• Journal of the Institute of Electronics Engineers of Korea SC
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• v.44 no.5
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• pp.45-54
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• 2007

Time/frequency analysis has been extensively used in biomedical signal processing. By extracting some essential features from the electro-physiological signals, these methods are able to determine the clinical pathology mechanisms of some diseases. However, this method assumes that the signal should be stationary, which limits its application in non-stationary system. In this paper, we develop a new signal processing method using Hilbert-Huang Transform to perform analysis of the nonlinear and non-stationary ventricular fibrillation(VF). Hilbert-Huang Transform combines two major analytical theories: Empirical Mode Decomposition(EMD) and the Hilbert Transform. Hilbert-Huang Transform can be used to decompose natural data into independent Intrinsic Mode Functions using the theories of EMD. Furthermore, Hilbert-Huang Transform employs Hilbert Transform to determine instantaneous frequency and amplitude, and therefore can be used to accurately describe the local behavior of signals. This paper studied for Return Of Spontaneous Circulation(ROSC) and non-ROSC prediction performance by Support Vector Machine and three parameters(EMD-IF, EMD-FFT) extracted from ventricular fibrillation ECG waveform using Hilbert-Huang transform. On the average results of sensitivity and specificity were 87.35% and 76.88% respectively. Hilbert-Huang Transform shows that it enables us to predict the ROSC of VF more precisely.

• The Korean Journal of Pharmacology
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• v.23 no.2
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• pp.57-75
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• 1987

Two modalities of gonadotropin secretion, pulsatile gonadotropin and preovulatory gonadotropin surge, have been identified in the mammals. Pulsatile gonadotropin secretion is modulated by the pulsatile pattern of GnRH release and complex ovarian steroid feedback actions. The neural mechansim that regulates the pulsatile release of GnRH in the hypothalamus is called "GnRH pulse generator". Ovarian steroids, estradiol and progesterone, appear to exert thier feedback effects both directly on the pituitary to modulate gonadotropin release and on a hypothalamic site to modulate GnRH release; estradiol primarily affects the amplitude while progesterone decreases the frequency of the pulsatile GnRH. Steroid hormones are known to affect catecholamine transmission in brain. MBH-POA is richly innervated by NE systems and close apposition of NE terminals and GnRH cell bodies occurs in the MBH as well as in the POA. NE normally facilitates pulsatile LH release by acting through ${\alpha}-receptor$ mechanism. However, precise nature of facilitative role of NE transmission in maintaining pulsatile LH has not been clearly understood. Close apposition of DA and GnRH terminals in ME might permit DA to influence GnRH release. Action of DA transmission probably is mediated by axo-axonic contacts between GnRH and DA fibers in the ME. Dopamine transmission does not normally regulate pulsatile LH release, but under certain conditions, increased DA transmission inhibit LH pulse. Endogenous opioid acts to suppress the secretion of GnRH into hypophysial portal circulation, thereby inhibiting gonadotropin secretion. However, an interaction between endogenenous opioid peptides and gonadotropin release is a complex one which involves ovarian hormones as well. LH secretion appears to be most suppressed by endogenenous opioids during the luteal phase, at a time of elevated progesterone secretion. The arcuate nucleus contains not only cell bodies for GnRH and ${\beta}-endorphin$ but also a dense aborization of fibers suggesting that GnRH release is changed by the interactions between GnRH and ${\beta}-endorphin$ cell bodies within the arcuate nucleus. The frequency and amplitude of pulsatile LH release seem to be increased during the preovulatory gonadotropin surge. Estradiol exerts positive feedback action on the hypothalamo-pituitary axis to trigger preovulatory LH surge. GnRH is also crucial hormonal stimulus for preovulatory LH surge. It is unlikely, however, that increased secretion of GnRH during the preovulatory gonadotropin surge represents an obligatory neural signal for generation of the LH discharge in primates including human. Modulation of preovulatory LH surge by catecholamines has been studied almost exclusively in rats. NE and E may be involved in distinct way to accumulate GnRH in the MBH and its release into the hypophysial portal system during the critical period for LH surge on proestrus in rats. However, the mechanisms whereby augmented adrenergic transmission may facilitate the formation and accumulation of GnRH in the ME-ARC nerve terminals before the LH surge have not been clearly understood.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.10 no.1
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• pp.209-246
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• 1997

