• 제목/요약/키워드: Chronic Inflammatory Demyelinating Polyneuropathy

검색결과 18건 처리시간 0.022초

Insight into the prognostic factors of chronic inflammatory demyelinating polyneuropathy

  • Baek, Seol-Hee
    • Annals of Clinical Neurophysiology
    • /
    • 제22권1호
    • /
    • pp.8-12
    • /
    • 2020
  • Chronic inflammatory demyelinating polyneuropathy (CIDP) is an immune-mediated neuropathy with heterogeneous features. Appropriate treatment will produce a favorable outcome, but a poor treatment response and severe disability have also been reported. The roles of the clinical phenotypes and electrophysiological features of CIDP as well as of autoantibodies against nodal and paranodal proteins have been highlighted previously due to their association with the treatment response and long-term prognosis. This review addresses the diverse factors associated with the prognosis of CIDP.

시신경염이 동반된 아급성염증탈수초다발신경병 (Subacute Inflammatory Demyelinating Polyneuropathy Combined with Optic Neuritis)

  • 김시은;박강민;박진세;하삼열;김성은;김종국;신경진
    • Annals of Clinical Neurophysiology
    • /
    • 제15권1호
    • /
    • pp.13-18
    • /
    • 2013
  • It was sometimes difficult to differentiate between acute-onset chronic inflammatory demyelinating polyneuropathy (A-CIDP) and subacute inflammatory demyelinating polyneuropathy (SIDP). The CNS involvement of these polyneuropathies has rarely reported in the literature. We present the case of a 42-year-old man who developed rapidly developing inflammatory demyelinating polyneuropathy followed by right optic neuritis. This case showed progressive motor weakness and sensory dysfunction with time to nadir at 8 weeks, demyelination in nerve conduction study, no other etiology of neuropathy, no relapse during follow-up of 18 months, good response to steroid and complete recovery which favor SIDP more than A-CIDP. We experienced the case of SIDP associated with optic neuritis.

Colorectal carcinoma and chronic inflammatory demyelinating polyneuropathy: is there a possible paraneoplastic association?

  • Adnan Malik;Faisal Inayat;Muhammad Hassan Naeem Goraya;Gul Nawaz;Ahmad Mehran;Atif Aziz;Saad Saleem
    • Clinical Endoscopy
    • /
    • 제56권2호
    • /
    • pp.245-251
    • /
    • 2023
  • A plethora of paraneoplastic syndromes have been reported as remote effects of colorectal carcinoma (CRC). However, there is a dearth of data pertaining to the association of this cancer with demyelinating neuropathies. Herein, we describe the case of a young woman diagnosed with chronic inflammatory demyelinating polyneuropathy (CIDP). Treatment with intravenous immunoglobulins and prednisone did not improve her condition, and her neurological symptoms worsened. Subsequently, she was readmitted with exertional dyspnea, lightheadedness, malaise, and black stools. Colonoscopy revealed a necrotic mass in the ascending colon, which directly invaded the second part of the duodenum. Pathologic results confirmed the diagnosis of locally advanced CRC. Upon surgical resection of the cancer, her CIDP showed dramatic resolution without any additional therapy. Patients with CRC may develop CIDP as a type of paraneoplastic syndrome. Clinicians should remain cognizant of this potential association, as it is of paramount importance for the necessary holistic clinical management.

사람면역결핍바이러스 감염과 연관된 만성염증탈수초다발신경병증 (Chronic Inflammatory Demyelinating Polyneuropathy Associated with HIV-Infection)

  • 허소영;안보영;오세진;박영은;김대성
    • Annals of Clinical Neurophysiology
    • /
    • 제13권2호
    • /
    • pp.97-100
    • /
    • 2011
  • Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired immune-mediated polyneuropathy. Corticosteroids, intravenous immunoglobulin (IVIG) and plasmapheresis have been reported to be effective treatment. Rarely, CIDP can occur in the patients with HIV infection. The clinical features and electrophysiological findings of CIDP are known to be similar in patients with and without HIV infection. We report a 30-year-old male with HIV infection associated CIDP who improved after the administration of intravenous immunoglobulin and long term oral prednisone.

