• Parasites, Hosts and Diseases
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• 제37권4호
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• pp.265-270
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• 1999

The gene encoding Plasmodium vivax circumsporozoite protein (PvCSP) exhibits polymorphism in many geographical isolates. The present study was designed to investigate polymorphism in PvCSP gene of P. vivax isolates in Korea. Thirty isolates, obtained from indigenous cases in Yonchon-gun, Kyonggi-do in 1997, were subjected for sequencing and RFLP analysis of the repeat and post-repeat regions of PvCSP gene and two genotypes (SK-A and SK-B) were identified. The genotype of 19 isolates was SK-A and that of 11 isolates was SK-B. Although the number of 12-base repeats present in SK-A was three while two were found in a Chinese strain CH-5, the repeat sequence of SK-A was identical to that of CH-5 except for one base substitution. Compared with known data there was no identical isolates with SK-B, but the sequence of SK-B was similar to that of a North Korean (NK) isolate. These results indicate that two genotypes of PvCSP coexist in the present epidemic area of Korea and the present parasite may originate from East Asia. RFLP would be useful to classify genotypes of P. vivax population instead of gene sequencing.

• Journal of Community Nutrition
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• 제6권3호
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• pp.117-120
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• 2004

Objective : To get a better understanding of obesity and etiological factors of obesity among school children. Methods : We have conducted a questionnaire survey of 4542 (2395male and 2147female) age from 7-15 in Shanghai School District to study their 24h nutrition intakes ; we have asked all our survey participating students to take a physical exam and body mass index measurement to determine the morbidity of obesity. Common statistic method was used in analyzing the data. Results : The result shows an over all morbidity (boys and girls) of $12.3\%$ among the students we have studied. Our research shows that boys have a higher rate of morbidity of obesity $17.1\%$ vs. $7.0\%$ for girls. The morbidity for boys starts under age 10, reaches the peak at age 10 ($24.3\%$), then declines after age 11 ; as for girls the morbidity starts at under age 9, reaches the peak at 9, and then declines after 10. Our study also indicates that the daily nutrition intake of protein, fat and carbohydrate by the students have satisfied Chinese Dietary Reference Intakes (DRIs), while the daily intakes of calcium, iron, zinc, and vitamin C are below the $80\%$ of the DRIs suggested value. For students who are obese, our study shows that their average daily intakes of calories and protein have reached $90\%$ of the suggested value by the RNI while the intakes of calcium, iron, and zinc are far below standards. Furthermore, our research shows that the obese students usually intake more calories, proteins and vitamin $B_1$, but less for iron and calcium compared to the normal students. Some other factors such as the education and occupation of the parents, especially the mother, the family history of obesity and the eating habits are important factors that should be closely watched. Conclusion : The morbidity of obesity among boys is higher than girls. Obesity is closely related to the family history, the diet habits and the life styles.

• 대한한의학원전학회지
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• 제9권
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• pp.654-699
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• 1996

By studying Hwang Jae Nae Kyung(黃帝內經)'s O Haeng Kui Ryoo(五行歸類) in view of Chinese-Ancient-Thought like Chun In Hap Il Lon(天人合一論). Um Yang O Hang Lon(陰陽五行論). The theory of the month's age the conclusion is reached as follows 1. Chun In Hap Il Lon(天人合一論) means naturally men and nature consist of one energy to counteract each other and then developed to be concidered that the change of men and nature is same one;that is the basic thought of Hwang Jae Nae Kyung(黃帝內經) 2. Um Yang(陰陽) stands originally for the bright and the dark by sunrise or sunset. Ju Yuk Gye Sa Jun(周易繫辭傳) ahs considered Um Yang(陰陽) as the energy to explain changes of nature. O Haeng(五行) meaned originally five necessary materials or stuffs for living and then Chu Yun(鄒衍) has considered the difference between five powers in the nature through the combination with thought of O Haeng(五行). Hwang Jae Nae Kyung(黃帝內經) writes in the viewpoint of Um Yang O Haeng(陰陽五行) to analyze the changes of men and nature effectively. 3. O Haeng Kui Ryoo(五行歸類) is originated from Sang Su Hong Bum(尙書洪範) and its concrete examples are found in Kwan Ja(管子) and Yu SSi Chun Chu(呂氏春秋). O Haeng Kui Ryoo(五行歸類) in Hwang Jae Nae Kyung(黃帝內經) is widly affected by Kwan Ja O Haeng(管子五行) and adopts the opinion of Kum Mun Kyung Hak(今文經學) because of the background of times and medical physiology. 4. Hwang Jae Nae Kyung(黃帝內經) thinks that O Haeng(五行) means Mok(木) is the energy of being born, Hwa(火) growing-up, Kum(金) accumulating, Su(水) concluding, To(土) devoloping. O Haeng Kui Ryoo(五行歸類) in the heaven and the earth is classified by the property of O Haeng(五行). 5. O Haeng Kui Ryoo(五行歸類) in men can be explained so rationally with the property of O Haeng(五行) and the thery of an organism studied.

