• Korean Journal of Pharmacognosy
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• v.45 no.4
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• pp.359-365
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• 2014

Aldose reductase (AR) is the key enzyme of the polyol pathway in the development of the diabetic complications. Sixty seven Chinese herbal medicines have been investigated for inhibitory activities on AR. Among them, 7 herbal medicines, Buddleja crispa (twigs and leaves), Taiwania flousiana (twigs and leaves), Sloanea hemsleyana (fruits), Euphorbia nemetocypha (whole plants), Photinia glomerata (twigs and leaves), Vitex yunnanensis (twigs and leaves) exhibited a significant inhibitory activity against AR. Particularly, S. hemsleyana and V. yunnanensis showed 1.2-4.5 times more potent inhibitory activity than the positive control, 3,3-tetramethyleneglutaric acid (TMG).

• Advances in Traditional Medicine
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• v.7 no.3
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• pp.211-216
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• 2007

Swollen and painful extremities have been treated with herbal baths in attempts to alleviate the symptoms. A popular herbal bath used in China, contains a component called 'bone-penetrating herb' which is believed to facilitate the penetration of herbal substances across the skin to the swollen site, so swollen site, so that pain and swelling will be improved. A search from the Chinese pharmacopedia revealed that 22 different herbs have been traditionally used as 'bone-penetrating herb'. Five of these herbs were available in market and were chosen for experimental studies. Standard diffusion experiments were done to identify the most effective herb among the five, in the penetration facilitation. Glechoma longituba at a concentration of 20% was found to give the best results in the facilitation of Bromophenol blue diffusion across artificial and biological membranes. When compared with one commonly used diffusion facilitator, viz. azone, azone was found to be more effective than glechoma longituba. The encouraging observations support future studies on the basic science behind the use of herbal components as topical agents to treat pain and swelling.

• Research in Plant Disease
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• v.22 no.3
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• pp.194-197
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• 2016

Chinese yam necrotic mosaic virus (CYNMV) is one of the most widespread viruses in Chinese yam (Dioscorea opposita Thunb.) and causes serious yield losses. Currently, genetic information of CYNMV is very restricted and complete genome sequences of only two isolates (one from Japan and another from China) have been reported. In this study, we determined complete genome sequence of the CYNMV isolate AD collected from Andong, Korea. Genetic analysis of the polyprotein amino acid sequence revealed that the Korean isolate AD has high similarity with the Japanese isolate PES3 (97%) but relatively low similarity with the Chinese isolate FX1 (78%). Phylogenetic analysis using the CYNMV 3' proximal nucleotide sequences harboring the coat protein and 3' untranslated region further supported genetic relationship among the CYNMV isolates. Based on comparative analysis of the CYNMV genome sequences determined in this study and other previous studies, we generated molecular detection primers that are highly specific and efficient for CYNMV diagnosis.

• Journal of Oriental Neuropsychiatry
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• v.19 no.2
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• pp.141-149
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• 2008

Objective : This study was designed to analyze the herbal medicine case-control studies of tic disorder in traditional chinese medicine. Method : For this study, we searched the studies on tic disorder, which had been published 2007, through web-site CNKI(中國知識基魔設施工程) http://www.cnki.net). There were 15 herbal medicine case-control studies and we focused on those studies. Results: 1. DSM-IV(7 studies), CCMD(5 studies) and ICD-10(3 studies) were frequently used in the diagnosis of tic disorder. 2. Paeonia radix alba, Uncariae ramulus et uncus and Glycyrrhizae radix were frequently used in treatment. Moreover Scorpio, Gastrodiae rhizoma, Pinelliae rhizoma and so on were used. 3. Treatment results were assessed by improvement of symptom, YGTSS and so on. 4. Herbal medicine treatment was more effective than western medicine treatment in most studies, and side effects of herbal medicine were far less than those of western medicine. Conclusion : There have been reported many herbal medicine treatment studies of tic disorder in traditional chinese medicine. We believe that these studies can be applied to the clinical practices in Korean medicine.

• The Journal of Korean Medicine
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• v.28 no.1 s.69
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• pp.117-125
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• 2007

Objectives : This study was to assess the Traditional chinese medicine forecast subjects that had been expected to be accomplished over 20 year (1990-2010). The result will help Korea medical society to compare the status of Korean Medicine with that of Traditional Chinese Medicine and to plan for polices and studies on Korean Traditional Medicine. Methods : Assessed targets were the subjects selected by the China Academy of Chinese Medical Sciences, which are classified into 6 fields. These were assigned by the quantity of related theses. Reference source is CAJ（China academic Journal) of CNKI (China National Knowledge infrastructure). Results : 1) Forecast subject ratio by field was basic theory 31% / clinical research 17% / Chinese herbal drug 17% / acupuncture and moxa 17% / Tui-na(推拿) and Qi-gong(氣功) 9% / medical information, literature history 6%. 2) Accomplishment percentage (full accomplishment) by field was medical information, literature, history 60% / basic theory 50% / acupuncture and moxa 46% Tui-na(推拿) and Qi-gong(氣功) 38% / chinese herbal drug 25% / clinical research 23%. Conclusions : 78% of all forecast subjects were accomplished or partially accomplished. According to 'accomplishment percentage by field', while those in the medical information, literature, history field were most realized of all, those in the clinical research field were least realized.

