• Mycobiology
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• v.38 no.3
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• pp.215-218
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• 2010

Azoles are currently the most widely used class of antifungal drugs clinically, and are effective for treating fungal infections. Target site of azoles is ergosterol biosynthesis in fungal cell membrane, which is absent in the mammalian host. However, the development of resistance to azole treatments in the fungal pathogen has become a significant challenge. Here, we report the identification and functional characterization of a UPC2 homolog in the human pathogen Cryptococcus neoformans. UPC2 plays roles in ergosterol biosynthesis, which is also affected by the availability of iron in Saccharomyces cerevisiae and Candida albicans. C. neoformans mutants lacking UPC2 were constructed, and a number of phenotypic characteristics, including antifungal susceptibility and iron utilization, were analyzed. No differences were found between the mutant phenotypes and wild type, suggesting that the role of C. neoformans UPC2 homolog may be different from those in S. cerevisiae and C. albicans, and that the gene may have a yet unknown function.

• Korean Management Science Review
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• v.11 no.3
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• pp.1-11
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• 1994

Recent advances in linear programming solution methodology have focused on interior point methods. This powerful new class of methods achieves significant reductions in computer time for large linear programs and solves problems significantly larger than previously possible. These methods can be examined from points of Fiacco and McCormick's barrier method, Lagrangian duality, Newton's method, and others. This study presents a primal-dual log barrier algorithm of interior point methods for linear programming. The primal-dual log barrier method is currently the most efficient and successful variant of interior point methods. This paper also addresses a Cholesky factorization method of symmetric positive definite matrices arising in interior point methods. A special structure of the matrices, called supernode, is exploited to use computational techniques such as direct addressing and loop-unrolling. Two dense matrix handling techniques are also presented to handle dense columns of the original matrix A. The two techniques may minimize storage requirement for factor matrix L and a smaller number of arithmetic operations in the matrix L computation.

• Journal of Institute of Control, Robotics and Systems
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• v.8 no.4
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• pp.299-302
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• 2002

Error detection and correction using CRC and the general class of cyclic codes is an important part of designing reliable data transmission schemes. The decoding method for cyclic codes using covering patterns is easily-implementable, and its complexity de-pends on the number of covering patterns employed. Determination of the minimal set of covering patterns for a given code is an open problem. In this paper, an efficient search method for constructing minimal sets of covering patterns is proposed and compared with several existing search methods. The result is applicable to various codes of practical interest.

• Transactions on Electrical and Electronic Materials
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• v.15 no.4
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• pp.201-206
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• 2014

LED lighting,considered to be a new growth industry, has attracted a great deal of attention due to its higher illumination and longer life time than existing light sources. In this study, high-efficiency and long-life LED fog lamps for automobiles were developed, which can substitute the existing 27 W halogen fog lamps for a used car market. For this purpose, the number of LED modules, the body, heat sink, and the output of the fog lamp were first optimized through a numerical analysis. Then, a 10 W-class LED fog lamp was prototyped based on the optimized numerical model, and the performance of the fog lamp was successfully verified through the experiments.

• Journal of the Korean Institute of Educational Facilities
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• v.2 no.2
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• pp.41-50
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• 1995

The large increase in the number of students and the current rapid social change requires the expansion of educational facilities for the improvement of the educational content and its method, the usefulness of educational media, and the improvement of teaching and learning activities. The educational facilities have largely served is done efficiently and it results in a functional harmony of these two aspects. In order to maximize this harmony, and thus maximize the efficiency of school education, we must analyze the human engineering factors of educational facilities through human being that is the main subject of education, humans. Therefore to maximize the efficiency of school education, we must analyze the human engineering factors of educational facilities through human being that is the main subject in learning and living. In Conclusion we suggest the following six analying standards on human engineering of educational facilities; 1. adequacy 2. suitability 3. healthfulness 4. safety 5. beauty 6. modernity.

• Proceedings of the KIEE Conference
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• 2004.10a
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• pp.143-146
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• 2004

This is a thesis that 100W class open frame type power module of a quarter-brick size appropriate for telecommunication is reported. The input voltage is established between 36 and 75 in range in order for power module to be utilized for the telecommunication, and output were set at 3.3V and 30A. A number of parts used for transformer, inductor, and hit sink are composed of PCB in order for DC-DC converter to be lowered below 8 mm. A constant current control circuit was annexed to the system as well as basic protection prototypes such as over-voltage, over-current, and over-temperature were well considered to enhance more credibility, and were tested. As a result, high circuit performance and credibility turned out to be significant.

• MALSORI
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• no.44
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• pp.105-113
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• 2002

In Korean, each digit is monosyllable and some pairs are known to have high confusability, causing performance degradation of connected digit recognition systems. To improve the performance, in this paper, we employ various discriminant analyses (DA) including Linear DA (LDA), Weighted Pairwise Scatter LDA WPS-LDA), Heteroscedastic Discriminant Analysis (HDA), and Maximum Likelihood Linear Transformation (MLLT). We also examine several combinations of various DA for additional performance improvement. Experimental results show that applying any DA mentioned above improves the string accuracy, but the amount of improvement of each DA method varies according to the model complexity or number of mixtures per state. Especially, more than 20% of string error reduction is achieved by applying MLLT after WPS-LDA, compared with the baseline system, when class level of DA is defined as a tied state and 1 mixture per state is used.

• The Korean Journal of Applied Statistics
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• v.15 no.2
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• pp.367-379
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• 2002

In this paper, the method of constructing incomplete block designs for comparing general combining abilities of p inbred lines for partial diallel crosses is proposed. These partial diallel crosses block designs are constructed by using m-associate class partially balanced incomplete block designs with block size 2 and balanced incomplete block designs. Also, the efficiencies of block designs obtained through this method are tabulated for number of lines 24 or less.

• Journal of applied mathematics & informatics
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• v.28 no.1_2
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• pp.209-216
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• 2010

A spectrally arbitrary complex sign pattern A is a complex sign pattern of order n such that for every monic nth degree polynomial f(x) with coefficients from $\mathbb{C}$, there is a matrix in the qualitative class of A having the characteristic polynomial f(x). In this paper, we show a necessary condition for a spectrally arbitrary complex sign pattern and introduce a minimal spectrally arbitrary complex sign pattern $A_n$ all of whose superpatterns are also spectrally arbitrary for $n\;{\geq}\;2$. Furthermore, we study the minimum number of nonzero parts in a spectrally arbitrary complex sign pattern.

• Journal of Advanced Marine Engineering and Technology
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• v.25 no.6
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• pp.1211-1219
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• 2001

The electro-rheological(ER) fluids for smart hydraulic system are a class of colloidal dispersion which exhibit large reversible Changes in their rheological behavior when they are subjected to external electrical fields. This paper presents experimental results on material properties of an ER fluids subjected to electrical fatigues. As a first step, ER fluid is made of methyl cellulose(MC) choosing 25% of particle weight-concentration. Following the construction of test mechanism for durability estimation, the dynamic yield shear stress and the current density for the ER fluids of MC component are experimentally distilled as a function of electric field. In addition, the surface roughness of the employed electrode are evaluated as a function of the number of the electric-field cycles.