• 한방재활의학과학회지
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• 제29권4호
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• pp.61-72
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• 2019

Objectives We analyzed and organized present studies related to medical care for the disabled to establish an appropriate model of visiting health management for the people with disability. Methods To analyse study of medical care for the disabled, 11 electonic databases (PubMed, Chinese Academic Journals, EMBASE, Cochrane Library, Medline, Oasis, KMBASE, KISS, KISTI, NDSL, RISS) were searched from 2009 to 2018. There's no limit to the type of study. Results The search showed 20 domestic studies and 113 foreign studies that were screened for final inclusion of 37 studies. The all of domestic studies were relevant to dental research. The foreign studies have reported on the treatment of underlying diseases and medical services for the disabled. Conclusions Most studies have reported that government institutional support were needed for systematic treatment of the disabled. In the future, institutional support would be needed to establish the model of oriental doctor's visiting health management for the disabled.

• Journal of Veterinary Science
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• 제22권3호
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• pp.30.1-30.15
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• 2021

Background: New-generation adjuvants for foot-and-mouth disease virus (FMDV) vaccines can improve the efficacy of existing vaccines. Chinese medicinal herb polysaccharide possesses better promoting effects. Objectives: In this study, the aqueous extract from Artemisia rupestris L. (AEAR), an immunoregulatory crude polysaccharide, was utilized as the adjuvant of inactivated FMDV vaccine to explore their immune regulation roles. Methods: The mice in each group were subcutaneously injected with different vaccine formulations containing inactivated FMDV antigen adjuvanted with three doses (low, medium, and high) of AEAR or AEAR with ISA-206 adjuvant for 2 times respectively in 1 and 14 days. The variations of antibody level, lymphocyte count, and cytokine secretion in 14 to 42 days after first vaccination were monitored. Then cytotoxic T lymphocyte (CTL) response and antibody duration were measured after the second vaccination. Results: AEAR significantly induced FMDV-specific antibody titers and lymphocyte activation. AEAR at a medium dose stimulated Th1/Th2-type response through interleukin-4 and interferon-γ secreted by CD4⁺ T cells. Effective T lymphocyte counts were significantly elevated by AEAR. Importantly, the efficient CTL response was remarkably provoked by AEAR. Furthermore, AEAR at a low dose and ISA-206 adjuvant also synergistically promoted immune responses more significantly in immunized mice than those injected with only ISA-206 adjuvant and the stable antibody duration without body weight loss was 6 months. Conclusions: These findings suggested that AEAR had potential utility as a polysaccharide adjuvant for FMDV vaccines.

• 디지털융복합연구
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• 제20권5호
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• pp.129-138
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• 2022

COVID-19가 중국에서 전파된 이후에 중국의 의료 종사자들은 지속해서 감염될 위험과 강도 높은 업무로 인해 직무스트레스를 받고 있다. 이러한 문제는 심리적 웰빙이 감소시키는 주요 원인이다. 심리적 웰빙은 구성원의 행동에 영향을 미치고 직무성과가 영향을 줄 수 있다. 진정성 리더십은 구성원의 심리적 웰빙을 높일 수 있다. 그래서 본 연구는 구성원의 심리적 웰빙에 초점을 맞추고 진정성 리더십은 구성원들의 심리적 웰빙에 영향을 미치는 과정에서 상사와 의 갈등과 직무스트레스의 매개 역할을 규명하고 매개효과를 검증하였다. 이를 검증하기 위해 본 연구는 의료기관에 근무하는 314명의 구성원을 대상으로 실증연구를 하였다. 분석결과를 통해 진정성 리더십이 구성원의 심리적 웰빙을 높이는 과정에서 직무스트레스가 부정적 매개효과로 작용해 웰빙에 영향을 미친다. COVID-19 시대 맥락에서 본 연구는 의료진의 심리적 웰빙을 개선함으로써 그들의 심리적 웰빙의 수준을 향상하게 시키는 데 도움이 된다.

• 문화기술의 융합
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• 제7권4호
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• pp.577-582
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• 2021

본 연구는 코로나19 팬대믹 이후 외국인 환자의 급감으로 심각하게 타격을 입은 국내 의료관광 산업 회복을 위한 방안을 모색하고자 연구하게 되었다. 전문가 패널 에게 순위별 키워드 자문을 구하여 Kendall의 W검증을 사용하였다. 연구의 결론은 외국인 환자를 유치하는 기관은 중증 외국인 환자 치료 확대로 위기상황을 기회로 바꾸는 계기가 필요하겠다. 또한 가상, 증강현실을 통해 해외 방문이 어려운 상황에서 병원에 대한 친숙함과 신뢰를 얻을 수 있고 언택트 시대에 감염의 위험을 막고 환자를 보호 할 수 있는 원격지료 서비스를 시행함으로써 국내 입국을 하지 않고도 현지에서 의료의 혜택을 누릴 수 있다고 하겠다. 그리고 블록체인은 환자의 정보 보완을 유지하며 안전하게 공유가 가능하고 가상화폐 등을 활용한 지불 수단을 이용해 고객의 불편함을 최소화 할 수 있고 마지막으로 스마트 헬스 케어는 장소와 관계없이 환자를 관리하고 정보를 제공 할 수 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권15호
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• pp.6311-6316
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• 2015

