Many hydropower stations in southwest China are located in regions of brittle rock mass with high geo-stresses. Under these conditions deep fractured zones often occur in the sidewalls of the underground caverns of a power station. The theory and methods of fracture and damage mechanics are therefore adopted to study the phenomena. First a flexibility matrix is developed to describe initial geometric imperfections of a jointed rock mass. This model takes into account the area and orientation of the fractured surfaces of multiple joint sets, as well as spacing and density of joints. Using the assumption of the equivalent strain principle, a damage constitutive model is established based on the brittle fracture criterion. In addition the theory of fracture mechanics is applied to analyze the occurrence of secondary cracks during a cavern excavation. The failure criterion, for rock bridge coalescence and the damage evolution equation, has been derived and a new sub-program integrated into the FLAC-3D software. The model has then been applied to the stability analysis of an underground cavern group of a hydropower station in Sichuan province, China. The results of this method are compared with those obtained by using a conventional elasto-plastic model and splitting depth calculated by the splitting failure criterion proposed in a previous study. The results are also compared with the depth of the relaxation and fracture zone in the surrounding rock measured by field monitoring. The distribution of the splitting zone obtained both by the proposed model and by the field monitoring measurements are consistent to the validity of the theory developed herein.
The genetic structure and diversity of 15 Chinese indigenous chicken breeds was investigated using 29 microsatellite markers. The total number of birds examined was 542, on average 36 birds per breed. A total of 277 alleles (mean number 9.55 alleles per locus, ranging from 2 to 25) was observed. All populations showed high levels of heterozygosity with the lowest estimate of 0.440 for the Gushi chickens, and the highest one of 0.644 observed for Wannan Three-yellow chickens. The global heterozygote deficit across all populations (FIT) amounted to 0.180 (p<0.001). About 16% of the total genetic variability originated from differences between breeds, with all loci contributing significantly to this differentiation. An unrooted consensus tree was constructed using the Neighbour-Joining method and pair-wise distances based on marker estimated kinships. Two main groups were found. The heavy-body type populations grouped together in one cluster while the light-body type populations formed the second cluster. The STRUCTURE software was used to assess genetic clustering of these chicken breeds. Similar to the phylogenetic analysis, the heavy-body type and light-body type populations separated first. Clustering analysis provided an accurate representation of the current genetic relations among the breeds. Remarkably similar breed rankings were obtained with all methods.
Purpose: To systematically review efficacyand safety of robotic gastrectomy (RG) compared with conventional laparoscopic gastrectomy (LG) for gastric carcinoma. Materials and Methods: A systematic literature search was carried out using PubMed, Cochrane Library, CBM, CNKI, WanFang, VIP and other sources like relevant references to obtain comparative studies assessing the effectiveness and safety between RG and LG published between 2013 and 2016. Then the literature was screened and the data were extracted by 2 independent reviewers. The quality of the literature was assessed, and the data analyzed using Stata/SE 14 software. Fixed effects or random effects models wereapplied according to heterogeneity. Results: A total of 12 non-randomized observational clinical studies involving 3,580 patients were included, of which 1,096 had undergone RG and 2,484 had received LG. The results of the meta-analysis showed in terms of effectiveness, RG was associated with less blood loss, less time to first flatus and greater number of harvested lymph nodes, but there were no significant differences in proximal and distal resection margins, compared with LG. In terms of efficiency, RG was associated with shorter hospital stay, but longer operative time. In terms of safety, there were no statistically significant differences in complications, mortality and conversions between RG and LG. Conclusions: RG can achieve comparable or better short-term and radical effects than LG, with respect to effectiveness, efficiency and safety in treatment of gastric carcinoma. Future studies involving RG should focus on decreasing operative time and reducing cost. Moreover, there is a need for randomized controlled trials comparing the two techniques with long-term follow-up.
