• 동의생리병리학회지
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• 제27권1호
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• pp.34-42
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• 2013

Our study is to review Chinese traditional medicine's journals about the diagnosis and treatment of spasmodic torticollis such as category, syndrome differentiation, acupoints of treatment, and herbal medicine. The journal search was performed using the search engine of China Academic Journal (CAJ) and China Doctor/Master's Dissertation (CDMD) in China National Knowledge Infrastructure (CNKI) from January 1982 to October 2012. Searching key words were the diverse combination of "spasmodic torticollis", "cervical dystonia", "Chinese traditonal medicine", "herbal medicine", "acupuncture", and "syndrome differentiation". The inclusion criteria was all kinds of journals including Chinese traditional medicine approach except for experiment study. The category, syndrome differentiation, acupoints of treatment, and herbal medicine from finally selected journals were extracted and summarized. The fourty-seven Chinese journals were selected finally. The category was divided into wind syndrome, trembling syndrome, convulsive syndrome, and convulsions. The syndrome differentiation was classified as internal stirring of liver wind, yin-blood depletion, invasion of external contraction, uncontrol of governor vessel, internal obstruction of phlegm turbidity, dual deficiency of qi and blood, and blood stasis due to qi stagnation. The combination of acupoints to unblock the meridian and dissipate binds and to tonify governor vessel and repel tremor was mainly used in acupuncture treatment. Galgun-tang or galgun-tanggami was primarily used and the others were the prescriptions to tonify liver and kidney, to calm convulsion, and to dispeling wind-phlegm. We suggests that spasmodic torticollis could be treated using Korean medicine's approach in Korea.

• 한국미생물·생명공학회지
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• 제45권1호
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• pp.71-80
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• 2017

차는 세계적으로 인기있는 음료로서, 그 종류는 불발효차(녹차), 반발효차(우롱차), 완전발효차(홍차), 후발효차 등으로 구분된다. 후발효차는 차나무(Camellia sinensis)의 잎을 미생물 발효과정을 거쳐 생산된다. 본 연구에서 한국 후발효차(알가차, 단차)와 중국 후발효차(보이차 2종)에 우점하는 미생물 분석을 위해 16S rRNA 유전자를 이용하였다. 후발효차에 우점하는 미생물은 ${\alpha}$-proteobacteria에 속하는 Rhodobacteraceae와 Sphingomonas, ${\gamma}$-proteobacteria에 속하는 Pantoea가 우점하였다. 미생물 군집 cluster 분석결과, 한국 후발효차와 중국 후발효차는 다르게 분류됨을 확인하였다. 또한, 매우 흥미롭게도 한국 후발효차는 미생물이 우점하였고 중국 후발효차는 곰팡이가 우점하는 것으로 분석되었다.

• 동의생리병리학회지
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• 제30권4호
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• pp.209-218
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• 2016

The objective of this study was to investigate the diagnosis and treatment of Retinal vein occlusion such as syndrome differentiation and herbal medicine by reviewing Chinese traditional medicine`s journals. The journal search was carried out using China National Knowledge Infrastructure and Pubmed from January 2000 to December 2014. Searching key words were the various combination of "Retinal vein occlusion", "traditional chinese medicine", "syndrome differentiation". The final selection of 11 studies were selected and summarized by researchers. The effective rate was significantly higher than control but, methodological quality of the trials was generally low questioning their liability. The syndrome differentiation was classified as hyperactivity of liver yang and blood stasis. The most frequently prescribed herbal medication was Hyulbuchookeotang, Boyanghwanotang and Cheomagudeungum. This finding could be widely utilized in future clinical practice and form the basis for the development of clinical practice guidelines in advance.

• 생약학회지
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• 제42권2호
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• pp.187-194
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• 2011

Aldose reductase (AR), the key enzyme in the polyol pathway, plays an important role in the development of the diabetic complications. None of Aldose reductase Inhibitor (ARI) has achieved worldwide use because of limited efficacy or undesirable side effects. Therefore, evaluating natural sources for ARI potential may lead to the development of safer and more effective agents against diabetic complications. Fifty two Chinese herbal medicines have been investigated for inhibitory activities on AR. Among them, twelve herbal medicines, Artemisia anomala (aerial part), Centella asiatica (aerial part), Scutellaria baicalensis (root), Senecio chrysanthermoides (whole plant), Gleditsia japonica (twig), Zizyphus jujube (twig, leaf), Citrus aurantium (fruit), Hydnocarpus anthelmintica (fruit), Potaninia mongolica (aerial part), Tribulus terrestris (fruit), Artemisia apiacea (aerial part) and Eclipta prostrate (aerial part) exhibited a significant inhibitory activity against AR. Particularly, Artemisia anomala, Centella asiatica and Scutellaria baicalensis showed four times more potent inhibitory activity than the positive control, 3,3-tetramethyleneglutaric acid (TMG).