하지 위약감 및 저림을 호소하는 만성 염증성 탈수초성 다발신경병증 환자에 대한 독활기생탕과 약침을 포함한 한의복합치료 증례보고 1례 (A Case Report of Korean Medicine Therapy including Duhuo Jisheng Tang and Pharmacoacupuncture for a Chronic Inflammatory Demyelinating Polyneuropathy Patient Complaining Weakness and Numbness in Lower Extremity)

  • 황예채
    • 대한예방한의학회지
    • /
    • 제28권1호
    • /
    • pp.159-168
    • /
    • 2024
  • This case study aims to report Korean medicine treatment's response to weakness and numbness in chronic inflammatory demyelinating polyneuropathy (CIDP) patient. The patient received Korean medicine treatment during hospitalization, including Duhuo Jisheng Tang and pharmacoacupuncture. The assessment was performed using the Functional Independence Measure (FIM), Numeric Rating Scale (NRS) for numbness, and Oswestry Disability Index (ODI). After 21 days of treatment, the FIM improved from 82 to 126, NRS improved from 6 to 2, and ODI improved from 37 to 8. There were no side effects after receiving Korean medicine. This case suggests that Korean medicine treatment can induce treatment response for lower extremity weakness and numbness in CIDP patients.

Optic neuritis and multiple cranial neuropathies in patient with chronic inflammatory demyelinating polyneuropathy

  • Bae, Min-Jeong;Lee, Joonwon;Eun, Jeong Ik;Shin, Kyong Jin
    • Annals of Clinical Neurophysiology
    • /
    • 제24권2호
    • /
    • pp.59-62
    • /
    • 2022
  • Chronic inflammatory demyelinating polyneuropathy (CIDP) is a chronic recurrent acquired immune-mediated disease of the peripheral nerves that presents with progressive sensory and motor deficits in all four limbs. Cranial nerve involvement is not as common as in Guillain-Barre syndrome, and central nervous system involvement including optic neuritis has rarely been reported in patients with CIDP. We recently experienced a case with classic CIDP involving bilateral facial and trigeminal nerves, right lower cranial nerves, and the right optic nerve.

급성 염증성 탈수초성 다발성 신경병의 임상 양상을 보인 IgA λ형 Monoclonal Gammopathy of Undetermined Significance 1례 (A Case of IgA λ Monoclonal Gammopathy of Undetermined Significance Mimicking Acute Inflammatory Demyelinating Polyradiculoneuropathy)

  • 이영배;전성호;한동철;신동진
    • Annals of Clinical Neurophysiology
    • /
    • 제7권1호
    • /
    • pp.17-19
    • /
    • 2005
  • Polyneuropathy that is associated with monoclonal gammopathy of undetermined significance (MGUS) similar to chronic inflammatory demyelinating polyneuropathy (CIDP) has been reported before, whereas a connection to acute inflammatory demyelinating polyneuropathy (AIDP) has not been. A 52 year-old man was presented with ascending paralysis beginning 1 day ago. Neurological examinations showed facial diplegia and decreased motor power and deep tendon reflexes in all extremities. On electrophysiologic study, sensorimotor polyneuropathy was observed. Protein-and immunoelectrophoresis revealed IgA $\lambda$ monoclonal gammopathy. High dose steroid therapy was given and the symptoms improved slightly.

  • PDF

Acute-onset chronic inflammatory demyelinating polyneuropathy following hepatitis A virus infection

  • Jung, Eui Sung;Kim, Ye Sel;Min, Ju-Hong;Kang, Kyusik;Lee, Jung Ju;Park, Jong-Moo;Kim, Byung-Kun;Kwon, Ohyun
    • Annals of Clinical Neurophysiology
    • /
    • 제19권1호
    • /
    • pp.50-53
    • /
    • 2017
  • An infection is less likely to elicit chronic inflammatory demyelinating polyneuropathy (CIDP) than Guillain-$Barr{\acute{e}}$ syndrome. We here report a case of acute-onset CIDP following hepatitis A virus infection and briefly comment on the potential mechanisms regarding the induction and chronicity of autoimmunity after a viral infection.

만성적 경과관찰을 보이는 Guillain-Barré Syndrome 환자 1례 (A Clinical Case Study of Guillain-Barré Syndrome with Chronic Progression)

  • 노지애;장재원;이기언;홍정수;김동진
    • 대한한방내과학회지
    • /
    • 제39권1호
    • /
    • pp.76-83
    • /
    • 2018
  • Objectives: This case study reports on one patient presenting atypical and chronic disorders after being diagnosed with $Guillain-Barr{\acute{e}}$ Syndrome (GBS). Methods: One patient was treated by Yeongseonjetong-eum-gami, Taklisodok-eum-gami, electroacupuncture, and physical therapy. Any improvement in symptoms was assessed by measuring changes in the motor grade of upper limb weakness, the numerical rating scale (NRS) of lower limb numbness, and GBS scores. Results: After 24 days of treatment, the patient's symptoms of GBS showed little improvement. Conclusions: Traditional Korean medical treatment appeared to be effective in reducing GBS symptoms, but more research is required to confirm these results. When treating GBS patients, the clinician should put effort into distinguishing GBS from other nervous disorders, such as acute onset Chronic Inflammatory Demyelinating Polyneuropathy (CIDP).