• 대한한방내과학회지
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• 제44권6호
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• pp.1176-1185
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• 2023

Introduction: Non-erosive reflux disease (NERD) is the most common subtype of gastroesophageal reflux disease (GERD). This study aims to synthesize evidence on the efficacy and safety of various herbal medicines for the treatment of NERD. Methods and analysis: Ten electronic databases will be examined: MEDLINE (via PubMed), Cochrane Central Register of Controlled Trials, Embase, Allied and Complementary Medicine Database, China National Knowledge Infrastructure Database, Citation Information by Nii, Korean Medical Database, Korean Studies Information Service System, National Digital Science Library, and Oriental Medicine Advanced Searching Integrated System. All randomized controlled trials published from inception to May 2023 that meet the eligibility criteria will be selected. Two independent researchers will extract data, such as publication year, study design, intervention details, outcome measures, main results, and adverse events. The risk of bias and quality of evidence will be assessed, and subgroup analyses will be performed according to the type of control intervention and herbal medicine. The analysis process will be conducted using Review Manager 5.4 software. Discussion: This review will present a summary and rationale for herbal medicine's effectiveness in treating NERD. The findings of this review can help those who want to apply herbal medicine to the treatment of NERD.

• 정보관리학회지
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• 제29권4호
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• pp.143-163
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• 2012

현재 국내외 대학도서관의 전자학술정보 입수는 일명 빅딜로 불리는 수백, 수천 종의 전자학술지 묶음을 다년간, 고정된 인상율로 계약하는 구독방식이 주류를 이루고 있다. 1990년대 중반에 시작된 이러한 구독방식은 대학도서관과 이용자에게 많은 장점을 제공했다. 하지만 이들 패키지의 가격이 지속적으로 상승함에 따라 이러한 방식의 지속가능성에 대한 의문이 제기되고 있다. 현재까지 pay-per-view 방식을 제외하면 구독기반 모형의 구체적인 대안은 제시되지 않고 있으며 향후 도서관 예산문제가 심각한 뇌관으로 남아있다. 2000년대 초반 시작된 오픈액세스 운동은 다양한 방법으로 학술지의 출판과 유통의 장벽을 제거하고 있다. 오픈액세스 출판 규모는 매년 두 자릿수로 증가하고 있고, 오픈액세스 학술지 논문은 Scopus와 Web of Science 인용데이터베이스에의 편입비율이 20%에 육박하는 등 양적, 질적인 성장을 보이고 있다. 2004년에 시작된 구글 학술검색은 현재 대다수 학술출판사의 학술지 논문에 대한 편리한 검색 및 접근 도구로 성장하고 있다. 비록 학술지 선택의 기준, 제한된 검색 기능, 독점화에 대한 우려 등이 있지만 구글 학술검색을 대학도서관 데이터베이스의 대안으로 진지하게 주목할 필요가 있다. 대학도서관의 예산 문제, 오픈액세스 출판의 활성화, 구글 학술검색과 같은 무료 도구의 성장은 구독기반 모형을 대체할 수 있는 파괴적인 변화로 인식되고 있으며 대학도서관 사서는 새로운 환경에 대한 구체적인 대응을 고민해야 한다.

• 정보관리학회지
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• 제17권1호
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• pp.49-65
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• 2000

본 연구에서는 대한 의학학술지 편집인협의회가 1997년 11월부터 1999년 11월까지 7차에 걸쳐 평가한 한국 의학학술지 82종의 평가결과 중에서 서지정보를 이용한 평가항목의 데이터를 분석하여 한국 의학학술지의 국내외 이용도 (인용도)및 이용가능성을 측정하였다. 한국 의학학술지는 국내 의학도서관의 약 절반 정도에만 소장되어 있으며, DIALOG에서 검색 가능한 의학 및 의학관련 색인ㆍ초록 데이터베이스 36종에 등재되고 있는 것은 10종 (12.2%)뿐이다. 자체학술지 인용도는 3.402%이며, 1.092%의 논문만이 출판된지 3년 이내에 SCISearch에 1회 이상 인용되었을 뿐이다. 한국 의학학술지의 평균영향력지표는 0.011이다. 그러나, MEDLINE이나 SCISearch에 등재되고 있는 학술지의 영향력지표는 10배정도 높은 것으로 나타났다. 이와 같이, 국내 의학학술지에 발표된 한국 의학논문들은 그 존재가 국내외적으로 알려지고 이용될 가능성이 원천적으로 봉쇄되어 있는 실정이며, 같은 분야의 동료 한국학자들에 의해서도 별로 인용되지 못하고 있으며, 특히 SCISearch 학술지에 게재된 논문들에 의해서는 거의 인용되지 못하고 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권23호
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• pp.10421-10425
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• 2015

