• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.228.2-228.2
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• 2014

Characteristics of high Fermi velocity, high mechanical strength, and transparency offer tremendous advantages for using graphene as a promising transparent conducting material [1] in electronic devices. Although graphene is a prospective candidate for touch sensor with strong mechanical properties [2] and flexibility, only few investigations have been carried out in the field of sensor as a device form. In this study, we suggest ultra-highly sensitive and transparent graphene touch sensor fabricated by single layer graphenes. One of the graphene layers is formed in the top panel as a disconnected graphene beam transferred on PDMS, and the other of the graphene layer is formed with line-patterning on the bottom panel of triple structure PET/PI/SiO2. The touch sensor shows characteristics of flexible. Its transmittance is approximately 75% where transmittance of the top panel and the bottom panel are 86.3% and 87%, respectively, at 550 nm wavelength. Sheet resistance of each graphene layer is estimated as low as $971{\Omega}/sq$. The results show that the conductance change rate (${\Delta}C/C0$) is $8{\times}105$ which depicts ultra-high sensitivity. Moreover, reliability characteristic confirms consistent behavior up to a 100-cycle test.

• Biomolecules & Therapeutics
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• v.20 no.6
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• pp.556-561
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• 2012

Steroid sulfatase (STS) is responsible for the conversion of estrone sulfate to estrone that can stimulate growth in endocrine-dependent tumors such as prostate cancer. Although STS is considered as a therapeutic target for the estrogen-dependent diseases, cellular function of STS are still not clear. Previously, we found that tumor necrosis factor (TNF)-${\alpha}$ significantly enhances steroid sulfatase expression in PC-3 human prostate cancer cells through PI3K/Akt-dependent pathways. Here, we studied whether bacterial lipopolysaccharides (LPS) which are known to induce TNF-${\alpha}$ may increase STS expression. Treatment with LPS in PC-3 cells induced STS mRNA and protein in concentration- and time-dependent manners. Using luciferase reporter assay, we found that LPS enhanced STS promoter activity. Moreover, STS expression induced by LPS increased PC-3 tumor cell migration determined by wound healing assay. We investigated that LPS induced IL-6 expression and IL-6 increased STS expression. Taken together, these data strongly suggest that LPS induces STS expression through IL-6 pathway in human prostate cancer cells.

• Molecules and Cells
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• v.23 no.2
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• pp.198-206
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• 2007

Hydroquinone is a toxic compound and a major benzene metabolite. We report that it strongly inhibits the activation of macrophages and associated cells. Thus, it suppressed the production of proinflammatory cytokines [tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-$1{\beta}$, IL-3, IL-6, IL-10, IL-12p40, IL-23], secretion of toxic molecules [nitric oxide (NO) and reactive oxygen species (ROS)] and the activation and expression of CD29 as judged by cell-cell adhesion and surface staining experiments. The inhibition was due to the induction of heme oxygenase (HO)-1 in LPS-activated macrophages, since blocking HO-1 activity with ZnPP, an HO-1 specific inhibitor, abolished hydroquinone's NO inhibitory activity. In addition, hydroquinone and inhibitors (wortmannin and LY294002) of the phosphatidylinositol-3 kinase (PI3K)/Akt pathway had very similar inhibitory effects on LPS-induced and CD29-mediated macrophage responses, including the phoshorylation of Akt. Therefore, our data suggest that hydroquinone inhibits macrophage-mediated immune responses by modulating intracellular signaling and protective mechanisms.

• Proceedings of the KIEE Conference
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• 1997.07b
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• pp.606-608
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• 1997

In this paper, Neuro-Fuzzy Controller(NFC), a fuzzy system realized using a neural network, is to adopt for the multivariable system. In the multivariable system, the interactive effects between the variables should be taken into account. A simple compensator, using the steady-state information can be obtained for open-loop stable systems, is presented to cope with this problem. However, it should be supposed that the plant is unknown to the control system designer, but an estimate of the DC gain has been obtained by carrying out experiments on the plant. Also, if the variables are not combinated completely, it is difficult to design the controller. Therefore, we design a neuro-fuzzy controller which controls a multivariable system with only input output informations, and compare its performance with that of a PI controller. In the proposed controller, the construction of the membership functions and rule base, which is highly heuristic, can be achieved using a training process. This allows the combination of knowledge of human experts and evidence from input-output data.

• Plant Resources
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• v.6 no.3
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• pp.205-210
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• 2003

Ginseng(Panax ginseng C.A. Meyer) is a perennial herbaceous plant which grows very slowly. It takes about 3 to 4 years from seeding to collecting the ripe seeds and the ginseng propagation is very difficult. and so, it is very difficult to breed ginseng plant. Ginseng tissue culture was started from at 1960, and ginseng commercial product by in vitro callus culture was saled, however upto now, regenerants were not planted to soil normally. Recently, plant genetic engineering to produce transgenic plants by introducing useful genes has been advanced greatly. In a present paper, transformation of ginseng plants was achieved by co-cultivation with Agrobacterium harboring the binary vector coding Proteinase-II gene, which confer resistant or tolerant to insect pests, The binary vector for transformation was constructed with disarmed Ti-plasmid and with double 35S promoter. The NPT II gene and introduced genes of the transgenic ginseng plants were successfully identified by the PCR. Especially the transgenic ginseng plants were regenerated using new techniques such as repetitive single somatic embryogenesis.