In the literatual study on the Ecthyma, the results were as follows. 1. The pathogenic factors of Ecthyma is divided three parts. One is exogenous pathogenic factors which including the wind evil, wind heat and toxic material produced by wetness evil. Another is endogenous pathogenic factors which including the declination of kidney-yang, impairment of the liver and kidney, the lower classes of yin-fire, accumulation of wetness-heat in the spleen asthenia, impairment of the liver and kidney, wetness-heat of three yang, asthenic heat-syndrome of three yin. The other is pathogenic factors neither endogenous nor exogenous which including the food and living, uncontrol sexual excess, anxiety and angry, injury of skin, injury of insects and animals. 2. Five viscera which was concerned with Ecthyma are liver, spleen and kidney. 3. Frequent region of Ecthyma are S-36(足三里) and C-7(陰交). External Ecthyma was rose to wetness-heat of three yang channel that cured easily. Internal Ecthyma was rose to asthenic heat-syndrome of three yin channel that cured hardly. 4. In the frequency of prescription, the most numerous prescription is Bojungikgitang(補中益氣湯) and the next are Kyukgigo(隔紙膏) and Yukmijihwanghwan(六味地滉丸). 5. In the frequency of medicine, the most medicine is Calomelas(輕粉) which included Hydrargyrum(水銀) and the next are Olibanum(乳香) and Resina Commiphorae Myrrhae(沒藥) which regulating vital energy and pain control medicine used that in order to destroy insects and remove polson. 6. In classification of the medical action, medicine of clearing away summer-heat and heat evil and activating blood circulation to dissipate blood stasis used to be very busy which in order to remove the disorder of vital energy for virulent heat-evil. 7. In classification of four characters, the most part is warm medicine, the next are cold and cool medicine and there is a few that is hot medicine. 8. In classification of five tastes, the most numerous tastes are bitter and acrid, the next are sweet, salty and sour tastes. 9. In classification of virulence of medicine, the most part is non-toxic, the next are weakly and deadly poison. 10. In classification of channel distribution, the most is the medicine that belongs to liver channel, the next are the lung, spleen, stomach and kidney channel.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.6
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• pp.390-395
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• 2019

Hydrogymnastics so that sufficient exercise effect can be obtained using the resistance of water has a positive effect on patients who have to receive arthritis or rehabilitation treatment. However, the studies on the effect are insufficient, and the main cause of their effects has not been unclear yet. In this study, in order to identify the main cause of the effects of Hydrogymnastics, conducted Unsteady fluid flow simulation under the same conditions as the actual environment. The analysis model based on real hands, and the pressure fluctuation applied to the knuckle was analyzed by the computational fluid method. During the underwater movement of the hands, Various sizes of vortices were generated between fingers due to skin surface velocity and flow resistance. Pressure of about -500 Pa to +500 Pa is applied by the vortex flow. Also It was confirmed that the positive pressure and the negative pressure were continuously repeated up to maximum + 2000 Pa at the minimum of -2000 Pa at the portion where the direction was changed. Pressure fluctuations with a frequency of 20 Hz to 70 Hz were added continuously for each knuckle. These continuous pressure fluctuations provide a direct massage effect on the knuckles, an It is judged that the blood circulation at the relevant part is positively affected.

• Journal of the Korean Society of Hazard Mitigation
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• v.9 no.6
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• pp.31-39
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• 2009

This study has found that there is a reverse phase with interdecadal variation in temporal variations of tropical cyclone (TC) genesis frequency (TCGF) between Northwest sector and Southeast sector, based on climatological mean tropical cyclone genesis location over the western North Pacific. The TCGF in the Northwest sector has been increased since the mid 1980s (1986-2005), while TCGF in the Southeast sector was higher until the early 1970s (1951-1970). The analysis of a difference between 1986-2005 and 1951-1970 showed results as follows: i) Through the analysis of vertical wind shear (VWS) and sea surface temperature (SST), less VWS and higher SST in the former (latter) period was located in the Northwest (Southeast) sector. ii) In the analysis of TC passage frequency (TCPF), TCs occurred in the Northwest sector frequently passed from east sea of the Philippines, through East China Sea, to Korea and Japan in the latter period, while TCs in the former period frequently has a lot of influences on South China Sea (SCS). In the case of TCs occurred in the Southeast sector, TCs in the west (east), based on $150^{\circ}E$ had a high passage frequency in the latter (former) period. In particular, TCs during the latter period frequently moved toward from the east sea of the Philippines to SCS and southern China. iii) This difference of TCPF between the two periods was characterized by 500 hPa anomalous pressure pattern. Particularly, anomalous cyclonic circulation strengthened over the East Asian continent caused anomalous southerlies along the East Asian coast line from the east sea of the Philippines to be predominate. These anomalous winds served as steering flows that TC can easily move toward same regions.

