• 제목/요약/키워드: Children's Materials

검색결과 606건 처리시간 0.03초

Effects of Acute Lymphoblastic Leukemia on Ceruloplasmin Oxidase, Copper and Several Markers of Oxidative Damage, in Children

  • Mehdi, Wesen Adel;Yusof, Faridah;Mehde, Atheer Awad;Zainulabdeen, Jwan Abdulmohsin;Raus, Raha Ahmed;Abdulbari, Alaa Shawqi
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권13호
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    • pp.5205-5210
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    • 2015
  • Background: Acute leukaemia is characterized by fast growth of abnormal clones of haemopoietic precursor cells inside bone marrow leading to undue accumulation in the bone marrow. Acute lymphoblastic leukemia (ALL) is the most common form of childhood cancer. Materials and Methods: The study concerned 50 children diagnosed with ALL (mean age, $8.55{\pm}2.54$) compared to 40 healthy controls (mean age, $8.00{\pm}1.85$). The Hb, serum copper, ceruloplasmin oxidase, advanced oxidation protein products (AOPPs), total antioxidant activity (TAA) and protein were measured in all groups.One proteinous component was isolated by gel filtration chromatography from the precipitate produced by polyethylene glycol. Results: Significantly higher levels of AOPP, copper and decrease in total antioxidant activity were noted in the cases. Statistical analysis also showed a significant increase (p<0.01) in the activity of serum ceruloplasmin oxidase in patients with ALL compared to normal subjects .The maximum velocity (Vmax) and Michaelis constant had values of 104.2 U/L and 11.7 mM, respectively. The ${\Delta}H^*$ values for ceruloplasmin oxidase in ALL patients were positive, confirming the reaction to be endothermic. Conclusions: The results from this study showed a significant increase in AOPP, ceruloplasmine oxidase and decrease in total antioxidant activity .These parameters may play a role in development of DNA damage in childhood patients with acute lymphoblastic leukemia (ALL).The ${\Delta}S^*$ and ${\Delta}G^*$ values were negative, these refer that the reaction of ES formation is spontaneous, but needs energy in a so-called endergonic reaction. Also the negative ${\Delta}S^*$ value of ceruloplasmin oxidase indicates that the complex [$ES^*$] is further modulated through increasing structure arrangement.

한국의 패스트푸드 및 탄산음료에 관한 영양정책 방안제시 (A Suggestion to Develop a Nutrition Policy on Food and Nutrition Labeling and Education Systems for Fast Food and Carbonated Soft Drinks in Korea)

  • 정상진;김주현;이정숙;이다희;김숙희;유춘희
    • Journal of Nutrition and Health
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    • 제37권5호
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    • pp.394-405
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    • 2004
  • The objective of this study is to develop a nutrition policy on food and nutrition labeling and education systems for fast food and carbonated soft drinks in Korea by identifying the fast food and soft drink use and by examining nutrition policies and labeling in Korea and other countries. Fast food is defined as food dispensed quickly at a restaurant generally offering a limited menu of inexpensive items, which may be mostly not nutritious. It is a growing component of the Korean diet, especially on children and adolescent population. Low nutrient dense beverages such as carbonated drinks are also increasing in the children and adolescent's diet in Korea and concern has been raised that these beverages may replace more nutritious beverage and provide empty calories. According to 2001 Korean national health and nutrition survey, fast food and carbonated soft drinks were most popular among 13 - 19 years old adolescents. Thirty six and 72 percent of adolescents consumed hamburger and carbonated beverage equal to or more than once a week, respectively. In United States, all processed food including soft drinks should disclose full nutrition information by nutrition labeling requirement.. Restaurant foods are not required to provide nutrition information currently, but legislation on mandatory nutrition labeling of fast foods with other restaurant foods has been proposed currently in US. The sales of foods of minimal nutritional value, such as soft drinks, in the nation's schools is regulated by the United States Department of Agriculture. Nutrition information about fast food in US has been provided by fast food companies, non-profit organizations, hospitals and government through internet, booklet and brochure, etc, but the information is available from only a few resources in Korea. This study suggests a nutrition policy on fast food and soft drink use which includes establishing mandatory nutrition labeling and developing nutrition education materials and programs by web-site, booklet and government and school programs in Korea.