• Journal of Haehwa Medicine
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• v.16 no.2
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• pp.349-353
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• 2007

Hyperhidrosis is a condition characterized by excessive sweating. It can be generalized or focal. Generalized hyperhidrosis involves the entire body and is usually part of an underlying condition, most often an infectious, endocrine or neurologic disorder. Focal hyperhidrosis is idiopathic, occurring in otherwise healthy people. The condition carries a substantial psychological and social burden, since it interferes with daily activities. We treated two male patients who had hyperhidrosis on the head. In the point of Differentiation of Syndrom(辨證), these subjects were diagnosed as Bi-Wi-Gi-Her (Pi-Wei-Qi-Xu 脾胃氣虛) and was administered revised Bojungikgi-tang (reserved Buzhongyiqi-tang, 補中益氣湯加味方). All of two cases had anorexia, dyspepsia, fatigue. After treatment hyperhidosis and other symptoms improved.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.45 no.5
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• pp.343-346
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• 2000

Rye breeding using F$_1$ hybrid began about 30 years ago, when cytoplasmically inherited forms of male sterility (CMS) and corresponding nuclear restorers were detected. It is very important to produce inbred lines for making hybrid lines because of strong self-incompatibility in rye. Among the 456 rye germplasms used in hybrid breeding scheme, 24 lines (5.3%) had the above 60% of self-fertility, and six lines of them were selected for their good agronomic characteristics and were used for subsequent inbreeding program. The average self-fertility of selected six lines was 78.4%, ranging from 72.2 to 99.5%. Genetic analysis for the self-fertility using $F_2$ populations showed that the segregation of self-fertile and sterile plants in F$_2$populations could be fit into 3 to 1 ratio suggesting self-fertility in rye be controlled by one major gene. The four different self-fertile lines, PI237923, 5C11, 5G5 and Florida black, had the same self-fertility gene because their F$_2$ plants showed almost the same self-fertility as their parents and showed no genetic segregation.

• Proceedings of the KIPE Conference
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• 2001.07a
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• pp.430-433
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• 2001

When the vector control, which does not need a speed signal from a mechanical speed sensor, it is possible to reduce the cost of the control equipment and to improve the control performance in many industrial application. This paper describes a rotor speed identification method of induction motor based on the theory of flux model reference adaptive system. The estimator execute the rotor speed identification so that the vector control of the induction motor may be achieved. The improved auxiliary variable of the two model are introduced In perform accurate rotor speed estimation. The control system is composed of the PI controller for speed control and current controller using space voltage vector PWM technique. High speed calculation and processing for vector control is carried out by TMS320C31 digital signal processor. Validity of the proposed control method is verified through simulation and experimental result.

• Proceedings of the Korean Society of Computer Information Conference
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• 2021.01a
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• pp.183-184
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• 2021

기존의 스타일러는 옷 건조, 살균 기능을 가지고 있으나, 비용이 비싸며 공간을 차지하는 단점을 가지고 있다. 알림 기능을 가지는 스마트 옷장은 옷장위에 설치된 라즈베리파이 디스플레이에 간단한 날씨정보를 출력하여 그 날의 날씨정보를 시간소비 없이 간편하게 습득할 수 있으며, 한줄 뉴스를 통하여 그 날의 소식을 간편하게 알 수 있다. 또한 옷장 내부에 설치된 아두이노가 온습도 센서와 미세먼지 센서를 통제하여 옷장 내부의 온도, 습도, 미세먼지 농도를 디스플레이를 통해 알 수 있으며, 습도가 높거나, 미세먼지 농도가 높을 경우에 옷장 내부에 부착된 쿨링팬이 자동으로 작동하여 옷장 내부를 환기시킴으로써 습도를 낮추고 먼지, 냄새 등을 제거해주는 효과가 있다. 그리고 습도나 미세먼지 수치가 낮아지면 자동으로 쿨링팬의 작동은 멈춰진다. 또한 미세먼지, 온습도 값에 따라 3색 LED가 색이 변화한다. 이런 스마트옷장으로 바쁜 현대 사회에서 사용자들의 시간을 절약해주고 옷의 관리해줌으로써 편리함을 제공한다.

• Nuclear Medicine and Molecular Imaging
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• v.42 no.1
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• pp.8-16
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• 2008

Purpose: To assess the effect of extracranial-intracranial (EC-IC) bypass surgery on hemodynamic improvement, we evaluated serial regional cerebral hemodynamic change of the middle cerebral artery (MCA) in symptomatic patients with atherosclerotic occlusion of the internal carotid artery (ICA) or MCA using $^{99m}Tc$-ECD acetazolamide stress brain perfusion SPECT (Acetazolamide SPECT). Materials and Methods: The patients who had suffered a recent stroke with atherosclerotic ICA or MCA occlusion underwent EC-IC bypass surgery and Acetazolamide SPECT at 1 week before and three to six months after surgery. For image analysis, attenuation corrected images were spatially normalized to SPECT templates with SPM2. Anatomical automated labeling was applied to calculate mean counts of each Volume-Of-Interest (VOI). Seven VOIs of bilateral frontal, parietal, temporal regions of the MCA territory and the ipsilateral cerebellum were defined. Using mean counts of 7 VOIs, cerebral perfusion index and perfusion reserve index were calculated. Results: Seventeen patients (M:F =12:5, mean age $53{\pm}2yr$) were finally included in the analysis. The cerebral blood flow of the parietal region increased at 1 week (p = 0.003) and decreased to the preoperative level at 3-6 months (p = 0.003). The cerebrovascular reserve of the frontal and parietal regions increased significantly at 1 week after surgery (p<0.01) and improved further at 3-6 months. Conclusion: Cerebrovascular reserve of the MCA territory was significantly improved at early postoperative period after EC-IC bypass and kept improved state during long-term follow-up, although cerebral blood flow did not significantly improved. Therefore, cerebrovascular reserve may be a good indicator of postoperative hemodynamic improvement resulted from bypass effect.