• Clinical and Experimental Pediatrics
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• v.46 no.10
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• pp.966-971
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• 2003

Purpose : It is now well established that infection and inflammation play an important role in the pathogenesis of ischemic brain damage. The loss of neutrophils from systemic circulation is an associated finding in injury mediated by granulocyte. Periventricular leukomalacia(PVL) caused by ischemia is the principal form of brain injury in premature infants. This study was conducted to evaluate whether the low neutrophil count is associated with periventricular leukomalacia(PVL) in premature infants. Methods : Retrospective review of medical records was undertaken. Subjects were premature infants with a birth weight of less than 1,500 gm, admitted to the Neonatal Intensive Care Unit of Kyungpook University Hospital. A complete blood count of peripheral blood was done within the 1st hour of life. Neutropenia was defined as absolute neutrophil count < $1,500/mm^3$, PVL as increased periventricular echodensities followed by cyst formation on ultrasonography or corresponding signs on brain MRI. Results : Thirteen infants out of a total population of 37 revealed neutropenia. Respiratory distress syndrome and requirement for respiratory support were not different between infants with neutropenia( neutropenia group) and infants without neutropenia(control group). Intraventricular hemorrhage (IVH) and grade 3 and 4 IVH were more frequent in neutropenia group(P<0.05). There was no statistically significant increase of PVL in neutropenia group. The neutrophil count was $18,760.0{\pm}10,266.1/mm^3$, $7,272.0{\pm}7,435.0/mm^3$ infants with PVL and $11,131.7{\pm}3,386.5/mm^3$, $2,407.5{\pm}1,933.1/mm^3$ in infants without PVL, respectively. The frequency of mechanical ventilation and artificial surfactant therapy was higher in infants with PVL compared with infants without PVL, but statistical analysis was not performed due to small number of subjects. Conclusion : A low number of neutrophils in the systemic circulation was not associated with an increased risk of PVL in premature infants.

• Journal of Korea Water Resources Association
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• v.51 no.12
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• pp.1195-1205
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• 2018

In the study, the water shortage of Boryeong Dam watershed ($163.6km^2$) was evaluated under future climate change scenario. The Soil and Water Assessment Tool (SWAT) was used considering future dam release derived from multiple linear regression (MLR) analysis. The SWAT was calibrated and verified by using daily observed dam inflow and storage for 12 years (2005 to 2016) with average Nash-Sutcliffe efficiency of 0.59 and 0.91 respectively. The monthly dam release by 12 years MLR showed coefficient of determination ($R^2$) of above 0.57. Among the 27 RCP 4.5 scenarios and 26 RCP 8.5 scenarios of GCM (General Circulation Model), the RCP 8.5 BCC-CSM1-1-M scenario was selected as future extreme drought scenario by analyzing SPI severity, duration, and the longest dry period. The scenario showed -23.6% change of yearly dam storage, and big changes of -34.0% and -24.1% for spring and winter dam storage during 2037~2047 period comparing with 2007~2016 period. Based on Runs theory of analyzing severity and magnitude, the future frequency of 5 to 10 years increased from 3 in 2007~2016 to 5 in 2037~2046 period. When considering the future shortened water shortage return period and the big decreases of winter and spring dam storage, a new dam operation rule from autumn is necessary for future possible water shortage condition.