Background: DICER, one of the microRNA (miRNA) biogenesis proteins, is involved in the maturation of miRNAs and is implicated in cancer development and progression. The results from previous epidemiological studies on associations between DICER rs1057035 polymorphism and cancer risk were inconsistent. Thereforewe performed this meta-analysis to summarize possible associations. Materials and Methods: We searched all relevant articles on associations between DICER rs1057035 polymorphism and cancer risk from PubMed, EMBASE, Chinese Biomedical Literature and Chinese National Knowledge Infrastructure until August 2014. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated to assess any associations. Heterogeneity tests, sensitivity analyses and publication bias assessments were also performed in this meta-analysis. All analyses were conducted using STATA software. Results: Seven case-control studies, including 4,875 cancer cases and 7,800 controls were included in the meta-analysis. Overall, the results indicated that the C allele of DICER rs1057035 polymorphism was significantly associated with decreased cancer risk in allelic comparison, heterozygote and dominant genetic models (C vs T: OR=0.88, 95%CI 0.81-0.95, p=0.002; TC vs TT: OR=0.85, 95%CI 0.77-0.93, p=0.001; CC/TC vs TT: OR=0.86, 95%CI 0.78-0.94, p=0.001). In the subgroup analysis by ethnicity, a significantly decreased cancer risk was found in Asian but not Caucasian populations. Conclusions: The present meta-analysis suggests that the C allele of the DICER rs1057035 polymorphism probably decreases cancer risk. However, this association may be Asian-specific and the results should be treated with caution. Further well-designed studies based on larger sample sizes and group of populations are needed to validate these findings.
This paper presents some quasi-static tests for 4 mixed columns composed of CFST column and RC column. The seismic performance and failure mode were studied under low-cyclic revised loading. The failure mode was observed under different axial compression ratios. The hysteretic curve and skeleton curve were obtained. The effects of axial compression ratio on yield mechanism, displacement ductility, energy dissipation, stiffness and strength attenuation were analyzed. The results indicate that the failure behavior of CFST-RC mixed column with archaized style is mainly caused by bending failure and accompanied by some shear failure. The axial compression ratio performs a control function on the yielding order of the upper and lower columns. The yielding mechanism has a great influence on the ductility and energy dissipation capacity of specimens. Based on the experiment, finite element analysis was made to further research the seismic performance by ABAQUS software. The variable parameters were stiffness ratio of upper and lower columns, axial compression ratio, yielding strength of steel tube, concrete strength and rebar ratio. The simulation results show that with the increase of stiffness ratio of the upper and lower columns, the bearing capacity and ductility of specimens can correspondingly increase. As the axial compression ratio increases, the ductility of the specimen decreases gradually. The other three parameters both have positive effect on the bearing capacity but have negative effect on the ductility. The results can provide reference for the design and engineering application of mixed column consisted of CFST-RC in Chinese archaized buildings.
Proceedings of the Korean Society of Propulsion Engineers Conference
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2008.03a
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pp.130-135
/
2008
An aerodynamic optimization design process of multistage axial turbine is presented in this article: first, applying quasi-three dimensional(Q3D) design methods to conduct preliminary design and then adopting modern optimization design methods to implement multistage local optimization. Quasi-three dimensional(Q3D) design methods, which mainly refer to S2 flow surface direct problem calculation, adopt the S2 flow surface direct problem calculation program of Harbin Institute of Technology. Multistage local optimization adopts the software of Numeca/Design3D, which jointly adopts genetic algorithm and artificial neural network. The major principle of the methodology is that the successive design evaluation is performed by using an artificial neural network instead of a flow solver and the genetic algorithms may be used in an efficient way. Flow computation applies three-dimensional viscosity Navier Stokes(N-S) equation solver. Such optimization process has three features: (i) local optimization based on aerodynamic performance of every cascade; (ii) several times of optimizations being performed to every cascade; and (iii) alternate use of coarse grid and fine grid. Such process was applied to optimize a three-stage axial turbine. During the optimization, blade shape and meridional channel were respectively optimized. Through optimization, the total efficiency increased 1.3% and total power increased 2.4% while total flow rate only slightly changed. Therefore, the total performance was improved and the design objective was achieved. The preliminary design makes use of quasi-three dimensional(Q3D) design methods to achieve most reasonable parameter distribution so as to preliminarily enhance total performance. Then total performance will be further improved by adopting multistage local optimization design. Thus the design objective will be successfully achieved without huge expenditure of manpower and calculation time. Therefore, such optimization design process may be efficiently applied to the aerodynamic design optimization of multistage axial turbine.