• Journal of Physiology & Pathology in Korean Medicine
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• v.35 no.6
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• pp.219-227
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• 2021

The purpose of this study is to analyze the side effects (ADR) of Traditional Chinese Medicine (TCM) injections by age, injection type, symptoms, and causes, and to find preventive solutions for ADR. For the ADR of TCM injection data collected during the search period from January 1, 2010 to December 31, 2020, the correlation between each section was analyzed by subdividing it into age, injection type, symptoms and causes. CNKI, PubMed, and EMBASE were used to collect the clinical data. 'Chinese herbal injection', 'Traditional Chinese Medicine injection', 'Chinese herbal injection side effect', 'Chinese herbal injection adverse drug reaction' were used for the keyword from the database. All data were collected mainly for TCM injection and the causes of ADR due to TCM injection. However, data not related to the relevant study or TCM injection were excluded from this study. Among a total of 941 studies collected during the search period from January 1, 2010 to December 31, 2020, a total of 10 studies were selected for final analysis. In 1462 clinical data sets, ADR by gender was higher in males than females. By age, 41 to 60 years were the most common. The incidence of ADR by injection type was highest in the blood regulating injection type. Data analysis showed Xueshuantong injection had the highest ADR. Among the symptoms of ADR, skin diseases were the most common. The most common cause of ADR was the unreasonable use of drugs. In China, for ADR management, the use of TCM injections is recommended according to the basic principles for the clinical use of TCM injections established by the Chinese government. In this study, we analyzed the current status and causes of ADR in TCM injections, and found a preventive solution. It is expected that it can be used as basic data to increase the usability of pharmacopuncture and herbal medicines in Korea in the future.

• Korean Journal of Pharmacognosy
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• v.44 no.2
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• pp.161-167
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• 2013

Aldose reductase (AR) has been shown to play an important role in the development of the diabetic complications. To discover novel treatments for diabetic complications from natural sources, 59 Chinese herbal medicines have been investigated for inhibitory activities on AR. Among them, 10 herbal medicines, Catalpa fargesii (stem and leaf), Saussurea Laniceps(whole plant), Alnus nepalensis(stem and leaf), Swertia macrosperma (whole plant), Woodfordia fruticosa (stem and leaf), Elsholtzia bodinieri (whole plant), Elsholtzia fruticosa (whole plant), Rosa multiflora (fruit), Nardostachys chinensis (whole plant), Eurya groffii (stem and leaf) exhibited a significant inhibitory activity compared with 3,3-tetramethyleneglutaric acid (TMG) as positive control. Particularly, 4 herbal medicines, C. fargesii (stem and leaf), S. Laniceps (whole plant), A. nepalensis (stem and leaf), S. macrosperma (whole plant) showed two times more potent inhibitory activity than TMG ($5.37{\mu}g/ml$).

• Journal of Veterinary Clinics
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• v.25 no.1
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• pp.27-30
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• 2008

A 5-year-old male Chihuahua with oral discomfort due to the presence of a maxillary acanthomatous epulis was referred to the acupuncture service at the Veterinary Medical Center of the University of Florida. For the patient, acupuncture treatments were performed for 11 sessions, at 1 month intervals with Chinese herbal medicine. The acupuncture points and Chinese herbal medicine used were selected based on TCM principles. The selected acupoints were Zusanli(ST36), Fenglong(ST40), Gongsun(SP4), Sanyinjiao(SP6), Pishu(BL20), Weishu(BL21), Taichang(LIV3), and Baihui(GV20). In addition, the Chinese herbal formulas Nei Xiao Wan and Si Jun Zi Tang were chosen. After one year of acupuncture and administration of Chinese herbal medicine, the acanthomatous epulis was remarkably decreased in size. It is considered that the use of acupuncture and Chinese herbal medicine would be useful treatments of canine acanthomatous epulis.

• Korean Journal of Plant Resources
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• v.7 no.2
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• pp.183-186
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• 1994

This study was conducted to investigate desirable storage method to major chinese herbal medicine materials, Moutan Radicis Cortex in different packing materials and sealing degree. The loss in weight of Moutan Radicis Cortex as influenced by packing materials was the lowest at complete sealing treatment with transparent or black polyethylene film. The rot ratio of Moutan Radicis Cortex during the storage period was not difference between packing materials, transparent and black polyethylene film, but rot ratio of complete sealing condition was lower than punch ($\phi$J5mm) on polyethylene film.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.3
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• pp.263-270
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• 2014

The objective of this study was to investigate the diagnosis and treatment of Raynaud disease such as syndrome differentiation and herbal medicine by reviewing Chinese traditional medicine's journals. The journal search was carried out using China National Knowledge Infrastructure(CNKI) and PubMed from January 2008 to August 2013. Searching key words were the various combination of "Raynaud disease", "traditional chinese medicine", "syndrome differentiation", "herbal medicine". The final selection of 38 studies were selected and summarized by researchers. The syndrome differentiation was classified as yang deficiency and cold syncope, qi stagnation and blood stasis. The most frequently prescribed herbal medication was Dangguisinitang.