89$ years) and seventy four normal controls(54 male(73.0%), mean age $33.46{\pm}9.63$ years) were tested for serotonin transporter gene-linked polymorphic region(5-HTTLPR) polymorphism. Additionally, patients were grouped into 46 generalized(GEN) and 23 nongeneralized(NGEN) subgroups and 5-HTTLPR polymorphism was compared with that of normal controls. The genotypes and allele frequencies of the 5-HTTLPR polymorphism between social phobia and the control group were compared. Genomic DNA was extracted from their blood and 5-HTTLPR polymorphisms were determined by using polymerase chain reaction. Results : Significant association was observed between the S(ss) genotype and social phobia, by functional classification(p=.010). In allele frequency analysis, a significant association was also observed between the short allele and social phobia(p=.030). A significant associations between S genotype and each subgroup were observed(GEN p=.045 ; NGEN p=.033), but there were no differences in allele frequency. And, no differences in genotype and allele distribution between two subgroups were found. Conclusion : The results in our Korean sample suggest that S genotype of 5-HTTLPR may be associated with social phobia and s allele may be an important genetic factor that activates social phobic symptoms. But, further studies including large number of samples are necessary to elucidate these present findings.

• Journal of Pharmacopuncture
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• v.13 no.4
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• pp.139-147
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• 2010

Objectives : The Purpose of this study is to investigate and report the effectiveness of Hominis Placenta using Pharmacopuncture treatment for trigger finger. Methods : 3 Patients are admitted at Dept. of Oriental Rehabilitation, Bu-Chun Jaseng Oriental Medicine Hospital, diagnosed as Trigger finger and treated with Hominis Placenta Pharmacopuncture. Each cases are measured and assessed by Quinnell's classification of triggering and VAS (Visual Analogue Scale) scores. Results : 3 Patients of trigger finger have a different kind of cause and fingers lesion they have, but nodules are not significantly found up, so we could classify all of 3 patients to diffuse type. After treatment of Hominis placenta Pharmacopuncture, spontaneous pain and tenderness, grades of triggering are decreased significantly. We would expect that Hominis placenta Pharmacopuncture has a effect on degenerative diseases of diffuse type's tendon sheath. Conclusions : Trigger finger is generally divided into two stages, inflammatory and degenerative stage, and when degenerative stage, Hominis placenta pharmacopuncture appears to be effective.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• autumn
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• pp.525-528
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• 2003

In recent, Information Technology(IT) is the biggest issue on the world at large including construction industry as core strategic means for reinforcing competitive power of company and nation and raising its effectiveness. However, CEO of each finn is deferring IT investment decision because there's no case to measure real value of IT and confidence to economic effect of information system. IT Evaluation will be so helpful that most construction finns make a plan of IT investment. and it is necessary to achieve their management goal and have the maximum of firm's value with the usage of IT system. Therefore, The purpose of this research is to promote the increase of IT investment and the improvement of the standard in IT with the development of IT evaluation system to be monitoring IT level continually.