섬광판을 사용하는 조사문영상기구의 기본적인 선량반응성 (Basic Dose Response of Fluorescent Screen-based Portal Imaging Device)

  • 여인환
    • Radiation Oncology Journal
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    • 제17권3호
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    • pp.249-255
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    • 1999
  • 목적 : 본 연구의 목적은 섬광판을 사용하는 전자조사문영상장치의 기본적인 선량반응성을 연구하는 것이다. 대상 및 방법 : 팬텀의 두께와 구성 및 팬텀과 영상장치와의 거리를 변화시킴으로 영상장치에 입사하는 방사선질을 변화시켜가면서 조사면평면에서 신호를 읽었다. 또한 섬광에 의한 신호가 전체신호에 기여하는 상대적인 정도를 모사하였다. 결과 : 본 연구는 조사면평면상에서 선량분포가 팬텀과의 거리 및 팬텀의 두께의 함수임을 보였다. 팬텀의 구성에 따라 조사면영상장치에 의한 선량의 오차는 크게는 $7\%$ 에 달하는 것을 발견했다. 영상장치 내부에서 발생하는 섬광의 산란이 오차의 중요한 원인이 됨을 또한 발견했다. 결론 : 본 연구에서 우리는 조사면영상장치의 선량반응성의 기본적인 특성을 알았다. 또한 섬광판을 기초로 한 영상장치는 정확한 선량측정시스템이 되지 못함을 보았다.

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초등학교 영재 학생들의 과학자에 대한 인식 조사 (Gifted Children′s Perceptions of Scientists)

  • 임희준;여상인
    • 영재교육연구
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    • 제11권2호
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    • pp.39-57
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    • 2001
  • 본 연구에서는 영재교육기관에서 영재교육을 받고 있는 91명의 초등학교 3-5학년 학생을 대상으로 하여, DAST 와 과학자의 생활에 대한 지필 검사를 통하여 영재 학생들의 과학자에 대한 인식을 조사하였다. 연구 결과, 학생들은 전반적으로 과학자는 단정한 젊은 사람이라고 인식하였으며, 과학자의 성별은 주로 남학생은 남성으로, 여학생은 여성으로 인식하고 있었다. 또한, 과학자는 다른 사람들에게 보탬이 되고자 하고 새로운 것을 추구하는 의미 있는 활동을 하는 사람으로 인식하고 있었다. 즉, 영재 학생들의 전반적으로 과학자에 대하여 긍정적인 인식을 가지고 있었다. 그러나, 영재 학생들도 과학자의 연구는 대체로 실내에서 이루어지며, 주로 유리 기구나 시약을 가지고 실험을 하는 것으로 인식하고 있었으며, 실험에 수반되는 책이나 기타 자료, 그리고 컴퓨터와 같은 첨단 과학의 상징물들은 상대적으로 적게 나타났다. 또한 많은 영재 학생들이 과학자가 하는 일을 연구 또는 새로운 것을 발명하는 것이라고 생각하고 있으며, 과학자의 직업도 연구나 실험을 하는 사람이나 발명가로 인식하는 경우가 많았다. 그리고 과학자는 동료와의 협동적인 활동을 통해서 보다는 주로 혼자서 연구를 수행한다고 응답하였다. 이러한 과학자의 활동에 대한 학생들의 제한적이고 고정된 인식을 보다 개방적이고 유연하게 발전시키기 위하여 다양한 교육 방법들이 시도될 필요가 있다.

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One-stage Hip Reconstruction for Developmental Hip Dysplasia in Children over 8 Years of Age

  • Qadir, Irfan;Ahmad, Saeed;Zaman, Atiq uz;Khan, Chirag Muhammad;Ahmad, Shahzad;Aziz, Amer
    • Hip & pelvis
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    • 제30권4호
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    • pp.260-268
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    • 2018
  • Purpose: This study was performed to assess the clinical and radiological outcomes following one-stage hip reconstruction, consisting of open reduction femoral shortening and pelvic osteotomy, for neglected developmental dislocation of the hip (DDH). Materials and Methods: This is a retrospective analysis of 77 hips in 65 patients (46 females and 19 males; 12 had bilateral dislocations), operated at a Ghurki Trust Teaching Hospital in Pakistan between 2013 and 2015. The average age at surgery was $11.02{\pm}3.43$ years. According to the Tonnis classification, there were 10, 14, 22, and 31 patients in grades 1, 2, 3, and 4, respectively. The pelvic procedure utilized in this study was triple osteotomy (47 hips) followed by double and Salter osteotomy (18 and 12 hips, respectively). Postoperative evaluations were conducted using the modified MacKay's scoring system (functional outcomes) and Severin's scoring method (radiological assessment). Results: Postoperatively, there were 38 (49.4%), 19 (24.7%), 14 (18.2%), and 6 (7.8%) hips in Severin grade I, II, III and IV, respectively. According to the modified McKay criteria, there were 22 hips (28.6%) in excellent condition, 44 (57.1%) in good condition, 9 (11.7%) in fair condition and 2 (2.6%) in poor condition. Both patients with poor outcomes had an unstable, painful hip with evidence of avascular necrosis of the femoral head. Conclusion: Based on the results presented here, we recommend the single stage procedure of open reduction, femoral shortening and pelvic osteotomy for treatment of DDH in older children with good to excellent functional and radiological outcomes.