• 대한예방한의학회지
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• 제25권3호
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• pp.39-55
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• 2021

Objective : To investigate specific prescriptions, herbal medicines and treatment strategy, this study systematically reviewed case studies on traditional Chinese medicine (TCM) treatment for childhood cancer. Method : Literature searches were performed on database of China National Knowledge Infrastructure (CNKI). Studies published before December 2020 were categorized and analyzed according to the treatment strategy and we also investigated Chinese herbs used in the prescriptions. Results : Twenty-five studies including 17 case series and 8 single case reports were included in our review. Of the total 439 patients, 379 (85.7%) had leukemia and other myeloplastic disease. Conventional western medicine (CWM) treatment was also used with TCM based on the syndrome identification. Most studies reported favorable effect of combination treatment with CWM and TCM. Among 266 herbs in the studies, reinforcing herbs were more frequently used than anti-cancer herbs. Conclusion : Traditional herbal treatment for childhood cancer should be performed considering the syndrome identification as well as stage of CWM. Reinforcing herbs should be more focused because of the fragility and growth of the childhood.

• 동의신경정신과학회지
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• 제23권2호
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• pp.1-12
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• 2012

Objectives : This study is set out to discover more about the treatment of anxiety disorder in Traditional Chinese Medicine. Methods : We searched the database-China Academic Journals(CAJ). For papers published since 2007-2011, which are classified in categories. Results : We have finally selected 23 articles, and the results were as follows: 1. Stages of Anxiety disorder are discussed in various aspects. 2. Diagnostic criteria and evaluation criteria were the same, especially, in the CCMD and HAMA was used most frequently. Adverse effects were reported using TESS. 3. There are various ways, such as Herbal medicine, acupuncture, electroacupuncture stimulation, acupoints injection, and abdominal massage therapy to treat Anxiety disorders in TCM. 4. Zizyphus jujuba, Poligala tenuifolia, Poria cocos are mainly used in herbal medicine. Sinmun(HT7), Sameumgyo(SP6), Naegwan(PC6) are mainly used in acupuncture points. 5. The treatment group, cured by herbal medicine or acupuncture, was similar in its therapeutic efficiency to that of the control group, which was cured by western medicine. In some cases, the treatment group was better off than the control group. Herbal medicines have been reported that they have less side effects and drug addiction than the western medicines. We predict that herbal medicine in the treatment for anxiety disorders will have an advantage. Conclusions : There are a wide range of approaches in the treatments for Anxiety disorders in TCM. In some aspects, herbal medicine is more effective than that of the western medicine. According to this study, we predict that herbal medicine in the treatment for anxiety disorders, has some advantage. Therefore, there is a need for more clinical research for this disorder in Korean traditional medicine.

• 대한한방소아과학회지
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• 제35권4호
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• pp.125-140
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• 2021

Objectives This study aims to find out the recent trend of the herbal medicine treatment in children's stomatitis in China, and propose better methods to treat children's stomatitis in Korea. Methods The randomized controlled trials (RCT) relevant to 'Herbal medicine treatment on children's stomatitis' were searched using China Academic Journal (CAJ). The search method we used included search formula, (SU = '口內炎' + '口腔炎' + 'stomatitis') and (SU = '儿童' + '小儿' + 'children' + 'child') from 2000 to September 2021. Results A total of 9 RCTs were selected and analyzed. All reports showed that oral administration of herbal medicine were effective and improved clinical symptoms. The most-used herbal medicine category was Heat-clearing medicine (淸熱藥). Conclusions The literatures from China have shown that herbal medicine improves children's stomatitis. These outcomes may be helpful for the treatment of children's stomatitis in Korea. However, further studies are needed to develop treatment guidelines for children's stomatitis.

• 대한한방소아과학회지
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• 제32권2호
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• pp.26-42
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• 2018

Objectives The purpose of this study is to figure out the recent trend of the treatment for autism spectrum disorder (ASD) by comparing Korean and Chinese clinical studies. Methods National Digital Science Library (NDSL), Oriental medicine Advanced Searching Integrated System (OASIS), Research Information Sharing Service (RISS) and Korean Traditional Knowledge Portal (KTKP) were used to search Korean studies which were published from January, 2011 to May, 2017. Also Chinese National Knowledge Infrastructure (CNKI) and Wanfang data were used to search Chinese studies which were published from the same period. Key words of 'Autism' and 'Autism spectrum disorder' were used. Results 3 Korean studies and 21 Chinese studies were selected and analyzed to find out the most commonly used diagnostic criteria, treatments, including herbal medicine and acupuncture, and treatment assessment procedures. Conclusions As a result of comparing Korean and Chinese clinical studies for the treatment of ASD, both Korean and Chinese medicine treatments showed their effectiveness. However, there were some differences between two countries' clinical trends. In order for this study to be helpful, more highly evidenced clinical studies should be followed.

