• The Journal of Korean Medicine
• /
• v.33 no.3
• /
• pp.200-230
• /
• 2012

Objectives: Ginseng, Panax ginseng C. A., white ginseng, has been used for thousands of years in Traditional Korean Medicine. Red ginseng can be made by a steaming process of white ginseng changing a variety of ginsenosides and ingredients such as dencichine. This article reviews red ginseng for mechanisms for pharmacodynamics and toxicity based on the content of ginseng's active ingredients, ginsenoside changed by steaming. Methods: The following electronic databases were searched: PubMed, Science Direct and Chinese Scientific Journals full text database (CQVIP), and KSI (Korean Studies Information) from their respective inceptions to June 2012. Results: Compared with unsteamed ginseng, the content of ginsenosides Rg2, Rg3, Rg5, Rh1, Rh2 and Rk1 called red ginseng-specific ginsenosides increased after the steaming process. Different ginsenosides have shown a wide variety of effects such as lowering or raising blood sugar and blood pressure or stimulating or sedating the nervous system. Especially, the levels of Rg2, Rg3, Rg5, Rh1, Rh2 and Rk1 were increased by the steaming process, showing a variety of pharmacodynamics in biological systems. Also, various processing methods such as puffing and fermentation have been developed in processing crude ginseng or red ginseng, affecting the content of ginseng's ingredients. The safety issue could be the most critical, specifically, on changed ginseng's ingredients such as dencichine. The level of dencichine was significantly reduced in red ginseng by the steaming process. In addition, the possible toxicity for red ginseng was affected by cytochrome P450, a herbal-drug interaction. Conclusions: The variety of pharmacological and toxicological properties should be changed by steaming process of Panax ginseng C. A., white ginseng. Even if it is not sure whether the steaming process of white ginseng would be better pharmacologically, it is sure that steaming reduces the level of dencichine causing a lower toxicity to the nervous system.

• Korean Journal of Acupuncture
• /
• v.20 no.4
• /
• pp.99-119
• /
• 2003

Objectives : The Jap Byoung(雜病) of the Young Chu(靈樞), one of the classical book of oriental medicine contains symptoms and remedies for various diseases that can be seen on human body. But it is too difficult to understand the Jap Byoung(雜病), because it is written in old chinese and there are many printer's error and omissions or adds in this book. As a consequence of above reason, the writer of this article has researched to find out the exact meaning of that. Methods : So in this part we study a woodblock-printed book of successive generation and view of annotators, and add adding notes, adjustment, translation to exact comprehension of the original text. Results & conclusions : The principle ideas of the thesis can be summarized as follows: The Jap Byoung(雜病) is consist of five part. In chapter 1, we present symptoms occurred by the upstream current of Qi(氣逆) and their treatments by taking meridian flowing the body parts on which the symptoms occur. In chapter 2, we deal with symptoms such as ikgun(?乾), a pain of the knee(膝中痛), huby(喉痺), epistaxis(?血), lumbago(腰痛), anger(怒), a pain of the jaw(痛), a pain of the nape(項痛) and their remedies. In chapter 3, since abdominal inflation occurs when the Qi(氣) of the five viscera(五臟) is damaged or go upstream, I discussed that the treatment should be given by taking the meridian accordingly. In chapter 4, we deal with the remedy for heartache, and different meridians to be taken by symptom, and parts on which needle to be used, and detailed remedies. In chapter 5, we present other diseases, detailed body parts to be cured and remedies by referring symptoms for a pain of the jaw(痛), the upstream current of Qi(氣逆), hiccup, etc. Especially, we introduce a part of Doinbup(導引法) for wegurl(?厥) and remedies for hiccup such as inducing sneeze by stimulating nostrils, holding one's breath, etc.

• The Journal of Korean Medical History
• /
• v.16 no.2
• /
• pp.105-140
• /
• 2003

1. "Eonhaegukupbang(諺解救急方)" is a medical book that was published and edited by Naeuiwon(內醫院) under the king's command in the Joseon Dynasty in 1607. 2. It includes the contents but doesn't a preface and an epilogue. And several medical treatments and herb medicines of diseases from emergency are noted in the original text of "Eonhaegukupbang(諺解救急方)". The book is composed of two volume and 181 pages. 3. A number of cultural properties and medical books were lost and all people of the nation were suffered from poverty and diseases during Japanese invasion of Korea in 1592. Then some books of Korean translation of Chinese classics were edited under the king's command with the intention of recompiling the lost books and easy application of medical knowledge for the people. 4. "Eonhaegukupbang(諺解救急方)" admit several books and notes the reference books at the beginning or the end. This book has 37 kinds of reference books, and those are "Boncho(本草)", "Uihakgangmok(醫學綱目)", "Uihakimmun(醫學入門)", "Deukhyobang(得效方)", "Uihakjeongjeon(醫學正傳)", "Dan-gyebang(丹溪方)" and so on in the main. 5. "Gugupbang(救急方)"(in the Sejo Dynasty) is similar to "Eonhaegukupbang(諺解救急方)" in aspect of helping the people with convenient contents. But it is a point of difference that the composition and contents of "Eonhaegukupbang(諺解救急方)" are more centering about the medical prescriptions than those of "Gukupbang(救急方)". 6. "Eonhaegukupbang(諺解救急方)" is very similar to the "Gukupmun救急門" in the "Donguibogam(東醫寶鑑)" in the contents and construction of the list. "Eonhaegukupbang(諺解救急方)" was published during the writing of "Donguibogam(東醫寶鑑)", so it has a deep meaning that "Eonhaegukupbang(諺解救急方)" is a condensed version of easy application for the civilian by regulating already established section. 7. It seems that "Eonhaegukupbang(諺解救急方)" has continuous influences in the part of emergency in the "Donguibogam(東醫寶鑑)"