동물 분변으로 인한 모래 바닥재의 오염실태 및 관리 방안에 관한 연구 - 질소분석방법개발 - (A Study on Pollution Conditions and Management of Sand Flooring Related to Animal Feces - Nitrogen Analysis Method Development -)

  • 정원구;하영지;오근찬;허인량;최승봉
    • 한국환경보건학회지
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    • 제46권6호
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    • pp.646-654
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    • 2020
  • Objectives: Users of parks or children's play facilities have pointed to pets' bowel movements as the most serious problem when using them. In prior studies, a very low detection rate of parasites (eggs) in sand flooring materials has been found. Even though feces have been identified, no parasites (eggs) have been detected. Method: A standard solution of nitrate nitrogen was used to verify the reliability of a new nitrogen analysis method. The linearity, precision, and accuracy of the nitrate nitrogen analysis method were verified. Using this method, the pollution distribution of the sand flooring material and the degree of pollution at each point were investigated. Results: As a result of the verification of the nitrogen analysis method, the linearity was found to be good at r2=0.999 when distilled water is mixed in a standard substance solution. The standard substance additive solution r2=0.968 was found to be good. Precision represented 0.01 to 0.06% RSD for peak height. The recovery rate was 92.4 to 104.0 percent, indicating high accuracy. According to the same method of analysis, the flooring material sand at a general amusement facility with the largest number of concealed spaces was nitrate nitrogen 6.1 times higher than at the entrance of the playground. Also, in a comparison between clean sand and sandy flooring, the average nitrogen concentration of the sand flooring material was 24.4-167 times higher than pure sand. Conclusions: As such, no parasites (eggs) were detected at all points under investigation, but the sand flooring was exposed to animal fecal contamination. Therefore, the management of nitrogenous components should allow accurate identification of animal fecal contamination so that the timing of sand replacement can be managed hygienically and safely.

경기도 도시공원의 지정.조성 분석을 통한 개선방안 연구 (Recommendations for the Improved Urban Park Policy in Gyeonggi Province through Analyzing Designation and Creation Rationale)

  • 성현찬
    • 농촌계획
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    • 제13권3호
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    • pp.111-122
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    • 2007
  • This study aims at providing basic policy materials to build a basis for supplying and creating urban parks balanced across Gyeonggi province and improving the quality of life of residents through, an extensive analysis of all city parks in cities/counties in Gyeonggi province. The study result showed that first, the number of parks is only 40% of the adequate number and, thus, accessibility of Gyeonggi province residents to parks in neighborhoods is significantly low. Second, a proportion of park types in children's park, neighborhood park, urban nature park is 67% : 24% : 2%, which is adequate in Gyeonggi province as a whole. Third, as for the area of parks per resident, the area of designated park is $17.7m^2$/person, which is over three times of legal requirement in urban planning area ($6m^2$/person). However, created park area is only $5.6m^2$/person, which fails to meet the legal requirement. Fourth, when park area of each city was compared, the areas varied significantly across cities. The Gyeonggi provincial government needs to secure funds aggressively and accelerate setting up and expanding facilities at designated parks located within the current urban areas. The findings from this study should be used as important materials when developing supply & demand policies for urban parks in Gyeonggi province. The study implicates that independent park policies and management by each city/county as well as the establishment and management of a comprehensive park policy at a provincial level is significantly important.

