• 제목/요약/키워드: Chiral phase-transfer catalysts

검색결과 3건 처리시간 0.018초

Highly efficient ortho-fluoro-dimeric cinchona-derived phase-transfer catalysts

  • Park, Hyeung-Geun;Jeong, Byeong-Seon;Lee, Jeong-Hee;Yoo, Mi-Sook;Jew, Sang-Sup
    • 대한약학회:학술대회논문집
    • /
    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
    • /
    • pp.250.3-251
    • /
    • 2003
  • A series of cinchona alkaloid-derived dimeric quaternary ammonium salts were prepared as chiral phase-transfer catalysts by the introduction of various functional groups on the phenyl ligand. Among them. the 2-F-substituted derivative 21 showed the highest enantioselectivity in the alkylation of the glycine anion equivalent 1 (97->99 % ee).

  • PDF