• Culinary science and hospitality research
• /
• v.21 no.4
• /
• pp.251-270
• /
• 2015

This study was, based on traditional know-how indigenous to Korea, to systemize the knowledge on how to improve health by dining, and to make the best of it statistically. For this purpose, the knowledge in the Sikryo-chanryo(食療纂要), in Korean pronunciation and Siglyochan-yo in Chinese characters, which is an old text referring to diet therapy peculiar to Korea, was compiled into a database and analyzed statistically. Data processing was used as a 'Relational data model'. In addition, we have used nine data table to express diet therapy peculiar to Korea in the Siglyochan-yo. The software used for data construction was Microsoft Access 2014. As a result, the Sikryo-chanryo database, which can provide information on both disease treatment by food, medicines, and gourmet ingredients applicable to every kind of symptom, as well as the names of disease, was set up at in a PC interface. By employing the 'Relational data model', we can replace researching in the conventional method by employing the database.

• Journal of Pharmacopuncture
• /
• v.3 no.2
• /
• pp.1-25
• /
• 2000

We were trying to study the validity of Puffer fish's poison(Tetrodotoxin- TTX) to make a traditional Korean Medical treatment. The following conclusions were made after literary studies. 1. The first record of the puffer fish dates back 2000 years ago in the Chinese text Book of Mountain and Sea and other texts from the similar period. 2. Puffer fish's poison IS known as tetrodotoxin which is an amino perhydroquinazoline compound. It has a chemical formula of $C_{11}H_{17}N_3O_8$ in the hemiacetal structure and has the molecular weight of 319. 3. Tetrodotoxin (TTX) plays a role as potent neurotransmitter blocker by blocking the $Na^+$ -gate channel which hinders the influx of $Na^+$ ion into the cell. 4. Symptoms of the puffer fish poisoning ranges from blunted sense in the lips and tongue, occasional vomiting in the first degree to sudden descending of the blood pressure, apnea, and other critical conditions in the fourth degree. Intoxication of the puffer fish poison progresses at a rapid pace as death may occur after an hour and half up to eight hours in maximum. Typical death occurs after four to six hours. 5. Ways to treat the puffer fish poisoning include gastric irrigation, induce vomiting, purgation, intravenous fluid injection, and correcting electrolytic imbalance and acidosis. In cases of dyspnea, apply oxygen inhalation and conduct artificial respiration. 6. Tetrodotoxin (TTX) may be applied in treating brain disorders, ocular pain, excess pain in the large intestine and ileum, and relieving tension of the skeletal museles, neuralgia, rheumatism, arthritis, and etc. 7. In terms of Oriental medicine, the puffer fish poison has characteristics of sweet, warm, and poisonous. It's known efficacies are to tonify weakness, dispel damp, benefit the lower back, relieve hemorrhoid, kills parasites, remove edema, and so forth. And the puffer fish eggs processed with ginger are said to be effective against tuberculosis and lung cancer, thus, it's validity must be investigated and further research should be followed.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.19 no.2
• /
• pp.295-303
• /
• 2005

YangDongChangHwaHuRok(兩東唱和後錄)is a book that organized the conversation between Joseon physician Ki-DuMun(奇斗文) and Japanese Acupuncture specialist Murakami Tanio(村上溪南) and others when they visited the quarters where the Choson Delegation(朝鮮通信使) were staying in, while the Choson Delegation party were visiting Japan in 1711. YangDongChangHwaHuRok(兩東唱和後錄) was discovered in the process of gathering medicine-related historical documents of the Choson Dynasty that is spread out all over the Japanese region, with the help from Japanese and Chinese scholars. This was part of the Co-Examination-Research-Process of korean medical documents that are located in the East Asia traditional medical region, which was promoted by the Korean Institute of Oriental Medicine in 2003. This paper has analyzed in-depth, with an inner-medical view, the academic exchange content of YangDongChangHwaHuRok(兩東唱和後錄) by following the order of the main text. With this examination, we were able discover new facts about the interest in Primary Symptom(是動病) and Secondary Symptom(所生病) of 17th century doctors, a new hypothesis on the diffusion of HeoYim(許任)'s ChimGuKyungHeomBang(鍼灸經驗方) in Japan, the existence of a new acupuncture tool called ChongChim(腫鍼), and the influence of the 18th comtemporay famous traditional medical books (it is called UiHakYipMun(醫學入門) and ShinEungKyung(神應經) on the 18th century East Asian medical circle. We were also able to ascertain the specific medical content that was diffused to the Japanese medical circle by the Korean medical circle.