Background: In mainland China, awareness of disease of elderly cancer patients largely relies on the patients' families. We developed a staged procedure to improve their awareness of disease. Materials and Methods: Participants were 224 elderly cancer patients from 9 leading hospitals across Southern China. A questionnaire was given to the oncologists in charge of each patient to evaluate the interaction between family and patients, patient awareness of their disease and participation in medical decision-making. After first cycles of treatment, increased information of disease was given to patients with cooperation of the family. Then patient awareness of their disease and participation in medical decision-making was documented. Results: Among the 224 cancer elderly patients, 26 (11.6%) made decisions by themselves and 125 (55.8%) delegated their rights of decision-making to their family. Subordinate family members tended to play a passive role in decision-making significantly. Patients participating more in medical decision-making tended to know more about their disease. However, in contrast to the awareness of disease, patient awareness of violation of medical recommendations was reversely associated with their participation in medical decision-making. Improvement in awareness of diagnosis, stages and prognosis was achieved in about 20% elderly cancer patients. About 5% participated more actively in medical decision-making. Conclusions: Chinese elderly cancer patient awareness of disease and participation in medical decision-making is limited and relies on their family status. The staged procedure we developed to improve patient awareness of disease proved effective.

• Parasites, Hosts and Diseases
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• 제56권5호
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• pp.437-446
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• 2018

To investigate the prevalence of Toxoplasma gondii in pork on the market in Korea, an in-house enzyme-linked immunosorbent assay for tissue fluid (CAU-tf-ELISA) was developed using a soluble extract of T. gondii RH strain tachyzoites. As the standard positive controls, the piglets were experimentally infected with T. gondii: Group A (1,000 cysts-containing bradyzoites), Group B (500 cysts-containing bradyzoites) and Group C ($1.0{\times}10^3$ or $1.0{\times}10^4$ tachyzoites). The CAU-tf-ELISA demonstrated infection intensity-dependent positivity toward tissue fluids with average cut-off value 0.15: 100% for Group A, 93.8% for Group B and 40.6% for Group C. When tissue-specific cut-off values 0.066-0.199 were applied, CAU-tf-ELISA showed 96.7% sensitivity, 100% specificity, 100% positive and 90.0% negative predictive values. When compared with the same tissue fluids, performance of CAU-tf-ELISA was better than that of a commercial ELISA kit. Of the 583 Korea domestic pork samples tested, anti-T. gondii antibodies were detected from 9.1% of whole samples and 37.9% from skirt meat highest among pork parts. In the 386 imported frozen pork samples, 1.8% (skirt meat and shoulder blade) were positive for anti-T. gondii antibodies. In Korea, prevalence of anti-T. gondii antibodies in the pork on retail markets appeared high, suggesting that regulations on pig farming and facilities are necessary to supply safe pork on the tables.

• 동의생리병리학회지
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• 제23권5호
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• pp.1055-1062
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• 2009

Magnolia obovata exhibit several beneficial effects including anti-oxidant effects. Magnolia obovata is used as a therapeutic agent to stop hemorrhages and a tonic to promoted health in Korean and Chinese medicine. The pharmacokinetic profiles of the main Magnolia obovata is still not accurately investigated. In present study, I examined the effects of water extracts of Magnolia obovata on atherosclerosis induced high cholesterol diet in rats in serum and abdominal aorta. A total of 3-week old 9 male rats of Sprague-Dawley were divided into 3 groups and fed with the basal diet (normal group), high cholesterol diet (atherosclerosis induced group) for 8 weeks, high cholesterol diet supplemented with water extracts of Magnolia obovata (Magnolia obovata group) for 2 weeks. And rats were sacrificed, serum lipid level, abodominal aortic anti-oxidant activities and lipid peroxide were measured. These results indicated that serum total cholesterol, LDL-cholesterol, triglycerides concentration significantly lower in Magnolia obovata group than high cholesterol diet group. But HDL-cholesterol concentration had significantly higher in Magnolia obovata group than high cholesterol diet group. In conclusion, Magnolia obovata controls of lipid level of hyperlipidemia and hypercholesterolemia, thus suppresses the proliferation of intima in endothelial cells, which is risk factors of atherosclerosis induced high cholesterol diet in rats. I consider as Magnolia obovata is worth to using as atherosclerosis treatment.