Background: While the incidence of non-Hodgkins lymphoma (NHL) has been rising worldwide, the reasons remain undefined. Recent research has focused on effect of red andf processed meat intake as a risk factor, but with inconclusive results. We therefore conducted a meta-analysis of data published to date, to ascertain the overall association between intake and NHL. Materials and Methods: A published literature search was performed through Pubmed, Cochrane Library, Medline, and Science Citation Index Expanded databases for articles published in English. Pooled odds ratios (ORs) and 95% confidence intervals (95%CIs) were calculated using random or fixed effects models. Heterogeneity was assessed using Chi-square and I2 statistics. Dissemination bias was evaluated by funnel plot analysis.We performed a formal meta-analysis using summary measures from these studies. Results: In total, 11 published studies were included in the final analysis. The combined analysis revealed that there was significant association between the red meat and NHL risk (OR=1.10, 95%CI: 1.02 to 1.19, p=0.01). Additionally, there was showed significance association between processed red meat and NHL risk (OR=1.17, 95%CI: 1.06 to 1.29, p=0.001). In subgroup analysis, a statistical significant association was noted between diffuse large B-cell lymphoma (DLBCL) (OR=1.20, 95%CI: 1.04 to 2.37, P=0.01) and red meat intake. Conclusions: In this meta-Analysis, there was evidence for association between consumption of red meat, or processed meat and risk of NHL, particularly with the DLBCL subtype in the red meat case.

• Asian Pacific Journal of Cancer Prevention
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• 제15권3호
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• pp.1263-1267
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• 2014

Background: Matrix metalloproteinases (MMPs) play important roles in pathogenesis and development of cancer. Recently, many studies have show associations between polymorphisms in the promoter regions of MMPs and risk of gastric cancer. The present meta-analysis was conducted in order to investigate the potential association between four polymorphisms in the MMP gene and gastric cancer risk. Methods: A computerized literature search was conducted in databases of Med-line, Embase, Science Citation Index and PubMed till June 2013 for any MMP genetic association study of gastric cancer. Odds ratios (ORs) and 95 % confidence intervals (CIs) were estimated for each gene under dominant and recessive models, and heterogeneity between studies was assessed using the Q test and $I^2$ value. Overall and subgroup analyses according to ethnicity were carried out with Stata 12.0. Results: 14 reports covering 8,146 patients (2,980 in the case group and 5,166 in the control group) were included in the present meta-analysis. We found that the MMP-7 (-181A>G) polymorphism increased the gastric cancer risk in therecessive model (GG vs. AA/AG, OR=1.768, 95% CI =1.153-2.712). For MMP2 -1306 C>T, MMP1-1607 1G/2G, and MMP9-1 562 C>T, there were no associations between these polymorphisms and the risk of gastric cancer under dominant or recessive models. Conclusion: This meta-analysis suggested that the MMP7-181 A>G polymorphism may contribute to gastric cancer susceptibility. More studies are needed, especially in Europeans, in the future.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7847-7852
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• 2015

Purpose: Research carried out with gynecologic cancer patients using CAM was reviewed to provide a source for discussing which CAM method is used for which purpose, patients' perceptions on the effects/side effects occurred during/after using CAM and their sources of information regarding CAM. Materials and Methods: This literature review was carried out for the period between January 2000 and March 2015 using Scopus, Dynamed, Med-Line, Science Dırect, Ulakbim, Research Starters, Ebscohost, Cinahl Complete, Academic Onefile, Directory of Open Access Journals, BMJ Online Journals (2007-2009), Ovid, Oxford Journal, Proquest Hospital Collection, Springer-Kluwer Link, Taylor & Francis, Up To Date, Web Of Science (Citation Index), Wiley Cochrane-Evidence Base, Wiley Online Library, and Pub-Med search databases with "complementary and alternative medicine, gynecologic cancer" as keywords. After searching through these results, a total of 12 full length papers in English were included. Results: CAM use in gynecologic cancer patients was discussed in 8 studies and CAM use in breast and gynecologic cancer patients in 4. It was determined that the frequency of CAM use varies between 40.3% and 94.7%. As the CAM method, herbal medicines, vitamins/minerals were used most frequently in 8 of the studies. When the reasons why gynecologic cancer patients use CAM are examined, it is determined that they generally use to strengthen the immune system, reduce the side effects of cancer treatment and for physical and psychological relaxation. In this review, most of the gynecologic cancer patients perceived use of CAM as beneficial. Conclusions: In order that the patients obtain adequate reliable information about CAM and avoid practices which may harm the efficiency of medical treatment, it is recommended that "Healthcare Professionals" develop a common language.