• The Journal of Korean Obstetrics and Gynecology
• /
• v.20 no.3
• /
• pp.1-12
• /
• 2007

Purpose: Uterine leiomyomas (fibroids) are common estrogen-dependent uterine tumors. Houttuynia cordata thunberg has cancer-preventing properties and often used in Chinese medicine. In the present study we used Houttuynia cordata thunberg to determine its effect on cell proliferation and apoptosis in human uterine leiomyoma cells. Methods: Primary cultured human uterine leiomyoma cells were treated with Houttuynia cordata thunberg. Cell viability analysis was analyzed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTS) assay and Flow cytometry was performed to ascertain the effects Houttuynia cordata thunberg. Expression of cell cycle related proteins and apoptosis related proteins were evaluated by Western blot analysis. Results: Cell viability was significantly influenced by Houttuynia cordata thunberg treatment in a dose-dependent manner in leiomyoma cells compare to normal myometrial cells. Flow cytometric analysis showed that Houttuynia cordata thunberg induced Sub G1 arrest. DNA fragmentation assay was carried out and apoptosis was detected. Activation of caspase-3, down-regulation of Bcl-2, with concomitant increase in p21 was observed. Houttuynia cordata thunberg treatment of uterine leiomyoma cellsresulted in a concentration-dependent cell death induced via the caspase dependent mechanism. Conclusion: These results suggest that Houttuynia cordata thunberg treatment in uterine leiomyoma cells leads to growth inhibition and induced apoptosis. These results suggest that Houttuynia cordata thunberg will be a promising agent for use in therapeutics agents against human uterine endometrial cancer.

• Journal of the Korea Convergence Society
• /
• v.10 no.8
• /
• pp.21-26
• /
• 2019

This paper proposes a fatigue recognition method using the C4.5 algorithm. Based on domestic and international studies on fatigue evaluation, we have completed the fatigue self - assessment scale in combination with lifestyle and cultural characteristics of Chinese people. The scales used in the text were applied to 58 sub items and were used to assess the type and extent of fatigue. These items fall into four categories that measure physical fatigue, mental fatigue, personal habits, and fatigue outcomes. The purpose of this study is to analyze the leading causes of fatigue formation and to recognize the degree of fatigue, thereby increasing the personal interest in fatigue and reducing the risk of cerebrovascular disease due to excessive fatigue. The recognition rate of the fatigue recognition system using the C4.5 algorithm was 85% on average, confirming the usefulness of this proposal.

• The Journal of Korean Medical History
• /
• v.31 no.2
• /
• pp.53-62
• /
• 2018

It is known that the development of medical science is influenced by various social environmental factors. Historically, Chinese Medicine developed the most during the Song Yuan dynasty, and the reason for this was known to be due to socio-political factors. According to recent studies, however, this period also had severe changes in climate and environment. Therefore, this study was conducted under the premise that this change in climate and environment influenced medical development. When looking at the coldness of the 11th~12th century and data indicating warming before and after this period, the Song Yuan dynasty went through drastic periods of climate change. Therefore, diseases related to heat such as bubonic plague, measles, and malaria were common. Furthermore, due to occasional wars during the Song Yuan dynasty, social unrest was aggravated and infectious diseases spread due to land development and environmental pollution. As the health of people were threatened due to these factors, the printing and distribution of medical text were encouraged, and during this process, the great 4 doctors of Jin-Yuan appeared. The reason why they studied cures for infectious diseases due to heat was related to climatic environment change. The development in medical science is closely related to socio-political factors, however the change in climatic environments are inevitably related to disease emergence as well. Therefore, it should always be taken into consideration as an important factor that promotes development in medical science.

• The Journal of the Convergence on Culture Technology
• /
• v.8 no.1
• /
• pp.395-402
• /
• 2022

The film House of Hummingbird intersects Korean modern history and personal history through the eyes of a teenage girl, and closely explores how patriarchy and Korean capitalism leave traces and internal impressions on the growing up of the female subject. This film is a meaningful text in terms of showing what changes can occur when the subject is transformed from a boy to a girl in the narrative of growth and when a feminist point of view is entered. House of Hummingbird reveals the weakness of the patriarchal symbolic order through the gaze of a teenage girl in the episodic narrative composition, and also discovers the possibility of close relationships and bonds between women in the gaps. In particular, Yeong-ji, the main character girl Eun-hee's Chinese language school lecturer, is a new female character that has never been seen in Korean teenage films. As a result, in House of Hummingbird, we meet a new female subject who negotiates the pain of growth in a 'good enough' condition.