• Tuberculosis and Respiratory Diseases
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• 제69권3호
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• pp.177-183
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• 2010

Background: Smoking reduces pulmonary function and induces various lung diseases. Recently, the rate of emphysema detection has increased due to lung cancer screening with low-dose chest computed tomography (CT). The purpose of this study was to evaluate changes in lung function associated with emphysema in healthy smokers. Methods: One hundred and ninety one healthy smokers, who had undergone a low-dose chest CT (LDCT) scan as part of lung cancer screening and had revisited the health center after a median 23.9 months' time, were recruited into this study. The severity of emphysema was calculated by the direct observation of a radiologist and a pulmonologist indipendently. Longitudinal changes in lung function according to emphysema based on LDCT and type of smoker was analyzed. Results: Of the participants in this study, 25% of healthy smokers had emphysema, which was mild in severity, in older patients (p=0.003) and in heavy smokers (p<0.001). $FEV_1/FVC$ and FEF25-75% were decreased in current smokers with emphysema (p=0.001 and p=0.009, respectively) and without emphysema (p=0.001 and p=0.042). Although lung function was not decreased in ex-smokers without emphysema, $FEV_1/FVC$ and FEF25-75% were decreased in ex-smoker with emphysema (p=0.020 and p=0.010). Conclusion: Upon examination with LDCT, the prevalence of emphysema was higher in healthy smokers was than in non-smokers. Lung function was diminished in smokers with emphysema, in spite of former smoker.

• Tuberculosis and Respiratory Diseases
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• 제56권2호
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• pp.216-220
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• 2004

폐전이에서 공동성 폐병변이 관찰되는 경우가 흔하지 않으며, 다른 양성 폐병변과 감별이 필요하다. 저자들은 다발성 공동성 폐병변을 주소로 내원한 환자에서 굴곡성 기관지내시경 검사를 통한 조직검사상 전이성 폐암을 진단하였고 원발성 병변인 담관암을 진단하여 전신적인 항암약물을 시행한 경험이 있어 이에 보고하는 바이다.

• Journal of Chest Surgery
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• 제51권6호
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• pp.376-383
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• 2018

Background: The aim of this study was to evaluate the outcomes of surgical resection in patients with radiographically noninvasive lung adenocarcinoma according to the surgical strategy. Methods: A retrospective study was conducted of 128 patients who underwent pulmonary resection for ground-glass opacity (GGO)-dominant nodules measuring ${\leq}2cm$ with a consolidation/tumor ratio ${\leq}0.25$ based on computed tomography between 2008 and 2015. The 5-year disease-free survival (DFS) rate and 5-year overall survival (OS) rate were analyzed. Results: Among the 128 patients, wedge resection, segmentectomy, and lobectomy were performed in 40 (31.2%), 22 (17.2%), and 66 patients (51.6%), respectively. No significant differences were found among the groups in the mean size of tumors (p=0.119), the rate of pure-GGO nodules (p=0.814), the consolidation/tumor ratio (p=0.695), or the rate of invasive adenocarcinoma (p=0.378). Centrally located tumors were more common in the lobectomy group (21.2%) than in the wedge resection (0%) or segmentectomy (0%) groups (p=0.001). There were no significant differences in the 5-year DFS rate (100%, 100%, 92.7%, respectively; p=0.76) or 5-year OS rate (100%, 100%, 100%; p=0.223) among the wedge resection, segmentectomy, and lobectomy groups. Conclusion: For radiographically noninvasive lung adenocarcinoma measuring ${\leq}2cm$ with a consolidation/tumor ratio ${\leq}0.25$, wedge resection and segmentectomy could be comparable surgical options to lobectomy.

• Korean Journal of Radiology
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• 제21권9호
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• pp.1055-1064
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• 2020

Objective: To assess the incremental prognostic value of coronary computed tomography angiography (CCTA) in comparison to a clinical risk model (Framingham risk score, FRS) and coronary artery calcium score (CACS) for future cardiac events in ischemic stroke patients without chest pain. Materials and Methods: This retrospective study included 1418 patients with acute stroke who had no previous cardiac disease and underwent CCTA, including CACS. Stenosis degree and plaque types (high-risk, non-calcified, mixed, or calcified plaques) were assessed as CCTA variables. High-risk plaque was defined when at least two of the following characteristics were observed: low-density plaque, positive remodeling, spotty calcification, or napkin-ring sign. We compared the incremental prognostic value of CCTA for major adverse cardiovascular events (MACE) over CACS and FRS. Results: The prevalence of any plaque and obstructive coronary artery disease (CAD) (stenosis ≥ 50%) were 70.7% and 30.2%, respectively. During the median follow-up period of 48 months, 108 patients (7.6%) experienced MACE. Increasing FRS, CACS, and stenosis degree were positively associated with MACE (all p < 0.05). Patients with high-risk plaque type showed the highest incidence of MACE, followed by non-calcified, mixed, and calcified plaque, respectively (log-rank p < 0.001). Among the prediction models for MACE, adding stenosis degree to FRS showed better discrimination and risk reclassification compared to FRS or the FRS + CACS model (all p < 0.05). Furthermore, incorporating plaque type in the prediction model significantly improved reclassification (integrated discrimination improvement, 0.08; p = 0.023) and showed the highest discrimination index (C-statistics, 0.85). However, the addition of CACS on CCTA with FRS did not add to the prediction ability for MACE (p > 0.05). Conclusion: Assessment of stenosis degree and plaque type using CCTA provided additional prognostic value over CACS and FRS to risk stratify stroke patients without prior history of CAD better.

