• Asian Pacific Journal of Cancer Prevention
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• v.14 no.10
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• pp.5645-5650
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• 2013

Src homology 2 domain containing (SHC) is a proto-oncogene which mediates cell proliferation and carcinogenesis in human carcinomas. Here, the SHC SH2-domain binding protein 1 (SHCBP1) was first established to be up-regulated in human hepatocellular carcinoma (HCC) tissues by array-base comparative genome hybridization (aCGH). Meanwhile, we examine and verify it by quantitative real-time PCR and western blot. Our current data show that SHCBP1 was up-regulated in HCC tissues. Overexpression of SHCBP1 could significantly promote HCC cell proliferation, survival and colony formation in HCC cell lines. Furthermore, knockdown of SHCBP1 induced cell cycle delay and suppressed cell proliferation. Furthermore, SHCBP1 could regulate the expression of activate extracellular signal-regulated kinase 1/2 (ERK1/2) and cyclin D1. Together, our findings indicate that SHCBP1 may contribute to human hepatocellular carcinoma by promoting cell proliferation and may serve as a molecular target of cancer therapy.

• Journal of Koreanology Reviews
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• v.1 no.1
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• pp.37-49
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• 2022

The purpose of this study is to discuss how Dongi People in ancient societies resided in the region including the Korean Peninsula shaped its economy, what kind of currency was used, and their economic activities using this currency. This study started from a skeptical point of view that the Dongi People were conducting economic activities with the currency used in the country made by the Jina People before and after the Gojoseon society. Currently, in China, all currencies issued in China are treated as their own currency. It is due to subjective interpretation from a nationalist point of view. Japan subjectively interprets and judges from a Japanese point of view and North Korea judges from the central point of view on the Korean Peninsula. This difference is due to the subjective interpretation from the researcher which has been affected by their associating academic area. This has caused the lack of objectivity. In other words, it means that there is a big difference in the perception of the interpretation of history between different academic areas. This study, therefore, tried to avoid the application of biased concept or academic research in order to define the distribution economics more objectively by conducting the study based on the literature sources from Chinese ancient books and field research materials as much as possible, as the study and research conducted based on the domestic sources are insufficient in the sense that there is a gap between different perceptions and interpretations. As a conclusion of this study, the excavation area of Myeong-do-jeon is perfectly consistent with the old river area of Gojoseon, and in particular, considering Gojoseon was in the hostile relationship with Yan, it was found that only Myeong-do-jeon was used without using any other Chinese currency in the entire Gojoseon area, not just some areas. It is also a decisive clue to prove that it is not the Yan currency. The limitation of this study in developing the discussion different from the current research and study is that there was a lack of exploration and investigation of various documents and relics. For future research, this study will become more meaningful when it is conducted simultaneously with the discovering of new documents as well as the relics.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.1749-1752
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• 2012

Colorectal cancer (CRC), now the third most common cancer across the world, is known to aggregate in families. USP7 is a very important protein with an important role in regulating the p53 pathway, which is critical for genomic stability and tumor suppression. We here genotyped eight SNPs within the USP7 gene and conducted a case-control study in 312 CRC patients and 270 healthy subjects in the Chinese Han population. No significant associations were found for any single SNP and CRC risk. Our data eliminate USP7 as a potential candidate gene towards for CRC in the Han Chinese population.

• Journal of the Korean Applied Science and Technology
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• v.37 no.5
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• pp.1441-1453
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• 2020

The purpose of this study was to compare acne recognition and management methods for those in their 20s and 30s who live in China and have acne. A total of 600 questionnaires were distributed and 533 copies were used for final analysis, excluding 27 of the 560 collected questionnaires. As a result of the study, the difference in perception of the cause of acne, management perception, and exacerbation factor of Chinese people according to age showed'management perception' t=3.380, and deteriorating factor recognition' t=2.314, indicating that there was a difference in perception of acne according to age. It was found that the recognition degree of acne is higher in the 20s than in the 30s. Through this study, by comparing and analyzing the perceptions and management methods of acne according to the age of Chinese people, the changes in acne management perception and behavior according to the change of the times were identified, and the difference between Korean and Chinese perceptions of acne, and later acne skin It is believed that it can be provided as a basic data for finding an effective management method.