가족치아를 이용한 골이식술: 증례보고 (Familial Tooth Bone Graft: Case Reports)

  • 이지영;김영균;엄인웅;최준호
    • 대한치과의사협회지
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    • 제51권8호
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    • pp.459-467
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    • 2013
  • The use of autogenous tooth bone graft material has been commercialized since 2008. Autogenous tooth bone grafts always require that the tooth of the patient be extracted, and thus, the use of graft material are limited in many cases. For solution of limitation in quantity and concurrent use of autogenous tooth bone graft material, the grafting of familial teeth has been suggested. It has the following advantages: the teeth of family members are used as bone graft materials, the genetic composition is identical, and potential genetic and infectious risks can be minimized. Because the teeth of family members are used, a good tissue affinity is obtained, and thus, superior bone generation rates compared to those observed for allogenic or xenogenic bones can be anticipated. We used familial tooth bone-graft materials for alveolar ridge augmentation, socket preservation, and maxillary sinus graft in some cases. In most cases, the impacted third molars of their children were prepared as bone graft material and were used for surgery. In one case, the impacted third molar from the patient's brother was used as bone graft material. We obtained satisfactory result and these cases are reported herein.

아파트 단위주거의 리모델링 요소와 현황 - 인테리어디자인업체 실무자와 거주자 심층면접을 통하여 - (Elements and Actual Condition of Apartment Unit Remodeling - By In-depth Interviews on Residents and Specialists of Interior Design Companies -)

  • 최윤정;심현숙;정연홍
    • 한국주거학회논문집
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    • 제18권6호
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    • pp.57-67
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    • 2007
  • The purpose of this study was to grasp major elements and actual condition of apartment unit remodeling by in-depth interviews on residents and specialists. The interviews had been conducted to interior designers who have a wide experience of apartment remodeling and residents who live in recently remodeled apartment unit. In-depth interview is a kind of qualitative method in which attention to reply of responses with open-access between interviewer and respondents. According to the results, remodeling elements were generally changing of lighting fixtures and finishing materials in the all spaces, integration of balcony into children's room, installation of furniture in kitchen and entrance, changing storage furnitures and equipments in bathroom. Artificial lighting method were selected generally whole lighting. Finishing materials were used ordinary (non environmentally-friendly) wallpaper and adhesion and tempered floor. There were unsatisfied factors after remodeling, these were dissatisfaction of design, construction defects, and stink of reflecting 'sick house'. Also they responded that they should be considering to use environmentally-friendly material at next remodeling.

유치원 교육과정 기반 영양·식생활 교육 내용 체계화: 질적 기초 연구 (Systematization of food and nutrition education content based on national kindergarten curriculum: a qualitative formative study)

  • 김정현;심유진;백은영
    • 대한지역사회영양학회지
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    • 제28권6호
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    • pp.509-522
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    • 2023
  • Objectives: This study is intended to develop a curriculum for kindergarten food and nutrition education aimed at preschool children, reflecting government policy and meeting the demands of preschool settings. Methods: Existing educational materials were analyzed, and key elements of the 2019 Revised Nuri Curriculum ("Nuri Curriculum") and Guidelines for Nutrition and Food Education in Kindergartens, Elementary, Middle, and High Schools ("Guidelines") were examined as foundational information for developing the curriculum for food and nutrition education. Results: Basing ourselves on the five domains of the Nuri Curriculum, "Physical Activity and Health," "Communication," "Social Relationships," "Art Experience," and "Natural Science Inquiry," we integrated three areas from the Guidelines, namely "Dietary Habits and Health," "Dietary Habits and Safety," and "Dietary Habits and Culture," to structure the curriculum for kindergarten food and nutrition education. Three specific domains, "Nutrition and Health," "Food and Culture," and "Safe Dietary Practices," were tailored for preschool children, each comprising core concepts, content elements, and educational materials. In the "Nutrition and Health" domain, core concepts such as "nutrition" were addressed through content elements such as "balanced eating" and "vegetables and fruit," while "health" included elements such as "eating regularly" and "nutrients for disease prevention," each with two educational content components. The "Food and Culture" domain focused on "food" with content on "local foods (vegetable-garden experience)" and "food culture" with content on "our dining table (rice and side dishes)," "our agricultural products," "global cuisine (multiculture)," and "considerate dietary practices," each with four educational content components. The "Safe Dietary Practices" domain included core concepts such as "hygiene" with content on "hand-washing habits" and "food poisoning management," and "safety" with content on "food labeling." Conclusions: The systematized curriculum for kindergarten food and nutrition education aligns with the Nuri Curriculum and is interconnected with the Guidelines. This curriculum can be used as foundational material for developing educational resources tailored to the characteristics of preschoolers, contributing to effective implementation in early childhood education.