• 제목/요약/키워드: Childhood ALL

검색결과 721건 처리시간 0.033초

소아 일차성 신증후군의 치료반응과 재발빈도에 관련된 인자 (Predictive Clinical Factors for the Treatment Response and Relapse Rate in Childhood Idiopathic Nephrotic Syndrome)

  • 전학수;안병훈;하태선
    • Childhood Kidney Diseases
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    • 제10권2호
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    • pp.132-141
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    • 2006
  • Purpose : This study was aimed to determine the predictive risk factors for the treatment response and relapse rate in children diagnosed with idiopathic nephrotic syndrome. Methods : We analyzed the medical records of children who were diagnosed and treated for childhood idiopathic nephrotic syndrome from November 1991 to May 2005. Variables selected in this study were age at onset, sex, laboratory data, concomitant bacterial infections, days to remission, and interval to first relapse. Results : There were 46 males and 11 females, giving a male:female ratio of 4.2:1. The age($mean{\pm}SD$) of patients was $5.8{\pm}4.1$ years old. Of all patients who were initially given corticosteroids, complete remission(CR) was observed in 54(94.7%). Of the 54 patients who showed CR with initial treatment, 40(70.2%) showed CR within 2 weeks and 14(24.6%) showed CR after 2 weeks. The levels of serum IgG were lower in the latter group who showed CR after 2 weeks(P=0.036). Of the 54 patients who showed CR with initial treatment, 47(82.5%) relapsed. Of these patients, 35.1% were frequent relapsers and 43.9% were infrequent relapsers. There was no significant correlation between the frequency of relapse and the following variables : sex, days to remission, and laboratory data. However, age at onset and interval to first relapse had a negative correlation with the frequency of relapse(Pearson's coefficient=-0.337, -0.433, P<0.012, P<0.01). Conclusion : The age at onset and the interval to first relapse were found to be predictive clinical parameters for the relapse rate, while the levels of serum IgG at initial presentation were a predictive laboratory factor for treatment response in childhood idiopathic nephrotic syndrome.

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Evaluation of the Histo-Epidemiological Profile of Solid Childhood Cancers in Togo

  • Darre, Tchin;Maneh, Nidain;Kpatcha, Matchonna;Boume, Azanledji;Padaro, Essohana;Amegbor, Koffi;Napo-Koura, Gado
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권1호
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    • pp.81-83
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    • 2016
  • Background: Cancer is a subject of continuing concern, more common in adults than in children, but often with a poor outcome in the latter. Our study set itself the objective to describe the epidemiological and histological aspects of solid cancers in children in Togo. Materials and Methods: This descriptive, cross-sectional study focused on cases of solid cancers in children diagnosed from 2010 to 2014 (5 years) at the pathology laboratory of the Tokoin teaching hospital. Data were collected from the records of that laboratory. Results: We collected 66 cases of childhood cancer representing 5% of all solid cancers. The annual incidence was 13.2 cases. The sex ratio (M/F) was 1.4; mean age was of $7.2{\pm}1.6years$. The age group most affected was that of 5-9 years (40.9%). Four histological groups of solid childhood cancers were listed: lymphoma (n=34 cases; 51.5%), embryonic cancer (n=17 cases; 25.8%), sarcomas (n=13 cases; 19.7%) and carcinoma (n=2 cases; 3%). The most common histological types were Burkitt lymphoma (36.4%), nephroblastoma (10.6%) and retinoblastoma (10.6%). Conclusions: This study shows that solid cancers in children are relatively frequent in Togo with a male predominance. They are still largely dominated by Burkitt lymphoma, followed by retinoblastoma and nephroblastoma.

유치원 교육에 관한 학부모의 인식과 기대에 관한 실태조사 (A study on the perception and expectation of Parent about Kindergarten Education)

