• Title/Summary/Keyword: Chonnam

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Effect of Polyethylenimine Type in Polylactic acid Nanoparticles/DNA Complex on the Transfection Efficiency

  • Chae, Jong-Hyuck;Park, Yu-Mi;Kim, Kyeong-Man;Lee, Yong-Bok;Shin, Sang-Chul;Oh, In-Joon
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.425.1-425.1
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    • 2002
  • Nanoparticles of polylactic acid (PLA) and polyethylenimine (PEI) as an effective gene delivery agent were prepared and characterized. As a model plamid DNA. PME185/$\beta$-gal. a mammalian expression vector. and fluorescence enhancing protein (pEGHP) were used. The effects of PEI type on the physical properties of nanoparticles and transfection efficiency were examined. (omitted)

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