• Korean journal of communication and information
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• v.62
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• pp.74-94
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• 2013

The purpose of the thesis is to find out the correlation between Chinese 'Personal Opinion Expression on Offline' and 'Personal Opinion Expression on Online'(Hypothesis 1) and between 'Save Face' and 'Personal Opinion Expression on Offline', 'Personal Opinion Expression on Online'(Hypothesis 2). It also analyzes and verifies the impact of 'Save Face' among 'Personal Opinion Expression on Offline', and 'Personal Opinion Expression on Online'(Hypothesis 3). The results of this study shows that correlation between 'behavior of opinion expression on Offline' and 'behavior of opinion expression on Online'. Chinese people who express their views in the public, tend to express their opinions on the Online. The thesis also covers that 'Silence' can be caused not only by 'Personal Fear of Isolation', but also by 'Save Face' upon 'The Spiral of Silence a Theory' by Elisabeth Noelle-Neumann, and prove that 'Save Face' relatively affects 'People talk about their observation'. It also confirms that 'Save Face in Open Space', a factor of 'Save Face's, performs a partial channel on 'Personal Opinion Expression on Online' and 'Personal Opinion Expression on Offline'.

• The Bulletin of The Korean Astronomical Society
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• v.37 no.1
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• pp.52.1-52.1
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• 2012

It is often said that there is little geometrical mind in Korean history. However, a method to project the surface of a sphere onto 2-dimensional plain was applied to the representative Korean star chart or Cheonsang Yeolcha Bunyajido (天象列次分野之圖). The method, called the equi-distant polar projection, was explained in detail in ancient Chinese history book of the Tang dynasty, which was originated from older history. Another method of the Mercator projection was introduced by the famous engineer Su Song (蘇頌) of the Song dynasty. The description has quite geometrical thoughts, especially the concept of infinity or convergence appears, However, this type of sky projection method was not widely used in east Asia. When the European Jesuits came to China to evangelize the Chinese people, they found that the Chinese people paid much attention to advanced European astronomical knowledge. Thus, they introduced the European astronomical knowledges into China, and the star chart was one of them. The projection method of the new charts were quite different from the Chinese tradition. When the Koreans brought those new star chart from China, they must have known the geometrical description of the method. The method was described in detail in a volume of Chongzhen Lishi (崇禎曆書) or Xiyang Xinfa Lishu (西洋新法曆書). The explanation consists of three part. One is the quantitative way; another is a geometrical way using axiomatic systems; and the other is the practical method to draw star chart with the geometical projection. However, when we see the Honcheon Jeondo (渾天全圖) that is thought to be duplicated by Kim Jeongho (金正浩), the new geometrical method was not so widely known to the Koreans. I will discuss the reason why the geometrical minds have not been widely adopted in the Korean civilization.

• Journal of the Korean Society of Costume
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• v.36
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• pp.77-95
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• 1998

The culture of a country is formed by the sense of value of a nation being a creator as well as on operator of the culture. So, the Chinese culture and fruthermore, the sense of value the Chinese people can be understood through the study of the costume of China. Above all, the culture of China, including the costume, have been formed through the his-tory of exchange between the central Chinese people and its surrounding minority races, and it should not be overlooked that its own culture of each race is existing with each other in the great Chinese culture sphere. In the paper, the concept of costume as relections of a culture is confirmed through the examination of the characteristics of the costume of the Miao tribe with such history and culture as a background and on effort is made to take those as resources modern fashion designs while inferring from them the characteristics of costume with universal and original values sthat can be sublimated into the modernistic beauty. The results of the study are as follows. First, the basic composition consists of a simple jacket made in a way of straight-cut-ting and a close pleated skirt and it tended to put emphasis on diversified and splendid decorations compared with the simple basis composition. Second, the costume of the Miao tribe are characteristic of hair done in a knot with head-dress around head. Third, the kinds of dress are multifarious by race and region due to a long period of mobile and disperse life. In the course of studying the universal value of the Miao tribe is confirmed which is by no means inferior to the standard of the medernistic beauty which keeping its originality. The study is made to be helpful for activating the design going with the trend that the basic harmony between the nature and man, that is a climate and the local cul-ture hearing formed a splendid culture in the past, are being found again.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.5241-5243
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• 2012