  • 신귀순
    • 한국생활과학회지
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    • 제14권6호
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    • pp.899-913
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    • 2005
  • The purpose of the study is to analyze the perception and expectation made by parents, regarding the goal, methods and management of kindergarten education. The study is designed to identify social needs for the early childhood education and to produce some important information necessary for the development of education programs for kindergarteners and for the management of a kindergarten. As subjects of the study, 623 mothers of kindergartens were sampled from kindergartens. The researcher constructed a questionnaire of multiple-choice type for surveying opinions of the subjects, based on the analysis of curriculum materials published by Korean Ministry of Education. In data analysis, frequency of response on each item of the questionnaire was tabulated, and chi-square test was applied for testing the difference between independent samples. The results of the study are summarized as followings: First, parents feel kindergarten education necessary because 'interaction with peers' itself must be an important condition for socialization of younger children. For an 'ideal personality' to be pursued in kindergarten education, parents place 'moral personality' in the first priority.' And for educational objective of kindergarten they select 'development of cooperative attitude' as the most important one. Second, 'play method' is emphasized by parents as the most desirable educational method for kindergartener. Third, they think it is necessary for parents to participate in the management of kindergarten. And they also feel that parents of kindergartener should be educated on the early childhood education. Fourth, parents emphasize that the early childhood education should be integrated into a public educational system in order to provide equal educational opportunity for all preschoolers.

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유아리더십이 사회적 유능감에 미치는 영향 (Effects of Children's Leadership Skills on Social Competency)

  • 신수원;임난주
    • 한국산학기술학회논문지
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    • 제15권3호
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    • pp.1465-1470
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    • 2014
  • 본 연구는 유아의 사회적 유능감을 위하여 유아의 리더십이 사회적 유능감에 미치는 영향을 조사하였다. 서울, 인천, 경기 지역의 만5세 남녀유아 330명을 설문조사하여 자료처리를 t-검증, f-검증을 적용하여 person상관분석을 실시하였다. 연구결과는 첫째, 유아의 성별에 따라 의미 있는 차이를 보였고 남아보다 여아가 리더십, 사회적 유능감 점수가 더 높은 것으로 나타났다. 둘째, 유아리더십과 사회적 유능감 간의 상관관계를 분석한 결과는 통계적으로 유의미한 차이를 보이는 것으로 나타났다. 셋째, 리더십 수준이 높은 집단일수록 사회적 유능감이 높은 것으로 나타났다. 결론적으로 본 연구에서는 유아의 리더십이 유아의 사회적 유능감에 미치는 영향이 크다는 것이 입증 되었다. 따라서 본 연구에서 나타나는 결과는 유아의 리더십을 향상시키는 유아 리더십 교육프로그램을 통하여 유아의 사회적 유능감을 증진 시킬 수 있다는 교육적 시사점을 가질 수 있다.

경제적 수준과 교수효능감의 관계에서 자아존중감의 매개효과: 예비유아교사를 중심으로 (The Mediating Effects of Self-esteem on the Relationship between Economic Level and Teaching Efficacy : Focused on Early Childhood Preservice Teacher)

  • 하정희;이종만
    • 디지털융복합연구
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    • 제15권2호
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    • pp.393-403
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    • 2017
  • 본 연구에서는 예비유아교사의 경제적 수준과 자아존중감 및 교수효능감의 상관관계를 살펴보고, 경제적 수준과 교수효능감의 관계에서 자아존중감의 매개효과에 대해 알아보고자 하였다. 연구대상은 인천시에 소재한 2개 대학의 유아교육과 학생 457명이며 수집된 자료는 SPSS 통계 프로그램을 사용하여 적률상관분석과 중다회귀분석을 실시하였다. 연구결과 주요변수들 간에 모두 정적상관이 있었으며 경제적 수준과 개인적 교수효능감의 관계에서 자아존중감의 매개효과가 나타났다. 연구결과, 주요변수들 간에 모두 정적상관이 있었으며 경제적 수준과 개인적 교수효능감의 관계에서 자아존중감의 매개효과가 나타났다. 경제적 수준과 일반적 교수효능감의 관계에서는 자아존중감의 매개효과가 나타나지 않았다. 본 연구를 통해 예비유아교사의 자아존중감과 교수효능감에 대한 경제적 수준의 영향력을 파악하고 이를 고려하여 예비유아교사의 교수효능감 신장을 위한 교육과정의 개발과 지도가 필요함을 시사하고 있다.