• 원예과학기술지
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• 제33권6호
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• pp.820-828
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• 2015

본 연구는 여름철 배추재배시 안정적인 생산을 위한 몇가지 조건을 알아보기 위하여 춘화처리, 재배 기간 동안 온도처리, 토양수분 결핍 처리에 따른 배추의 엽육조직, 생장 및 수량에 미치는 영향을 구명하고자 실시하였다. 토양수분 결핍 2주 처리구에서는 울타리조직과 해면조직의 세포구조를 확인할 수 있었으나, 토양수분 결핍 4주 처리구에서는 세포조직이 완전히 붕괴되었다. 토양수분 결핍 처리가 가장 배추의 생장에 통계적으로 유의하게 영향을 크게 미쳤고, 배추의 생장은 토양수분 결핍 4주 처리구들에서 전반적으로 낮은 경향을 보였다. 토양수분 결핍처리는 배추의 상대생장률, 단위 엽건물중 증가율, 엽면적비율 및 비엽중, 및 엽중률에서 통계적으로 유의하게 효과가 인정되었다. 배추의 수량은 춘화처리 후 고온에서 충분히 관수한 처리구에서 가장 많았으며, 토양수분 결핍 4주 처리구들의 수량이 다른 처리구들에 비하여 유의하게 적었다. 배추 수확시 결구력은 토양수분 결핍 처리구에서 중이하로 나타나 심한 가뭄에 의한 식물체내 수분 부족은 결구력을 약화시키는 것으로 나타났다. 배추에서 문제가 되는 추대는 정식 초기에 저온처리후 고온으로 관리하여도 추대가 발생하지 않았다. 여름철 고온기 배추재배시 2주 동안 가뭄이 지속되면 엽육조직이 붕괴가 시작되고 생장이 지연되어 수확량이 줄어들기 때문에 적극적으로 관수해야 할 것으로 판단된다.

• Asian-Australasian Journal of Animal Sciences
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• 제23권6호
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• pp.750-756
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• 2010

Two trials were conducted to study the effects of two Chinese herbal polysaccharides, Astragalus polysaccharides (APS) and Achyranthes bidentata polysaccharides (ABPS), and one Chinese herbal saponin, Acantbepanax senticosus saponin (ASS), on the immunity and growth performance of weaned pigs. Experiment 1 was a 14-day growth assay, in which 32 weaned pigs were randomly allocated to one of four dietary treatments: i) 0.05% talcum powder control; ii) 0.05% APS; iii) 0.05% mixture of APS and ASS in a 1:1 ratio by weight; and iv) 0.05% mixture of APS, ASS, and ABPS in a ratio of 1:1:1 by weight. Blood samples were collected on day 14 to determine plasma parameters. Feed intake, body weight gain, and feed efficiency were also determined. Experiment 2 was a 21-day immunity assay, in which 16 weaned pigs were randomly allotted to one of two dietary treatments: i) 0.05% talcum powder control; and ii) 0.05% mixture of APS and ASS in a 1:1 ratio by weight. On day 21, pigs were challenged with lipopolysaccharide (LPS) and 3 h later blood samples were collected and analyzed for lymphocyte proliferation as well as interleukin 6 (IL-6), insulin-like growth factor 1 (IGF-1), growth hormone (GH), and cortisol levels. In Experiment 1, feeding Chinese herbal polysaccharides and saponin increased growth performance of the pigs. The effects of the mixture of APS and ASS were especially notable, as there was a significant improvement in growth performance compared with the control (p<0.05). The plasma concentration of immunoglobulin G (IgG), nitric oxide (NO), and nitric oxide synthase (NOS) were increased in all treatments groups, with the mixture of APS and ASS increasing the level of IgG and NOS significantly (p<0.05), compared with the control. There was no difference in the NO level between the control and treatment groups (p>0.05). In Experiment 2, Chinese herbal polysaccharides and saponin showed immunostimulating effects. The level of cortisol, GH, and IGF-I were significantly increased (p>0.05), and the level of IL-6 showed a significant decrease (p<0.05) in the APS and ASS treatment after the LPS challenge. The mixture of APS and ASS could stimulate the blood lymphocyte proliferation significantly whether the LPS was injected or not (p<0.05). These results show that Chinese herbal extracts can improve growth performance and stimulate immunity of weaned pigs. A mixture of APS and ASS, compared with APS alone, could be a new kind of immunostimulant for weaned pigs, which could result in greater positive effects on their growth performance and immunity.