Background: Prostate cancer (Pca) is one of the most common complex and polygenic diseases in men. The X-ray repair complementing group 1 gene (XRCC1) is an important candidate in the pathogenesis of Pca. The purpose of this study was to evaluate the association between single nucleotide polymorphisms in the XRCC1 gene and susceptibility to Pca. Materials and Methods: XRCC1 gene polymorphisms and associations with susceptibility to Pca were investigated in 193 prostate patients and 188 cancer-free Chinese men. Results: The c.910A>G variant in the exon9 of XRCC1 gene could be detected by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and DNA sequencing methods. Significantly increased susceptibility to prostate cancer was noted in the homozygote comparison (GG versus AA: OR=2.95, 95% CI 1.46-5.42, ${\chi}^2$=12.36, P=0.001), heterozygote comparison (AG versus AA: OR=1.76, 95% CI 1.12-2.51, ${\chi}^2$=4.04, P=0.045), dominant model (GG/AG versus AA: OR=1.93, 95% CI 1.19-2.97, ${\chi}^2$=9.12, P=0.003), recessive model (GG versus AG+AA: OR=2.17, 95% CI 1.33-4.06, ${\chi}^2$=8.86, P=0.003) and with allele contrast (G versus A: OR=1.89, 95% CI 1.56-2.42, ${\chi}^2$=14.67, P<0.000). Conclusions: These findings suggest that the c.910A>G polymorphism of the XRCC1 gene is associated with susceptibility to Pca in Chinese men, the G-allele conferring higher risk.

• The Journal of the Korea Contents Association
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• v.14 no.9
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• pp.218-226
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• 2014

China has become a G-2 Superpower country as result of rapid economic growth through the reform and opening-up in these days. It expressed its confidence by helding a few big international events, such as Bejing Olympic Games. Shanghai Expo. Though most Chinese people give their agreement and support to the government, there are serious, ill-concealed political problems behind the curtain in China. As a multi-ethnic nation, China has repeated experience of fragmentation and integration of various ethnic groups through her long history. In spite of top-level political leaders of communist party always concern the issues of separatism very sensitively, China has suffered occasional bloodshed terrorism because of erupting ethnic and religious conflicts. Especially there are many disruption and fear due to the bloodshed and terrorism by a minority race-seperatists of Uighur tribe in Xinjiang province. The Uighur in Xinjiang province is very different from major Chinese Han ethnically and culturally. Although Chinese government has presented various policies in order to suppress the Uighus's desire for seperation, they have not been able to offer a fundamental, satisfying solution. Because we, Korean people face the expansion of possibility of conflicts, such as increasing of foreign workers, multi-cultural families and extremists. At this point, I believe we can learn valuable lessons from Chinese experiences for anti-terrorism.

• Fashion & Textile Research Journal
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• v.7 no.5
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• pp.481-493
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• 2005

Reason for contemporary ethnic-look's remarkable world popularity is viewed as due to counteraction of disordered world conditions such as war, terror, and economic depression. These conditions led people to desire the returning to primitive human society where freedom and peace are preserved. The background of ethnic look emergence is influences of post-modernism, eastern and western culture hybrid, and ecology. This study will mainly focus on the analysis of present ethnic fashion trend and, with following to this, their images will be analyzed and categorized. The result of ethnic trend, especially that of Asian's and African's, from 2000 to 2005 is like this: representative Asian ethnic fashion tendency is focusing on Japanese and Chinese. In Japanese style, oversized silhouette was derived by Kimono and wide belt was appeared by influence of Kimono's Obi. Chinese ethic style are analyzed as adapting feministic silhouette and details from Chinese traditional clothes, Chipao. Additionally, in some of the Chinese ethnic-look, there are mixtures with Japanese, North American, and African's images. Mixing with pop images and ancient ones are also emerged. In the African ethnic look, people used colorful cloth and new materials which is considered as integration of primitives and modern science. From the study, it is possible to conclude that current modern ethnic fashion can be defined as blends with one country's image to the other, mixture with new technology, and acceptance to the multi-national folk fashion. These trends are widely revealed and extended in the world fashion. In the following result of the analysis, there were four outstanding images lying underneath in the present ethnic-look. That is eclectic, traditional, natural, and mysterious images.