아동기 비만이 혈장 지질, 혈압 및 혈당에 미치는 영향 (Relationships of Obesity in Childhood to Plasma Lipids, Blood Pressure and Blood Glucose)

  • 임현숙;이종임
    • 한국식품영양과학회지
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    • 제22권6호
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    • pp.724-733
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    • 1993
  • In order to investigate the relationships of obesity in childhood to plasma lipid, blood pressure and blood glucose concentration, we selected 21 subjects for the moderate obese group(MO), 9 for mild obese group(MI), and 19 for the control group(C) among children aged 10~12. While the level of plasma triglyceride and VLDL-cholesterol of the MO group was much higher than that of group C, a significantly lower percentage of HDL-cholesterol was found in the MO compared to the percentage found in group C. Also the level of the total cholesterol and LDL-cholesterol of the MI group as well as the MO was much higher than that of C. The elevated total-cholesterol level of the Mi group was due to increased LDL-cholesterol and that of the MO was due to increases in both VLDL-cholesterol and LDL-cholesterol. As the result of these differences, the atherogenic index of the MO was significantly higher than that of C. The incidence of hypercholesterolemia( 200mg/dl) of the MI and MO was 60.0% and 77.8% respectively, All of the physical parameters and indexes except height were positively correlated with plasma lipid levels, systolic blood pressure, and blood glucose concentration. The analyses of the correlated with plasma lipid levels, systolic blood pressure, and blood glucose concentration. The analyses of the correlation indicated that central fat to peripheral fat ratio and waist to thigh girth ratio seemed to be closely associated to plasma lipid levels and atherogenic index. The MO had significantly higher systolic blood pressure than C and significantly higher blood glucose concentration was found in both MI and MO than in C. These results confirmed that obesity in childhood may be relevant to chronic metabolic diseases such as abnormal lipid metabolism, atherosclerosis, high blood pressure and diabetes mellitus.

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유아인지발달을 위한 코딩게임의 개발과 적용 효과 (The Development and Application Effect of Coding Game for the Childhood Cognitive Development)

  • 홍대선;유미;이형구
    • 한국게임학회 논문지
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    • 제18권5호
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    • pp.103-112
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    • 2018
  • 게임을 통해 순차, 반복문, 조건문 개념 학습이 가능하도록 개발된 유아교육용 코딩게임 "Ito2"를 소개하였다. 개발된 게임은 실제 어린이집 아동을 대상으로 모의수업과 실습수업의 두 단계의 과정을 거쳐서 코딩교육을 실시하여 그 실효성을 검증하였다. 코딩 교육을 실시함에 따라 공간, 관찰, 도형 및 측정, 분류, 비교 및 서열화, 부분과 전체의 총 6개 분야에 대한 유아 인지발달 능력 성취도의 추이를 관찰하여 그 변화 정도를 기술하였다. 본 논문은 재미 요소에 학습 요소를 더한 유아 기능성 코딩게임을 개발하고 개발된 게임을 어린이집 아이들이 학습게임으로 체험하면서 인지발달과 공간지각능력에 있어서 능력 향상이 이루어짐을 확인하였다.

The Prevalence of Atopic Dermatitis, Asthma, and Allergic Rhinitis and the Comorbidity of Allergic Diseases in Children

  • Hong, So-Young;Son, Dong-Koog;Lim, Wan-Ryung;Kim, Sun-Hang;Kim, Hyun-Jung;Yum, Hye-Yung;Kwon, Ho-Jang
    • Environmental Analysis Health and Toxicology
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    • 제27권
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    • pp.6.1-6.8
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    • 2012
  • Objectives: Childhood allergic diseases are a major concern because they lead to a heavy economic burden and poor quality of life. The purpose of this study was to investigate the prevalence of childhood atopic dermatitis, asthma, allergic rhinitis, and the comorbidity of allergic diseases in Seoul, Korea. Methods: We conducted a cross-sectional survey between May and October 2010 to evaluate the prevalence of childhood allergic diseases, including atopic dermatitis, asthma, and allergic rhinitis, using a questionnaire from the International Study of Asthma and Allergies in Childhood group. Each questionnaire was completed by the parent or guardian of a child. Results: In the 31,201 children studied, the prevalence of atopic dermatitis symptoms in the past 12 months was 19.3% in children 0 to 3 years of age, 19.7% in children 4 to 6 years of age, 16.7% in children 7 to 9 years of age, and 14.5% in children 10 to 13 years of age (p for trend < 0.001). The prevalence of asthma in these age groups was 16.5%, 9.8%, 6.5%, and 5.4%, respectively (p for trend < 0.001). The prevalence of allergic rhinitis in these age groups was 28.5%, 38.0%, 38.5%, and 35.9%, respectively (p for trend = 0.043). The percentage of subjects with both atopic dermatitis and asthma, both asthma and allergic rhinitis, or both atopic dermatitis and allergic rhinitis was 2.5%, 4.7%, and 8.7%, respectively. The prevalence of comorbid allergic diseases decreased with age (p for trend < 0.001). Conclusions: Our study revealed that the prevalence of some allergic diseases, such as atopic dermatitis and asthma, was relatively high in very young children and that all of the principal allergic diseases in children often co-exist.