• 척추신경추나의학회지
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• 제10권2호
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• pp.27-35
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• 2015

Objectives: The purpose of this study is to discriminate the cough-induced rib fracture with chest pain occurred after chuna therapy. Methods: A 68-year-old female patient who is suffering from left chest wall pain with chronic cough was treated by Korean medical treatment and chuna therapy from November 11th 2014 to November 15th 2014. The improvement of the patient's pain was measured by 100 mm Visual Analog Scale (VAS). For diagnosis the rib fracture, we conducted the radiography, computed tomography (CT), and bone scan. Results: After treatment, pain intensity was decreased and the rib fracture was negative in radiography and CT. But, in bone scan, the 5th-8th rib fractures in left side were detected. Conclusions: When the patient with chest pain visit the hospital after chuna therapy, a doctor keep in mind the possibility of coughinduced rib fracture.

• Clinical and Experimental Pediatrics
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• 제51권10호
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• pp.1123-1126
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• 2008

폐조직과 흉막의 흉곽의 결손 부위를 통한 돌출로 정의되는 폐탈장은 선천성 또는 후천적일수도 있으며 부위별로 경부, 흉부, 횡경막 탈장이 있다. 8개월된 남아가 4개월간의 지속적인 기침과 흉부 방사선 촬영에서 폐우하엽의 지속적인 음영 증가소견 있어 시행한 흉부 전산화 단층촬영에서 azygoesophageal recess를 통한 폐탈장이 관찰되었다. 아직까지 보고된 적이 없는 azygoesophageal recess를 통한 폐탈장이 저자들에 관찰하게 되어 보고하는 바이다.

• Journal of Chest Surgery
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• 제47권5호
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• pp.483-486
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• 2014

A 76-year-old male underwent a left upper lobectomy with wedge resection of the superior segment of the left lower lobe using video-assisted thoracoscopic surgery (VATS) for non-small-cell lung cancer of the left upper lobe. He presented with shortness of breath, fever, and leukocytosis. Chest radiography showed atelectasis at the remaining left lower lobe. Bronchoscopy revealed narrowing of the left lower bronchus with purulent secretion, and computed tomography showed downward kinking of the left lower lobar bronchus. He underwent exploratory VATS, and intraoperative findings showed an inferiorly kinked left lower lobar bronchus with upward displacement of the left lower lobe. After adhesiolysis, the kinked bronchus was straightened, and bronchopexy was performed to the pericardium to prevent the recurrence of bronchial kinking. Also, the inferior pulmonary ligament was reattached to prevent upward displacement. Postoperative follow-up bronchoscopy revealed no evidence of residual bronchial obstruction, and chest radiography showed no atelectasis thereafter.

• Tuberculosis and Respiratory Diseases
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• 제70권6호
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• pp.511-515
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• 2011

The fat-forming variant of solitary fibrous tumors (SFTs) is a rare soft tissue neoplasm that was previously referred to as a lipomatous hemangiopericytoma (L-HPC). The most common affected site is deep soft tissue. Here, we present the first case, worldwide, of a fat-forming variant of SFT of the pleura. A 74-year-old man presented with left lower chest pain. Chest radiographs showed a mass-like lesion at the left lower lung field and chest computed tomography revealed a 12 cm fat-containing enhancing mass that was well-separated, lobulated and inhomogeneous. Radiology findings suggested a liposarcoma. Percutaneous needle biopsy was performed and pathological diagnosis of the mass was a fat-forming variant of SFT. Surgical resection was carried out and there has been no recurrence to date. So, a benign fat-forming variant of SFT must be considered as one of the differential diagnoses of lipomatous tumors of the pleura.

• 대한암한의학회지
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• 제19권1호
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• pp.61-68
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• 2014

Objectives : To study the effect of SB injection on tumor size in an advanced non-small cell lung cancer patient. Methods : A patient was clinically diagnosed as advanced non-small cell lung cancer (Stage IIIa). Four cycles of intravenous SB injection were conducted. Each cycle lasted 4 days. The content of 7vials SB was injected every day. To compare the tumor size before treatment and after four cycles of SB injection, chest computed tomography (CT) was performed. Results : Follow-up CT images showed that the tumor size was reduced. In admission, size of the tumor $6.7{\times}8.5{\times}9.5cm$ on the left lower lobe of lung. After SB injection, size of the tumor $5.6{\times}6.8{\times}8.4cm$ by Chest CT. The patient's symptoms such as cough, sputum were improving until four cycles of SB injection. Numerical rating scale (NRS) showed improvement of Chest pain from point 3 to point 0. Conclusions : This case study suggests that intravenous SB injection may have significant effects of anti-tumor for non-small cell lung cancer.

• Tuberculosis and Respiratory Diseases
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• 제55권5호
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• pp.526-530
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• 2003

기관지성 낭종은 보통 단순 흉부 사진상 폐실질이나 종격동 내에 얇고 때끄러운 벽을 가지며 경계가 뚜렷한 원형의 종괴 흑은 낭포로 발견되고 보통 Hounsfield Number 0-20의 음영을 가진다. 본 증례는 단순 흉부 방사선 소견 상 폐실질내 경계가 불분명한 종괴로 보이고 CT상 Hounsfield Number 26의 연조직 음영을 보여 폐암을 배제하기 위하여 수술까지 하였던 경우였기에 보고하는 바이다.