Objective: Intramuscular fat (IMF) content plays an important role in meat quality. Identification of single nucleotide polymorphisms (SNPs) and genes related to pig IMF, especially using pig populations with high IMF content variation, can help to establish novel molecular breeding tools for optimizing IMF in pork and unveil the mechanisms that underlie fat metabolism. Methods: We collected muscle samples of 453 Chinese Lulai black pigs, measured IMF content by Soxhlet petroleum-ether extraction method, and genotyped genome-wide SNPs using GeneSeek Genomic Profiler Porcine HD BeadChip. Then a genome-wide association study was performed using a linear mixed model implemented in the GEMMA software. Results: A total of 43 SNPs were identified to be significantly associated with IMF content by the cutoff p<0.001. Among these significant SNPs, the greatest number of SNPs (n = 19) were detected on Chr.9, and two linkage disequilibrium blocks were formed among them. Additionally, 17 significant SNPs are mapped to previously reported quantitative trait loci (QTLs) of IMF and confirmed previous QTLs studies. Forty-two annotated genes centering these significant SNPs were obtained from Ensembl database. Overrepresentation test of pathways and gene ontology (GO) terms revealed some enriched reactome pathways and GO terms, which mainly involved regulation of basic material transport, energy metabolic process and signaling pathway. Conclusion: These findings improve our understanding of the genetic architecture of IMF content in pork and facilitate the follow-up study of fine-mapping genes that influence fat deposition in muscle.
Journal of the Korea Society of Computer and Information
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v.26
no.8
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pp.229-237
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2021
This paper aims to study the using motivation and influencing factors of Chinese users' participation in live stream shopping through theoretical and empirical analysis, so as to evaluate the change in users' needs and improve marketing strategies. In doing so, I conducted a questionnaire survey for Chinese live stream shopping users and collected the required data. For empirical analysis, I used SPSS and AMOS software to carry out descriptive analysis, reliability and validity analysis and structural equation model analysis (SEM) to test the hypothesis. The results of the analysis showed that core competency and brand personality of the short video industry have a significant impact on user and customer perceived value, thus influencing users' using motivation. That is, users do not blindly follow live stream shopping but make their active choice. Therefore, it is suggested that live stream shopping platform should strengthen the e-commerce attributes and eradicate "the sense of false satisfaction", in order to achieve the effective communication of information. On the other hand, to stimulate the purchase motivation of users, the brand should build up its personality, and enhance user and customer perceived value in cyber marketing.
The price-to-earnings ratio (PER) is an important indicator to measure the stock price and profitability of a firm; it is also the most used valuation indicator among investors. When using the PER to compare the investment values of different stocks, these stocks must come from the same sector. This study mainly focuses on the China's listed manufacturing firms. By learning from previous research results and analyzing the current situation, we studied the correlation between the manufacturing sector's PER and its influencing factors from both macro and micro perspectives, the combination of which eventually sheds light on such correlation. Analyzing GDP growth rate data, Manufacturing Purchasing Managers' Index, and other macroeconomic variables from 2008 to 2018, we conclude that these variables jointly have a certain impact on the average PER of the manufacturing sector. We then form panel data based on relevant (2014-2018) data gathered from 317 of China's A-listed manufacturing firms to study the impact of micro-variables on PER. By using Stata and other software to analyze the panel data, we reach the conclusion that the Debt to Asset Ratio, Return on Equity, EPS growth rate, Operating Profit Ratio, Dividend Payout Ratio, and firm size have a significant impact on PER. The Current Ratio, Treasury Stock ratio and Ownership Concentration have no distinct effect on PER. Based on our empirical findings, we design a theoretical model that affects the PER.
Purpose - The Chinese fan community includes a significant number of young and middle-aged individuals, playing a crucial role in emotional mobilization and social engagement. In recent years, the impact of Celebrity Pairing or Character Pairing (CP) on Weibo has grown notably, partly due to features like Super Topics and Hot Searches. This phenomenon has enhanced fan engagement, resulting in heightened participation in discussions and interactions on the platform. Our study targets CP fans of movies and television dramas on Weibo and aims to identify the factors that drive their emotional sharing. Design/methodology/approach - The research methodology integrates Self-Determination Theory and Social Sharing of Emotion Theory within the EASI (Emotion, Attachment, and Social Integration) model. This approach aims to uncover how CP fans meet their emotional needs via social media and determine the factors influencing their sharing intentions and behaviours. Data were collected through online surveys, yielding 504 valid responses Findings - The analysis, performed with SPSS and Smart PLS software, reveals that self-determination, interpersonal relationships, and social media tolerance significantly affect fans' intentions to share content. Specifically, intrinsic motivation, driven by self-determination, is a critical factor in CP fans' propensity to share content, highlighting the importance of 'inward socialization.' Additionally, the study finds that external factors, like the social media environment, play a more minor role than internal motivators. Research implications or Originality - This research enhances quantitative research methodologies by identifying intrinsic and extrinsic motivations that satisfy the emotional needs of CP fans. It distinguishes between individual, interpersonal, and collective/social factors as motivational elements, providing insights into the emotional and psychological needs of the Chinese movie and TV drama fan community.
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