Comparative evaluation of obesity-related parameters in junior sumo wrestlers and children with obesity

  • Ogawa, Miori;Sagayama, Hiroyuki;Tamai, Shinsuke;Momma, Reiko;Hoshi, Daisuke;Uchizawa, Akiko;Ichikawa, Go;Arisaka, Osamu;Watanabe, Koichi
    • 운동영양학회지
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    • 제25권3호
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    • pp.36-43
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    • 2021
  • [Purpose] Exercise is a key factor in preventing obesity and metabolic syndrome. Sumo wrestlers increase their body size from childhood for athletic advantage; however, the risk of metabolic syndrome in junior sumo wrestlers is undetermined. Preventive measures against pediatric obesity should be initiated during childhood to prevent obesity in adulthood, considering its high global incidence. We comparatively evaluated the risk factors for metabolic syndrome in junior sumo wrestlers and children with obesity. [Methods] We enrolled 70 male children (age 9-17 years [sumo group, n = 14] and 9-14 years [other sports and non-exercise groups, n = 28 each]) and evaluated their anthropometric parameters (height, weight, body mass index z-score, obesity rate, waist circumference, waist to height ratio) and hematological parameters (total, low-density, high-density, and non-high-density lipoprotein-cholesterol; triglycerides; plasma glucose, and glycated hemoglobin levels). [Results] The BMI z-score, obesity rate, waist circumference (p < 0.05, along with the non-exercise group), and systolic blood pressure were significantly higher and the high-density cholesterol level was lower in the sumo group than in the other sports group (p < 0.05). The waist to height ratio was significantly higher in the non-exercise group than in the other sports group (p < 0.05). No significant difference was found in other blood lipid, plasma glucose (significantly lower level than the reference range in the sumo group, p < 0.05), and glycated hemoglobin (within the reference range in all groups) levels among the three groups. [Conclusion] Junior sumo wrestlers had a larger body size and higher blood pressure than children with obesity who exercised regularly. This provides direction for future research into targeted preventive interventions against metabolic syndrome for junior sumo wrestlers with large body size.

소아 단순 비만의 변증 유형, 변증별 증상, 치법 및 한의치료 분석 - 중의학 논문을 중심으로 - (Analysis of Pattern Identification and Related Symptoms, Treatment Principles and Korean Medicine Treatments on Childhood Simple Obesity -Focused on Traditional Chinese Medicine Literature-)

  • 정윤경;김재현;방미란;이보람;장규태
    • 대한한방소아과학회지
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    • 제37권1호
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    • pp.15-44
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    • 2023
  • Objectives The purpose of this study is to analyze the types of childhood simple obesity and suggest clinical symptoms, treatment principles, and traditional Chinese medicine (TCM) treatments for each type. Methods All kinds of literature published by the China National Knowledge Infrastructure (CNKI) up to August 20, 2022 were analyzed. We extracted information about types of childhood simple obesity, relevant clinical symptoms, treatment principles and TCM treatments. Results 25 studies were included. Spleen deficiency with dampness obstruction, gastrointestinal dampness-heat, internal excess of phlegm-dampness were the most reported. Spleen deficiency with dampness obstruction has symptoms of powerless, heavy limbs, pale tongue, teeth-marked tongue, sunken and slippery pulse. As a treatment, herbal medicine (HM) like modified Banggihwanggitang and acupoint like Joksamri were mainly reported. Gastrointestinal dampness-heat has symptoms of thirst, constipation, edacity, rapid hungering, heavy limbs, red tongue, slippery and rapid pulse. HM like Modified Xiehuangsan to clear heat was mainly reported. Internal excess of phlegm-dampness has symptoms of heavy limbs, lack of strength, tongue with white slimy fur, slippery pulse. Modified Ijintang to dry dampness to resolve phlegm was mainly reported. Conclusions This study analyzed types of pattern, clinical symptoms, treatment principles, and TCM treatments of childhood simple obesity. Based on this study, it is necessary to derive a standardized dialectical information that reflects the domestic situation.