• Asian Pacific Journal of Cancer Prevention
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• 제15권4호
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• pp.1803-1806
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• 2014

Endoscopic submucosal dissection (ESD) was originally developed for en bloc resection of large, flat gastrointestinal lesions. Compared with endoscopic mucosal resection (EMR), ESD is considered to be more time consuming and have more complications for treatment of early esophageal carcinoma, such as bleeding, stenosis and perforation. The objective of this study was to compare the efficacy and safety of ESD and EMR for such lesions. We searched databases, such as PubMed, EMBASE, Cochrane Library and Science Citation Index updated to 2013 for related trials. In the meta-analysis, the main outcome measurements were the en bloc resection rate, the histologically resection rate and the local recurrence rate. We also compared the operation time and the incidences of procedure-related complications. Five trials were identified, and a total of 710 patients and 795 lesions were included. The en bloc and histologically complete resection rates were higher in the ESD group compared with the EMR group (odds ratio (OR) 27.3; 95% CI, 11.5-64.8; OR 18.4; 95% CI, 8.82-38.59). The local recurrence rate was lower in the ESD group (OR 0.13, 95 % CI 0.04-0.43). The meta-analysis also showed ESD was more time consuming, but did not increase the complication rate (P=0.76). The results implied that compared with EMR, ESD showed better en bloc and histologically resection rates, and lower local recurrence, without increasing the incidence of procedure-related complications in the treatment of early esophageal carcinoma.

• Asian Pacific Journal of Cancer Prevention
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• 제15권18호
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• pp.7625-7628
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• 2014

Breast cancer is the most common cancer among women worldwide. The primary aim of this work was to provide an in-depth evaluation of research publications in the field of diets and breast cancer. The impact of economic outcome on national academic productivity was also investigated. Data were retrieved using Pubmed for English-language publications. The search included all research for which articles included words relating to "diets and breast cancer". Population and national income data were obtained from publicly available databases. Impact factors for journals were obtained from Journal Citation Reports$^{(R)}$ (Thomson Scientific). There were 2,396 publications from 60 countries in 384 journals with an impact factor. Among them, 1,652 (68.94%) publications were Original articles. The United States had the highest quantity (51% of total) and highest of mean impact factor (8.852) for publication. Sweden had the highest productivity of publication when adjusted for number of population (6 publications per million population). Publications from the Asian nation increased from 5.3% in 2006 to 14.6% in 2012. The Original article type was also associated with geography (p<0.001; OR=2.183; 95%CI=1.526-3.123), Asian countries produced more proportion of Original articles (82%) than those of rest of the world (67.6%). Diets and breast cancer-associated research output continues to increase annually worldwide including publications from Asian countries. Although the United States produced the most publications, European nations per capita were higher in publication output.

• Asian Pacific Journal of Cancer Prevention
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• 제16권3호
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• pp.1057-1062
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• 2015

Background: Since the survival rate of breast cancer patients has improved, harmful effects of new treatment modalities on fertility of the young breast cancer patients has become a focus of attention. This study aimed to systematically review and critically appraise all available guidelines for fertility preservation in young breast cancer patients. Materials and Methods: Major citation databases were searched for treatment guidelines. Experts from relevant disciplines appraised the available guidelines. The AGREE II Instrument that includes 23 criteria in seven domains (scope and purpose of the guidelines, stakeholder involvement, rigor of development, clarity, applicability, editorial independence, and overall quality) was used to apprise and score the guidelines. Results: The search strategy retrieved 2,606 citations; 72 were considered for full-text screening and seven guidelines were included in the study. There was variability in the scores assigned to different domains among the guidelines. ASCO (2013), with an overall score of 68.0%, had the highest score, and St Gallen, with an overall score of 24.7%, had the lowest scores among the guidelines. Conclusions: With the promising survival rate among breast cancer patients, more attention should be given to include specific fertility preservation recommendations for young breast cancer patients.

• 동의생리병리학회지
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• 제25권4호
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• pp.721-727
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• 2011

The purpose of this study was to review the current situation of Sasang typology studies and get a recommendation for ameliorating it by systematically reviewing articles published in Korea from 2000 to 2009. Six hundred seventy-seven articles were found by searching the representative Korean databases such as KISS, RISS, KISTI, DBPIA, NDSL and also by hand search. Yearly analysis was performed by academic field, journal, author and affiliation, type of article and content. The analysis showed that the number of published articles has increased from 61 in 2000 to 86 in 2009. 607(89.6%) were related to medical field, 627(92.6%) were published in Korean Citation Index-listed journals, and 413(68.8%) were published in the Journal of Sasang Constitutional Medicine. The authors listed on one article were 3.98 persons and affiliated in 1.66 departments in average. Sixty six percents are for the clinical studies or case reports, and twenty-five for Sasang type diagnosis. This study showed that more active collaborations with diverse research fields and various research methods are needed for the improvement of Sasang typology studies and the scope expansion of Korean traditional medicine.