• Journal of Korean Academy of Nursing
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• v.30 no.6
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• pp.1455-1466
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• 2000

The purpose of this study was to develop the framework of community-based home care nursing delivery system, and to demonstrate and evaluate the efficiency of it. The study was carned out over a period of 3years from September 1996 to August 1999. The researchers developed Standards for operations, this was all aimed toward a home care recording system, and an assessment intervention algorithm for various diseases quality control and standardization. In the center, 185 patients enrolled, and of the enrollments cerebrovascular disorder and cancer were the most prevailment diseases. Also, a home care nursing activity classification was developed in six domains. Those domains were assessment, medication, treatment, education and consultation, emotional care, and referral or follow-up care. Ten sub-domains were divided according to the systematic needs. Among these nursing activities, treatment, assessment, and education and consultation were frequently performed. In sub-domain classification, skin integrity, respiration, circulation, and immobility related care were provided most frequently. The cost of home care nursing per visit was also suggested. The cost include direct and indirect nursing care, management, and transportation cost. Also, the researchers tried to overcome the limitations of hospital-based home care to provide more accessible, efficient, safe, and stable home care nursing. Therefore, clients were referred from other patients, families, public health care centers, industries, and even hospitals. As a result of this study, several limitations of operation were found. First, it was difficult to manage and communicate with doctor in the emergency situations. Second, there was too much time spent for transportation. This was because they are only five nurses, who cover all of the areas of Seoul and nearby cities. Third, preparation for special care of home care nurses was lacking. Fourth, criteria for the termination of care and the frequency of home visits were ambiguous. Finally, interconnection with home care machinery company was so yely needed. New paragraphs' strategies for solving these problems were suggested. This study will be the basis of community-based home care nursing, and the computerized information delivery system for home care nursing in Korea.

• Journal of the Korean Institute of Landscape Architecture
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• v.15 no.2
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• pp.23-41
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• 1987

This study was conducted to investigate the planting status of the woody landscape plant species and to obtain some fundamental informations for improvement of production and sales circulation of the woody landscape plants. The details of 328 landscape projects which were carried out for 2 years from 1983 to 1984 were surveyed to investigate the utilization status of the woody landscpe plants. The results obtained are summarized as fellows ; 1) The utilization rate of the trees to the shrubs as woody landscape plants was 1 : 6 and that of the evergreens to deciduous plants was 1 : 4. The plant species which were most frequently used in landscaping were Buxus microphylla koreana, Juniperus chinensis, Zelkova serrata and Acer saccharinum, howevr, plants which were used in largest quantitites were Ligustrum obtusifolium, Forsythia koreana, Buxus microphylla koreans and Rhododendron yedoense var. poukhanense. 2) The number of plants planted among 3 shrub species(Ligustrum obtusifolium, Forsythia koreana and Buxus microphylla korana) exceeded half of the total number of shrubs planted for landscping, however, the number of plants planted among 8 tree species including Pinus koreainensis were about half of the total tree species. 3) The number of government price specified plant species was only 20%, but the utilization frequency of the price specified plants was as much as 6 times than unspecified plants and 85% of plants used in landscaping works were the price specified plants. The utilization rate of the price specified plants was significantly high in the shrubs than the trees and in the evergreen than deciduous plants. 4) The amounts in use of the price specified standardized plants were significantly more than those of unstandardized plants. When the plant heights are same, the plants having wider canopy or stem diameter were rather frequently used in the landscaping works. The ratio of the width of the canopy or stem diameter to the stem length of the plants in the Korean standard is significantly greater than that in the Japanese standard.

• Journal of Korea Water Resources Association
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• v.33 no.2
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• pp.229-235
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• 2000

Characteristics of hail occurred during 1989-1998 is studied. Hail is observed mainly at west coast, southwest inland, and Taegwallyong. Average diameter of hailstone is 0.6 cm, and 70% of the occurrence frequency of hail is observed at west coast. During winter and spring, the wet -bulb zero height (WBZ) is low enough to prevent the melting process of hail. But the lack of available low-level moisture (mean mixing ratio in lowest 100 hPa) makes the size of hail small. As a result, smaller size hail is observed frequently over west coast. On the contrary, WBZ is higher during summer, it means that hail is melted before it reaches ground, but the size of hail is bigger. Thus the larger hail is observed mainly Taegwallyong during summer. Hail is observed from 1100 LST to 1500 LST over west coast and around 1800 LST over Taegwallyong. It suggest that thermally driven mesoscale circulations such as land-sea breeze and mountain ridge-valley circulation aid in the formation of hail. Upper and surface air temperature is related to formation of hailstorm. Before formation of hailstorm in November 1998, the upper air temperature decreases. And hails is observed in the spot of strong temperature and dew point temperature gradient coincidently.